• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.358-365
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• 2020

This study was conducted to evaluate the apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of amino acids in feed ingredients for use as protein sources in swine feed. A total of six weaned pigs (Landrace×Yorkshire×Duroc, 14.4±0.35kg) surgically fitted with a T-cannula in the distal ileum were used in this study and were randomly allotted to a 6×6 Latin square design. Corn germ, corn gluten meal (CM), corn gluten feed (CF), chlorella (CH), and lysine co-product (LC) were used for evaluation, and the experimental periods of each ingredient included 5 days for adaptation and 2 days for collection. CH and LC had significantly higher (p<0.05) AID of lysine (79.1% and 78.7%, respectively). The AID of methionine was not significantly different among all feed ingredients. The AID of threonine of CH was significantly higher (p<0.05) than those of other ingredients and was 81.8%. CH, LC, and CM had higher (p<0.05) SID of lysine (80.4%, 79.5%, and 77.0%, respectively). The SID of methionine showed no difference among all treatments. CH showed 81.8% SID of threonine, which was significantly higher (p<0.05) than LC and CF. In conclusion, chlorella and lysine co-product showed the greatest AID and SID of amino acids, which makes them potentially valuable feed ingredients for use as protein sources in swine feed.

• Journal of Life Science
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• v.27 no.8
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• pp.896-901
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• 2017

This study was performed to investigate the protective effects of succinic acid of Succiniter against carbon tetrachloride ($CCl_4$)-induced hepatotoxicity in rats. After an adaptation period of one week, Sprague-Dawley rats were administered succinic acid of Succiniter at 200 mg/kg every day for 21 days. Then $CCl_4$ (3.3 ml/kg) was intraperitoneally injected into rats of the other groups except the normal group, five hours after the last treatment of succinic acid of Succiniter on day 21. The succinic acid-treated group showed 93.20% and 88.76% of inhibitory effects in aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities, respectively, compared with the $CCl_4-treated$ group. The succinic acid-treated group showed inhibition of malonedialdehyde (MDA) by 85.17% compared with the $CCl_4-treated$ group. The succinic acid-treated group in liver homogenate promoted effects of 38.65% and 47.99% in superoxide dismutase (SOD) and catalase (CAT), respectively, compared with the $CCl_4-treated$ group. In conclusion, the AST and ALT activities of the succinic acid-treated group were both decreased compared with the $CCl_4-treated$ group. The MDA level of the succinic acid-treated group was decreased compared with the $CCl_4-treated$ group. However, the SOD and CAT levels of the succinic acid-treated group in liver homogenate were both increased compared with the $CCl_4-treated$ group. Also, histological examinations showed that the liver cell necrosis and centrilobular congestion aggregation induced by $CCl_4$ were clearly eliminated by treatment with succinic acid of Succiniter. These results suggest that succinic acid of Succiniter has a protective effect against liver damage and could be used in the development of the appropriate drug.

• Journal of Korean Medicine Rehabilitation
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• v.30 no.2
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• pp.139-152
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• 2020

Objectives To explore the traffic injury patients' experience on health care utilization of Korean Medicine (KM) practice and perception of health care system for developing a Korean medicine clinical practice guideline (CPG) of traffic injuries by survey method. Methods Two hundred ten patients in suffering from traffic injuries were surveyed from September 1st, 2019 to January 31th, 2020 at 2 University Hospitals (Pusan National Korean Medicine Hospital and Kyung Hee Korean Medicine Hospital at Gangdong) and 1 Spine Specialty Hospital (Jaseng Hospital of Korean Medicine). A structured questionnaire of experience on health care utilization of KM practice and perception of health care system of was distributed to responders by visits and all data were statistically analysed. Results Survey results showed high satisfaction of patients with the experience of KM treatments in order of daoyin exercise (7.8±2.3), chuna manual therapy (7.7±4.0), pharmacoacupuncture (7.4±3.0) etc. Safety concerns were reported in 9.1% subjects and 205 (97.6%) patients answered that collaboration with KM and western medicine is necessary for patients with traffic injuries. For the patients' requirement for extending insurance coverage, the most required therapy was chuna manual therapy (57.5%) and pharmacoacupuncture (42.0%). Conclusions This study presented the realistic patient-centered perception of KM practice and health care system in Korea. These results will provide basic data to be reflected in the process of adaptation for the revision of Korean Medicine CPG for traffic injuries.

