• 제목/요약/키워드: Activity Schedule

검색결과 194건 처리시간 0.028초

2D 숲동영상 및 Virtual Reality 숲동영상 시청이 성인의 스트레스 감소에 미치는 영향 (Effect of 2D Forest Video Viewing and Virtual Reality Forest Video Viewing on Stress Reduction in Adults)

  • 홍성준;정다워;이정도;김다영;김수진;박범진
    • 한국산림과학회지
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    • 제108권3호
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    • pp.440-453
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    • 2019
  • 본 연구는 평면 숲동영상 및 VR 숲동영상 시청이 성인의 스트레스 감소에 미치는 영향을 밝히기 위해 수행되었다. 실험은 인공기후실에서 진행되었으며, 피험자는 40명이 참가하였다. 피험자의 스트레스를 유발한 후 2D 회색동영상, 2D 숲동영상, VR 숲동영상을 5분 동안 시청하게 하였다. 실험하는 동안 연속적으로 심박변동성을 측정하여 자율신경계 활동을 평가하였으며, 각 실험 후 설문지를 이용하여 심리 상태를 평가하였다. 생리적 측정 결과 2D 숲동영상은 2D 회색동영상보다 스트레스 지수 감소효과가 크고, HF 증가효과가 크며, 심장박동수 감소효과가 크다는 사실을 확인하였다. 또한 VR 숲동영상은 2D 회색동영상 시청보다 스트레스 지수 감소효과가 크고, LF/HF 증가효과가 크며, 심장박동수 감소효과가 크다는 사실을 확인하였다. 심리적 측정 결과 피험자들은 2D 회색동영상보다 2D 숲동영상과 VR 숲동영상을 더 쾌적하고, 자연적이며, 진정된다고 느꼈다는 사실을 확인하였다. 그리고 2D 숲동영상과 VR 숲동영상이 2D 회색동영상보다 긍정적인 정서를 증가시키고 부정적인 정서를 감소시킨다는 사실을 확인하였다. 이상의 결과를 바탕으로 2D 숲동영상과 VR 숲동영상의 시청은 스트레스 상황을 벗어나 2D 회색동영상을 시청하는 것보다 더 스트레스 지수를 감소시키고, 심장박동수를 감소시키는 것으로 판단된다. 또한 2D 숲동영상은 부교감 신경계의 활동을 증가시키고 VR 숲동영상은 교감 신경계의 활동을 증가시키는 차이점이 있는 것으로 판단된다. 마지막으로 VR 숲동영상의 교감 신경계의 활동 증가는 스트레스, 긴장 등의 부정적 교감신경 활성이 아닌 신기함, 호기심 등의 긍정적 교감신경 활성으로 판단된다. 이러한 연구의 결과가 산림치유의 시각적 효과에 대한 기반이 되길 기대하고, 임업분야에서 4차 산업혁명의 기술인 VR의 활용이 넓어지는 기반이 되길 기대한다.

건설공사에서의 현금흐름 예측 (CASH FLOW FORECASTING IN CONSTRUCTION PROJECT)

