• Applied Biological Chemistry
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• v.50 no.3
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• pp.147-153
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• 2007

To search for a molecular design of a new breast cancerous inhibitory active compound, 2D-QSAR and HQSAR between the substituents of flavopiridol analogues as substrates and their breast cancerous inhibitory activities against MCF-7 cell were analyzed and discussed quantitatively. It was found that the dispersion with molecule and steric hindrance with substituents will have a tremendous impact on the inhibitory activities from the 2D-QSAR model (1). Also, MR constant is better than that of MS constant as animportant factor. The inhibitory activities from 2D-QSAR model (2) were dependent upon the optimum MR constant (MR = 126 $Cm^3/mol$). Optimized HQSAR model (V) exhibited the best predictability of the inhibitory activities based on the cross-validated $r^2_{cv}$($q^2$= 0.583) and non-cross-validated conventional coefficient ($r^2_{ncv}$= 0.982). From the contribution maps, the inhibitory activity by the imino group on $C_9$ atom was higher than that of the hydroxyl group of $C_8$ atom on the A ring in molecule. Therefore, we can confirm that the dispersion by substituents in molecule is the most important factor in inhibitory activities against MCF-7 cell.

• Journal of Korean Academy of Nursing
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• v.25 no.1
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• pp.45-60
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• 1995

This study investigated the effects of education program conducted through individual home visit by CHPs, which was developed ,by the operational re-search technique for families of dementia patients. (Yeo Shin Hong et at,1994) The study was conducted in the form of a primary experimental design with 43 people as subjects, including dementia patients and family member in several Myon areas of Chungcheong Namdo between June 10 and August 20, 1994. The data was collected by questionnaires through the home visit by the CHPs. The results of study are as follows. 1. There is no difference in the quality of life between before and after the education program. 2. Role stress 'before the education program' was significantly different than 'after the education program'. 3. There was no difference in the feeling of burden between before and after the education program. 4. There was a significant difference in the abnormal behaviors of patients between before and after the education program. 5. The knowledge of dementia by the patient's family increased significantly after the education program, compared to that of 'before the education program'. 6. There was a significant difference in the attitude of family members toward the education program on dementia between before and after the education program. 7. The results of analysis on the coefficient relationship of various variables showed that the age of patients and family members have a significant correlation with role stress(p=.01). 8. In the subjective evaluation of family members on changes in actual nursing actions and the improvement of knowledge and technique in terms of daily living, (including abnormal behavior of patients, adjustment of environment for patients, activity programs for patients, communication technique with patients, ensuring the safety of patients, clothing, meals and elimination, 60-65% of family members responded that their knowledge had increased. As for improvement in techniques for each item, the technique for communication with patients showed the greatest improvement while the action program method for patients showed the least change. As for the nursing service provided to patients, most respondents showed a positive change. The specific items for which more than 80% respondents answered positively were as follows : recognizing the demand of patients, getting patients to do simple house works, talking softly and gently, removing dangerous things, preparing comfortable clothes that are easy to put on and take off, and limiting water consumption at night. As a result of study, the following suggestions can be made. The purpose of the study was to examine the effect of an education program developed and applied for dementia patients and family members in the community. This needs to be compared with a similar study conducted in the urban setting. In addition, a community service program (ex : nursing hem and shelter) including the application of the education program should be developed and the study done to investigate its effect.

• Journal of Korean Public Health Nursing
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• v.15 no.2
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• pp.262-274
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• 2001

