• 한국산학기술학회논문지
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• 제21권8호
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• pp.485-494
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• 2020

동아리 활동은 대학생들의 인간관계와 대학생활 적응에 중요한 역할을 한다. 이에 본 연구는 간호대학생의 동아리 활동이 의사소통능력과 셀프리더십에 미치는 영향을 확인하고자 시행하였다. 본 연구는 2019년 10월 15일부터 11월 30일까지 편의 표집한 일부 도시 간호학과 재학생 147명을 대상으로 하였으며, 그 중 동아리 활동 참여자는 119명이었다. 자료 분석은 IBM SPSS/WIN 21.0을 이용하여 기술통계, 𝑥²검정, t-test, hierarchical multiple regression analysis를 시행하였다. 연구 결과는 다음과 같다. 연구대상자의 의사소통능력과 셀프리더십은 중간 이상이었으며, 동아리 활동 여부에 따라서는 학년(𝑥²=8.07, p=.045), 전공만족도(𝑥²=8.26, p=.010), 의사소통능력(t=8.19, p=.005), 셀프리더십 중 행동중심적 전략(t=4.48, p=.036)에서 유의한 차이가 있었다. 대상자의 의사소통능력은 행동중심적 전략, 건설적 사고전략 및 동아리 활동수준 중 적극성이 유의한 영향요인이었다. 셀프리더십은 의사소통능력이 유의한 영향요인이었다. 따라서 대상자들의 다양한 동아리 경험은 의사소통능력을 향상시키고 그것은 셀프리더십 함양에 도움을 줄 것이다. 향후 간호대학생의 적극적인 동아리 활동을 장려하고 전문간호사의 핵심역량인 의사소통능력과 셀프리더십이 향상되는 교육적 전략을 모색해야 할 것이다.

• 한국잠사곤충학회지
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• 제48권1호
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• pp.25-27
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• 2006

누에장려품종 중 혈당강하제 개발에 적합한 품종 결정을 위하여 DNJ 함량을 정량한 결과, 봄에 사육한 금옥잠이 5.45 mg/gDW으로 DNJ 함량이 가장 높았다. 또한 누에 유전자원 원종 66품종의 DNJ 함량을 결정한 결과, 품종간 DNJ 함량 차이가 매우 큰 것으로 밝혀져, 혈당 강하제용 누에 육종시 기초자료가 될 수 있으며, 또한 DNJ 함량이 낮은 품종은 DNJ 축적 기작 연구에 많은 도움이 될 것으로 사료된다.

• 동서간호학연구지
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• 제11권1호
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• pp.33-41
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• 2005

This study was conducted to identify the effect of meridian acupressure on defecation of patients with post spinal operation. The nonequivalent control group posttest only design was used. The data were obtained from 77 post spinal operative patients, 34 in the experimental 43 in control group in Y Hospital, Seoul, Korea. The neurosurgical unit A and B ward, assigned by matched sample by the name of operation such as laminectomy and posterior lumbar interbody fusion are performed. Meridian acupressure meant the method that an examiner presses response points distributed in the pass of energy vessel. In this study, meridian acupressure program was performed on as points in order of Hegue (LI-4), Zhigou (TE-6), Zusanli (S-36), Shangjuxu (S-37), Xiajuxu (S-39), Tianshu (S-25), Taichong (L-3) which was known to be related to large intestine. Data were collected from 1, July 2003 to 1, September 2003. Meridian acupressure program was carried out for 20 minutes 4 hours after operation twice daily. In order to evaluate the effect of meridian acupressure intervention, they were asked time of bowel recovery, gas passing, and defecation though questionnaire method. Data were analyzed by the SPSS/ WIN 11.0 program. The results of this study were summarized as follows; 1. Homogeneity tests of general characteristics and operation related characteristics of the experimental group and the control group were performed. General characteristics included age, sex, defecation habit, eating pattern, fluid intake, life style, activity, usage of laxative and etc. 2. Hypotheses were verification as follows; 1) Recovery of bowel sound of the experimental group who received meridian acupressure intervention was faster than that of the control group after spinal operation (t=-6.770,P=.000). 2) Time of gas passing of the experimental group who received meridian acupressure program was faster than that of the control group after spinal operation (t=-8.003, P=.000). 3) Time to defecation of the experimental group who received meridian acupressure program was faster than that of the control group after spinal operation (t=-9.026, P=.000). 4) Abdominal discomfort due to defecation of the experimental group who received meridian acupressure program was lesser than that of the control group after spinal operation (t=-3.431, P=.001). From these results, meridian acupressure intervention was effective for recovery of bowel sound, reduce time to gas passing, time to defecation and lessen abdominal discomfort due to defecation on post spinal operative patients. And therefore this intervention can probably considered on clinical practice.

