• 통합자연과학논문집
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• 제16권3호
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• pp.75-80
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• 2023

Bipolar disorder is a mental illness characterized by extreme mood and behavioral swings, such as highs of euphoria and lows of depression. It is a socially significant disorder in which people with the disorder experience intense mood swings and, for those with severe bipolar disorder, it is even difficult leading a normal life. High stress levels in people with mental illness can lead to neuroendocrine disruption, and it is strongly linked to aging. When the neuroendocrine system becomes vulnerable to these mental illnesses and stress, it is likely to accelerate aging. And it's the epigenetic clock that can measure the extent of this accelerated aging. The Epi clock, a pan tissue clock, measures aging through DNA methylation, and the degree of methylation is modified and changed by environmental conditions in the body. Therefore we wanted to check the changes in the epigenetic age of the patients with bipolar disorder. While we found no significant differences in epigenetic age, we did confirm the possibility that people with bipolar disorder have different methylation than normal people. We also found that the EPIC array data fit better on the Epi clock than on the Horvath clock with age-accelerated data from normal people.

• 보건교육건강증진학회지
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• 제11권1호
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• pp.70-84
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• 1994

On the basis of the study intended to research by cross-sectional study keeped pace with semi-longitudinal study the growth accelerating phenomena that MGA(Maximum Growth Age) in teenager's body height. The duration of study is from Oct. 1st. 1991 to September 30 1992 and the data are analysed through computer. The body height and MGA of Koreans who had been for during the period from 1898 to 1973 proved transition of the growth accelerating phenomena by research data reported between 1913 and 1990. The results are as follows: 1. Maximum Growth Age The MGA's in body height of male are respectively the age 15.024 in 1913, 14.28 in 1940, 13.65 in 1959, 13.86 in 1967, 12.52 in 1983, 11.39 in 1987, 12.36 in 1990, while those of female are the age of 12.0 in 1940, 12.36 in 1959, 10.45 in 1969, 11.15 in 1985, 10.27 in 1988, 10.23 in 1990 ; these data show that the MGA of the Korean has been getting younger. 2. The correlation of the MGA's in body height are as below ; Male ; r = -0.448(p<0.01) Female ; r = -0.404(p<0.05) 3. The equation of linear regression of MGA's in body height are as below ; Male ; Y(MGA) = -0.0316X(the year)+75.297 Female ; Y(MGA) = -0.035X(the year)+79.986 4. The MGA's in body height are shown in Table 3. 5. From the transition of the growth accelerating phenomena, we can compute the fact that the MGA's has been getting younger by 0.3 year per 10 years. 6. The future growth accelerating phenomena in body height, the MGA's of male are respectively the age 12.25 in 1995, 12.09 in 2000, 11.94 in 2005, 11.78 in 2010, while those of female are the age of 10.16 in 1995, 9.98 in 2000, 9.81 in 2005, 9.64 in 2010, these data show that the MGA of female are more younger than that of male.

• 한국건설순환자원학회논문집
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• 제7권4호
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• pp.121-127
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• 2012

본 연구에서는 플라이애시를 치환한 시멘트 모르터의 양생온도에 따른 강도증진을 검토하기 위하여 등가재령방법에 의한 강도증진해석을 실시하였다. 플라이애시를 30% 치환한 시멘트모르터의 겉보기활성화에너지를 ASTM C 1074 방법에 의하여 산정한 결과 34.75KJ/mol로 산정되었고, 이를 토대로 Plowman 모델과 Gompertz 모델을 이용하여 해석한 결과 해석치가 측정치를 양호하게 추정함을 알 수 있었고 특히 Gompertz 모델식이 보다 양호한 추정 정밀도를 갖는 것으로 확인되었다.

