Mahmoudi, Touraj;Karimi, Khatoon;Arkani, Maral;Farahani, Hamid;Nobakht, Hossein;Dabiri, Reza;Asadi, Asadollah;Zali, Mohammad Reza
Asian Pacific Journal of Cancer Prevention
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v.15
no.15
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pp.6035-6039
/
2014
Background: Substantial evidence from epidemiological studies has suggested that increased levels of calcium may play a protective role against colorectal cancer (CRC). Given the vital role of calcium sensing receptor (CaSR) and parathyroid hormone (PTH) in the maintenance of calcium homeostasis, we explored whether the rs1801725 (A986S) variant located in exon 7 of the CaSR gene and the rs6256 variant located in exon 3 of PTH gene might be associated with CRC risk. Materials and Methods: In this study 860 subjects including 350 cases with CRC and 510 controls were enrolled and genotyped using PCR-RFLP methods. Results: We observed no significant difference in genotype or allele frequencies between the cases with CRC and controls for both CaSR and PTH genes either before or after adjustment for confounding factors including age, BMI, sex, smoking status, and family history of CRC. Furthermore, no evidence for effect modification of any association of rs1801725 and rs6256 variants and CRC by BMI, sex, or tumor site was observed. In addition, there was no significant difference in genotype and allele frequencies between the normal weight (BMI < $25kg/m^2$) cases and overweight/obese (BMI ${\geq}25kg/m^2$) cases for the two SNPs. Conclusions: These data indicated that the CaSR gene A986S variant is not a genetic contributor to CRC risk in the Iranian population. Furthermore, our results suggest for the first time that PTH gene variant does not affect CRC risk. Nonetheless, further studies with larger sample size are needed to validate these findings.
Journal of Korean Library and Information Science Society
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v.46
no.2
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pp.337-366
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2015
This study had begun about the conflict between a lack of social adjustment and integration program for resident foreigners in Korea and a duplication of multicultural service in a specific area. This study was implemented through literature review and interview for analyses of the current status and problems of multicultural policy, subdivided into 3-stages model to reach the multiculturalism as multicultural policy process. The first stage suggested the unification of a channel for establishing a policies, reinforcing the functions of government ministries and the cooperation between the branches of the government. The second stage attempted to build the multicutural institutes network in a specific area unit, considering of the geographical and administrative environments. The third stage focused on the activities of individual organizations and proposed collaboration with library, school, support center for multi-cultural families, social service center, sport center, community center, and cultural facility. Additionally, 3-stages model emphasized on civic organization's role. This study was offered a meta-platform leaded by library community for sharing the information about planning and managing of multicutural programs and also mentioned significances for formulating multicutural policies. As a result, this study was presented and specified the 3-stages model to reach the multiculturalism, and verified the various considerations which have influenced the refinements of the multicultural policies as the demographic and geographical characteristics.
Canada became the first OECD/DAC member state that legislated the ODA Accountability Act in 2008, which prescribe Canada ODA policies to meet the guidelines and norms of international human rights while other OECD/DAC member states was just emphasizing the importance of abiding by the international human rights norms. Paying attention to the Canadian case, this article critically examines under what structural environments and process this Act was passed. This article argues that the legislation of the ODA Accountability Act is closely related with Canada's international position as middle power and diplomatic strategies. Bring up the human security issues as a niche market, Canada demonstrates the characteristics of middle power state by emphasizing human rights agenda as new foreign policy strategies. Reflecting on the negative outcomes from neoliberal aid policy of structural adjustment and promoting the new aid norms in post cold war era would also help foster the enabling environment for the value-oriented aid policies and enactment of the Accountability Act. Civil society organizations were also playing catalyst role in constructing Canada's state identity of human rights defender.
