• Title/Summary/Keyword: Aligarh

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In vitro antifilarial potential of the leaves and stem extract of Pluchea lanceolata on the cattle filarial parasite Setaria cervi

  • Mishra, Vandna;Parveen, Nazneen;Khan, Nizam U.;Singhal, KC
    • Advances in Traditional Medicine
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    • v.5 no.2
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    • pp.110-116
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    • 2005
  • The effect of alcohol and aqueous extracts of the leaves and stem of Pluchea lanceolata on the spontaneous movements of both the whole worm and the nerve muscle preparation of Setaria cervi, and on the survival of microfilariae in vitro was studied. Alcohol and aqueous extracts of the leaves and stem of P. lanceolata caused the inhibition of spontaneous movements of the whole worm and the nerve muscle preparation of S. cervi, characterized by short lasting small increase in tone and amplitude of contractions followed by paralysis. The concentrations required to inhibit the movements of whole worm and nerve muscle preparations for alcohol extract were 200 and $25\;{\mu}g/ml$, and for aqueous extract were 250 and $100\;{\mu}g/ml$, respectively, suggesting a cuticular permeability barrier. Both the extracts (alcohol and aqueous) caused death of microfilariae in vitro, $LC_{50}$ and $LC_{90}$ being 12 and 18 ng/ml for alcohol extract and 25 and 40 ng/ml for aqueous extract, respectively.

Retrieval of a separated nickel-titanium instrument using a modified 18-guage needle and cyanoacrylate glue: a case report

  • Andrabi, Syed Mukhtar-Un-Nisar;Kumar, Ashok;Iftekhar, Huma;Alam, Sharique
    • Restorative Dentistry and Endodontics
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    • v.38 no.2
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    • pp.93-97
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    • 2013
  • During root canal preparation procedures, the potential for instrument breakage is always present. When instrument breakage occurs, it leads to anxiety of the clinician and as well as a metallic obstruction of the canal which hinders further cleaning and shaping. Separated instruments must always be attempted for retrieval and if retrieval is not possible bypass should be tried. With the increased use of nickel-titanium (NiTi) instruments the incidence of separated instruments has increased. A considerable amount of research has been done to understand the various factors related to the fracture of NiTi instruments to minimize its occurrence. This paper presents a review of the literature regarding the fracture of NiTi instruments and also describes a case report showing the use of a modified 18-guage needle and cyanoacrylate glue to retrieve a separated NiTi instrument from the mesiolingual canal of a mandibular first molar.

Invitro antifilarial potential of the leaf extract of Oscimum sanctum on cattle filarial parasite Setaria cervi

  • Waseem, Rizvi;K.C., Singhal;Nakhat, Haider;Anil, Kumar
    • Advances in Traditional Medicine
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    • v.4 no.1
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    • pp.53-59
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    • 2004
  • The effect of aqueous and alcoholic extract of the leaves of Ocimum. sanctum was studied on the spontaneous movements of the whole worm (w.w) preparation and nerve muscle (n.m.) complex of Setaria cervi (S. cervi) and on the survival of microfilariae (m.f.) in vitro. Both the extracts caused inhibition of the spontaneous motility of the w.w. and n.m. complex of S. cervi characterized by initial stimulation followed by reversible paralysis, aqueous extract at a higher concentration showed immediate effect and irreversible paralysis. The concentration required to inhibit the movements of n.m. complex was $1/4^{th}$ for aqueous and $1/3^{rd}$ for alcoholic extract compared to that for the w.w., suggesting a cuticular permeability barrier. On the m.f. the lethal concentration (LC 50 and LC 90) were 35 and 50 ng/ml for aqueous whereas, 60 and 85 ng/ml for alcoholic extracts respectively.

Antidiarrhoeal activity of Arque-Ajeeb, a compound formulation of Unani medicine in rats

  • Khan, M. Aleem;Khan, Naeem A.;Qasmi, Iqbal A.;Ahmad, Ghufran;Zafar, Shadab
    • Advances in Traditional Medicine
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    • v.4 no.2
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    • pp.87-90
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    • 2004
  • The efficacy of Arque-Ajeeb (AA), a compound formulation of Unani medicine was investigated for antidiarrhoeal activity against barium sulphate-induced gut motility and castor oil-induced diarrhoea in rats. The control, standard and test groups of experimental animals were administered with distilled water (p.o.), lomotil (p.o.) and AA (0.007 ml and 0.014 ml/100 g, p.o.) respectively. Barium sulphate and castor oil were administered after 15 and 60 min respectively in each group of first and second experiment. The distance traveled by barium sulphate in small intestine was measured after 15 and 30 min of barium sulphate administration and diarrhoea was observed every 30-min for six hour after castor oil administration. Oral administration of AA caused significant reduction in diarrhoea. AA may have the potential to reduce the diarrhoea in rats.