• 대한간호학회지
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• 제41권5호
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• pp.613-622
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• 2011

Purposes: Study purpose were to describe growth patterns of premature infants in weight, length and head circumference from birth to 40th week of corrected ages (CA) and to explore factors affecting patterns. Methods: A longitudinal descriptive study was conducted with 267 premature infants. They were categorized into 2 groups; GA group with measurements at birth and the CA group with measurements at CA, which was categorized into 3 groups (group 1-3) by WHO guideline for gestational age (GA) at birth. Results: GA group presented greater measures in all than CA group at same week of life. Among CA groups, group 3 showed the highest measurements, up to 37 weeks of life, though this disappeared at 38-40 weeks. Reversely, group 1 revealed the highest growth rates in all measures, followed by group 2 and group 3. Significant interaction was observed in all measures between week of life and any type of groups. Conclusions: Higher measures in GA group, as well group 3 among CA groups, supported the superiority of intra-uterine environment overriding quality of regimen from NICU. Regardless of growth acceleration, smaller infants remain smaller, indicating that intra-uterine thrifty phenotype may continue at least up to the 40th week of CA.

• 천문학회지
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• 제44권2호
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• pp.49-58
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• 2011

We calculate the energy spectra of cosmic ray (CR) protons and electrons at a plane shock with quasi-parallel magnetic fields, using time-dependent, diffusive shock acceleration (DSA) simulations, including energy losses via synchrotron emission and Inverse Compton (IC) scattering. A thermal leakage injection model and a Bohm type diffusion coefficient are adopted. The electron spectrum at the shock becomes steady after the DSA energy gains balance the synchrotron/IC losses, and it cuts off at the equilibrium momentum $p_{eq}$. In the postshock region the cutoff momentum of the electron spectrum decreases with the distance from the shock due to the energy losses and the thickness of the spatial distribution of electrons scales as $p^{-1}$. Thus the slope of the downstream integrated spectrum steepens by one power of p for $p_{br}$ < p < $p_{eq}$, where the break momentum decreases with the shock age as $p_{br}\;{\infty}\;t^{-1}$. In a CR modified shock, both the proton and electron spectrum exhibit a concave curvature and deviate from the canonical test-particle power-law, and the upstream integrated electron spectrum could dominate over the downstream integrated spectrum near the cutoff momentum. Thus the spectral shape near the cutoff of X-ray synchrotron emission could reveal a signature of nonlinear DSA.

• 한국수학교육학회지시리즈D:수학교육연구
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• 제12권4호
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• pp.283-291
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• 2008

The extension to a wide population of secondary education in many advanced countries seems to have led to a weakening of the mathematics curriculum. In response, many students have been classified as "gifted" so that they can access a stronger program. Apart from the difficulties that might arise in actually determining which students are gifted (Is it always clear what the term means?), there are dangers inherent in programs that might be devised even for those that are truly talented. Sometimes students are moved ahead to more advanced mathematics. Elementary students might be taught algebra or even subjects like trigonometry and vectors, and secondary students might be taught calculus, differential equations and linear algebra. It is my experience over thirty-five years of contact with bright students that acceleration to higher level mathematics is often not a good idea. In this paper, I will articulate some of the factors that have led me to this opinion and suggest alternatives. First, I would like to emphasize that in matters of education, almost every statement that can be made to admit counterexamples; my opinion on acceleration is no exception. Occasionally, a young Gauss or Euler walks in the door, and one has no choice but to offer the maximum encouragement and allow the student to go to the limit of his capabilities. A young genius can demonstrate an incredible amount of mathematical insight, maturity and mastery of technique. A classical example is probably the teen-age Euler, who in the 1720s was allowed regular audiences with Jean Bernoulli, the foremost mathematician of his day.

• 한국해양공학회지
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• 제25권3호
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• pp.40-46
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• 2011

This paper describes the effects of fly ash replacement on the sulfate resistance of antiwashout underwater concrete which was replaced cement by fly ash from 0% to 50%. and the experimental works were performed on sulfate acceleration test of 5%$Na_2SO_4$ solution to find out the variance of length and weight of specimens. The experimental result shows that the length of specimens of antiwashout underwater concrete age at 180day was highly increased compare with normal concrete by acceleration test. but the mixture which was replaced 50% of fly ash shows reduction of the expansion, weight various, compare with normal concrete specimen. accordingly by using fly ash as admixture in antiwashout underwater concrete in sea environment, it will makes more durable for the attacks of sulfate by sea water.

