• International Journal of Stem Cells
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• 제17권2호
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• pp.182-193
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• 2024

To address the limitations of animal testing, scientific research is increasingly focused on developing alternative testing methods. These alternative tests utilize cells or tissues derived from animals or humans for in vitro testing, as well as artificial tissues and organoids. In western countries, animal testing for cosmetics has been banned, leading to the adoption of artificial skin for toxicity evaluation, such as skin corrosion and irritation assessments. Standard guidelines for skin organoid technology becomes necessary to ensure consistent data and evaluation in replacing animal testing with in vitro methods. These guidelines encompass aspects such as cell sourcing, culture techniques, quality requirements and assessment, storage and preservation, and organoid-based assays.

• 한국시뮬레이션학회논문지
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• 제10권1호
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• pp.51-62
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• 2001

For the productivity improvement, it is necessary to analyze problem of the system and evaluate alternative plans. But, it if hard to experiment and evaluate alternative plans in real existing system. Therefore, it is necessary to synthetically analyze and evaluate alternative plans using simulation and statistical analysis method. In this case study, as a simulation language, Promodel is used to compare and evaluate four alternatives which are considered to improve the productivity of an object system. The object system is constituted of a pretreatment line and a painting line. The purpose of this study is to analyze whether the decrease of the down time in pretreatment line can be effective to the productivity improve comparing with exiting system and other alternatives. The other purpose is to choose an alternative that has the best productivity improvement. The results of the simulation show that the possibility of improvement in productivity by decreasing the down time of pretreatment line. Two-Stage Bonferroni Procedure is used to choose the best alternative.

• 한국산업정보학회논문지
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• 제13권5호
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• pp.124-132
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• 2008

본 연구는 균형성과지표와 6시그마 추진기업의 6시그마 프로젝트 평가시스템을 통합한 프로젝트 평가시스템의 대안을 제시하고 있다. 균형성과지표 차원의 재무, 고객, 내부 프로세스, 학습과 성장 4개의 관점에서 목표와 평가지표를 토대로 재무관점의 4개, 고객관점의 6개, 내부 프로세스 관점의 5개, 학습과 성장관점의 6개의 평가지표가 연구결과이다. 본 연구의 결과는 실무적으로 적용가능한 지표이며 향후 연구과제로는 특정기업에서 본 지표를 바탕으로 검증연구 및 전략적 체계도와 연계한 통합 시스템에 관한 연구이다.

• 한국전자거래학회지
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• 제17권2호
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• pp.165-187
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• 2012

방송통신 연구개발 과제 관리 및 평가 체계의 개선 필요성이 증대되고 있다. 이미 해외 주요국과 국내 정부 및 연구기관에서는 개선에 대한 필요성을 공감하고 구체적인 지표 개발 방안을 모색 중이다. 이러한 추세에 부응하기 위해 본 연구에서는 연구개발 과제 성과평가지표 및 척도를 개발하여 현행 체계의 단점을 극복하고자 하였다. 본 연구의 특징으로 연구개발 과제의 가치에 대한 두 가지 관점을 정리하고 국내외 주요 기관들의 평가지표와 척도를 분류, 종합함으로써 보다 체계적이고 효율적인 지표를 개발하고자 하였다. 동시에 산/학/연의 전문가들의 참여를 통해 지표와 척도 내용을 방송통신 환경에 적합하도록 조정하였다. 본 연구에서 개발된 방송통신 연구성과 측정 지표 및 척도는 보다 객관적이고 체계적인 연구성과 평가에 기여할 것으로 판단된다.

• 한국지능시스템학회논문지
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• 제12권2호
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• pp.157-163
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• 2002

본 연구의 목적은 배치 특성의 정량화에 의해 배치 대안들을 비교할 수 있는 객관적인 평가 기준을 정림하는 것이다. 장비배치는 모든 구성 요소들의 기능을 최대로 하고 동시에 공간적인 제한 조건을 만족시키도록 여러 가지 장비들의 위치를 결정하는 설계단계이다. 선박의 경우 설계자가 제시하는 몇 가지 배치안 중 한 가지만 선택하게 되는데 이 과정은 숙련된 전문가의 경험, 지식, 판단에 대한 의존도가 매우 높고 또한, 객관적인 평가가 어렵다. 우리는 이러한 서술적인 언어로 된 것을 퍼지 이론을 통해 정량화하여 배치안을 객관적으로 평가할 수 있는 기준을 제시한다.