This study was undertaken to grasp the relationship between perceived health status, health conception and health promoting behavior in the elderly. The subjects for this study were 157 old persons in Kyung-ju city. Data were collected by interview with questionnaires from August 24 to October 10, 1999. Analysis of the data was done by SPSS program using descriptive statistics, t-test, ANOVA, Pearson Correlation Coefficient, stepwise multiple regression. The results were summarized as follows 1. For the practice of health promoting behavior. the mean score was 2.52. The factor of the highest mean score was nutrition(3.02) and factor of the lowest mean score was exerciset(2.03). 2. According to age(F=3.35, P=.012), sex(t=2.26, P=.025), marital status (F=5.08, P=.007), education(F=4.22, P=.003), family numbed(F=5.31, P= .006), people living together (F=2.77, P=.044), economic status(F=7.10, P=.00l), average monthly pocket money (F=3.35, P=.012), there were differences of health promoting behavior. 3. According to age(F=3.40, P=.01l), sex(t=4.30, P=.000), education(F=8.55, P=.000), economic status(F=12.59, P=.000), average monthly pocket money(F=4.26, P=.003), present disease(t=-8.41, P=.000), there were differences of perceived health status. According to marital status(F=3.36, P=.037), education(F=2.89, P=.038), there were differences of health conception. 4. Performance in the health promoting behavior was significantly correlated with perceived health status(r=.272, P=.00l), health conception(r=.345, P=.000) 5. The combination of well-being health conception and average monthly pocket money explained $24.7\%$ of the variance of health-promoting behavior. On the basis of the above findings the following recommendations are made; Nursing interventions enhancing exercise or activity, accountability for health, stress management of the elderly must be provided. And Cost-effective health promoting program for the elderly must be developed.

• Journal of Korean Society for Atmospheric Environment
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• v.26 no.5
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• pp.517-532
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• 2010

After establishment of Banwol industrial complex in 1987, Ansan city becomes the largest industrial sector development in Gyeonggi-do, Korea. As the population and industrial activity grow over this region, toxic air pollutants, particularly POPs (Persistent Organic Pollutants) from various emission sources have been major public concerns. Air samples for POPs monitoring were collected at the industrial sites ($A_2$), residential sites ($B_1$, $B_2$), commercial site (C), and rural/remote site (D) of the area of Ansan during 2008 with a prolonged industrial sampling site $A_1$ from 2001 to 2008. All samples were analysed for 2,3,7,8 substituted-polychlorinated dibenzo-p-dioxin and dibenzofurans (PCDD/Fs) and dioxin like polychlorinatd diphenyls (dl-PCBs). In site $A_1$, a steady decline of their concentrations from 2003 to 2008 was observed due to the reinforced emission guideline from waste incinerators. The average concentration of the PCDD/Fs and dl-PCBs ranged between 0.118 pg-TEQ/$m^3$ (rural/remote site D) and 0.532 pg-TEQ/$m^3$ (industrial area $A_2$). These level were generally consistent with previous studies in Gyeonggi-do, while higher than other places. Most of PCDD/Fs congener were partitioned into particle phase, whereas dl-PCBs were partitioned into gas phase. The logarithm of gas-particle partition coefficient $K_P$ of dl-PCBs and PCDD/Fs were well correlated with sub-cooled liquid vapor pressure $P_L$. The slope $m_T$ of log $K_P$ versus log $P_L$ for PCDD/Fs (-1.22) and dl-PCBs (-1.02) in industrial area ($A_2$) were high compared to other residential/commercial area. It suggests that this area was likely influenced by the direct emission source of PCDD/Fs and dl-PCBs. To simulate the partition of PCDD/Fs and dl-PCBs between gas and particle phase, Junge-Pankow model ($P_L$-base) and $K_{oa}$ model were applied. It was found that J-P model was more suitable than the $K_{oa}$ model in this study.