  • 박형근
    • 한국건설관리학회:학술대회논문집
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    • 한국건설관리학회 2002년도 학술대회지
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    • pp.35-41
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    • 2002
  • 현금흐름 예측에 대한 많은 자료들은 실제 Tendering Stage(입찰단계) 혹은 Planning Stage(계획단계)의 Model들로서 Feasibility Study를 위한 Cash Flow Forecasting 주였다. 이 Model 들의 기법들은 하나의 Project를 통해서 Cash Flow를 예측하는 Model들이 대부분이고, 예측 방법은 주로 통계적인 접근 방법, 예들 들어 과거 Data를 통해서 Cash Flow 예측 곡선 Model 만들고 Project 유형별 상수나 변수 값을 부여함으로서 예측에 적용하였거나, Fuzzy Technique을 이용하여 Progress와 Cash Flow의 관계를 수식화 한 Model에 관리자의 경험과 판단에 의한 Forecasting Model도 제시되었다. 또한 Cash Flow가 아닌 기성 Flow 및 Cost Flow를 기준으로 한 표준화된 Model이 제시되었다 다른 한편으로는 Schedule과 Cost를 통합한 방법들, 즉, 간단한 주요 Activity와 Cost를 연결한 방법, Activity와 Cost Item과의 연결, 또는 Work Package를 이용한 방법, 마지막으로 좀더 정확도를 기하기 위한 Resource Level까지의 통합을 통해서 Project의 Cash Flow를 예측한 연구들이 이루어 졌다. 그러나 이러한 모든 예측 방법은 실제로 Planning Stage에 Forecasting한 Model로서 현재 진행중인 Project에 적용하기에는 그 정확도면에서 상당히 떨어지고, 대부분의 Model들은 Cash Flow 예측에 가장 중요한 Time lags를 고려하지 않았다. 또한Resource까지 연결은 현장 Engineer들의 많은 작업과 관리를 요구하게 된다. 본 연구는 시공단계에서의 Project의 현금흐름 예측에 관한 연구로서 매출계획과 건설회사의 실행 예산을 이용하여 현금흐름예측을 할 수 있는 Model을 제시하였다. 특히 건설공사의 현금흐름 예측의 중요한 요소인 Cash-Out에 대하여, 공사비 구성요소인 자재, 노무, 중기, 외주, 경비등 각 Resource의 보할(Weights)을 실 공사원가에 따른 보할의 변화와 Resource들의 Time Lag를 적용 기존 연구자의 Model과 다른 Model을 제시하였다. 또한 기존 연구자들의 Model과 비교하여 편리성, 정확도 및 신뢰성이 높은 Model임도 증명하였다.

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음악요법이 치매노인의 인지기능, 행동, 정서에 미치는 효과 (The Effect of Music Therapy on Cognitive Function, Behavior and Emotion of Dementia Elderly)

  • 심향미;정승희
    • 성인간호학회지
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    • 제13권4호
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    • pp.591-600
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    • 2001
  • Purpose: This study was to observe the effects of music therapy on the cognitive function, behavior, and emotions of elderly dementia patients, and to seek musical mediation for them. This study was conducted with patients in the Dementia Sanitarium in C City from March 13 to April 17. Method: The design of research was a nonequivalent control group non-synchronized design and the subjects were 25 patients-15 of whom were in the experimental group with 10 in the control group. The music therapy consisted of favorite music listening in the morning, favorite music group singing activity after lunch, and relaxing music listening after dinner. The schedule was followed 6 days a week for 2 weeks for a total of thirty-six session. The effect of music therapy was measured by MMSE-K and the behavior and emotion measuring equipment which had been derived by the researcher. The verification of the effects is that the score of cognitive function, behavior, and emotions of the experimental and the control group which were measured after the therapy had been applied was analyzed by descriptive statistics and t - test using SPSS WIN program. Result: 1) The degree of cognitive function of the experimental group which was received the music therapy is $11.53{\pm}5.37$ which is a little higher than the control group which is $11.20{\pm}6.32$, but it is not significant statistically (t= .14, p= .887). The first hypothesis which had assumed the recepients would have had a higher cognitive function level than the other was rejected. 2) Behavior score of the experimental group that received the music therapy is $68.90{\pm}7.86$ which is higher than the control group which is $66.40{\pm}11.13$, but it is not significant statistically(t= .61, p= .548). The second hypothesis which had assumed the recepients would have had a higher behavior level than the other was rejected. 3) Emotions score of the experimental group that received the music therapy is $42.13{\pm}5.04$ which is higher than the control group which is $35.20{\pm}6.12$, and it is significant statistically(t=3..09, p= .009). The third hypothesis which assumed the recepients would have had a higher emotion level was supported. Conclusion: music therapy which is composed of listening to music and group singing activity is an effective strategy for improvement of the emotions of the dementia elderly. But, the effect of music therapy on the cognitive function and behavior of elderly dementia patients is not significant statistically.

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토마토 엽위별 광합성 특성 분석 (Characterization of Photosynthetic Rates by Tomato Leaf Position)

