• Investigative Magnetic Resonance Imaging
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• 제25권3호
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• pp.164-171
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• 2021

Purpose: Mild cognitive impairment (MCI) is a prodromal stage of Alzheimer's disease (AD). Brain atrophy in this disease spectrum begins in the medial temporal lobe structure, which can be recognized by magnetic resonance imaging. To overcome the unsatisfactory inter-observer reliability of visual evaluation, quantitative brain volumetry has been developed and widely investigated for the diagnosis of MCI and AD. The aim of this study was to assess the prediction accuracy of quantitative brain volumetry using a fully automated segmentation software package, NeuroQuant^®, for the diagnosis of MCI. Materials and Methods: A total of 418 subjects from the Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer's Disease cohort were included in our study. Each participant was allocated to either a cognitively normal old group (n = 285) or an MCI group (n = 133). Brain volumetric data were obtained from T1-weighted images using the NeuroQuant software package. Logistic regression and receiver operating characteristic (ROC) curve analyses were performed to investigate relevant brain regions and their prediction accuracies. Results: Multivariate logistic regression analysis revealed that normative percentiles of the hippocampus (P < 0.001), amygdala (P = 0.003), frontal lobe (P = 0.049), medial parietal lobe (P = 0.023), and third ventricle (P = 0.012) were independent predictive factors for MCI. In ROC analysis, normative percentiles of the hippocampus and amygdala showed fair accuracies in the diagnosis of MCI (area under the curve: 0.739 and 0.727, respectively). Conclusion: Normative percentiles of the hippocampus and amygdala provided by the fully automated segmentation software could be used for screening MCI with a reasonable post-processing time. This information might help us interpret structural MRI in patients with cognitive impairment.

• 자원리싸이클링
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• 제31권4호
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• pp.3-11
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• 2022

전기차 수요의 증가로 향후 폐차 혹은 배터리 노후화로 인한 폐배터리 배출량 급증이 예상됨에 따라 이에 대한 적정 관리가 시급한 실정이다. 기술개발 측면에서는 데이터 기반 진단 등 다양한 폐배터리 진단 및 관리 기술이 주목을 받고 있다. 또한 로봇기반 자동 해체 기술은 산업 현장에서의 Test 검증 및 향후 배터리 관련 데이터베이스와의 연동이 필요한 것으로 보인다. 특히 향후 폐배터리 순환과정에서의 효율화와 동시에 안전성/친환경성 제고를 위한 다양하고 선진적인 배터리 진단 및 평가기법 개발 및 보급이 중요하다. 또한 리튬 관련 화학물질 배출이동에 대한 데이터베이스화와 배터리 연소시 가스유출위험 및 소방안전에 관한 평가 및 대처가 중요할 것으로 보인다. 더 나아가 데이터 기반 진단/분류/해체 과정을 재활용/최종폐기와 연계된 다양한 관점에서의 폐배터리 전주기 관리 최적화 등에 향후 더 많은 연구개발이 필요하다고 판단된다. 그리고 일련의 데이터는 차후 배터리 생산 시 환경적 부담을 감소시키고 재이용/재활용이 원활하도록 청정설계 및 제조에 기여해야 한다. 또한 이러한 최적화는 전기차 배터리의 향후 기술 및 시장 변동을 감안하여 추진되어야 한다.

• 전자공학회논문지CI
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• 제46권6호
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• pp.18-26
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• 2009

본 논문에서는 심전도 기반의 u헬스케어시스템을 위한 다용도 신호추출 방법을 제안한다. 심전도 기반의 u헬스케어시스템 구현을 위해서는 심장질환 진단을 위한 QRS파형의 추출기술이 필수적이다. 또한, 보안성 및 편의성을 위하여 u헬스케어시스템에서 ECG신호와 같은 생체신호에서 직접 사용자의 신원을 확인할 수 있는 생체인식기능을 보유하고 있다면 매우 유용하다. 이를 위해서 본 논문에서는, 리드II 파형으로부터 QRS파형을 추출하고, 또한 상대적으로 노화 및 질환에 따른 변동에 강건한 리드III 파형으로부터 생체인식을 위한 신호추출법을 제안한다. 리드II 파형으로부터 QRS신호추출성능을 검증하기 위해 MIT-BIH 데이터베이스의 심전도신호가 사용되었고 99.36%의 정확도 및 99.68%의 민감도성능을 보였다. 또한 생체인식용 신호추출성능평가를 위해서는 다양한 측정환경을 고려하기 위해 음주, 흡연 및 운동 직후 리드III파형이 측정되었고 99.92%의 정확도 및 99.97%의 민감도 성능을 보였다.

