Background: This study was performed to provide a long-term bacterial seal through the formation of reparative dentin bridge, calcium silicate-based pulp capping materials have been used at sites of pulpal exposure. The aim of this study was to evaluate the mineralization-inducing potentials of calcium silicate-based pulp capping materials (ProRoot MTA [PR], Biodentine [BD], and TheraCal LC [TC]) in human dental pulp cells (HDPCs). Methods: Specimens of test materials were placed in deionized water for various incubation times to measure the pH variation and the concentration of calcium released. The morphology of HDPCs cultured on the specimens was examined using a confocal laser scanning microscope (CLSM). Alizarin red S staining and alkaline phosphatase assays were used to evaluate mineralization-inducing potentials of the capping materials. Results: BD showed the highest calcium release in all test periods, followed by PR and TC. (p<0.05). All experimental groups showed high alkalinity after 1 day, except at 14 days. BD showed the highest cell viability compared with PR and TC after 1 and 3 days, while TC showed the lowest value (p<0.05). The CLSM analysis showed that cells were well adhered and expressed actin filaments for all pulp capping materials. Mineralization by PR and BD groups was higher than that by TC group based on alizarin red S staining. BD showed significantly higher alkaline phosphatase activity than PR and TC, while TC showed the lowest value (p<0.05). Conclusion: Within the limitations of the in vitro study, BD had higher mineralization-inducing potential than PR and TC.
Torre, Gerwin Louis Tapan Dela;Ponsaran, Kerstin Mariae Gonzales;de Guzman, Angelica Louise Dela Pena;Manalo, Richelle Ann Mallapre;Arollado, Erna Custodio
Parasites, Hosts and Diseases
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제55권4호
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pp.409-416
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2017
The high prevalence of pediculosis capitis, commonly known as head lice (Pediculus humanus capitis) infestation, has led to the preparation of a community-based pediculicidal ointment, which is made of common household items and the extract of Tinospora crispa stem. The present study aimed to evaluate the safety, efficacy, and physicochemical characteristics of the T. crispa pediculicidal ointment. The physicochemical properties of the ointment were characterized, and safety was determined using acute dermal irritation test (OECD 404), while the efficacy was assessed using an in vitro pediculicidal assay. Furthermore, the chemical compounds present in T. crispa were identified using liquid-liquid extraction followed by ultra-performance liquid chromatography quadruple time-of-flight mass spectrometric (UPLC-qTOF/MS) analysis. The community-based ointment formulation was light yellow in color, homogeneous, smooth, with distinct aromatic odor and pH of $6.92{\pm}0.09$. It has spreadability value of $15.04{\pm}0.98g{\cdot}cm/sec$ and has thixotropic behavior. It was also found to be non-irritant, with a primary irritation index value of 0.15. Moreover, it was comparable to the pediculicidal activity of the positive control $Kwell^{(R)}$, a commercially available 1% permethrin shampoo (P>0.05), and was significantly different to the activity of the negative control ointment, a mixture of palm oil and candle wax (P<0.05). These findings suggested that the community-based T. crispa pediculicidal ointment is safe and effective, having acceptable physicochemical characteristics. Its activity can be attributed to the presence of compounds moupinamide and physalin I.
PURPOSE: This study concerns the wheelchair-based rehabilitation of elderly people, investigating muscle activity and coordination of upper limbs during wheelchair-based new millennium health gymnastics with varying elbow exercise velocity. METHODS: Twelve elderly people participated in new millennium gymnastics twice per week during 12-weeks. The group was separated into 0.4, 1.0, and 1.6 Hz groups (controlled by the metronome speed). Range of motion was measured by electrogoniometer, electromyography signals used root mean square values. The data application was normalized using reference voluntary contraction (%RVC). Upper limb (wrist and elbow joint) data gathered while standing up after the "falling on hips" was investigated in terms of coordination of angle-angle plots. One-way ANOVA, paired t-test and Scheffe's post hoc comparisons, were used for statistical analyses. RESULTS: There were results taken before and after the experiments. The results demonstrated a significant improvement in the triceps brachii and flexor carpi radialis of the 0.4 Hz group (p<.05). There was significant difference in the triceps brachi of the 1 Hz group. No significant differences were found in all muscles of the 1.6 Hz group. Muscle co-activation indexes of the 0.4 Hz group were larger than the others. The 0.4 Hz graph was turning point synchronized clockwise. The 1 Hz graph was out of phase with the negative slope. The 1.6 Hz graph was turning point synchronized counterclockwise, and uncontrolled factor phase was offset on angle-angle plots. CONCLUSION: It is found that improvement of muscle activity and upper limbs coordination of elderly people using wheelchair-based new millennium gymnastics is optimal with elbow exercise velocity with a frequency of 0.4 Hz.