• 대한치과교정학회지
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• 제14권2호
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• pp.187-202
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• 1984

There are evidences that exogenous electric currents are capable of enhancing bone formation and resolution, and that the conversion of the bioelectric response to biochemical activity provides the directional component of orthodontic tooth movement. In addition, evidence has implicated cyclic nucleotides in alveolar bone cellular activation mechanism during orthodontic tooth movement. In view of these evidences, this study was performed to investigate the effects of exogenous electric currents on cyclic nuclotide levels in feline alveolar bone and the possible clinical application of electric currents as an additional orthodontic tool. In the first study, three groups of three adult cats were subjected to application of a constant direct current of $10{\pm}2$ microamperes to gingival tissue near maxillary canine noninvasively for 1, 3, and 7 days respectively. In the second study, three groups of three adult cats each were treated by an electric-orthodontic procedure for 1, 3, and 7 days respectively. The left maxillary (control) canine received an orthodontic force of 80gm alone at time of initiation, while the right maxillary (experimental) canine received combined force-electric stimulation (80gm of force and $10{\pm}2$ microamperes of a constant D.C. currents). Alveola, bone samples were obtain from the mesial (tension and/or cathode) and the distal (compression and/or anode) sites surrounding maxillary canines as well as from contralateral control sites. The samples were extracted, boiled, homogenized, and the supernatants were assayed for cyclic nucleotides (cAMP, cGMP) by a radioimmunoassay method. And also the amount of tooth movement was measured in the second study. On the basis of this study, the following conclusions can be drawn: 1. The fluctuation pattern of cyclic nucleotide levels in alveolar bone treated by exogenous electric currents was similar to that treated by orthodontic force. 2. The cAMP levels in alveolar bone of electrically treated teeth significantly elevated above the control values. And of electrically treated teeth, the values of the anode sites were higher than those of the cathode sites. 9. The cGMP levels in alveolar bone of electrically treated teeth elevated above the control values at the initiation phase of treatment, but dropped below the control values at time of termination. And of electrically treated teeth, the values of the cathode sites were higher than those of the anode sites. 4. The rate of tooth movement in teeth . treated by force-electric combination increased with the length of treatment as compared to that treated by mechanical force alone.

• 한국과학교육학회지
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• 제37권6호
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• pp.1005-1014
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• 2017

본 연구는 대중의 과학적 소양을 함양하기 위한 기관으로서의 과학관의 역할에 주목하고, 우리나라 과학관이 대중에게 어느 정도 영향을 미치고 있는지 알아보기 위하여 소셜 빅데이터 분석을 통해 대중의 과학관에 대한 인식과 사용 행태를 알아보고자 하였다. 이를 위해 네이버 블로그와 트위터에에서 '과학관'이 포함된 게시글들을 추출한 뒤 텍스트 네트워크 분석, 빈도 분석, 공기어 분석 및 의미 분석을 실시하고 영어권의 분석 결과와 비교해 보았다. 그 결과 블로그에서는 주로 어린 자녀를 둔 부모 층에서 과학관이 이슈가 되고 있었고, 트위터에서는 단체 관람을 하는 학생 층이 다수 드러났다. 따라서 우리나라 대중들은 과학관을 주로 아이의 체험을 위한 공간으로 활용하고 있었고, 이 경우 과학관의 프로그램과 전시에 대해서는 긍정적으로 인식하고 있었다. 한편 단체 관람하는 학생들은 다소 부정적 감정을 표출하고 있는 것으로 나타났다. 과학관과 대중과의 소통, 대중의 과학에 대한 참여 등 제 3세대적 과학관의 기능적 측면에서 외국의 사례와 비교해본 결과 우리나라 대중들은 과학관 관람 이후 관람한 과학적 내용에 대한 언급이 거의 없었고, 논쟁이나 심포지움 등 과학적 의사소통과 관련된 언급 역시 거의 없었다. 또한 해설사나 직원들도 외국과는 달리 전혀 회자되지 않고 있었다. 한편, 영어권 게시글의 동사 분석에서 '배우다', '참여하다', '듣다', '읽다', '묻다', '생각하다', '그리다' 등의 유의미한 활동과 관련된 동사들이 다수 나타난 것에 비해 우리나라 게시글에서는 '물어보다', '생각하다' 가 소수 나타나는 것에 그치고 있었다. 따라서 과학관은 과학관 관람객들이 관람을 마친 뒤에 그들의 기억에 남고 대중들 사이에서 회자될 만큼 영향력 있고 다양한 내용과 활동이 일어날 수 있도록 개선할 필요가 있겠다.