  • 김성은;이문영;김영식
    • 원예과학기술지
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    • 제31권2호
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    • pp.146-152
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    • 2013
  • 토마토 잎들의 엽위별 광합성 특성을 조사하고, 잎의 연령과 개화속도를 엽위별 광합성 특성과 비교분석하였다. 일중 광합성 속도 특성실험에서는 일출 전 2시간부터 일몰 후 3시간까지 1시간마다 4번째 화방의 하부엽 3매의 광합성 속도를 측정하였다. 3개체를 반복으로 총 2회 조사하였다. 토마토의 일중 광합성 속도는 일출 후 1시간 동안 급격히 증가한 후, 일몰 2시간 전까지 일정하게 유지되는 양상을 보여 급액의 시작과 마감시각을 결정하는데 적용할 수 있을 것으로 사료된다. 엽위별 광합성 속도 특성실험에서는 1화방부터 4화방까지 각 화방의 하부에 있는 본엽 3개씩을 대상으로 광합성 속도를 조사하였다. 또한 광합성 특성을 분석하는데 적용하기 위해 개화속도를 조사하였다. 광합성속도는 엽위에 관계없이 꽃이 만개하는 시기를 정점으로 지속적으로 감소하는 경향을 보였다. 이는 만개 이후에는 해당 화방 이하의 잎의 활력이 감소하고 생육단계가 노화단계로 이동하기 때문으로 사료된다. 따라서 토마토의 개화속도와 광합성 속도는 서로 밀접한 관련이 있는 것으로 나타났다. 연구결과, 생육단계(엽령)의 차이에 의해 각 화방별 광합성 속도는 차이가 있으나, 광합성 속도로 작물의 활력을 판단하려 할 때는 개화하고 있는 화방의 하부엽을 조사하는 것이 매우 효과적일 것으로 판단된다.

농촌 일차 보건사업에 있어서 마을건강원 업무량 및 업적에 관한 연구 (A Study on Performance and Achievement of Village Health Workers in Rural Primary Health Care Program)

  • 허달영;이명숙;염용태;김순덕
    • 농촌의학ㆍ지역보건
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    • 제12권1호
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    • pp.36-53
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    • 1987
  • It is utmostly important to establish the efficient fitable way of peoples' active participation in primary health care especially in the areas where the public or governmental service input for the basic health care is insufficient like as in rural areas of Korea. In light of above reason, this study focused mainly on the evaluation of roles and activities of village health workers (VHWs) who were selected from grass- root level of village people in order to derive further motivation for active participation. This is believed to be a sort of feedback mechanisms. Actually, the authors collected the activity reports of VHWs who had been devoting themselves in the primary health care services of Jeomdong Area, of Yeoju Gun one of Korea University Community Health Action Programmes and survey record on the VHWs activity from correspondent people. 1 hose data were analyzed through computer programmed package. The activities performed by VHWs were limited to the performance in 1985 for conveniance. The summarized results were as follows; 1) General characteristics of VHWs. Among a total of 28 VHWs in the area, about 39.3g of them have been replaced up to the date since the implementation in 1983, because of moving out, occupational employment and of others. The age of majority (75.0%) lied between the range of 30-50, and educational background of 67.9% belonged to category of primary school graduation, about 50% of them experienced to be or were also entiled "chief of women club" of corresponding villages. 2) Work-load of VHWs. Each VHW was assigned for tasks of health care for average 55 households of 248 persons. They shared approximately 6 days a month for the activity in average and it covered 17 cases of basic health care in a month. A half of the VHWs performed home visits irregularly without solidified schedule. 3) Work performance analysis. Informations collected through VHWs were compared with data from official vital registration at local administration center "Myon Office" in 1985. VHWs collected 100.8 of new born, 116.2 of death, 58.3 of move in and 74.8 of move out in comparison with 100.0 of official registration each. Pregnant women of 79.8% of mothers among the total pregnancy of 94 which were confirmed as normally delivered or aborted cases by all means afterwards had been detected by VHWs as being pregnant and all of them received some of antenatal cares by VHWs. All(100%) of delivered women were detected by VHWs through home visits and they were cared postnatally. Whereas, according to the records of birth registration, the places of delivery were clinic in 33.7%, and mother's home in 66.3%, VHWs reported them to be clinic in 48.9%, midwifery in 20.2%. It was cleared that most of misinformation was caused by uncautious filling of birth registration at notification. Among the total of 717 eligible women under age 44 years, family planning status of 92.6% was reported by VHWs confirming practice of control to be 70.8% of reported fertile women. 4) Attitude of VHW on the roles and functions. Although 92.0% of VHWs expressed VHWs to be worthwhile, only 52.0% of them had dignity and satisfaction in their activity and 44.0% of them had passive attitude of working saying they followed direction regardlessly. Concerning difficulties in performance as a VHW, 60.7% of them pointed out lacking of medical and health related knowledge by themselves. Still, 64.0% of them thought visiting unfamilier house to be awful and 40.0% complained forms of activity to be difficult and hard. It was also revealed that 56.6% confessed lack of interest on community health service itself. Most of VHWs needed more educational training especially on clinical fields such as cares of gynecological diseases, hypertension, diabetes, and other chronic diseaes of the aged. Regular on-the-job basic trainings were said to be needed twice a year.

