• Title/Summary/Keyword: Analysis of Activity

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A Study of Properties and Coating Natural Mineral Pumice Powder of in Korea (한국산 천연 광물 부석 파우더 코팅 및 특성에 관한 연구)

  • Kim, In-Young;Noh, Ji-Min;Nam, Eun-Hee;Shin, Moon-Sam
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.2
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    • pp.498-506
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    • 2019
  • This study is based on a coating method that provides utilization value as a micronised powder for cosmetic raw materials using natural minerals buried in Bonghwa, Gyeongsangbuk-do in Korea. The mineral powder name is called Buseok, and chemical name is pumice powder. The results of a study on the efficacy of cosmetics are reported by the development of particulate powder to assess the performance of this powder. First of all, in order to coat the surface of this powder with oil, aluminum hydroxide was coated on the particulate surface and then coated with alkylsilan. In addition, it was coated with vegetable oil to prevent condensation of the powder and increase the dispersion in the oil phase. First; the particle size of pumice powder was from 10 to 50mm having porous holes on the surface of the particles. Second; The components of this powder contained $SiO_2$, $Al_2O_3$, $Fe_2O_3$, MgO, CaO, $K_2O_2$, $Na_2O$, $TiO_2$, $TiO_2$, MnO, $Cr_2O_3$, $V_2O_5$. Third: The particles of this powder have a planetary structure and are reddish-brown with porosity through SEM and TEM analysis. Fourth; the far-infrared radiation rate of this parabolic powder was $0.924{\mu}m$, and the radiative energy was $3.72{\times}102W/m^2$ and ${\mu}m$. In addition, the anion emission is 128 ION/cc, which shows that the coating remains unchanged. Based on these results, it is expected to be widely applied to basic cosmetics such as BB cream, cushion foundation, powderfect, and other color-coordinated cosmetics, sunblock cream, wash-off massage pack as an application of cosmetics. (Small and Medium Business Administration: S2601385)

Verification of Anti-Inflammatory Effects of Strawberry (Fragaria x ananassa var. 'Seolhyang') Stems on Macrophages Stimulated by Lipopolysaccharides (LPS로 자극된 대식세포에 대한 딸기 줄기의 항염증 효능 검증)

  • Dan-Hee Yoo;In-Chul Lee
    • Microbiology and Biotechnology Letters
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    • v.51 no.3
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    • pp.280-288
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    • 2023
  • In strawberry farming, most parts of strawberry stems but the fruit have been dumped. Therefore, this study attempted to investigate the antioxidant and anti-inflammatory effects of strawberry stems which are thrown away after farming. For this, strawberry stem extracts were obtained, using hot water and 70% ethanol. First, total polyphenol contents of the hot water and ethanol extract were checked (265.4 ± 0.12 mg TAE/100 g, 503.88 ± 0.2 mg TAE/100 g). For analysis of antioxidant activities, electron donating ability (EDA) and 2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity were measured. Both extracts increased in a dose-dependent fashion, and similar effects with vitamin C (control group) were confirmed. In terms of cell viability of the hot water and ethanol extracts of strawberry stems, 'RAW 264.7' was 99% or higher at 500 ㎍/ml. In addition, cell experiments were conducted at 50, 100 and 500 ㎍/ml where cell viability is above 99%. In terms of inhibition of the inflammatory mediator 'nitric oxide (NO)', the hot water and ethanol extracts of strawberry stems were 37.9% and 38.8% respectively, confirming the inhibition of NO production. To check anti-inflammatory activities, protein and mRNA expressions of 'iNOS' and 'COX-2' were measured, using RAW 264.7. Compared to the LPS group, the protein expression of the inflammatory mediators was inhibited in the hot water and ethanol extract-treated groups. The above results confirmed that the hot water and ethanol extracts of strawberry stems are valuable as natural substances with antioxidant and anti-inflammatory activities.

