• Advances in Traditional Medicine
• /
• v.8 no.2
• /
• pp.192-195
• /
• 2008

The effect of aqueous and alcoholic extract of roots of Berberis aristata was studied on the spontaneous movements of the whole worm (w.w) preparation and nerve muscle (n.m) complex of cattle filarial parasite Setaria cervi and on the survival of microfilariae. Only aqueous extract could inhibit the spontaneous movements of S. cervi, characterized by initial stimulation followed by reversible paralysis. The concentration required to produce similar effect on n.m complex was less as compared to the w.w. The lethal concentration 50 and lethal concentration 90 for aqueous extract were 48 ng/ml and 65 ng/ml.

• Kyungpook Mathematical Journal
• /
• v.31 no.2
• /
• pp.207-217
• /
• 1991

• Parasites, Hosts and Diseases
• /
• v.52 no.6
• /
• pp.621-629
• /
• 2014

Malaria is one of the most widespread infectious diseases of tropical countries with an estimated 207 million cases globally. In India, there are endemic pockets of this disease, including Aligarh. Hundreds of Plasmodium falciparum and P. vivax cases with severe pathological conditions are recorded every year in this district. The aim of this study is to find out changes in liver enzymes and kidney markers. Specific diagnosis for P. falciparum and P. vivax was made by microscopic examination of Giemsa stained slides. Clinical symptoms were observed in both of these infections. Liver enzymes, such as AST, ALT, and ALP, and kidney function markers, such as creatinine and urea, were estimated by standard biochemical techniques. In Aligarh district, P. vivax, P. falciparum, and mixed infections were 64%, 34%, and 2%, respectively. In case of P. falciparum infection, the incidences of anemia, splenomegaly, renal failure, jaundice, and neurological sequelae were higher compared to those in P. vivax infection. Recrudescence and relapse rates were 18% and 20% in P. falciparum and P. vivax infections, respectively. Liver dysfunctions and renal failures were more common in P. falciparum patients, particularly in elderly patients. Artesunate derivatives must, therefore, be introduced for the treatment of P. falciparum as they resist to chloroquine as well as sulfadoxine-pyrimethamine combinations.

• Advances in Traditional Medicine
• /
• v.5 no.3
• /
• pp.240-245
• /
• 2005

The effect of aqueous and alcoholic extract of seeds of Nigella sativa (N. sativa) was studied on the spontaneous movements of the whole worm (w.w) preparation and nerve muscle (n.m) complex of Setaria cervi (S. cervi). Both the extracts caused inhibition of spontaneous movements of the w.w and n.m complex characterized by initial stimulation followed by irreversible paralysis, with the exception that aqueous extract produced a partially reversible paralysis of w.w preparation. Lesser concentration of both the extracts was required to inhibit the movements of n.m complex than the w.w. Suggesting a cuticular permeability barrier. The lethal concentration $50\;(LC_{50})$ and lethal concentration $90\;(LC_{90})$ were 30 and 55 ng/ml for aqueous and 45 and 60 ng/ml for alcoholic extracts respectively.

• Kyungpook Mathematical Journal
• /
• v.18 no.2
• /
• pp.223-232
• /
• 1978

• Kyungpook Mathematical Journal
• /
• v.18 no.2
• /
• pp.141-142
• /
• 1978

• Kyungpook Mathematical Journal
• /
• v.24 no.1
• /
• pp.45-50
• /
• 1984

• Kyungpook Mathematical Journal
• /
• v.21 no.2
• /
• pp.311-313
• /
• 1981

• Kyungpook Mathematical Journal
• /
• v.29 no.2
• /
• pp.125-131
• /
• 1989

• Kyungpook Mathematical Journal
• /
• v.20 no.1
• /
• pp.53-58
• /
• 1980