• Journal of Life Science
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• v.27 no.9
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• pp.1078-1085
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• 2017

Free radicals have long been considered damaging to various tissues. An excessive amount of reactive oxygen species (ROS) is known to have detrimental effects on the body and to be linked to numerous pathological conditions, such as cardiovascular disease, cancer, diabetes, and skeletal muscle atrophy. On the other hand, recent findings suggest that ROS is important for maintenance and development of cellular activity. Cells respond to increased oxidative stress by adaptive changes in the expression of a variety of proteins involved in the maintenance of cellular integrity. ROS is also essential for skeletal muscle function and metabolism. It is well known that physical exercise has many health benefits. Paradoxically, physical exercise also stimulates the production of ROS, which result in oxidative stress. Based on evidence amassed in the past decade, exercise itself may be considered an antioxidant because training increases the expression of antioxidant enzymes. In this review, we discuss the processes underlying the generation of ROS and its role in exercise-induced adaptation based on recent evidence. Furthermore, we discuss the possible role of NADPH oxidase in exercise-induced activation of insulin signaling and its effect on longevity.

• Korean Journal of Agricultural and Forest Meteorology
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• v.18 no.4
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• pp.298-306
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• 2016

Planting date shift is one of the means of adapting to climate change in Kimchi Cabbage growers in major production areas in Korea. This study suggests a method to estimate the potential yield of Kimchi Cabbage based on daily temperature accumulation during the growth period from planting to maturity which is determined by a plant phenology model tuned to Kimchi Cabbage. The phenology model converts any changes in the thermal condition caused by the planting date shift into the heat unit accumulation during the growth period, which can be calculated from daily temperatures. The physiological maturity is estimated by applying this model to a variable development rate function depending either on growth or heading stage. The cabbage yield prediction model (Ahn et al., 2014) calculates the potential yield of summer cabbage by accumulating daily heat units for the growth period. We combined these two models and applied to the 1km resolution climate scenario (2000-2100) based on RCP8.5 for South Korea. Potential yields in the current normal year (2001-2010) and the future normal year (2011-2040, 2041-2070, and 2071-2100) were estimated for each grid cell with the planting dates of July 1, August 1, September 1, and October 1. Based on the results, we divided the whole South Korea into 810 watersheds, and devised a three - dimensional evaluation chart of the time - space - yield that enables the user to easily find the optimal planting date for a given watershed. This method is expected to be useful not only for exploring future new cultivation sites but also for developing cropping systems capable of adaptation to climate change without changing varieties in existing production areas.

• The Korea Journal of Herbology
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• v.33 no.6
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• pp.35-42
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• 2018

Objectives : The aim of this study was to investigate whether the extract of Coptidis Rhizoma inhibits inflammation in chronic cold stress (CCS)-exposed mice or not. Methods : Coptidis Rhizoma extract (CRE) was made by reflux with distilled water. Male ICR mice (7 weeks old) were divided randomly into 5 groups: (1) control, (2) CCS, (3) CCS+CRE 100 mg/kg, (4) CCS+CRE 300 mg/kg, (5) CCS+CRE 1,000 mg/kg groups. Mice were orally administered once a day for 14 days starting from 1 day before CCS. Group (2)-(5) were exposed to CCS conditions that maintained at $4^{\circ}C$ for 2 h once a day for 14 days. The levels of serum cortisol and hypothalamic prostaglandin E1 (PGE1) and PGE2 were measured by enzyme-linked immunosorbent assay kit. The expression levels of several pro-inflammatory factors like heat shock protein 70 (HSP70), c-fos, and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) were measured by western blot analysis in mouse hypothalamus. Results : Oral administration of CRE 1,000 mg/kg significantly suppressed the increase of serum cortisol levels in mice exposed to CCS. CCS-exposed mice had significantly increased the expression of HSP70, c-fos, and NF-kB in hypothalamus, while CRE treatment significantly attenuated the elevation of these pro-inflammatory factors. The ratio of PGE2/PGE1 was also higher in CCS-exposed mice than control group. CRE treatment significantly reduced the increase of PGE2/PGE1 ratio induced by CCS. Conclusion : These findings suggest that Coptidis Rhizoma may work as a potential agent to modulate inflammatory responses under the condition of cold adaptation formed by CCS.