Mechanisms of Tributyltin-induced Leydig Cell Apoptosis (유기주석화합물이 웅성생식세포주에 미치는 영향)

  • Lee, Kyung-Jin;Kim, Deok-Song;Ra, Myung-Suk;Wui, Seong-Uk;Im, Wook-Bin;Park, Hueng-Sik;Lee, Jong-Bin
    • Environmental Analysis Health and Toxicology
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    • v.18 no.2
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    • pp.89-94
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    • 2003
  • Tributyltin (TBT) used world-wide in antifouling paints for ships is a widespread environmental pollutant and cause reproductive organs atrophy in rodents. At low doses, antiproliferative modes of action have been shown to be involved, whereas at higher doses apoptosis seems to be the mechanism of toxicity in reproductive organs by TBT. In this study, we investigated that the mechanisms underlying DNA fragmentation induced by TBT in the rat leyding cell line, R2C. Effects of TBT on intracellular Ca$\^$2+/ level and reactive oxygen species (ROS) were investigated in R2C cells by fluorescence detector. TBT significantly induced intracellular Ca$\^$2+/ level in a time-dependent manner. The rise in intracellular Ca$\^$2+/ level was followed by a time-dependent generation of reactive oxygen species (ROS) at the cytosol level. Simultaneously, TBT induced the release of cytochrome c from the mitochondrial membrane into the cytosol. Furthermore, ROS production and the release of cytochrome c were reduced by BAPTA, an intracellular Ca$\^$2+/ chelator, indicating the important role of Ca$\^$2+/ in R2C during these early intracellular events. In addition, Z-DEVD FMK, a caspase-3 inhibitor, decreased apoptosis by TBT. Taken together, the present results indicated that the apoptotic pathway by TBT might start with an increase in intracellular Ca$\^$2+/ level, continues with release of ROS and cytochrome c from mitochondria, activation of caspases,and finally results in DNA fragmentation.

The Correlation between Sensory Process Type and Interpersonal Problems, Adult Attachment on University Students (대학생의 감각처리 유형과 대인관계문제 및 성인애착의 관계)

  • Yoon, Su-Jeong;Lee, Chun-Yeop;Kim, Hee-Jung;Jung, Hye-Rim
    • The Journal of Korean society of community based occupational therapy
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    • v.7 no.2
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    • pp.9-18
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    • 2017
  • Objective : This study was to find out the level of sensory process type, adult attachment and interpersonal problems on university students and then to investigate the correlation. Methods : For this study, 169 students who don't know about the evaluation tool in university students of K area in Korea were participated. To execute evaluation, Adolescents/Adults Sensory Profile (AASP) was used for the sensory process type, Short Form of the Korean Inventory of Interpersonal Problems Circumplex Scale (KIIP-SC) was used for interpersonal problems, and Experiences in Close Relationships Scale-Revised (ECR-R) was used for the adult attachment. The correlation between sensory process type and interpersonal problems, adult attachment was analyzed by using pearson correlation analysis. Results : Sensory process type of university students appeared that sensory seeking was lower than general people, and the rest of items showed similar results with general people. For interpersonal problems, there was a lot of difficulty in self-sacrificing and overly accommodating, whereas there was a little difficulty in vindictive and domineering / controlling. For adult attachment, attachment avoiding was more stable than attachment anxiety. Also, low registration and sensory sensitivity all showed positive correlation with interpersonal problems and adult attachment. Among interpersonal problems, self-sacrificing and intrusive showed positive correlation with sensory seeking whereas cold, socially inhibited, nonassertive, and overly accommodating showed positive correlation with sensory avoiding. Thus, sensory seeking and sensory avoiding showed different results (p<.05). Conclusion : In occupational therapy clinic, not only the disabled but non-disabled people that experience issue of interpersonal problems and attachment could be helped with managing high quality social activity if they execute intervention according to sensory process type.