Performance of self-compacting concrete at room and after elevated temperature incorporating Silica fume

  • Ahmad, Subhan;Umar, Arshad;Masood, Amjad;Nayeem, Mohammad
    • Advances in concrete construction
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    • v.7 no.1
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    • pp.31-37
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    • 2019
  • This paper evaluates the workability and hardened properties of self-compacting concrete (SCC) containing silica fume as the partial replacement of cement. SCC mixtures with 0, 2, 4, 6, 8 and 10% silica fume were tested for fresh and hardened properties. Slump flow with $T_{500}$ time, L-box and V-funnel tests were performed for evaluating the workability properties of SCC mixtures. Compressive strength, splitting tensile strength and modulus of rupture were performed on hardened SCC mixtures. Experiments revealed that replacement of cement by silica fume equal to and more than 4% reduced the slump flow diameter and increased the $T_{500}$ and V-funnel time linearly. Compressive strength, splitting tensile strength and modulus of rupture increased with increasing the replacement level of cement by silica fume and were found to be maximum for SCC mixture with 10% silica fume. Further, residual hardened properties of SCC mixture yielding maximum strengths (i.e., SCC with 10% silica fume) were determined experimentally after heating the concrete samples up to 200, 400, 600 and $800^{\circ}C$. Reductions in hardened properties up to $200^{\circ}C$ were found to be very close to normal vibrated concrete (NVC). For 400 and $600^{\circ}C$ reductions in hardened properties of SCC were found to be more than NVC of the same strength. Explosive spalling occurred in concrete specimens before reaching $800^{\circ}C$.

Determination of levels of nitric oxide in smoker and nonsmoker patients with chronic periodontitis

  • Wadhwa, Deepti;Bey, Afshan;Hasija, Mukesh;Moin, Shagufta;Kumar, Arun;Aman, Shazia;Sharma, Vivek Kumar
    • Journal of Periodontal and Implant Science
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    • v.43 no.5
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    • pp.215-220
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    • 2013
  • Purpose: Cigarette smoking is a major risk factor in periodontal diseases. The pathogenesis of periodontal diseases may be affected by alterations of the inflammatory response by smoke. Nitric oxide (NO) is a gaseous, colorless, highly reactive, short-lived free radical with a pivotal role in the regulation of various physiological and pathological mechanisms in the body. It is important in host defense and homeostasis, on the one hand, whereas, on the other hand, it modulates the inflammatory response in periodontitis, leading to harmful effects. The aim of this study was to assess the levels of NO in both the serum and saliva of smokers and nonsmokers having chronic periodontitis and to compare them with periodontally healthy controls. Methods: Sixty subjects participated in the study and were divided into three groups: group I, healthy nonsmoking subjects; group II, nonsmoking patients with chronic periodontitis; group III, smoking patients with chronic periodontitis. Each group consisted of twenty subjects. The biochemical estimation of NO in the collected serum and in the saliva was performed using the Griess colorimetric reaction. Results: The results showed that the mean value of the salivary and serum NO was greater in group II than in group I, and also greater in group III than in group II. Conclusions: NO appears to play an important and rather complex role in the immuno-inflammatory process and in the remodeling and maintenance of osseous structures. It is therefore logical that modulation of this mediator has potential for the treatment of a number of inflammatory conditions including periodontal disease.

Antifilarial potential of the root extracts of Mirabilis jalapa Linn. (Nyctaginaceae) on cattle filarial parasite Setaria cervi

  • Uddin, Qamar;Parveen, N.;Khan, Nizam U.;Zaidi, SM Kashif R.;Singhal, KC.
    • Advances in Traditional Medicine
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    • v.3 no.4
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    • pp.180-186
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    • 2003
  • Effect of aqueous and alcoholic extracts of the roots of Mirabilis jalapa Linn. Four Oclock plant, on the spontaneous movements of both the whole worm and the nerve-muscle (n.m.) preparation of Setaria cervi and on the survival of microfilariae in vitro was studied. Alcoholic extract caused the inhibition of spontaneous movements of the whole worm and the n.m. preparation of S. cervi, whereas aqueous extract caused inhibition of spontaneous movements of the n.m. preparation. The initial stimulatory effect was not observed by aqueous and alcoholic extracts on n.m. preparation while effect of alcoholic extract on the whole worm was characterized by an increase in the amplitude of contractions followed by reversible paralysis. The concentrations required to inhibit the movements of the whole worm and n.m. preparation for alcoholic extract of root were $270\;{\mu}g/mL$ and $40\;{\mu}g/mL$, respectively whereas an aqueous extract caused inhibition of n.m. preparation at $30\;{\mu}g/mL$ suggesting a cuticular permeability barrier. Alcoholic extract of the roots of M. jalapa caused concentration related effect on the survival of microfilariae of S. cervi. The $LC_{50}$ and $LC_{90}$ for alcoholic extract as observed after 6 hrs. were found to be 10 ng/mL and 18 ng/mL., respectively.

Mental nerve paresthesia secondary to initiation of endodontic therapy: a case report

  • Andrabi, Syed Mukhtar-Un-Nisar;Alam, Sharique;Zia, Afaf;Khan, Masood Hasan;Kumar, Ashok
    • Restorative Dentistry and Endodontics
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    • v.39 no.3
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    • pp.215-219
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    • 2014
  • Whenever endodontic therapy is performed on mandibular posterior teeth, damage to the inferior alveolar nerve or any of its branches is possible. Acute periapical infection in mandibular posterior teeth may also sometimes disturb the normal functioning of the inferior alveolar nerve. The most common clinical manifestation of these insults is the paresthesia of the inferior alveolar nerve or mental nerve paresthesia. Paresthesia usually manifests as burning, prickling, tingling, numbness, itching or any deviation from normal sensation. Altered sensation and pain in the involved areas may interfere with speaking, eating, drinking, shaving, tooth brushing and other events of social interaction which will have a disturbing impact on the patient. Paresthesia can be short term, long term or even permanent. The duration of the paresthesia depends upon the extent of the nerve damage or persistence of the etiology. Permanent paresthesia is the result of nerve trunk laceration or actual total nerve damage. Paresthesia must be treated as soon as diagnosed to have better treatment outcomes. The present paper describes a case of mental nerve paresthesia arising after the start of the endodontic therapy in left mandibular first molar which was managed successfully by conservative treatment.