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교육과정, 수업, 평가의 일체화를 위한 가정과 과정 중심 수행과제 개발 (Development of Process-centered Performance Task For Curriculum·Instruction·Assessment Alignment based on 2015 Revised Home Economics Curriculum)

  • 이경숙;유태명;양지선
    • 한국가정과교육학회지
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    • 제30권4호
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    • pp.165-185
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    • 2018
  • 본 연구는 2015 개정 교육과정에서 강조하고 있는 교육과정, 수업, 평가의 일체화를 실현하기 위한 가정과 과정 중심 수행과제 개발 및 적용사례를 제시하는데 목적을 두었다. 이러한 목적에 따라 개발 절차는 수행의 명료화, 수행과제 및 채점기준 개발, 수행평가 실시 및 결과의 3단계로 수행하였으며 연구 결과는 다음과 같다. 첫째, 수행의 명료화 단계에서는 2015 개정 기술·가정 교육과정의 분석을 통해 성취기준-학습목표-평가목표가 일관성을 가지도록 평가시기, 횟수, 반영비율, 수행평가의 영역별 배점, 평가유형을 포함한 학기별 평가계획을 수립하였다. 둘째, 수행과제 및 채점기준 개발 단계에서는 교육과정 내용체계를 분석하여, 수행과제를 결정하고 과제 소요시간, 참여 방법, 산출물의 형태를 고려하여 개별과제와 모둠과제를 포함한 포트폴리오, 프로젝트 활동 및 지식시장, e-NIE 유형의 수행과제를 개발하였다. 개발된 수행과제는 교과 전문적 학습공동체 협의를 통해 타당성을 검토하고 재수정하여 세부적인 수행과제 채점기준을 개발하였다. 셋째, 수행평가 실시 및 결과 단계에서는 교사의 수업방향에 따라 교과 운영을 계획을 수립하고 교수·학습과 연계하여 블록 수업으로 시간표를 편성한 후 수행평가를 실시하였다. 이후 교과 전문적 학습공동체에서 개발된 수행평가 과제와 수행평가 산출물, 수업적용에 대한 수업성찰을 토대로 수행평가 과제를 재수정 하였다. 본 연구를 통해 학습자의 성장을 도울 수 있는 학습의 과정을 중시하는 수행과제를 개발함으로써 교사의 수업전문성과 현장의 수업개선에 기여할 수 있다.

간호대학생의 욕구구조에 관한 일 연구 (A STUDY IF PERSONALITY STRUCTURE AND HIERARCHY OF NEEDS IN COLLEGIATE NURSING STUDENTS)

  • 최계영
    • 대한간호학회지
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    • 제4권1호
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    • pp.38-49
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    • 1974
  • Presently, the performance level of the college student has received a great deal of attention, particularly in the area of professional education. The problem of under achievement, especially in areas dealing with science and technology, has gone through considerable investigation by numerous Psychologists and Educators. Thus for, however, they have not been successful in determining conclusively the non-intellectual factors involved. The maladjustment problem of these students has been a thorn in the side of nursing education for some time. This topic has been discussed among nursing educators without any tangible results. Furthermore, the fact that the number of students who withdraw from nursing education programs before graduation has increased. This represents a major problem for nursing education. This problem area had increased attention drawn to it on October 1957, when Russia successfully launched to first satellite "Sputnik" into space. Various studies seem to indicate that factors related to over achievement and under.achievement can be found in the motivation of the students. This study is aimed at testing 3 hypotheses which hopefully will lead to a better understanding of the learning activities of nursing students and to determine some of their nonintellectually personality traits. Hypothesis I: learning activities in nursing students and persona1ity are correlated, there will be significant differences in personality need structures between 4 classes of nursing collegiate students. Sub-hypothesis: There will also be significant differences in the degree of student satisfaction in her major subject. Hypothesis I: If there is a special personality need structure which is required for the clinical learning activity in general, then there will be significant differences between the personality need structures of under-achievers and overachiever. Hypothesis II : If each clinical nursing subject requires different personality need structures, then there will be differences in personality need structure between the different clinical groups Methodology: 1. Tool: A Korean translation and correction of the Edwards Personal Preference Schedule of U.S.A. was used. 2. Subject and Test Method: Subjects were nursing students at Yonsei University, who enrolled for Fall semester of 1971. The Researcher herself executed the test for the test for the class as a group, and the absent students were tested indidually. Out of 307 students, 293 students (95.4%) were reported. 3. Statistical treatment: The mean and standard deviation for each of the 15 personality need variables were computed and the value of T-test was obtained to determine the differences in the personality need structures between each group. Results: 1, For the first hypothesis, the personality need structures between each of the 4 classes and the reported degree of satisfaction in major subject showed significant differences. Therefore the hypothesis I was accepted. 2. The comparison of personality need structure of under-achievers and over-achievers in clinical fields showed significant differences. Thus hypothesis II was accepted. 3. Personality need structure between clinical subject groups showed significant differences therefore the 3rd hypothesis was accepted.