Design Information Management System Core Development Using Industry Foundation Classes (IFC를 이용한 설계정보관리시스템 핵심부 구축)

  • Lee Keun-hyung;Chin Sang-yoon;Kim Jae-jun
    • Korean Journal of Construction Engineering and Management
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    • v.1 no.2 s.2
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    • pp.98-107
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    • 2000
  • Increased use of computers in AEC (Architecture, Engineering and Construction) has expanded the amount of information gained from CAD (Computer Aided Design), PMIS (Project Management Information System), Structural Analysis Program, and Scheduling Program as well as making it more complex. And the productivity of AEC industry is largely dependent on well management and efficient reuse of this information. Accordingly, such trend incited much research and development on ITC (Information Technology in Construction) and CIC (Computer Integrated Construction) to be conducted. In exemplifying such effort, many researchers studied and researched on IFC (Industry Foundation Classes) since its development by IAI (International Alliance for Interoperability) for the product based information sharing. However, in spite of some valuable outputs, these researches are yet in the preliminary stage and deal mainly with conceptual ideas and trial implementations. Research on unveiling the process of the IFC application development, the core of the Design Information management system, and its applicable plan still need be done. Thus, the purpose of this paper is to determine the technologies needed for Design Information management system using IFC, and to present the key roles and the process of the IFC application development and its applicable plan. This system play a role to integrate the architectural information and the structural information into the product model and to group many each product items with various levels and aspects. To make the process model, we defined two activities, 'Product Modeling', 'Application Development', at the initial level. Then we decomposed the Application Development activity into five activities, 'IFC Schema Compile', 'Class Compile', 'Make Project Database Schema', 'Development of Product Frameworker', 'Make Project Database'. These activities are carried out by C++ Compiler, CAD, ObjectStore, ST-Developer, and ST-ObjectStore. Finally, we proposed the applicable process with six stages, '3D Modeling', 'Creation of Product Information', 'Creation and Update of Database', 'Reformation of Model's Structure with Multiple Hierarchies', 'Integration of Drawings and Specifications', and 'Creation of Quantity Information'. The IFCs, including the other classes which are going to be updated and developed newly on the construction, civil/structure, and facility management, will be used by the experts through the internet distribution technologies including CORBA and DCOM.

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Characterization and Formation Mechanisms of Clogging Materials in Groundwater Wells, Mt. Geumjeong Area, Busan, Korea (부산 금정산 일대 지하수공내 공막힘 물질의 특징과 형성원인)

  • Choo, Chang-Oh;Hamm, Se-Yeong;Lee, Jeong-Hwan;Lee, Chung-Mo;Choo, Youn-Woo;Han, Suk-Jong;Kim, Moo-Jin;Cho, Heuy-Nam
    • The Journal of Engineering Geology
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    • v.22 no.1
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    • pp.67-81
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    • 2012
  • The physical, chemical, and biological properties of clogging materials formed within groundwater wells in the Mt. Geumjeong area, Busan, Korea, were characterized. The particle size distribution (PSD) of clogging materials was measured by a laser analyzer. XRD, SEM, and TEM analyses were performed to obtain mineralogical information on the clogging materials, with an emphasis on identifying and characterizing the mineral species. In most cases, PSD data exhibited an near log-normal distribution; however, variations in frequency distribution were found in some intervals (bi-or trimodal distributions), raising the possibility that particles originated from several sources or were formed at different times. XRD data revealed that the clogging materials were mainly amorphous ironhydroxides such as goethite, ferrihydrite, and lapidocrocite, with lesser amounts of Fe, Mn, and Zn metals and silicates such as quartz, feldspar, micas, and smectite. Reddish brown material was amorphous hydrous ferriciron (HFO), and dark red and dark black materials were Fe, Mn-hydroxides. Greyish white and pale brown materials consisted of silicates. SEM observations indicated that the clogging materials were mainly HFO associated with iron bacteria such as Gallionella and Leptothrix, with small amounts of rock fragments. In TEM analysis, disseminated iron particles were commonly observed in the cell and sheath of iron bacteria, indicating that iron was precipitated in close association with the metabolism of bacterial activity. Rock-forming minerals such as quartz, feldspar, and micas were primarily derived from soils or granite aquifers, which are widely distributed in the study area. The results indicate the importance of elucidating the formation mechanisms of clogging materials to ensure sustainable well capacity.