• Earthquakes and Structures
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• 제22권3호
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• pp.277-287
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• 2022

The ancient underground cities are a collection of self-supporting spaces that have been manually excavated in the soil or rock in the past. Because these structures have a very high cultural value due to their age, the study of their stability under the influence of natural hazards, such as earthquakes, is very important. In this research, while introducing the underground city of Ouyi Nushabad located in the center of Iran as one of the largest man-made underground cities of the old world, the analysis of dynamic stability is performed. For this purpose, the dynamic stress-displacement analysis has been performed through numerical modeling using the finite element software PLAXIS. At this stage, by simulating the Khorgo earthquake as one of the large-scale earthquakes that occurred in Iran, with a magnitude of 6.9 on the Richter scale, dynamic analysis by time history method has been performed on three selected sections of underground spaces. This study shows that the maximum amount of horizontal and vertical dynamic displacement is 12.9 cm and 17.7 cm, respectively, which was obtained in section 2. The comparison of the results shows that by increasing the cross-sectional area of the excavation, especially the distance between the roof and the floor, in addition to increasing the amount of horizontal and vertical dynamic displacement, the obtained maximum acceleration is intensified compared to the mapping acceleration applied to the model floor. Therefore, preventive actions should be taken to stabilize the excavations in order to prevent damage caused by a possible earthquake.

• Journal of Biosystems Engineering
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• 제27권5호
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• pp.391-398
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• 2002

During handling unitized products, they are subjected to a variety of environmental hazards. Shock and vibration hazards are generally considered the most damaging of the environmental hazards on a product and it may encounter while passing through the distribution environment. A major cause of shock damage to products is drops during manual handling. The increasing use of unitization of pallets has been resulted in a reduction of the shock hazards. This has caused an increasing interest in research focused on vibration caused dam age. Damage to the product by the vibration most often occurs when a product or a product component has a natural frequency that falls within the range of the forcing frequencies of the particular mode of transportation being used. Transportation vibration is also a major cause of fruit and vegetable quality loss due to mechanical damage. This study was conducted to determine the vibration characteristics of the corrugated fiberboard bones for packages of pears, and to investigate the degree of vibration injury of the pears in the boxes during the simulated transportation environment. The vibration tests were performed on an electrohydraulic vibration exciter. The input acceleration to exciter was fixed at 0.25 G for a single container resonance test and 0.5 G for the vertical stacked container over the frequency range from 3 to 100 Hz. Function generator (HP-33120A) was connected by wire to the vibration exciter for controlling the input acceleration at a continuous logarithmic sweep rate of 1.0 octave per min. The peak frequency and acceleration on the single box test were 22.02 Hz, 1.5425 G respectively, and these values on the vertical stacked boxes were observed from the bottom box 19.02, 18.14, 16.62 and 15.40 Hz and 2.2987, 3.7654. 5.6087, and 7.9582 G, respectively. The pear in the bottom box had a slightly higher damage level than the fruit packed in the other stacked boxes. It is desirable that the package and transportation system has to be so designed that 15∼20 Hz frequency will not occur during the transportation environment.

• 천문학회지
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• 제48권2호
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• pp.155-164
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• 2015

In Kang (2015) we calculated the acceleration of cosmic-ray electrons at weak spherical shocks that are expected to form in the cluster outskirts, and estimated the diffuse synchrotron radiation emitted by those electrons. There we demonstrated that, at decelerating spherical shocks, the volume integrated spectra of both electrons and radiation deviate significantly from the test-particle power-laws predicted for constant planar shocks, because the shock compression ratio and the flux of inject electrons decrease in time. In this study, we consider spherical blast waves propagating through a constant density core surrounded by an isothermal halo with ρ ∝ r⁻ⁿ in order to explore how the deceleration of the shock affects the radio emission from accelerated electrons. The surface brightness profile and the volumeintegrated radio spectrum of the model shocks are calculated by assuming a ribbon-like shock surface on a spherical shell and the associated downstream region of relativistic electrons. If the postshock magnetic field strength is about 0.7 or 7 µG, at the shock age of ∼ 50 Myr, the volume-integrated radio spectrum steepens gradually with the spectral index from α_inj to α_inj + 0.5 over 0.1–10 GHz, where α_inj is the injection index at the shock position expected from the diffusive shock acceleration theory. Such gradual steepening could explain the curved radio spectrum of the radio relic in cluster A2266, which was interpreted as a broken power-law by Trasatti et al. (2015), if the relic shock is young enough so that the break frequency is around 1 GHz.