• Title/Summary/Keyword: Adhesion control

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Long-term Colchicine Prophylaxis on Operative Adhesion Formation in Embryo Transfer Donor Ewes and the Cytogenetic Evalution of Therapy (Embryo Transfer Donor Ewe에 생기는 수술상의 Adhesion 형성에 대한 장기간의 Colchicine 치료와 그에 따른 세포유전학적 분석)

  • 박석천
    • Korean Journal of Animal Reproduction
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    • v.18 no.1
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    • pp.63-70
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    • 1994
  • Thirty ewes received typical trauma to their oviducts and uterine horns from surgical embryo collection procedures. Ten percent Dexamethasone was used as an irrigant on the exposed abdominal tissue prior to closing the incision. The treatment group received 17mg colchicine Om! lewe) and the control group was administered a 1.0ml placebo(PSS). Fifteen ewes that were initially treated with 17mg /im colchicine showed acute colchicine toxicity within 2-5 days after initial treatment and were removed from the study. Due to acute colchicine toxicity at 17mg, the colchicine level was lowered to 8, 4 and 2mg(4 ewes/group). Treatments consisted of daily injections of colchicine. One ewe in the 8mg group developed toxicity on day 5. Therefore, ewes were then administered colchicine every other day from day 6 to day 14 postsurgeryat 4 and 2 mg. the second laparotomy was performed 9 weeks after first treatment. Following second laparotomy, the treatment group(n=5) received 4 mg colchicine every day for 14 days and there was no clinical symptoms of colchicine toxicity. The third laparotomy was performed by the same operators 5 weeks after final treatment and the adhesions scored. Adhesion grading was based on a scale of 0-4, with 4 being the most severe. The results of adhesion grading(> 3) at second laparotomy were not significantly different(P>0.05)between the two groups. Adhesion formation observed at third laparotomy showed a reduced, but not significant reduction (P>0.05) in the colchicine-treated ewes when compared with the controls. Ten ewes(5 control and 5 treatment)were examined cytogenetically by bone marrow analysis five days post-treatment. There was no difference(P>0.05)in the incidence of numerical or structural aberrations between the two groups.

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Vehicle Running Characteristic Simulator using Induction Motor (유도전동기를 이용한 차량주행특성 시뮬레이터)

  • Byun, Yeun-Sub;Kim, Young-Chol;Mok, Jei-Kyun
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.60 no.10
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    • pp.1903-1914
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    • 2011
  • In this paper, we propose vehicle running characteristic simulator. The developed simulator is configured by two induction motors which are directly coupled with each other. One motor is to simulate the vehicle drive and another motor is to simulate the vehicle dynamic load including running resistance, gradient resistance and adhesive characteristics between rail and wheel. The running characteristics of vehicle are modeled by numerical formulas. These are programed by software of embedded controller. Thus, it is possible to change several running characteristics during the running test freely and instantly. To evaluate the feasibility of the simulator, the experiments on slip and adhesion coefficient are performed. Additionally the adhesion control and speed control of vehicle are tested with simulator. Experimental results show that the simulator can produce the driving characteristics similar to the vehicle system.

Study on Maximum Adhesive Effort Estimation using Disturbance Observer (외란관측기를 이용한 최대 점착력 추정에 관한 연구)

  • Jun, K.Y.;Lee, S.H.;Oh, B.H.;Kang, S.U.;Lee, H.G.;Kim, Y.J.;Han, K.H.
    • Proceedings of the KIEE Conference
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    • 2001.07b
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    • pp.1120-1122
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    • 2001
  • In electric motor coaches, the rolling stocks move by the adhesive effort between rail and driving wheel. Generally, the adhesive effort is defined by the function of both the weight of electric motor coach and the adhesive effort between rails and driving wheel. The characteristics of adhesive effort is strongly affected by the conditions between rails and driving wheel. When the adhesive effort decreases suddenly, the electric motor coach has slip phenomena. This paper proposes a re-adhesion control algorithm which uses the maximum adhesive effort by instantaneous estimation of adhesion force using disturbance observer. Based on this estimated adhesive effort, the re-adhesion control is performed to obtain the maximum transfer of the tractive effort.