• The Journal of Korean society of community based occupational therapy
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• v.2 no.1
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• pp.13-23
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• 2012

Objective : The purpose of this study was to provide evidence for effectiveness of community-based rehabilitation methods and results after traumatic brain injury through systematic review. Methods : The materials of the research were collected by retrieving research items in the areas of "community-based rehabilitation" and "traumatic brain injury" from the data base of Ovid and PubMed. Among the collected materials, 7 research results are suggested concerning the effectiveness of rehabilitation in community-based after traumatic brain injury in terms of subjects, measurement tools, cure methods and results. Results : Characteristics of subjects were diverse in numbers of subject, age, level of impairment and duration of disease. Research designs were all experimental studies and the most outcome parameters of community-based rehabilitation was occupational performance(27.7%). Cure methods were used occupational therapy programs concerning rehabilitation programs, cognitive therapy, cognitive behavioral therapy and home based occupational therapy. Conclusion : The results implied that community-based rehabilitation is effective on occupational performance, participation, prevention, and occupational justice, partially effective on adaptation, health and wellness, and non effective on the role competence. It is suggested the future research need to be done to develop intervention programs and studies in every types.

• The Journal of the Korea Contents Association
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• v.15 no.8
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• pp.345-355
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• 2015

This article attempted to find out the moderating effects of social support in the relationship between perceived stigma, depression of student with disabilities(SWD) and their adjustment of campus life. For the purpose of the reason the data were collected from 108 SWD from questionaries in Busan city and Kyungnam province. The results were as follows. It was revealed that the factors, grade and gender, had significant difference in the level of adjusting campus life of SWD. Perceived stigma and depression of SWD had positive impact on the adjustment of campus life. Social support of SWD also had positive impact on the adjustment of campus life. This study demonstrated that social support of SWD had moderating effect in the relationship between perceived stigma, depression of SWD and their adjustment of campus life. This study verified that for the purpose of improving the adjusting level in college life of SWD, it was as important to make social support to be delivered at SWD as decreasing the perceived stigma and depression of SWD. Finally, the authors suggested some direction to solve the problem related this study question and remarked the limitation of this study.

• Journal of Digital Convergence
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• v.12 no.11
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• pp.13-21
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• 2014

In this paper, we study on an 'e-Atlas of Society & Culture(e-ASC)', to develop and implement educational courseware for marriage immigrant women, to adapt Korean society. The 'e-ASC' can help cultural adaptation, such as the understanding of Korean people's common values and behaviors and can likewise provide opportunities to contribute to Korean society, for marriage immigrant women living in Korea. E-cultural map is a useful tool for providing educational experiences and sharing a sociocultural homogeneity, using three dimensional space, for both immigrants and residents. The 'e-Atlas of Society & Culture', suggested in this paper, using the notion of an E-cultural map, has a strong point. That is to say, the immigrants have contextual limitations about Korea and Korean culture, caused by some particular events in their motherland. This atlas provides an opportunity to overcome this contextual limitations and to help understand and adapt to Korean society for these immigrants. This 'e-Atlas of Society & Culture' can be an efficient educational tool for immigrants and can help marriage immigrant women understand and adapt Korean social and cultural phenomena. They might have contextual limitations about these phenomena in their motherland.

• Journal of Korea Entertainment Industry Association
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• v.14 no.3
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• pp.63-73
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• 2020

The purpose of this study was to investigate the relationship of academic resilience, academic burnout and major satisfaction and to identify the influencing factors on major satisfaction of nursing students. Data were collected using questionnaires from 215 students who were in 3rd and 4th year of the nursing college in G city, from May to June 2019. The collected data was analyzed using descriptive statistics, pearson's correlation coefficient and stepwise multiple regression with IBM SPSS 25.0 program. The study results showed that university students in nursing scored 3.71±.56 points for academic resilience, 2.96±.52 for academic burnout, 3.78±.54 for major satisfaction. The higher the academic Resilience, the lower the academic burnout and the higher the level of major satisfaction. The factors affection the relationship of academic resilience, academic burnout and major satisfaction are interpersonal relationships and admission motive which resulted in the major satisfaction level of 44.3%. In conclusion, to enhance major satisfaction for nursing students, efficient education program development is required considering the factors that explain the major satisfaction of nursing students. Also It should be considered that required the students' talent and aptitude. So it makes sure that this will require an advanced method of studying to students' capabilities.