• Korean Journal of Materials Research
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• v.24 no.1
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• pp.48-52
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• 2014

The Mg-enriched magnesium aluminum silicate (MAS) glass is known for its higher mechanical strength and chemical resistance. Among such glasses, cordierite ($Mg_2Al_4Si_5O_{18}$) is well known to have a low thermal expansion and low melting point. Polycrystalline engineering ceramics such as alumina can be strengthened by a surface modification with low thermal expansion materials. The present study involves the synthesis of cordierite by a sol-gel process and investigates the effect of glass penetration on the surface of alumina. The cordierite powders were prepared from $Al(OC_3H_7)_3$, $Mg(OC_2H_5)_2$ and tetraethyl orthosilicate by hydrolysis and condensation reaction. The cordierite powders were characterized by X-ray diffraction (XRD, Rigaku), scanning electron microscope (SEM, JEOL: JSM-5610), energy dispersive spectroscopy (EDS, JEOL: JSM-5610), and universal testing machine (UTM, INSTRON). The X-ray diffraction patterns showed that the synthesized particles were ${\mu}$-cordierite calcined at $1100^{\circ}C$ for 1 h. The shape of synthesized cordierite was changed from ${\mu}$-cordierite to ${\alpha}$-cordierite with increasing calcination temperature. Synthesized cordierite was used for surface modification of alumina. Cordierite powders penetrated deeply into the alumina sample along grain boundaries with increasing temperature. The results of surface modification tests showed that the strength of the prepared alumina sample increased after surface modification. The strength of a surface modified with synthesized cordierite increased the most, to about 134.6MPa.

• Journal of Acupuncture Research
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• v.24 no.4
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• pp.167-181
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• 2007

Objectives: To evaluate expression of MIF mRNA, MIF, $TNF-{\alpha}$, $IL-6R-{\alpha}$, STAT-3, $NF-{\kappa}B$ p65, COX-2 and iNOS, MMP-9mRNA after injecting deer antler herbal acupuncture solution in a LPS rat model. Methods: The experiment was divided in category of the control group, RA group, and NA group. RA was induced in the mice via injecting 300ug/kg LPS. The deer antler herbal acupuncture solution 50ug/kg was applied on $ST_{35}$(犢鼻) and EX-LE201(內膝眼) for 19days from $3^{rd}$ day of RA inducement. Results: 1. In the deer antler herbal acupuncture solution treated RAW 264.7cell, the mRNA expression of cytokines, RA related inflammation factors, such as the MIF, COX- 2, iNOS, and MMP-g reduced concentration dependently. 2. In the deer antler herbal acupuncture treated mice's synovial membrane, decrease in the cell replication of synovial joint cells, regeneration of blood vessel, fibrosis and fibroblastic cells expansion were observed. 3. Positive reaction of RA-related cytokines MIF, $TNF-{\alpha}$, $IL-6R-{\alpha}$, STAT3, COX-2, iNOS, $NF-\;{\kappa}B$ p65, MMP-9 was reduced. Conclusion : On the basis of the results, it was concluded that deer antler herbal acupuncture extract has significant protecting ability against acute progressive RA by inhibiting the production of MIF, as a top in cytokines related to inflammation.

• Journal of the Korean Chemical Society
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• v.37 no.1
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• pp.119-130
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• 1993

The stereochemistry of 1,3-thiazolidine sulfoxides 1 in which 3 chiral centres are present in a molecule was elucidated by deuterium exchange and trapping reactions. 3-Acetoxy-1,3-thiazolidines 5 was oxidized to 6 and 8, corresponding $\alpha$-cis 10, $\alpha$-trans 11, $\beta$ -cis 12, and $\beta$ -trans 13 isomers were separated from their diasteromeric mixtures. Sulfoxide 10 was isomerized to more thermodynamically stable isomer 13 under neutral conditions in refluxing benzene or toluene. The methyl hydrogens of 2-methyl group in the sulfoxide 13 and those of the sulfoxide 11 were deuterated by the deuterium incorporation reactions. The intermediate sulfenic acids 25 and 26 derived from the sulfoxides 10 and 12 via sigmatropic rearrangement were trapped by 2-mercaptobenzothiazole (2-MBT) to give disufides 27 and 28 respectively. However, the sulfoxides 11 and 13 were transformed to ring expansion product dihydro-1,4-thiazine 29 under the same reaction conditions. In the presence of acid catalyst, the sulfoxides 10, 11, and 12 were converted to dihydro-1,4-thiazine 29 through the sulfoxide 13 quantitatively. The mechanisms of isomerization of sulfoxides and the formation of 29 were also discussed.