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Interfacial and Pull-out Properties of PVA and PET Fiber with UV Irradiation in Cementitious Composites (시멘트 복합체 내에서 UV처리에 따른 PVA 및 PET섬유의 계면 및 매입인발특성)

  • Jeon, Esther;Lee, Sang-Soo;Yun, Hyun-Do
    • Proceedings of the Korea Concrete Institute Conference
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    • 2006.05b
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    • pp.401-404
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    • 2006
  • Much of requirements to the civil and building structures have been changed in accordance with the social and economic progress. Ductility of high performance fiber reinforced cementitious composites(HPFRCCs), which exhibit strain hardening and multiple crackling characteristics under the uniaxial tensile stress is drastically improved. In HPFRCC application, PVA fiber has been dominantly used as a reinforcement because of its excellent alkali resistant nature as well as high strength. But the inherent strong hydrophilicity of PVA fiber promotes the moisture absorption in cement matrix and thus it may cause the corrosion of steel structure. Therefore, it is necessary to control the interfacial adhesion of cement composites. In present study, to control the interfacial adhesion of the cementitious composites reinforced by PVA fiber, UV irradiation of the PVA fiber were performed and their effects on the adhesion property and general characteristics were investigated extensively.

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Improvement of Re-adhesion Control Performance Using Estimation of Maximum Adhesive Force (최대점착력 추정을 이용한 철도차량의 재정착제어 성능 개선)

  • Kim, Woo-Seok;Kim, Yong-Seok;Sul, Seung-Ki
    • Proceedings of the KIEE Conference
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    • 1998.11a
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    • pp.163-167
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    • 1998
  • In this paper an improved re-adhesion control scheme is proposed for IC4M(1-Controller 4-Motors) traction system. It is well known that the coefficient of adhesion between wheel and rail has a maximum value at a certain slip velocity. In the proposed scheme, maximum adhesive force is estimated by an observer and the driving torque of motor is controlled to set maximum adhesive force. The simulation results are presented.

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Prevention of Adhesion Formation by Use of Carboxymethylcellulose and Ibuprofen in Rats (쥐에서 Carboxymethylcellulose 및 Ibuprofen을 이용한 유착형성 방지에 관한 연구)

  • Choi Min-Cheol;Lee Hyo-Jong;Kim Gon-Sup
    • Journal of Veterinary Clinics
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    • v.10 no.2
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    • pp.203-214
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    • 1993
  • With the use of a rat surgical model, the ability of carboxymethylcellulose and ibuprofen in the reduction of abdominal adhesion was examined. Seventy seven female rats were randomly divided into 7 groups : (1) control, (2) 2% CMC, (3) 3% CMC, (4) ibuprofen 25mg, (5) ibuprofen 50mg, (6) combination of ibuprofen 25mg and 2% CMC and(7) combination of ibuprofen 50mg and 3%, CMC. Following induction of abrasion injuries on ileum, colon and both uterine horns with a surgical blads, the rats in groups (2), (6) were infused with 2% CMC solution singly or in combined Infection of 25 mg/kg of ibuprofen for three consecutive days, the rats In groups (3), (7) were infused with 3% CMC solution singly or In combined Injection of 50mg/kg of ibuprofen for three consecutive days. The rats in groups (4), (5) were injected only with 25 mg or 50 mg/kg of ibuprofen for three consecutive days. After 10 days the abdominal cavities were opened and the appearance of formed adhesion were graded. The changes of body weight, CBC and blood chemicals were also evaluated at 3, 6 and 10 days after operation. In ileum, the rats in the groups (2), (6) and (7) showed less adhesion formation. In colon, there were significant differences(p<0.05) in adhesion formation in all treated groups as compared to control. In both uterine horns, there were significant decrease(p<0.05) of adhesion formation in groups(2), (6) and (7) in comparison with other groups. The increasing rate of body weight was evident in group (3) and fibrinogen concentrations at 6 and 10 days revealed significant decrease (p<0.01) in group (7), whereas there was no consistent change in CBC and blood chemicals. Therefore, it can be sugested that the infusion of 2% CMC solution with or without the injection of 25 mg/kg of ibuprofen and 3% CMC solution with the injection of 50 mg/kg of ibuprofen are effective and safe following abdominal surgery,

