• 생물정신의학
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• 제4권2호
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• pp.225-233
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• 1997

The authors attempted to examine the allelic association between the A1 allele of Dopamine $D_2$ receptor and schizophrenia, alcoholism, drug addiction in Koreans. Schizophrenic patients(n=31), alcoholism(n=65), drug addiction(n=18) and controls(n=52) were examined by case-control study for distribution of the TaqI polymorphism of the dopamine $D_2$ receptor gene in Korean population to minimize the effect of racial differencies in gene frequencies. In schizophrenics, the numbers of schizophrenics with A1A1, A1A2, A2A2 were 9(29.0%), 15(48.4%) and 7(22.6%) respectively and in alcoholics with A1A1, A1A2, A2A2 were 14(21.5%), 36(55.4%) and 15(23.1%) respectively and in drug addiction with A1A1, A1A2, A2A2 were 2(11.1%), 10(55.6%) and 6(33.3%) respectively and in controls with A1A1, A1A2, A2A2 were 4(7.6%), 24(46.2%) and 24(46.2%) respectively. The prevalence of the A1 allele in schizophrenics, alcoholics, drug addiction and controls were 77%, 76.9%, 67% and 53.8% respectively. And the frequency of the A1 allele in schizophrenics, alcoholics, drug addiction and controls were 0.53, 0.49 0.39 and 0.31 respectively. There was significant difference in the frequency of the A1 allele between schizophrenics, alcoholics and controls. We also classified our alcoholic population. For classification by severity, we used the median MAST score 30 in our samples. There was also significant difference in the frequency of the A1 allele between less severe group(0.42) and more severe group(0.57). This data suggest that the A1 allele is associated with schizophrenia and alcoholism in Koreans. Furthermore the prevalence of the A1 allele increassed in more severely affected alcoholics. The authors conclude that our data support an allelic association between the A1 allele at dopamine $D_2$ receptor and schizophrenia, alcoholism. These results suggest the A1 allele of the $DRD_2$ gene is associated with a number of behavior disorders in which it may act as a modifying gene rather than as the primary etiological agent.

• 한국산학기술학회논문지
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• 제17권11호
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• pp.386-394
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• 2016

본 연구는 치료공동체에 거주하는 알코올 중독자의 회복을 측정하는 도구 CAS(Client Assesment Summary)의 한국어판의 타당도를 검증하여 일반 알코올 중독자의 회복 척도로 사용하기에 수용가능한지에 대한 적합성을 검증하는 것을 목표로 한다. 연구 대상자로 단주 중인 알코올 중독자 205명의 자료를 분석하였으며, 분석은 CAS 척도의 내용타당도, 신뢰도, 요인분석을 통한 구성타당도, 타 회복척도인 ARS, 단주기간, 단주 자기 효능감, 병식, 변화 동기 변수와의 관계 분석을 통해 기준타당도를 검증하는 분석을 시행하였다. 내용타당성 검증 후의 구성타당도 검증을 위한 요인분석 결과, CAS척도는 전체 12문항, 4개 요인으로 구성되었으며 전체 설명력은 76.26%, 공통성 0.6 이상, KMO 값 0.92로 구성타당도를 확인할 수 있었다. 내적일치도 계수는 .92로 신뢰도를 확인하였으며, ARS, 단주기간, 단주 자기효능감, 병식, 변화 동기 변인과의 상관관계로 기준타당도를 확인할 수 있었다. 이러한 검증 과정을 통하여 CAS척도가 치료공동체 뿐 아니라 일반 알코올 중독자에게 사용하기에도 타당한 척도임을 확인하였으며, 이상의 척도가 알코올 중독자의 회복을 평가하는데 학술적, 임상적으로 활용되어 궁극적으로 알코올 중독자의 회복에 기여하기를 기대한다.

• 동의신경정신과학회지
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• 제20권2호
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• pp.71-84
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• 2009