• 한국과학교육학회지
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• 제35권6호
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• pp.1063-1074
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• 2015

이 연구에서는 비유 생성 전략을 개발하여 이를 중학교 1학년 과학영재 수업에 적용하였다. 그리고 이 수업에서 5개 소집단의 과학영재들이 생성한 비유의 유형 및 과학영재들의 언어적 상호작용 양상과 비유 생성 패턴 및 비유 생성 전략에 대한 과학영재들의 인식을 조사하였다. 분석 결과, 비유 생성 전략을 활용한 수업에서 과학영재들이 개별적으로 생성한 비유는 일반적인 비유 생성 활동에서 보다 질이 좋은 유형의 비율이 높았으며, 소집단 활동을 거친 후에는 대부분 가장 좋은 유형의 비유를 생성하였다. 과학영재들의 언어적 상호작용은 각 단계의 영역별 하위 범주의 상호작용의 빈도 및 비율에서 약간 다른 경향이 나타났다. 그리고 소집단별 비유 생성 패턴은 심층적 소재 선택형, 포괄적 소재 선택형, 표면적 소재 선택형의 세 가지 유형이 나타났으며, 각 유형별로 대응 정교화 패턴이 다르게 나타났다. 과학영재들은 비유 생성 전략의 가치 및 태도 측면에서 긍정적으로 인식하고 있었으며, 비유 생성 전략이 더 정교한 비유를 생성하고, 창의적 사고를 하는데 도움이 되었다고 응답하였다. 따라서 비유 생성 전략은 과학영재들의 창의성 신장에 긍정적인 영향을 줄 것으로 기대된다.

• 한국양식학회지
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• 제9권4호
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• pp.445-452
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• 1996

어류 및 폐류내에 내재하는 내재성 ${\beta}-galactosidase$의 활성도를 분석함으로서 외래유전자의 이식시 기초자료로 활용하고자 어류 6종 및 패류 4종을 대상으로 본 실험을 행하였다. 어류에 있어서의 X-gal 염색 결과 혈청 및 근육을 제외한 모든 조직에서 모두 positive ( + ) 염색 양상을 보였다. 패류에 있어서도 어류와 같은 양상을 보여 근육을 제외한 모든 조직에서 모두 positive 염색 양상을 보였으며 더욱이 참굴에 있어서는 폐각근 및 근육에 있어 매우 진한 염색 반응을 보였다. 근육으로 부터 DNA를 추출한 후 PCR을 수행한 결과 모든 종에서 positive (+) 결과를 나타내었으며, 어패류간 그리고 각 개체간 차이는 없었다. 각 장기별 ${\beta}-galactosidase$의 활성도 측정결과 모든 종에 있어서 혈청의 활성도는 무시할 만한 수준이었고, 근육에서 가장 낮게 나타났다. 미꾸라지와 잉어에서는 신장에서 가장 높은 활성을 보였고, 틸라피아는 소화관에서 가장 높은 값을 보였다. 해산어인 넙치의 경우 돌가지미, 문치가자미의 경우에 비해 간에서 활성이 높았다. 그러나 돌가자미 및 문치가자미인 경우 신장에서 가장 높은 값을 보였다. 패류에 있어서는 소화맹낭에서 가장 높은 활성값을 나타내었고 폐각근 및 외투막에서 매우 낮은 활성값을 나타내었다. 그러나, 참굴에 있어서는 참전복, 피조개 및 진주조개 보다는 상대적으로 폐각근 및 외투근에서 높은 활성을 나타내었다.