• Journal of the Korean Geosynthetics Society
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• v.12 no.4
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• pp.87-98
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• 2013

This study was performed a series of the isotropic compression-expansion tests and the drained triaxial tests with various the relative densities 40%, 60%, 80% and 95% for bottom ash. Using the tests results the characteristic of the parameters of Lade's single hardening constitutive model were investigated. The soil parameters Kur and n representing elastic behavior are not much affected by the change of the relative density. The other parameters such as failure criterion(m, ${\eta}_1$), hardening function(c, p) and plastic potential(${\psi}_2$, ${\mu}$) are in a positive linear relationship with the relative density. Since the soil parameters h and ${\alpha}$ representing yield function do not change much to the change of relative density and also closely related to failure criterion, they can be replaced by failure criterion ${\eta}_1$. We also observed that predicted values from the Lade's single hardening constitutive model were well consistent with the observed data.

• Journal of the Korean Applied Science and Technology
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• v.32 no.3
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• pp.522-527
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• 2015

We applied a displacement current measurement technique for the study of L-${\alpha}$-dilauryl phosphatidylcholine (DLPC) monolayer. Displacement current was generated at the DLPC monolayer on the water surface, while induced by compression and expansion of the monolayer. Generation of Maxwell displacement current (MDC) was observed when surface areas per DLPC molecule were approximately $200{\AA}^2$ and $40{\AA}^2$. We investigated MDC for monolayer compression cycles, and found that MDC reached the maximum at the molecular area, which was measured right before surface pressure began to increase during compression cycles. The monolayer surface morphology of Langmuir-Blodgett (LB) films was characterized using atomic force microscope (AFM). As a result, we measured the result from the microscopic properties shown in the AFM images of LB films that molecules in the monolayer were in good orientations and the thickness of the monolayer ranged from 5 to 10 nm.

• Journal of The Korean Astronomical Society
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• v.47 no.6
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• pp.259-277
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• 2014

G192.8-1.1 has been known as one of the faintest supernova remnants (SNRs) in the Galax until the radio continuum of G192.8-1.1 is proved to be thermal by Gao et al. (2011). Yet, the nature of G192.8-1.1 has not been fully investigated. Here, we report the possible discovery of faint non-thermal radio continuum components with a spectral index ${\alpha}{\sim}0.56(S_{\nu}{\propto}{\nu}^{-{\alpha}})$ around G192.8-1.1, while of the radio continuum emission is thermal. Also, our Arecibo $H_I$ data reveal an $H_I$ shell, expanding with an expansion velocity of $20-60km\;s^{-1}$, that has an excellent morphological correlation with the radio continuum emission. The estimated physical parameters of the $H_I$ shell and the possible association of non-thermal radio continuum emission with it suggest G192.8-1.1 to be an~0.3 Myr-old SNR. However, the presence of thermal radio continuum implies the presence of early-type stars in the same region. One possibility is that a massive star is ionizing the interior of an old SNR. If it is the case, the electron distribution assumed by the centrally-peaked surface brightness of thermal emission implies that G192.8-1.1 is a "thermal-composite" SNR, rather than a typical shell-type SNR, where the central hot gas that used to be bright in X-rays has cooled down. Therefore, we propose that G192.8-1.1 is an old evolved thermal-composite SNR showing recurring emission in the radio continuum due to a nearby massive star. The infrared image supports that the $H_I$ shell of G192.8-1.1 is currently encountering a nearby star forming region that possibly contains an early type star(s).