Future space is currently getting a great deal of attention to apply ubiquitous computing technology. At the same time, various ubiquitous technology-based products are being developed with service scenarios in the views of diverse user groups predicted. Since these service models and scenarios need to be tested to verify effectiveness, it requires researchers to predict spatial shapes and service scenarios for future domestic environment that fulfills diverse future spatial requirements including ecological and user-oriented spaces, extended amenity getting maximum benefits from technology, etc. To support these developments, the need to make a physical test-bed, a real building model, is essential. However building a physical test-bed generally is economically expensive and even if the test-bed could be settled, it must be carefully designed before it is built In this paper, we suggest a virtual smart test-bed, called "V-PlaceLab", using virtual reality techniques. This system allows not only to inspect a scenario with the aid of computer simulation on a virtual environment, but also to design a virtual test-bed mentioned above.
This study has assessed the anti-oxidative activities and cytotoxic effects of Lithospermum erythrorhizon ethanol extract and measured the effects of tyrosinase inhibition activities with a goal of estimating the usage of the medicinal plant as an ingredient of cosmetics. First, to perform a basic test on the extract, pH and UV-spectrum were measured. According to the measurement, the extract had control functions at pH 5.5, and maximum absorbance occurred at 530nm. In particular, DPPH (1-1-diphenyl-2-picryl-hydrazyl)-inhibiting activity (IC50) and polyphenol content were 149.81 ${\mu}g/mL$ and $51.28{\pm}2.52$ mg/mL respectively. In addition, as extract concentration increased, tyrosinase inhibition activities improved as well. In raw 264.7 cell-based MTT assay, cell survival rates were 98% at 1000 ppm and 153% at 100 ppm. Therefore, it's been confirmed that there is almost no cytotoxin. According to the test results above, it appears that the Lithospermum erythrorhizon ethanol extract would be effective in anti-oxidation and application as a cosmetic ingredient.
Objectives: The purpose of this study was to investigate health behavior, job stress of police officer in Korea. Methods: It was a descriptive study, and subjects were comprised 135 police officer by reported questionnaires. The data were analyzed by t-test, ANOVA(Sheffe's test), and Pearson's correlation using SPSS/WIN 22.0. Results: The job stress level of the subjects was 41.30 and Dietary practice guideline score was 4.52, moderate activity practice day was 2.48, waling practice day was 3.87. There was a significant difference in the job stress among the characteristics of the subjects according to their work experience and position. Health promoting behaviors and job stress were negatively correlated with dietary practice guideline score and moderate exercise practice days, and positive correlation between smoking and drinking. Conclusion: Based on this study, it is necessary to develop a health program that can reduce the job stress of the subject and solve the job stress healthily.
The purpose of this study was to investigate the daily life experiences of medical students and to explore gender differences in these experiences using the Experience Sampling Method (ESM) as the method. The instrument, the Experience Sampling Form (ESF), consisted of questions on the external and internal experiences of the respondents. Data were collected from 2,035 ESFs by 91 students (male=52, female=39) at three medical schools for one week. The data was analyzed using the statistical tests of the t-test and ${\chi}^2$ test. Activity places were significantly different by gender (${\chi}^2=16.576$, p=.001). Males spent more time in learning places such as schools, libraries, etc., whereas females spent their time in personal places, including their homes, dormitories, etc. Males undertook more learning activities than did females, and females undertook more social/leisure activities and basic life activities than did male students (${\chi}^2=18.753$, p=.001). They were in a learning place and performing learning activities. There were significant perceptual differences between males and females about their flow levels, competency levels, and difficulty levels, based on the activity type. These results can help us to understand the daily lives of medical students and can be useful in developing counseling programs and educational activities for students.