A Study on Development of Achievement Standards and Assessment Standards of Vocational Inquiry Section for 2005 College Scholastic Ability Test - Focus on Food and Nutrition Subject in the Field of Home Economics Order - (2005 수능 직업탐구영역의 과목별 성취기준과 평가기준 개발 - 식품과 영양 과목을 중심으로 -)

  • Na Hyeon-Ju;Min Kyung-Hee;Lee Hwa-young;Pyo Jum-sun;Ha Mi-ok;Jang Myung-Hee
    • Journal of Korean Home Economics Education Association
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    • v.17 no.2
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    • pp.197-219
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    • 2005
  • This study attempted, in accordance with the National Educational Curriculum, to develop achievement assessment standards for a course within the field of home economics which has been widely adopted by Korean vocational high schools, namely, the food and nutrition subject. Focus was also placed on strengthening the management of the curriculum for this food and nutrition course, as well as on establishing proper assessment standards by developing model assessment tools which can be used to assess the subject. The results of this study can be summarized as follows : First, based on an analysis of the related literature and materials. the desired notion of the achievement and assessment standards was established, and their significance ascertained the achievement and assessment standards for the food and nutrition course were set and the type of model assessment tool which should be developed, as well as the method in which it should be applied. was established Second. by analyzing the curriculums and the contents of the textbooks used in the food and nutrition subject, the researcher was able to compile the 70 factors which could to be used to develop the achievement and assessments standards, and then classify these into 6 main categories and 32 sub-categories. Based on the characteristics of these factors and learners' academic performance levels the number of factors was expanded to 89 in order to establish the achievement standards. In turn, these achievement standards were used, in accordance with the learners' achievement and teaming activity levels, to develop three different levels of assessment standards. namely, upper, middle, and lower ones. Third. a model assessment tool was developed which could be used by individual school units as a reference in terms of achievement and assessment standards, and that could be modified to meet each school's circumstances. In order to create the model assessment tool a 100-question questionnaire was formulated that contained various types of questions, such as essay, report, theoretical and practical, portfolio, as well as multiple choice-type questions. Lastly, the researcher introduced measures to effectively use the achievement and assessment standards developed for the food and nutrition course, as well as the model assessment tool in school units.

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Production of GABA-rich Tomato Paste by Lactobacillus sp. Fermentation (유산균 발효에 의한 GABA 함유 토마토 페이스트의 생산)

  • Cho, Seok-Cheol;Kim, Dong-Hyun;Park, Chang-Seo;Koh, Jong-Ho;Pyun, Yu-Ryang;Kook, Moo-Chang
    • The Korean Journal of Food And Nutrition
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    • v.25 no.1
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    • pp.26-31
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    • 2012
  • For the purpose of production of GABA-rich tomato paste, this study was carried out to investigate GABA producing lactic acid bacteria from Korean traditional fermented food, Kimchi and optimize the culture conditions. As a result of fermentation, Lactobacillus brevis B3-20 among lactic acid bacteria isolated at the pre-experiments was the best producer of GABA at the tomato paste medium with 50%(wet-base) levels of dionized water. At the result of fermentation on the tomato paste medium with 0.5%(w/w) yeast extract, as a source of nitrogen, 3%(w/w) MSG(monosodium glutamate) and dionized water(the ratio of tomato paste and water was 2:8), Lb. brevis B3-20 produced the maximum GABA concentration, 143.38 mM. GABA-rich tomato paste showed the activity of free radical scavenging. Because GABA-rich tomato paste have functional ingredients such as ascorbic acid, lycopene, carotenoid, as well as GABA by lactic acid bacteria fermentation, GABA-rich tomato paste can be considered high functional materials.