The purpose of this study was to examine the effect of vision and hearing limitation on the onset of disability among Korean elderly with the consideration of social participation and depression. Study population consisted of 2,670 people aged 65 and above who participated in both the 1st(2006) and 2nd(2008) wave of the Korean Longitudinal Study of Aging(KLoSA), and also reported no ADL or IADL disability in 2006. As the results, first, it found that vision and hearing limitation, social participation, and depression were significant risk factors for the onset of IADL disability in unadjusted analysis. After multivariable adjustment, however, only vision limitation showed significant association with the onset of IADL disability. Second, in the logistic analysis with four categorized variables(vision/hearing limitation + social participation, vision/hearing limitation + depression), the elderly who had vision or hearing limitation had a significantly 1.7 times higher odds ratio for disability onset if they also had low social participation compared with those who had no vision or hearing limitation, and high social participation. Whereas, depression was not significantly associated with the relationship between vision or hearing limitation, and disability onset. The study suggests that the intervention program developed to prevent social isolation of older people with vision or hearing limitation, may be helpful to reduce and postpone the risk of disability onset as well as early detection and treatment of vision or hearing problems.
Journal of the Korean BIBLIA Society for library and Information Science
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v.30
no.1
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pp.5-27
/
2019
This study analyzed the effects of comic book reading program on Korean proficiency and acculturation of youth with immigration background, by conducting a six-month reading program with five teenagers with immigration background. Ten comic books were selected from published by School Library Journal, based on the themes - that are related to the lives of youth with immigration background - and interests of participating teens. According to the literacy skills test conducted before and after the reading program, the participating teens' Korean proficiency has generally improved, particularly in the areas of interpretation and vocabulary. In terms of writing, grammatically incorrect sentences, phrases, and expressions have declined. Most participants showed stable adjustment to Korean culture, but one participant who felt still insecure of her ethnic identity deeply empathized with one of the characters of the books, and shared the difficulties of living as an outsider of a society. The participants of this research learned or rediscovered the joy of reading through this comic book reading program; at the end of the program, many of them expanded their interest in reading novels, books without any illustrations.
Journal of the Institute of Electronics Engineers of Korea SD
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v.47
no.9
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pp.14-23
/
2010
This paper reports the fabrication of a DVB-T/H System in Package (SiP) that is able to receive and process the DVB-T/H signal. The DVB-T/H is the European telecommunication standard for Digital Video Broadcasting (DVB). An IC-embedded Printed Circuit Board (PCB) process, interpose a chip between PCB layers, has applied to the DVB-T/H SiP. The chip inserted in DVB-T/H SiP is the System on Chip (SoC) for mobile TV. It is comprised of a RF block for DVB-T/H RF signal and a digital block to convert received signal to digital signal for an application processor. To operate the DVB-T/H IC, a 3MHz DC-DC converter and LDO are on the DVB-T/H SiP. And a 38.4MHz crystal is used as a clock source. The fabricated DVB-T/H SiP form 4 layers which size is $8mm{\times}8mm$. The DVB-T/H IC is located between 2nd and 3rd layer. According to the result of simulation, the RF signal sensitivity is improved since the layout modification of the ground plane and via. And we confirmed the adjustment of LC value on power transmission is necessary to turn down the noise level in a SiP. Although the size of a DVB-T/H SiP is decreased over 70% than reference module, the power consumption and efficiency is on a par with reference module. The average power consumption is 297mW and the efficiency is 87%. But, the RF signal sensitivity is declined by average 3.8dB. This is caused by the decrease of the RF signal sensitivity which is 2.8dB, because of the noise from the DC-DC converter.
Journal of agricultural medicine and community health
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v.28
no.2
/
pp.135-154
/
2003
Objectives: This study was performed to investigate attitude and participation status on district health planning of officials in Health Centers. Methods: The data collected by self-administered questionnaire survey of 674 officials of Health Centers and the data on district health planning of 28 Health Centers in Gyeongsangbuk-do and Daegu metropolitan city were analyzed. Results: Only 13.6% of officials of Health Centers responded that they had read 'the second district health planning paper' thoroughly and 12.5% of officials of Health Centers replied that they had known contents of 'the second district health planning paper' fully. 56.9% of officials of Health Centers didn't have 'the second district health planning paper'. Thirty five point four percent(35.4%) of health center officials replied that the mayor's or county executive's concern about the district health planning was high, 22.4% in councilors, 77.8% in Health Center chiefs, 44.9% in Health Center officials, 43.9% in him or her. Among respondents, 58.6% of Health Center officials replied that district health planning was necessary and 38.0% of subjects replied that the degree of utilization of district health planning was high. About thirty seven percent(36.9%) of respondents participated in making out 'the second district health planning paper' and 49.6% in 'the third district health planning paper'. Health Center officials replied that the most serious problem of district health planning was 'lack of budget and personnels'(39.8%), 'lack of concern for district health planning'(21.4%) and the most important thing to improve district health planning was 'establishing department for health planning', 'adjustment of establishment time for district health planning'. Conclusions: In order to establish effective district health planning, it would be necessary to secure budget and personnels, to promote the county executive's concern and Health Center officials' concern about the district health planning, to establish department for health planning, and to adjust establishment time for district health planning.