• Women's Health Nursing
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• v.2 no.1
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• pp.138-157
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• 1996

Recently, there has been increase perception of health promotion with development of the economic state and science. Individual's responsibility and psychosocial factors have impacted on the individual's lifestyle. Health promotion can be maintained or improved through changes of lifestyle of individuals. Also, there has been supported results of health behavior health has been focused on menopausal symptom and reproductive organ. Until recently, little research has been available on the health or health care of midlife women. The purpose of this study was to explain relationship between health promoting lifestyle and hardiness, gender role characteristics. A total of 254 items of data were obtained from randomly selected subjects. The data collected from the interviews were analyzed using SPSS, yielding frequency, mean. t-test, ANOVA, Pearson Correlation, Stepwise multiple regression. The result of this study are as follows : 1) For the health promoting lifestyle, the mean score was 116.3, the highest score was nutrition(3.30) and interpersonal support(2.86), the lowest score was exercise(1.68). The highest subscale for the hardiness was committment(2.44). Also for the gender role characteristics was higher than median score(37.8). 2) There was a statistically difference the demographic variables. A total health promotion lifestyle was predicted by income and marriage satisfaction, hardiness was predicted by education, income, marriage satisfaction, support person and gender role characteristics was predicted by education. 3) With regard to the relationship among health promoting lifestyle, hardiness, gender role characteristics, the correlation coefficient between health promoting lifestyle and hardiness was r=-.48, p<.001. Also there were significant correlation between health promoting lifestyle and gender role characteristics(r=.22, p<.01), hardiness and gender role characteristics(r=-.39, p<.001). 4) A stepwise multiple regression analysis was done on the total health promoting lifestyle score using the demographic variables, hardiness subscale and gender role characteristics for independent variables. A total of 25% of the variance was explained inthe total health promoting lifestyle by the control, challenge and marriage satisfaction. In conclusion, hardiness and gender role characteristics were engaged in health promoting activity in midlife women. This study also provides new information about the health practices that midlife women report they practice. Therefore, nursing intervention to increase women's health have to be planed program that consider on the basis the results of this study.

• Journal of the Korean Wood Science and Technology
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• v.15 no.4
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• pp.32-44
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• 1987

This study was carried out to analyze and furecast the domestic demand for plywood in Korea by regression models with time-series data for 16 years(1970-85). The results obtained were summarized as follows. 1. To analyze domestic demand for plywood, GNP, PWI and CWI were used as independant variables. The domestic demand equation was computed as follows: $^{in}DDP$=0.65186+1.29412 $^{in}GNP$-0.28385 $^{in}PWI$-1.05011 $^{in}CWI$ Where DDP : Domestic demand for plywood(1000 S/F) GNP: Gross national product (Billion won) PWI : Real wholesale price index of plywood CWI: Real wholesale price index of construction materials. 2. Among independant variables reflecting on the production activity of plywood industry, GNP was the most decisive in forecasting the domestic demand for plywood. 3. The significance can be recognized highly because the decision coefficient of the forecasting model which is obtained by using time series data is 0.9. 4. According to the estimated regression coefficients for GNP, PWI and CWI, GNP shows positive relation while PWI and CWI show negative relation. 5. An annual average increase rate of demand for plywood was 9.4 percent during expect period. Therefore, it was decreased slightly than that of 10.2 percent during sample period.

• Journal of Energy Engineering
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• v.19 no.2
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• pp.73-80
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• 2010

A solid oxide fuel cells(SOFC) is a clean energy technology which directly converts chemical energy to electric energy. When the SOFC is used in cogeneration then the efficiency can reach higher than 80%. Also, it has flexibility in using various fuels like natural gases and bio gases, so it has an advantage over polymer electrolyte membrane fuel cells in terms of fuel selection. A typical cathode material of the SOFC in conjunction with yttria stabilized zirconia(YSZ) electrolyte is still Sr-doped $LaMnO_3$(LSM). Recently, application of mixed electronic and ionic conducting perovskites such as Sr-doped $LaCoO_3$(LSCo), $LaFeO_3$(LSF), and $LaFe_{0.8}Co_{0.2}O_3$(LSCF) has drawn much attention because these materials exhibit lower electrode impedance than LSM. However, chemical reaction occurs at the manufacturing temperature of the cathode when these materials directly contact with YSZ. In addition, thermal expansion coefficient(TEC) mismatch with YSZ is also a significant issue. It is important, therefore, to develop cathode materials with good chemical stability and matched TEC with the SOFC electrolyte, as well as with high electrochemical activity.