• 전기학회논문지
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• 제60권8호
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• pp.1632-1638
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• 2011

Electric cables are one of the most important components in a nuclear power plant since they provide the power needed to operate electrical equipment. Despite their importance, cables typically receive little attention since they are considered passive, long-lived components that have been very reliable over the years when subjected to the environmental conditions for which they were designed. The operating experience reveals that a defect of the insulator or poor construction causes the initial failure of cable. However, the number of cable failures increase with plant aging, and these cable failures are occurring within the plants' 40-year licensed period. These cable failures have resulted in plant transients, shutdown, loss of safety functions or redundancy, entries into limiting conditions for operation, and challenges for plant operators. Therefore, diagnosis of MV cable installed in NPPs has become one of the most urgent issues in recent years. In accordance with PSR, condition maintenance for cables is also continuously required. Recently, HFPD tests have been widely performed to diagnose cable in the transmission and distribution cable system. However, on-line HFPD wasn't used in the NPPs because of the danger of plant shutdown, measurement sensitivity and application problems, etc. In this paper, HFPD measurement with portable device was performed to evaluate the integrity of the 4.16kV & 13.8kV cable lines. The test results show that HFPD is highly attractive to the diagnosis of MV cables in NPP by high detection sensitivity on-site.

• 한국융합학회논문지
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• 제11권2호
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• pp.75-83
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• 2020

본 연구는 손상으로 입원한 노인을 전기 노인과 후기 노인으로 구분하여 전·후기 노인의 일반적 특성, 주진단명 특성, 손상관련 특성 및 운수사고 유형의 차이를 파악하고자 시행되었다. 질병관리본부의 퇴원손상심층조사 원시자료를 활용하였으며, 복합표본 교차분석(카이제곱 검정)과 복합표본 일반선형모형(t검정)을 사용하여 분석하였다. 분석결과, 일반적 특성은 전기 노인은 건강보험이 높은 반면, 후기 노인은 의료급여가 높게 나타났다. 주진단명 특성은 전기 노인은 뇌 손상이 높았고 후기 노인은 대퇴골 골절이 월등히 높았다. 손상관련 특성은 전·후기 노인 모두 낙상이 가장 높았고, 후기 노인에서 손상발생장소로 가정이나 주거지가, 일상생활 중, 의도성 자해가 높았다. 운수사고 유형은 전기 노인은 승용차 운전자가 높았고, 후기 노인은 보행자 사고가 높았다. 이러한 연구결과에 따라 후기 노인은 전기 노인에 비해 더 많은 의료서비스, 경제적 지원, 주거지 중심의 낙상 예방 대책 및 자살 등 의도적 손상 예방을 위한 사회 심리적 전략이 요구되며, 후기 노인의 보행자 교통사고 예방을 위한 교육 및 도로 등 안전한 보행 환경을 위한 노력이 요구된다.

• 디지털융복합연구
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• 제18권5호
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• pp.305-315
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• 2020

치매(dementia)는 고령화와 함께 유병 인구가 지속적으로 늘어남에 따라 사회적 부담이 가중되고 있는 만큼 조기 진단의 필요성이 강조되고 있다. 이에 치매 예방 및 치매조기진단을 위한 검진을 실시하고 있으나 현재의 검사로는 치매조기진단이 사실상 불가능한 것으로 나타났다. 이를 해결하기 위해서는 의료 빅데이터의 통합 및 각각의 지표를 분석한 결과를 융합·패턴화 시키는 것이 필수적이다. 이에 국회에서는 빅데이터 활용 활성화를 위해 빅데이터의 개방과 공유를 골자로 하는 데이터 3법이 통과되었으나 보다 안전한 활용을 위해 후속 입법의 필요성이 제기되고 있다. 본 연구에서는 선행 연구 고찰을 통해 국외 정책을 파악하고 시사점을 도출, 의료 빅데이터의 안전한 활용을 위해 데이터 3법에 맞춘 구체적 시행령 제정 및 수집 및 폐기까지의 단계별 보안책 수립, 그리고 국가 차원의 거버넌스 구축을 제안하였다.