• Journal of Periodontal and Implant Science
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• 제25권3호
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• pp.603-613
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• 1995

The purpose of this investigation was to evaluate on the biodegradability, biocompatibility and tissue regenerative capacity of synthetic bioabsorbable membranes in beagle dogs. For animal study, 9 adult beagle dogs were used to examination, on the surgical implantation of membranes and histological analysis. In each animal, the 3rd and 4th premolars of the both sides of the mandible were selected as test teeth. Two types of bioresorbable membranes including "Guidor membrane", "S-membranes" were used to examining for biological activity, and also Gore-tex membranes was used for positive control. Surgically created defects were made in 2 premolars of both sides of the mandible at $3{\times}4mm^2$ in size and tested membranes were implanted in the defected area. A plaque control regimen was instituted with daily tooth brushing with a 0.1% chlorhexidine digluconate during experimental periods. All the experimental animals were sacrificed after 2, 4, and 8 weeks from surgery and undecalcified slides were prepared using the "sawing and grinding" technique described by Donath and Breuner". In biodegradability, all the membranes were started their biodegradation from two weeks after implantation and gradually demolished of their frame morphology from eight weeks. However, demolition of membranes in 8 weeks after implantation was highest in Guidor membranes and followed by S-membranes. Biocompatibilityof two kinds of biodegradable membranes including Guidor and S-mambrane were shown to be well tolerated to the surrounding tissue, and were minimal accumulation of inflammatory cell infiltration around the implanted membranes to compare with Gore-tex membrane. Regeneration of defected alveolar bone was initiated from two weeks of membrane implantation and new bone formation was gradually increased from that time. However, pattern of new bone formation on the defected areas of two kinds of biodegrable membranes was almost similar and quite competitive comparing with Gore-tex membrane. These results implicate that bioresorbable membranes should be highly useful tool for guided tissue regeneration of periodontal defects.

• 대한의생명과학회지
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• 제24권1호
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• pp.43-49
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• 2018

Electrocardiogram (ECG) is a widely used method to diagnose electrical activity of heart. Although it is a reliable and easy method, ECG could be interfered by electrical signals. One of the interfering signals is electromyogram (EMG) that is caused by muscle contraction in any parts of the body except heart. To avoid the EMG noise, an examinee is advised to be relaxed on supine position while measuring ECG. Sometimes, patients who can't put their arms and legs down on bed due to some reasons such as cast on arms or legs necessarily have the EMG noise. But detailed information about how much of the noise could be induced by positional change of arms and legs has not been reported. Here we examined the noise by analyzing ECG data from 14 candidates, 7 males and 7 females. The ECG data was obtained using the standard 12 lead ECG. EMG noise was induced by raising arms and legs at $90^{\circ}$, $60^{\circ}$ or $30^{\circ}$. Because arms are located close to the heart, noise by the raised arms was analyzed toward left or right arm separately. All of the examinees showed similar pattern of the EMG noise. EMG noise by positional change of left or right arm was clearly monitored in different limb leads. Change of leg positions induced the noise that was monitored in aVF of augmented leads and II and III of limb leads. There was a difference in degree of the noise between male and female examinees. In addition to the EMG noise, decrease of PR interval was monitored in particular positional changes, which was prominent in male examinees. These results will enlarge fundamental understanding about EMG noise in ECG.

• 생물정신의학
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• 제16권1호
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• pp.5-14
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• 2009

Objectives : Most of the mechanisms reported for antidepressant drugs are the enhancement of neurite outgrowth and neuronal survival in the rat hippocampus. Neural cell adhesion molecule 140(NCAM140) has been implicated as having a role in cell-cell adhesion, neurite outgrowth, and synaptic plasticity. In this report, we have performed to elucidate a correlation among chronic antidepressant treatments, NCAM140 expression, and activation of phosphorylated cyclicAMP responsive element binding protein(pCREB) which is a downstream molecule of NCAM140-mediated intracellular signaling pathway in the rat hippocampus. Methods : Fluoxetine(10mg/kg) was injected acutely(daily injection for 5days) or chronically(daily injection for 14days) in adult rats. RNA and protein were extracted from the rat hippocampus, respectively. Real-time RT-PCR was performed to analyze the expression pattern of NCAM140 gene and western blot analyses for the activation of the phosphorylation ratio of CREB. Results : Chronic fluoxetine treatments increased NCAM140 expression 1.3 times higher than control in rat hippocampus. pCREB immunoreactivity in the rat hippocampus with chronic fluoxetine treatment was increased 4.0 times higher than that of control. Conclusion : Chronic fluoxetine treatment increased NCAM140 expression and pCREB activity in the rat hippocampus. Our data suggest that NCAM140 and pCREB may play a role in the clinical efficacy of antidepressants promoting the neurite outgrowth and neuronal survival.