• 한국생산제조학회지
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• 제19권4호
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• pp.521-528
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• 2010

A product system will be improved continually until requirements are satisfied. It is true that considering alternative designs to improve product system is hard work; it is also true that selecting an adequate design idea that represents the needs of stakeholders concerned and meets effectiveness factors properly is not an easy work, either. In the process of driv-ing an idea and designing, which is called Design Phase, there are lots of existing tools for testing the driven idea in DFSS. But, those kinds of tools do not offer the function that helps to select the technically better design idea among alternative design ideas that have the same evaluation level. Moreover it is inappropriate to select adequate alternative design ideas by just verifying only the evaluation table in pugh matrix, since satisfied deviation val-ues are low when there is a too competitive mass product system in a market. Also, for the IT product with short life cycle, faster and more effective testing tool is needed. Therefore, the 'roduct quality index' is suggested in order to select an appropriate candidate design concept for system development that meets requirements by using 'deality concept' pro-vided by TRIZ. According to the result of this research, it is possible to select technically better idea fast and effectively; it is confirmed by applying the approach to the case of LCD BLU (Back Light Unit).

• 디지털산업정보학회논문지
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• 제9권3호
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• pp.173-185
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• 2013

In this study, the relationships of factors influencing the ways alternative types of new digital products are accepted into the market will be structuralized. On the basis of previous research, it is assumed that customers intend to use alternative types of new digital products when they have a higher value than existing products. The consumer's feeling of attraction toward the product is another factor included in the evaluation of its quality. And the attraction of the products that the consumers feel is also included in the evaluation of the qualities of the product. The results of the study indicate first that a product's value affects its attraction, but not the usage intention of the customer. Second, the benefits of the product affect the customer's recognition of its value, while cost does not. Third, environment affects recognition by the customer of the product's attraction, while knowledge of the product does not. By structuralizing the factors that influence the customer's usage intention about alternative types of new digital devices, the causal relationships of the factors involved in the acceptance of new products into the market and their success can be comprehended.

• 한국식품영양학회지
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• 제29권4호
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• pp.557-564
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• 2016

This study was performed to develop and evaluate beverage prepared with optimally roasted seoritae to maximize the isoflavone content and antioxidant activities of the beverage. Isoflavone content was maximized at the roasting temperature of $110^{\circ}C$ for 20 min. Both DPPH radical scavenging activity and ABTS radical scavenging activity along with total polyphenol content were highest when seoritae was roasted at $110^{\circ}C$ for 20 min. Western blotting was used to determine the level of nuclear factor of activated T-cells 1(NFATc1) involved in controlling osteoclast differentiation. The results showed that NFATc1 had a concentration-dependent inhibitory effect when the RoS110 (roasted seoritae at $110^{\circ}C$ for 20 min) samples were processed at varying concentrations (10, 50, and $100{\mu}g/mL$). Tea samples were prepared from optimally roasted seoritae by varying brewing times (5~90 min) at $65^{\circ}C$, and tea brewed for 60 min had the highest preference with $65^{\circ}C$ as the preferred temperature for drinking.

• 한국IT서비스학회지
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• 제11권3호
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• pp.1-16
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• 2012

This paper is aimed to present a fuzzy decision-making approach to deal with disaster recovery priority decision problem in information system. We derive an evaluation approach based on TOPSIS(Technique for Order Performance by Similarity to Ideal Solution), to help disaster recovery priority decision of total information system for port logistics in a fuzzy environment where the vagueness and subjectivity are handled with linguistic terms parameterized by trapezoidal fuzzy numbers. This study applies the fuzzy multi-criteria decision-making method to determine the importance weight of evaluation criteria and to synthesize the ratings of candidate disaster recovery system. Aggregated the evaluators' attitude toward preference, then TOPSIS is employed to obtain a crisp overall performance value for each alternative to make a final decision. This approach is demonstrated with a real case study involving 4 evaluation criteria(system dependence, RTO, loss, alternative business support), 7 information systems for port logistics assessed by 5 evaluators from Maritime Affairs and Port Office.

• 수산해양교육연구
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• 제23권3호
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• pp.503-514
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• 2011

Port Authority in Korea does not have financial independence nor fair recruitment practices, thus the prospects of the establishment of the Port Authority is not adequate. Therefore independent and effective port administration cannot be achieved. To overcome this situation, this paper examines the port administration system in Korea and identifies its problems. This paper then provides an 'modeling of Analytical Hierarchy structure' for evaluation. An alternative solution is provided by carrying out a public survey, analysing the significance of the evaluation factor using the techniques of the Analytical Hierarchy Process. The significance of profitability was identified. The role of central government is significant when assessing the public service function of port administration; and the role of the private company is significant when assessing the independence. In addition, the private company is significant when assessing profitability. The private company is the alternative for port administration in Korea, based on the evaluation of various alternatives.