• Journal of Korean Society on Water Environment
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• v.33 no.6
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• pp.696-714
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• 2017

Simple material budget models were developed to predict the spring season (March ~ May) water quality for a river-type reservoir Paldang, in the Republic of Korea. These models are available at mixed water bodies whose light intensity is negligible at the bottom. The calculated data from the models fit quite well with field data collected for 30 years, from 1988 to 2017. The apparent settling velocity of total phosphorus was estimated to be $110m\;d^{-1}$. The critical hydraulic load that determines the usability of phosphorus for algal production appeared to be about $2.0m\;d^{-1}$. When a hydraulic load was larger than the critical value, the concentrations of chlorophyll ${\alpha}$ ($Chl.{\alpha}$), chemical oxygen demand (COD), and 5-day biochemical oxygen demand BOD in the reservoir water became insensitive to internal algal reactions. The model analysis showed that the allochthonous COD continued to increase while the allochthonous BOD slightly decreased after 1999. The decrease of allochthonous BOD is due to the expansion of sewage and wastewater treatment plants in the watershed. The increase of allochthonous COD seems to result from the increase in anthropogenic non-point sources as well as the increase in the discharge of natural organic matters due to climate change. Organic matter of algal origin continued to increase until the mid-2000s, but recently it has decreased as the phosphorus concentration has decreased. The COD and BOD of algal origin increased from 35 % and 27 % during 1988 ~ 1994 to 43 % and 40 % during 2000 ~ 2010, respectively, and then decreased to 25 % and 28 % during 2011 ~ 2017.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.1C
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• pp.11-17
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• 2011

This study was performed a series of the isotropic compression-expansion tests and the drained triaxial tests with various the relative densities 25%, 50%, 80% and 100% for Baekma river sand. Using the tests results the characteristic of the parameters of Lade's single hardening constitutive model were investigated. The soil parameters Kur and n representing elastic behavior are not much affected by the change of the relative density. The other parameters such as failure criterion (m, ${\eta}_1$), hardening function (C, p) and plastic potential (${\Psi}_2$, ${\mu}$) are in a positive linear relationship with the relative density. Since the soil parameters h and $\alpha$ representing yield function do not change much to the change of relative density and also closely related to failure criterion, they can be replaced by failure criterion ${\eta}_1$. We also observed that predicted values from the Lade's single hardening constitutive model were well consistent with the observed data.

• Korean Journal of Materials Research
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• v.9 no.6
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• pp.599-603
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• 1999

We have investigated the growth characteristics of thick GaN on Sim substrate with AlN and low temperature GaN buffer layer. The vertical hydride vapor phase epitaxy system with $GaCl_3$ precursor was used for growth of GaN. AlN and GaN buffer layer were deposited on Si substrate to reduce the lattice mismatch and the thermal expansion coefficient mismatch between si and GaN. Optimization of deposition condition for AlN and low temperature GaN buffer layers were carried out. We studied the effects of growth temperature, V/III ratio on the properties of thick GaN. Surface morphology, growth rate and crystallinity of thick GaN were measured using Atomic Force Microscopy (AFM), $\alpha-step$-, Scanning Electron Microscopy (SEM) and X-Ray Diffractometer(XRD).

• Microbiology and Biotechnology Letters
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• v.44 no.1
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• pp.89-97
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• 2016

Obesity is caused by excess accumulation of body fat and contributes to various pathological disorders such as diabetes, hypertension, cardiovascular disease, and cancer. In this study, we investigated the effect of a 30% ethanol extract of Fructus Rosae laevigata (RLE) on adipogenesis in 3T3-L1 adipocytes, measured by triglyceride accumulation and expression of adipogenesis-related transcription factors during differentiation of pre-adipocytes into adipocytes. RLE decreased the intracellular triglyceride contents (assessed by Oil Red-O staining) in a dose-dependent manner. It also downregulated the expression of adipogenic transcription factors and inhibited cell proliferation during the mitotic clonal expansion phase of adipocyte differentiation by inducing G1 phase arrest. We investigated the alterations in the levels of G1 phase arrest-related proteins. The expression of p21 protein significantly increased, while the levels of Cyclin E, Cdk2, and phospho-Rb decreased in a dose-dependent manner in 3T3-L1 cells treated with RLE. These results suggest that RLE inhibits the differentiation of 3T3-L1 adipocytes by suppressing the expression of adipogenic transcription factors and inducing G1 phase arrest in the early stages of adipocyte differentiation.