This study utilized the raw data from the Community Health Survey (2023) to compare differences in body function, activity, participation, environment, personal factors, and suicidal ideations between elderly individuals aged 65 and older living alone and those living with families in Korea. The study subjects consisted of 80,618 elderly individuals aged 65 and older. Cross-tabulation analysis χ2-test), independent sample t-test, and logistic regression analysis were conducted. The results indicated that for both elderly individuals living alone and those living with families, age(p<.001), smoking(p<.001), stress(p<.001), depression experience(p<.001), and falls experiences(p<.001) were risk factors that increased suicidal ideations. Conversely, educational level(p<.05), income level(p<.001), subjective health status(p<.001), social participation(p<.001), economic activity(p<.001), community environment(p<.001), and social relationships were protective factors that reduced suicidal ideations. These findings demonstrate that demographic characteristics and individual health status significantly influence suicidal ideation in the elderly, while social factors contribute to a decrease in suicidal ideation. Furthermore, considering the differences found between elderly individuals living alone and those living with families regarding hypertension and gender, differentiated interventions for suicide prevention are necessary.
Doshi, Dolar;Reddy, B Srikanth;Karunakar, P;Deshpande, Kopparesh
Asian Pacific Journal of Cancer Prevention
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제16권13호
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pp.5415-5420
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2015
Background: The present study was designed to ascertain knowledge about HPV, cervical cancer (CC) and the Pap test among female dental students of Panineeya Institute of Dental Sciences and Hospital, Hyderabad, India. Materials and Methods: A self-administered questionnaire covering demographic details, knowledge relating to human papilloma virus (HPV) (8 items), cervical cancer (4 items) and the Pap smear (6 items) was employed. Responses were coded as "True, False and Don't Know". Mean and standard deviation (SD) for correct answers and levels of knowledge were determined. Results: Based on the year of study, significant differences in knowledge of HPV werenoted for questions on symptoms (p=0.01); transmission from asymptomatic partners (p=0.002); treatment with antibiotics (p=0.002); start of sexual activity (p=0.004); and recommended age for HPV vaccination (p=0.01). For knowledge regarding CC, significance was observed for the age group being affected (p=0.008) and symptoms of the disease in early stages (p=0.001). Indications for Pap smear tests like symptoms' of vaginal discharge (p=0.002), marital status (p=0.01) and women with children (p=0.02) had significant difference based on the year of study. Based on religion, transmission of HPV via pregnancy, HPV related diseases except CC and preventive measures except condom use and oral contraceptives showed significant differences. However, significant variation with religion was observed only for two preventive measures of CC (Pap test; p=0.004) and HPV vaccination (p=0.003). Likewise, only the frequency of Pap test showed a significant difference for religion (p=0.001). Conclusions: This study emphasizes the lack of awareness with regard to HPV, CC and screening with pap smear even among health professionals. Hence, regular health campaigns are essential to reduce the disease burden.
PURPOSE: This examined the effects of a sling exercise based on music on the cognition, physical performance of patients with dementia. METHODS: Thirty subjects with dementia volunteered to participate in this study. All subjects were allocated randomly to either the experimental group or control group, with 15 subjects in each group. All subjects underwent the exercise program for an average of 60 minutes per day for 16 weeks. The experimental group performed sling exercise based on music, and the control group performed the general exercise program. Assessments were made using the Korean version of mini-mental state examination (MMSE-K), 10 m walk test (10MWT), Tinetti mobility test (TMT), and Katz's Index of Independence in activity daily living (KIIADL) to detect changes in the cognitive level and physical performance before and after the 16-week training period. A paired t-test was conducted to compare the within-group change before and after the intervention. An independent t-test was performed to compare the between-group difference. The statistical significance level was set to α=.05 for all variables. RESULTS: The experimental group showed significant within-group changes in the MMSE-K, 10MWT, TMT, and KIIADL (p<.05). The control group showed a significant change in only the KIIADL (p<.05). A significant difference was observed between the experimental group and the control group regarding the change in MMSE-K and KIIADL after the interventions (p<.05). CONCLUSION: A music-based sling exercise program effectively improves cognition, physical performance, and ADL in patients with dementia. Further studies with a wider range of subjects and scientific equipment will be needed to strengthen the results of this study.
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