• Korean Journal of Pharmacognosy
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• v.13 no.1
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• pp.10-13
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• 1982

From the ethereal extract of the roots of Angelica koreana Max. (Umbelliferae) two furanocoumarins such as isooxypeucedanin and oxypeucedanin methanolate were newly isolated together with isoimperatorin, osthol, imperatorin, bergapten, oxypeucedanin and ${\beta}-sitosterol$.

• Korean Journal of Pharmacognosy
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• v.24 no.2
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• pp.111-115
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• 1993

Essential oil of the root of Angelica koreana Max. (Umbelliferae) was investigated. Essential oil was obtained from the dried roots by steam distillation and fractionated by column chromatography. Each isolate or fraction was identified by GC, GC-MS and spectral analysis. It was found to contain nine monoterpenes such as ${\alpha}-pinene$(7.0%), camphene, ${\beta}-pinene$, myrcene, ${\alpha}-phellandrene$, ${\Delta}-3-carene$, p-cymene, limonene(2.8%), terpinolene and also found to contain m-cresol(11.6%), citronellol, citral b, methylcinnamate, eudesmol and osthol. 2-Hydroxy-5-methylacetophenone and twelve compounds were tentatively identified.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.39 no.6
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• pp.537-541
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• 1994

This study was conducted to investigate the possibility of callus induction and plant regeneration from immature inflorescence, stem and petiole of A. koreana MAX. which is worth enough to be used as food and medicine. The callus induction and its proliferation was best when immature inflorescence segments were placed on MS medium supplemented with 2, 4-D 2mg / l. The white and compact embryogenic callus on the surface of dark yellow and soft callus which was induced from immature inflorescence segments came into being only on MS medium with 2, 4-D 1mg /l and 2mg /l, but didn't come into being on the other ones. The shoot came into being effectively from callus derived from immature inflorescence on MS medium mixed 2, 4-D 0. 1mg /l with Kinetin 1mg /l, and 2, 4-D 0.5mg /1 with Kinetin 2mg /l. Immature inflorescence was most appropriate material for callus induction and plant regeneration.

• Journal of Pharmaceutical Investigation
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• v.9 no.4
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• pp.8-12
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• 1979

A study on the effects of the root components of Angelica koreana Max. on voluntary activity in mice has confirmed that: 1. MeOH soluble Ex., MeOH insoluble Ex., oxypucedanine and isoimperatorin were antagonized against the voluntary activity in mice pretreated with a dose of C.N.B. 30mg/kg. 2. MeOH insoluble Ex. showed higher depressant effect than MeOH soluble Ex.. 3. the depressant activity of oxypucedanine was significantly more effective than that of isoimperatorin.

• 한국약용작물학회:학술대회논문집
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• 2007.11a
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• pp.284.1-284.1
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• 2007

• 한국약용작물학회:학술대회논문집
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• 2007.05a
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• pp.97-98
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• 2007

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.197.1-197.1
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• 2003

To investigate biological active constituents from natural products, we have studied the roots of Angelica koreana Max. (Umbelliferae). Fifteen compounds were isolated from the MeOH extract by column chromatography on a silica gel. The compounds were identified as isoimperatorin, oxypeucedanin, oxypeucedanin hydrate, osthol, nodakenin, 2-hydroxy-4-methylacetophenone, cimifugin, falcarindiol, heraclenin, pabulenol, umbelliferone, demethylsuberosin, hamaudol, sec-O-glucosylhamaudol, and prim-O-glucosylcimifugin, respectivelv, by spectroscopic means. Among these, the latter eight compounds were isolated for the first time form this plant.

• 한국약용작물학회:학술대회논문집
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• 2007.05a
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• pp.99-100
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• 2007

• Korean Journal of Plant Resources
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• v.20 no.4
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• pp.331-335
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• 2007

This study was conducted to investigate the soil mulching effect on bolting and growth of Angelica koreana Max. The bolting ratio were 8.4% of non-mulching, 11.4% of black polyethylene film, 13.6% of transparent polyethylene film, 6.4% of rice-straw mulching. The mulching of polyethylene film induced higher bolting response than other materials. The radical leaf length, the number of leaf and crown in black P.E. film mulched were all higher than those of non-mulching and rice-straw mulching. The yield of the underground part of P.E film mulching was higher than non-mulching and rice-straw mulching. Comparing with other treatments, the dry root yield of black P.E. film mulching showed the most.

• YAKHAK HOEJI
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• v.14 no.1_2
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• pp.21-27
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• 1970

Isoimperatorin and Oxypeucedanin isolated from root of Angelica Koreana Max. (Umbelliferae) that is used as "Kang-Whal" a botanical drug, in Korea, Show following general pharmacologic activities. The treatment with Oxypeucedanin on the exercised duodenum of the rabbit increased the motility of it while isoimperatorin shows little effects. But on the exercised heart of the frogs, both components depressed its contractility. Whereas Oxypeucedanin depressed both blood pressure of the carotied artery and respiration of the rabbit, Isoimperatorin tends to increase blood pressure, respiration and the tonus of the muscle of the earth worm. Oxypeucedanin did not affect the tonus of the muscles of the earth worm, but depressed the uterus contraction of the rabbit, which was, on the contrary, increased by Isoimperatorin.