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기준모델을 사용한 종합사업관리용역비 산정방법(ICEP) 연구 (A study on the method for the Integrated Cost Estimate based on Project(ICEP) of program management with typical model)

  • 백명창;박준모;박길범;김옥규
    • 한국건설관리학회논문집
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    • 제16권1호
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    • pp.119-128
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    • 2015
  • 국내 종합사업관리 용역비 산정을 위하여 대부분의 경우, 유사 사업관리 산정사례를 참고하여 추정하거나 과업참여자의 경험을 바탕으로 비용을 산정하였음을 알 수 있다. 이는 사업관리비 산정에 대한 정확성이 떨어져 사업을 주관하는 발주기관에서는 사업계획 및 예산 반영이 어려우며, 추정치에 의한 용역비 산정으로 향후 설계변경 등의 사업관리용역비 증가의 원인이 되기도 한다. 따라서 발주자와 용역 참여자가 보다 정확한 용역비를 산정하여 변경사항 등으로 인한 비용증가와 분쟁을 최소화하기 위해서는 용역비 산정기준을 객관적이고 과학적인 방법으로 적용할 필요가 있다. 종합건설사업 관리의 용역비 산정을 위해 기존의 경우에는 사례와 경험을 기초로 한 Top-Down 방식으로 접근하였다면, 본 연구에서는 사업관리 업무를 세부단계 및 활동(Activity)으로 분류하고 단계별로 WBS를 부여하여 각각 부여된 코드에 일정과 비용을 산정하는 Bottom-Up 방식의 사업관리 용역비를 산정하는 것으로, 용역비 산정을 위한 프로젝트 기준모델을 개발하고 프로젝트별 보정계수를 적용하여 용역비용을 산정하는 방식으로 이를 ICEP이라고 명명하였다. 또한 산정된 해당 과업의 비용과 추후 실적자료를 분석하여 보완함으로써 프로젝트별 특성을 반영한 종합사업관리 용역비 산정으로 효율적인 건설사업 관리가 가능해진다.

산후조리원의 표준화 관리 지침을 위한 연구 - 산모와 신생아 관리현황을 중심으로 - (A Study for the Development of Standardized Management Manuel in Sanhujoriwon - Centered on the Management of Women & Newborn -)