Objectives : This study was performed to assess the benefits of Alcoholics anonymous program for anxiety and depression of alcoholics. And we investigate Sasang constitution in Alcoholics Anonymous(A.A.) members to study relation between alcoholic and constitution. Methods : 21 members of A.A. groups in korea who agreed to the purpose of this study were selected. We evaluated anxiety by BAl, depression by BDI-II and sasang constitution by QSCCII+. Results : The research result is as follows. 1. Eighteens of 21 A.A. members are men and the rest are women. First alcohol drinking age(mean) is 15. Getting alcohol drunk age(mean) is 20.9. 2. The duration of alcohol drinking before A.A. participation(mean) is 20.2 years. The duration of giving up drinking after A.A. participation(mean) is 26.5 months. 3. A.A. program significantly reduced anxiety of A.A. members from 10.43${\pm}$1.37(mean${\pm}$S.E.)(light anxiety) to 6.86${\pm}$1.24(normal). 4. A.A. program significantly reduced depression of A.A. members from 4.14${\pm}$1.14(mean${\pm}$S.E)(normal) to 2.33${\pm}$0.75(normal) in the statistics, but it does not have the meaning clinically. 5. Sasang constitution classification result was Taeum group 10 people(47.6%), Soyang group 9 people(42.9%), Soeum group 2peopleC9.5%), Taeyang group 0 people(0%), Taeum group and Soyang group were relatively more than Soeum group. Conclusions : Participation in the A.A. program reduce anxiety and depression of A.A. members. This research provide data on positive effect of A.A. program and may prove that the self-help program(A.A.) can help to maintain long term sobriety and improve the quality of life of its members.

• 대한지역사회영양학회:학술대회논문집
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• 대한지역사회영양학회 1999년도 춘계학술대회초록집:노년기의 식사지침과 급식방향
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• pp.113-113
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• 1999

• 한국사회복지학
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• 제23권
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• pp.151-175
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• 1994

• 한국사회복지학회:학술대회논문집
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• 한국사회복지학회 1993년도 추계학술대회 자료집
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• pp.195-212
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• 1993

• 가정과삶의질연구
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• 제25권2호
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• pp.1-12
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• 2007

This is an investigative study to consider children's COA by parent's problem drinking and their psychological-social character by the COA. According to the results of this study, almost half of the children's COA, among those who have problem drinking parents, demonstrated high dangerous lever in the lower factors, such as emotional character, personnel relative character, and co-dependent character. Results of the inspection into the differences between the psyrhological-social characters, according to the danger lever of the children's COA, suggested the children's danger lever is higher, the self-efficiency and adaptable flexibility, which are the psychological-social characters, are lower, and there are no special differences in the social-support.

• International Journal of Advanced Culture Technology
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• 제7권3호
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• pp.103-110
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• 2019

The purpose of this study was to investigate the relationship between psychosocial factors, such as self-esteem, stress coping, and social support, and motivation for change in alcohol dependent inpatients. This study included 179 inpatients in the 7clinics for alcoholic in Chonbuk. For the analysis of the study questions, this study utilized the structural equation modeling. The results show that self-esteem was related to motivation for change with mediating role of problem-focused stress coping strategy in alcohol dependent inpatients. The study also reveal that self-esteem and social support was directly associated with the motivation for change. Based on the findings, the importance of programs to promote self-esteem and the involvement of family and acquaintances in the treatment process has been suggested.

• 한국동물학회:학술대회논문집
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• 한국동물학회 1998년도 한국생물과학협회 학술발표대회
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• pp.349.2-349
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• 1998

No Abstract, See Full Text

• 한국식품영양과학회지
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• 제27권6호
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• pp.1236-1243
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• 1998

The purpose of this study is to evaluate the nutritional status of protein and lipids in the patients with alcoholic liver disease, to find an effective way of dietary management for patients with alcoholic liver disease and to obtain the materials for nutritional education for alcoholics. The subjects consist of 80 patients with alcoholic liver cirrhosis(ALC) and 12 patients with alcoholic fatty liver(AFL). The control group included 57 alcoholics without liver disease(A), 32 patients with viral liver cir rhosis(VLC) and 194 normal(NL). Biochemical evaluation of nutritional status was performed by ana lyzing the profiles of protein and lipids in blood samples. The results are summarized as follows: 1) The frequency of subjects below the normal range of serum total protein was 26.3% in ALC, 16.7% in AFL and 3.5% in A. Serum albumin was lower in 41.3% of ALC. 2) The alcoholics without liver disease showed significantly higher level of serum triglycerides, total cholesterol and LDL cholesterol than the other groups. The alcoholic subjects had lower HDL cholesterol than normal subjects. Overall, the protein and lipids status of the alcoholic subjects in this study was evaluated to be very poor on the basis of biochemical assessments. The results suggest that alcohol abuse and poor dietary intake could cause malnutrition. An extensive nutritional education should be emphasized for the alcohol consuming population. High quality of protein and other dietary intakes from early stage of the disease may be effective in nutritional therapy for the patient with alcoholic liver disease.