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Effect of Chitosan-Trimer on the Prevention of Postoperative Intraperitoneal Adhesion Formation in Rats (랫트에서 Chitosan-Trimer가 복강유착에 미치는 영향)

  • Kwon, Eun-ju;Jang, Kwang-ho;Jang, In-ho
    • Journal of Veterinary Clinics
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    • v.18 no.3
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    • pp.257-264
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    • 2001
  • This study was performed to investigate the effects of chitosan-trimer (CT) on the prevention of postoperative adhesion formation in the rate model. All animals divided into PBS (control), 1% CT, 3% CT, and chitin treated group. The mean adhesion score in 1% CT group (1.03$\pm$0.63), 3% CT group (0.64$\pm$0.53) and chitin group (1.67$\pm$0.71) was found to be lower than that in control group (2.07$\pm$0.81). More favorable adhesion prevention was achieved in 3% CT group (0.64$\pm$0.53) in comparison with the control group, 1% CT group, and chitin group without any hemorrhagic complications. A statistically significant difference was observed in adhesion formation between control group and 3% CT group (p<0.001). In control group, 44 of 45 sites (97.7%) formed adhesions between the intestine defects. In contrast, 3% CT was effective in reducing the incidence of adhesion formation to 17 to 45 sites (62.2%) (p<0.05). The locations of adhesions were observed in serosa-serosa (60%), serosa-mesentery (13.3%), serosa-connective tissue of testis (10%), omentum-liver (10%), serosa-omentum (3.3%), serosa-cecum (3.3%), and serosa-incision (0%). On the results of histological analysis, grade of inflammation and fibrosis at the sites of postoperative peritoneal adhesion formation were not significantly different in all groups. But, 3% CT showed the lowest score of inflammation and fibrosis. In 3% CT group, the rate of increase of plasma fibrinogen was significantly lower compared with that in control group from pre-operation to 10 days later (p<0.05). There were no appreciable difference in the CBC, leukocyte differential counts and total protein concentrations among four groups. In conclusion, our data suggested that CT should be effective on reducing adhesion formation in experimental rat models. The results also showed that 3% CT does not adversely affect normal wound healing and healthy recovery after operation.

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Effect of Administration of Sodium Carboxymethylcellulose and Dextran on Prevention of Adhesion Formation on Uterus and Embryo Collection in Rabbits (Sodium Carboxymethylcellulose 및 Dextran의 투여가 토끼 자궁의 유착방지와 수정란에 미치는 영향)

  • 이효종;강태영;윤희준;최민철
    • Journal of Veterinary Clinics
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    • v.13 no.2
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    • pp.144-148
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    • 1996
  • The effectiveness of sodium carboxymethylcellulose (SCMC) and deztran in the prevention of adhesion formation on the uterus and embryo collection in rabbits was elucidated. Following induction of adhesion on uterus and uterine horns by abrasion and retrograde flushing of embryos in gonadotropins primed rabbits, the solutions of saline (for control), 1% SCMC, 10% dextran and a synthetic solution of 1% SCNC and 10% dextran in saline were infused in the abdominal cavity at the dose of 5 ml/kg of body weight. The average percentage of adhesion was 11.1, 28.6, 41.7 and 73.3% in the rabbits infused with the synthetic, 1% SCMC, 10% dextran and saline solutions, respectively. The synthetic solution was more effective than other solutions in the rabbits. The average number and recovery rate of embryos were significantly (P<0.01) higher in the synthetic solution group than 1% SCMC, 10% dextran or saline solution groups. Among the collected embryos in the groups, the distribution of the normal embryos was higher in the synthetic solution group (99%) and the 10% dextran solution group (95.7%) than the 1% SCMC solution group (78.4%) and saline (66.2%). Theretore, a synthetic solution which is combined with 1% SCMC and 10% deztran in saline can be effectively used for the prevention of adhesion formation after uterine surgery and embryo collection.