The Study of Antioxidant Properties, and Physicochemical and Sensory Characteristics of Steamed Barley Bread added with Ramie Leaf (모싯잎 가루를 첨가한 찰보리 찐빵의 항산화 활성, 이화학적 특성 및 관능적 품질 특성에 관한 연구)

  • Kim, Ji-Hyun;Kim, Se-Jung;Yun, Jung-Mi
    • The Korean Journal of Food And Nutrition
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    • v.27 no.2
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    • pp.249-255
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    • 2014
  • Increased consumption of a polysaccharide, ${\beta}$-glucans, in foods may prevent health related problems such as cancer, cardiovascular diseases and diabetes. ${\beta}$-glucans is a fibrous polysaccharide having proven both functional and medicinal properties. Recently, the FDA recommends the consumption of oat or oat products containing a total of at least 3 grams of bea-glucans per day for health improvement. The content of ${\beta}$-glucans in barley was almost four times higher than that in oat. In this study, the physicochemical and sensory characteristics and biological properties of steamed barley bread added with ramie leaf powder was investigated. The study of sensory characteristics was performed using the Quantitative Descriptive Analysis (QDA). 30 panelists were selected among our university students. They then evaluated the different sensory characteristics, such as overall preference, color, flavor, chewiness, moistness and taste. The color and texture analyses were determined using a colorimeter and texture analyser, respectively. In the sensory, color and texture evaluation, barley bread with ramie leaf showed higher values than barley bread and wheat bread did. The physiological activities were investigated through the total phenol content and 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical scavenging activity. Hence, barley appears to be a suitable food resource for making bread. This study suggests that barley bread added with ramie leaf can be used as one of the processing methods in promoting the consumption of barley. It might also help with the improvement of barley food industry.

Phosphorus Modified Co/Al2O3 Fischer-Tropsch Catalyst for a Slurry Phase CSTR with Enhanced Hydrothermal and Mechanical Stability (수열특성 및 기계적 안정성의 개선으로 슬러리상 CSTR에 적합한 P 첨가 알루미나 기반의 Fischer-Tropsch 합성용 코발트 촉매)

  • Jung, Gyu-In;Ha, Kyoung-Su;Park, Seon-Ju;Kim, Du-Eil;Woo, Min-Hee;Jun, Ki-Won;Bae, Jong-Wook;Kang, Yong
    • Korean Chemical Engineering Research
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    • v.50 no.2
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    • pp.229-237
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    • 2012
  • Phosphorus was incorporated into Co/$Al_2O_3$ catalyst for FTS by impregnating an acidic precursor, phosphoric acid, in ${\gamma}-Al_2O_3$ support to improve the mechanical strength, the hydrothermal stability of the catalyst particle, and the catalytic performance as well. Surface characterization techniques such as FT-IR revealed that $AlPO_4$ phase was generated on the surface of the P-modified catalyst. The addition of phosphorus was found to alleviate the interaction between cobalt and alumina surface, and to increase reducibility of catalyst. The catalytic activity such as $C_{5+}$ productivity and turnover frequency (TOF) was calculated to evaluate catalytic performance. The influence of calcination temperature of the $Al_2O_3$ containing 2 wt.% P on the catalytic performance was also investigated. Through hydrothermal stability test and XRD analysis, the P-modified catalyst had strong resistant to the pressurized and hot $H_2O$. The mechanical strength of the P-modified catalyst was also examined through an in-house fluidized-bed vessel, and it was found that the catalyst fragmentation could be successfully suppressed with P. Taken as a whole, the best performance was shown to be at 1~2 wt.% P in alumina and at the calcination temperature of $500^{\circ}C$.