  • 정은실;유은광
    • 여성건강간호학회지
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    • 제8권2호
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    • pp.301-313
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    • 2002
  • The purpose of this study was to develop the frame for standardized manual for Sanhujoriwon by finding out the status of the management of women & newborn in Sanhujoriwon, like postpartum care center. The subjects were 95 staffs of 22 Sanhujoriwon agreed on oral consent, in Seoul and Bundang, Korea. Data were collected from Sep. 15 to Oct. 24, 2001. The instrument used for this study was a structured questionnaire consisted of 16 items of general characteristics & educational characteristics about postpartum care, 31 items of degree of management of women's postpartum care (Cronbach's $\alpha$.93 ), 24 items of degree of management of newborn's care(Cronbach's $\alpha$.94 ), 10 items of methods of management of women's postpartum care, 8 items of methods management of newborn's care. The data were analyzed by the SPSS/PC+ program using frequency, percentage, mean, standard deviation, t-test, ANOVA and Pearson correlation coefficient. The results of the study were as follows ; 1. The mean of the degree of management for postpartum women was 4.1. The mean score for the degree of management of general postpartum care for women was 4.00 & traditional postpartum care(Sanhujori) was 4.20. The degree of management of traditional postpartum care was higher than general postpartum care for women. 2. The degree of management for newborn : The mean score for the degree of management of newborn was 4.37. 3.There was a strong positive correlation between general postpartum care and traditional postpartum care($r=.744^{**}$), and postpartum mother care and newborn care($r=.798^{**}$). 4.The basic frame for the management of the women and newborn in Sanhujoriwon. 1) For women: Integrated postpartal care Physical management : Vital sign & BP check, contraction of uterus, form and amount of lochia, management of personal hygiene, management of breast & breast-feeding, management of postpartum exercise, prevention of infection, symptom & sign of high risk and prevention & management of high risk condition; Emotional-psychological management: assessment and management of mother-baby attachment, emotional state; Educational management : education of vaccination schedule, urinary incontinence, rearing infant, breast-feeding ; and Environmental management : temperature, humidity, disinfection, cleaning, light, infection control integrated with 6 principles of Sanhujori. 2) For newborn Physical management : check of vital sign, management of umbilical cord, jaundice, prevention of infection, management of diaper rash; Emotional-psychological management : assessment of sleep, crying, activity, response of mother-baby attachment; and Environmental management : temperature, humidity, disinfection, cleaning, light, infection control integrated with 6 principles of Sanhujori. In conclusion Sanhujoriwon must be health care center for the postpartum women and newborn. Therefore, the establishment of various laws and regulations in such a way to meet the realistic needs of Sanhujoriwon as a health care center for women and infants future health should be done. The standardized management manual based on the results is absolutely required above all.

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Efficacy and Tolerability of Weekly Docetaxel, Cisplatin, and 5-Fluorouracil for Locally Advanced or Metastatic Gastric Cancer Patients with ECOG Performance Scores of 1 and 2

  • Turkeli, Mehmet;Aldemir, Mehmet Naci;Cayir, Kerim;Simsek, Melih;Bilici, Mehmet;Tekin, Salim Basol;Yildirim, Nilgun;Bilen, Nurhan;Makas, Ibrahim
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권3호
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    • pp.985-989
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    • 2015
  • Background: Docetaxel, cisplatin, 5-fluorouracil (DCF) given every three weeks is an effective, but palliative regimen and significantly toxic especially in patients who have a low performance score. Here, we aimed to evaluate the efficacy and tolerability of a weekly formulation of DCF in locally advanced and metastatic gastric cancer patients. Materials and Methods: 64 gastric cancer patients (13 locally advanced and 51 metastatic) whose ECOG (Eastern Cooperative Oncology Group) performance status (PS) was 1-2 and who were treated with at least two cycles of weekly DCF protocol as first-line treatment were included retrospectively. The weekly DCF protocol included $25mg/m^2$ docetaxel, $25mg/m^2$ cisplatin, and 24 hours infusion of $750mg/m^2$ 5-fluorouracil, repeated every week. Disease and patient characteristics, prognostic factors, treatment response, grade 3-4 toxicity related to treatment, progression free survival (PFS) and overall survival (OS) were evaluated. Results: Of the patients, 41 were male and 23 were female; the median age was 63 (29-82) years. Forty-one patients were ECOG-1 and 23 were ECOG-2. Of the total, 81.2% received at least three cycles of chemotherapy. Partial response was observed in 28.1% and stabilization in 29.7%. Overall, the disease was controlled in 57.8% whereas progression was noted in 42.2%. The median time to progression was 4 months (95%CI, 2.8-5.2 months) and median overall survival was 12 months (95%CI, 9.2-14.8 months). The evaluation of patients for grade 3-4 toxicity revealed that 10.9% had anemia, 7.8% had thrombocytopenia and 10.9% had neutropenia. Non-hematologic toxicity included renal toxicity (7.8%) and thrombosis (1.6%). Conclusions: In patients with locally advanced or metastatic gastric cancer who were not candidates for DCF administered every-3-weeks, a weekly formulation of DCF demonstrated modest activity with minimal hematologic toxicity, suggesting that weekly DCF is a reasonable treatment option for such patients.