• Journal of the Korean Society of Food Culture
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• v.17 no.2
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• pp.197-213
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• 2002

In order to establish the processing condition of rapid- and low salt-fermented liquefaction of anchovy (Engrulis japonica), effect of temperature on crude enzyme activity of anchovy viscera, pretreatment conditions, and the minimum content of adding NaCl were investigated. The minimum limitation of NaCl content for anchovy liquefaction was 10%. Sample A(water adding, heating, adding 10% NaCl): chopped whole anchovy adding 20% water and then heating for 9 hrs at $50^{\circ}C$ and then adding 10% NaCl and then fermented at room temperature$(8-29^{\circ}C)$ for 180 days. Sample B(water adding, heating, adding 13% NaCl): chopped whole anchovy adding 20% water and then heating for 9 hrs at $50^{\circ}C$ and then adding 13% NaCl and then fermented at room temperature for 180 days. Sample C(adding 13% NaCl): chopped whole anchovy and then adding 13% NaCl and then fermented at room temperature for 180 days. Sample D(adding 17% NaCl): whole anchovy adding 17% NaCl and then fermented at room temperature for 180 days. The content of free amino acids such as aspartic acid, serine and threonine fluctuated severely according to the pretreatment methods. Possibly they might be recommend quality indices of standardization for salt-fermented liquefaction of anchovy. As for the relation between fermentation period(X) and individual free amino acid(Y), five kinds of free amino acids such as glutamic acid, valine, glycine, lysine, and alanine showed highly significant in their coefficient of determination in most of samples. They might be recommend as quality indices for salt-fermented liquefaction of anchovy during fermentation. The difference of taste between products of the rapid- and low salt-fermented liquefaction and the traditional salt-fermented liquefaction were caused by their composition of the free amino acids ratios, in which were umami, sweet, and bitter taste in the extracts of anchovy during fermentation. The appropriate fermentation period of the sample A was shorten 30 days than the sample B and 60 days than the samples C and 90 days than the sample D in the processing of anchovy.

• Korean Journal of Food Science and Technology
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• v.18 no.2
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• pp.130-136
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• 1986

'Shingo' pears were seal-packaged in polyethylene (PE) film with different thickness of 0.04. 0.06, 0.07, and 0.08mm and stored for five months in an experimental storehouse with the temperature varyine 0 to $7^{\circ}C$ and relative humidity varying 86 to 89%. The atmosphere in PE film bags was modified to 5-l4% oxygen with 3-5% carbon dioxide depending on the film thickness and the storage period. Packaging of pears with PE film effectively reduced the weight loss, which resulted in good appearance after 5 months' storage, while non-packaged pears showed a slight wilt. Decay occurrence was not significantly different among the treatments. but role browning occurred a little more in packaged lots than in non-packaged lot. The sensory panel rated the pears front 0.07mm-thick bag highest in flavor, texture, and juiciness, which might be due to the high sugar content and low titratable acidity. The firmness of pear flesh decreased with the stogare time and its change was found to be highly correlated with that of cellulase activity (correlation coefficient= -0.946). Thisresult indicated that cellulase might be one of the enzymes responsible for the softening of pear fruit during storage.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.4 no.3
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• pp.275-284
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• 2006

In the measurement of gamma rays emitted from the nuclide in the radioactive waste drum, to analyze the nuclide concentration accurately, it is necessary to use the proper calibration standards and to correct for the attenuation of the gamma rays. Two drums having a different density were used to analyze the nuclide concentration inside the drum in this study. After carrying out the system calibration, we measured the gamma rays emitted from the standard source inside the model drum with changing the distance between the drum and the detector. The measured values were corrected with the three kinds of gamma attenuation correction methode, as a results, the error was less than 10 % in the low density drum and less than 25 % in the high density drum. The measured activity in the short distance was more accruable than in the long distance. The transmission correction for the mass attenuation showed good results(very Low error) compared to the mean density and the differential peak correction method.