• 한국보건간호학회지
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• 제17권1호
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• pp.47-57
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• 2003

The purpose of this study was to investigate health status and health promoting behaviors of female elderly, and their needs for health-related services in an urban-rural combined city. The data were collected from the subjects registered in senior welfare center and senior citizens' clubs. A total of 119 women were participated in the survey. The results of the study are as follows; 1. The subjects perceived their health status relatively unhealthy. Their health promotion behavior score was 10.82 (range 0-17), and more than $60\%$ of them performed well in smoking and drinking control, regular meal. taking breakfast, and maintaining good relationship with others. 2. The most needed service was health screening followed by health risk assessment, disease diagnosis and treatment. 3. The most demanded education was on dementia prevention, followed by exercise, balanced diet, and maintenance of memorial and mental capability. 4. As the health interest and the health responsibility increased, the need for health service increased as well. Likewise, the health education needs increased as the health interest, health responsibility, and health promotion behavior increased. The results show that the health promotion programs for female elderly need to be focused, primarily, on health screening, health risk assessment, medical services for disease diagnosis and treatment, and health consulting and education. And health consulting and education programs should be designed to promote health interest and health responsibility of female elderly, change positively their attitude to aging, and include education on dementia prevention, exercise and nutrition management. Recommendations are discussed.

• 한국전기전자재료학회논문지
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• 제29권10호
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• pp.635-640
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• 2016

This paper dealt with the deterioration characteristics and an on-line diagnosis equipment for SPDs (surge protective devices). An accelerated aging test was carried out using a $8/20{\mu}s$ standard lightning impulse current to analyze the changes of electrical characteristics and to propose the diagnostic parameters and the criterion for deterioration of ZnO varistor which is the core component of SPDs. Based on the experimental results, an on-line diagnosis equipment for SPD was fabricated, which can measure the total leakage current, reference and clamping voltage. The leakage current measurement circuit was designed using a low-noise amplifier and a clamp type ZCT. A linear controller, the leakage current measurement part and a HVDC were used in the measurement of reference voltage. The measurement circuit of clamping voltage consisted of a surge generator and a coupling circuit. In a calibration process, measurement error of the prototype equipment was less than 3%.

• 전기학회논문지
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• 제57권9호
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• pp.1606-1611
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• 2008

Recently, The diagnosis techniques of electric facilities are developed on live line. This paper describes the discharge characteristics of polymer insulator(EPDM A type). Keeping the facilities in good working order, the goal of this paper will provide the information to enable user to easily judge conditions of facilities on the spot. The performance of polymer insulator is assessed from the KS C IEC 60270 and CEA LWIWG-01(96)(Tracking Wheel Test). As the results, UV generation patterns of polymer insulator grow like a jellyfish shape follow the ramping voltage. Discharging UVs are detected at about 31.25% of breakdown voltage. Just then, dimension of UV image is about $0.84cm^{2}$. The dimension of max. UV image is about $297.4cm^{2}$ at $160kV(V_{bd})$. The position of UV generation due to surface discharge of polymer insulator is the center of insulator in the early, then moved the ground side and the last, UV image moved through the junction part of source side. Surface of aged polymer insulator is cracked and faded due to arc. UV absorption spectrum of polymer insulator are appeared the C-H bond of scissoring vib. at $1014cm^{-1}$ and C=O bond of recombination structure. Also, recombined UV absorption peak such as C-H, N-H, and O-H is detected at the $3321cm^{-1}$. Through the paper, there are inspection data which are the relations between surface discharge of polymer insulator and UV detecting image.

• Journal of the Optical Society of Korea
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• 제18권1호
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• pp.55-59
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• 2014

Sarcopenia, or reduced muscle mass and volume, is due to various factors such as senile change, neuronal degeneration, drug, malignancy, and sepsis. Sarcopenia with the aging process has been evidenced by the decline in muscle mass by 0.5 to 1% per year with 3-5% reduction in muscle strength for 10 years between the ages of 40 and 50, and a 1-2% of decline of mass every year in people aged 60-70. Therefore, early diagnosis and understanding the mechanism of sarcopenia are crucial in the prevention of muscle loss. However, it is still difficult to image changes of muscle microstructure due to a lack of techniques. In this study, we developed an animal model using denervated rats to induce a rapid atrophy in the tibialis anterior (TA) and imaged its structural changes using optical coherence tomography (OCT) along with histologic and ultrasound analyses. Ultrasound showed changes of overall muscle size. Histology revealed that the atrophic TA muscle displayed an increased size variability of muscle fiber and inflammatory changes. Three dimensional OCT imaged the changes of perimysial grid and muscle fiber structure in real time without sacrifice. These observed advantages of multimodal imaging using OCT and ultrasound would provide clinical benefits in the diagnosis of sarcopenia.