This study examined the factors that influence the smartphone user's decision to accept the personalized mobile advertisement. As a theoretical basis, we applied the privacy calculus model (PCM) that illustrates how consumers are engaged in a dynamic adjustment process in which privacy risks are weighted against benefits of information disclosure. In particular, we investigated how smartphone users make a risk-benefit assessment under which personalized service as benefit-side factor and information privacy risks as a risk-side factor accompanying their acceptance of advertisements. Further, we extend the current PCM by considering advertisement fatigue as a new factor that may influence the user's acceptance. The research model with five (5) hypotheses was tested using data gathered from 215 respondents through a quasi-experimental survey method. During the survey, each participant was asked to navigate the website where the experimental simulation of a mobile advertisement service was provided. The results showed that three (3) out of five (5) hypotheses were supported. First, we found that the intention to accept advertisements is positively and significantly influenced by the perceived value of personalization. Second, perceived advertisement fatigue was also found to be a strong predictor of the intention to accept advertisements. However, we did not find any evidence of direct influence of privacy risks. Finally, we found that the significant moderating effect between the perceived value of personalization and advertisement fatigue. This suggests that the firms should provide effective tailored advertisement that can increase the perceived value of personalization to mitigate the negative impacts of advertisement fatigue.
Journal of the Korean Academy of Child and Adolescent Psychiatry
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v.13
no.1
/
pp.93-103
/
2002
The aim of this study is to examine the diagnostic profiles and related clinical variables of children with attention and hyperactivity in psychiatric outpatient clinic. Seventy one children with age range of 5 to 14 were diagnosed by DSM-IV, and assessment battery including KEDI-WISC, KPI-C, ADS(ADHD Diagnostic System) were completed. The subjects were divided into 3 diagnostic groups:ADHD only(n=17), ADHD comorbid(n=27), Other diagnosis(n=27). The results were as follows:In ADHD comorbid group, tic disorder, developmental language disorder, borderline intellectual function, oppositional defiant/conduct disorder, and learning disorder were combined in descending order. Other diagnosis group consisted of tic disorder, borderline intellectual function, depression/anxiety, oppositional defiant/conduct disorder, and others. There were significant differences in IQ, PIQ, and VIQ among the three groups, and ADHD only group showed higher scores of IQ and VIQ than ADHD comorbid group. On the KPI-C, there were no significant differences in all subscales among the three groups. On the visual ADS, omission error and sensitivity showed significant differences among the three groups, and ADHD comorbid group represented higher omission error and lower sensitivity than other diagnostic group. The findings indicated that the inattention and hyperactivity symptoms could be diagnosed into diverse psychiatric disorders in child psychiatry, and ADHD children with comorbidity will show more problems in academic performance and school adjustment.
Journal of the Korea Academia-Industrial cooperation Society
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v.19
no.3
/
pp.630-637
/
2018
Harmony search (HS) is a recently developed metaheuristic optimization algorithm. HS is inspired by the process of musical improvisation and repeatedly searches for the optimal solution using three operations: random selection, memory recall (or harmony memory consideration), and pitch adjustment. HS has been applied by many researchers in various fields. The increasing complexity of real-world optimization problems has created enormous challenges for the current technique, and improved techniques of optimization algorithms and HS are required. We propose an improved clustering harmony search (ICHS) that uses a clustering technique to group solutions in harmony memory based on their objective function values. The proposed ICHS performs modified harmony memory consideration in which decision variables of solutions in a high-ranked cluster have higher probability of being selected than those in a low-ranked cluster. The ICHS is demonstrated in various optimization problems, including mathematical benchmark functions and water distribution system pipe design problems. The results show that the proposed ICHS outperforms other improved versions of HS.
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