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Hot AC Anodising as a Cr(VI)-free Pre-treatment for Structural Bonding of Aluminium

  • Lapique, Fabrice;Bjorgum, Astrid;Johnsen, Bernt;Walmsley, John
    • Journal of Adhesion and Interface
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    • v.4 no.2
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    • pp.21-29
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    • 2003
  • Hot AC anodising has been evaluated us pre-treatment for aluminium prior to structural adhesive bonding. Phosphoric and sulphuric acid hot AC anodising showed very promising adhesion promoter capabilities with durability comparable with the best standard DC anodising procedures. AC anodising does not required etching prior to anodising and offers u pre-treatment time down to 20 seconds. The interface/interphase between the aluminium substrate and the adhesive was investigated in order to get a better understanding of the involved adhesion mechanisms and to explain the long-tenn properties. The alkaline medium formed at the oxide layer/adhesive interface has been shown to induce a partial dissolution of the oxide layer leading to the formation of metallic ions which diffuse in the adhesive (EPMA measurements). The effect of diffusion of the Al ions on adhesion and joint durability is still uncertain but studies showed that pre-bond moisture affected the joints durability and to some extent the diffusion length. specially for DC anodised samples. So far no direct correlation could be established between the diffusion length d and the joints durability but new trials with better control over the elapsed time between bonding and adhesive curing are expected to help getting a better understanding of the involved mechanisms.

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Surface energy assisted gecko-inspired dry adhesives

  • Rahmawan, Yudi;Kim, Tae-Il;Kim, Seong-Jin;Lee, Kwang-Ryeol;Moon, Myoung-Woon;Suh, Kahp-Yang
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.449-449
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    • 2011
  • We reported the direct effect of intrinsic surface energy of dry adhesive material to the Van der Waals and capillary forces contributions of the total adhesion force in an artificial gecko-inspired adhesion system. To mimic the gecko foot we fabricated tilted nanohairy structures using both lithography and ion beam treatment. The nanohairy structures were replicated from Si wafer mold using UV curable polymeric materials. The control of nanohairs slanting angles was based on the uniform linear argon ion irradiation to the nanohairy polymeric surface. The surface energy was studied utilizing subsequent conventional oxygen ion treatment on the nanohairy structures which resulted in gradient surface energy. Our shear adhesion test results were found in good agreement with the accepted Van der Waals and capillary forces theory in the gecko adhesion system. Surface energy would give a direct impact to the effective Hamaker constant in Van der Waals force and the filling angle (${\varphi}$) of water meniscus in capillary force contributions of gecko inspired adhesion system. With the increasing surface energy, the effective Hamaker constant also increased but the filling angle decreased, resulting in a competition between the two forces. Using a simple mathematical model, we compared our experimental results to show the quantitative contributions of Van der Waals and capillary forces in a single adhesion system on both hydrophobic and hydrophilic surfaces. We found that the Van der Waals force contributes about 82.75% and 89.97% to the total adhesion force on hydrophilic and hydrophobic test surfaces, respectively, while the remaining contribution was occupied by capillary force. We also showed that it is possible to design ultrahigh dry adhesive with adhesion strength of more than 10 times higher than apparent gecko adhesion force by controlling the surface energy and the slanting angle induced-contact line of dry adhesive the materials.

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