• Journal of Life Science
• /
• v.17 no.11
• /
• pp.1587-1592
• /
• 2007

Locus control region (LCR) is a cia-acting element which regulates the transcription of genes in developmental stage and/or tissue-specific pattern. Typically, LCR consists of several DNase I hypersensitive sites (HSs), where the binding motifs for transcriptional activators are present. The binding of activators to the HSs recruits chromatin modifying complexes to the LCR, opening chromatin structure and modifying histones covalently through the locus. LCR forms close physical contact with target gene located at a distance by looping away intervening region. In addition, non-coding RNA is transcribed from LCR toward target genes in continuously acetylated active domain. These structural and functional features of LCR suggest that the LCR plays many roles in chromatin activation and transcriptional regulation.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.30 no.6
• /
• pp.438-444
• /
• 2019

In this paper, we proposed a 16-element array antenna design to improve signal detection performances. The array antenna characteristics, such as mutual coupling, pattern deviation, and half power beamwidth of the active element, were examined to obtain an optimal spacing between individual elements. The single element of the array antenna consists of an indirect feed using L-shaped feed and shorted radiating patch to achieve a broadband operation. Root mean square(RMS) errors based on the incident angle of the signal were calculated to verify the signal detection performance of the proposed antenna. The results demonstrate that the proposed array antenna with optimal spacing is suitable for detecting interference signals with low RMS error.

• Steel and Composite Structures
• /
• v.37 no.6
• /
• pp.663-678
• /
• 2020

This paper proposes a novel topology optimization method generating multiple materials for external linear plane crack structures based on the combination of IsoGeometric Analysis (IGA) and eXtended Finite Element Method (X-FEM). A so-called eXtended IsoGeometric Analysis (X-IGA) is derived for a mechanical description of a strong discontinuity state's continuous boundaries through the inherited special properties of X-FEM. In X-IGA, control points and patches play the same role with nodes and sub-domains in the finite element method. While being similar to X-FEM, enrichment functions are added to finite element approximation without any mesh generation. The geometry of structures based on basic functions of Non-Uniform Rational B-Splines (NURBS) provides accurate and reliable results. Moreover, the basis function to define the geometry becomes a systematic p-refinement to control the field approximation order without altering the geometry or its parameterization. The accuracy of analytical solutions of X-IGA for the crack problem, which is superior to a conventional X-FEM, guarantees the reliability of the optimal multi-material retrofitting against external cracks through using topology optimization. Topology optimization is applied to the minimal compliance design of two-dimensional plane linear cracked structures retrofitted by multiple distinct materials to prevent the propagation of the present crack pattern. The alternating active-phase algorithm with optimality criteria-based algorithms is employed to update design variables of element densities. Numerical results under different lengths, positions, and angles of given cracks verify the proposed method's efficiency and feasibility in using X-IGA compared to a conventional X-FEM.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.30 no.3
• /
• pp.202-208
• /
• 2019

In this study, an active element pattern (AEP) of a printed dipole was analyzed in 1D and 2D arrays. First, an AEP of the printed dipole was obtained using the simulation in the 2D infinite array. The scan blindness in the 2D array occurred in the E-plane direction at around ${\pm}36^{\circ}$; however, it was barely observed in the 1D array. To analyze the cause of the scan blindness in the 2D array, the dispersion properties of a unit cell was obtained and compared with the scan blindness by frequency change. The difference between the scan blindness of the 1D and 2D arrays was clarified using the comparison of the Q value in the unit cell in the 1D and 2D arrays. Then, the coupling of the electric field in the E-plane direction was observed when nine elements were separated between the two ports in a linearly arranged dipole structure. Finally, the printed dipole array was fabricated, and an AEP was measured for the $11{\times}1$ and $11{\times}3$ sub arrays. The proposed theory was verified using these observations and by comparison with the simulation results.

• Journal of the Semiconductor & Display Technology
• /
• v.22 no.2
• /
• pp.30-34
• /
• 2023

Since dishing in the CMP process is a major factor that hinders the uniformity of the semiconductor thin film, many studies have focused this issue to improve the non-uniformity of the film due to dishing. In the metal layer, the dishing mainly occurs in the central part of the metal due to a difference in a selection ratio between the metal and the dielectric, thereby generating a step on the surface of the metal layer. Factors that cause dishing include the shape of the thin film, the chemical reaction of the slurry, thermal deformation, and the rotational speed of the pad and head, and dishing occurs due to complex interactions between them. This study analyzed the stress generated on the metal layer surface in the CMP process using ANSYS software, a commercial structure analysis program. The stress caused by the vertical load applied from the pad was analyzed by changing the area density and line width of the dummy metal. As a result of the analysis, the stress in the active region decreased as the pattern density and line width of the dummy metal increased, and it was verified that it was valid compared with the previous study that studied the dishing according to the dummy pattern density and line width of the metal layer. In conclusion, it was confirmed that there is a relationship between dishing and normal stress.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.21 no.12
• /
• pp.1380-1393
• /
• 2010

This paper presents a design, fabrication and the test results of planar active electronically scanned array(AESA) radar prototype for airborne fighter applications using transmit/receive(T/R) module hybrid technology. LIG Nex1 developed a AESA radar prototype to obtain key technologies for airborne fighter's radar. The AESA radar prototype consists of a radiating array, T/R modules, a RF manifold, distributed power supplies, beam controllers, compact receivers with ADC(Analog-to-Digital Converter), a liquid-cooling unit, and an appropriate structure. The AESA antenna has a 590 mm-diameter, active-element area capable of containing 536 T/R modules. Each module is located to provide a triangle grid with $14.7\;mm{\times}19.5\;mm$ spacing among T/R modules. The array dissipates 1,554 watts, with a DC input of 2,310 watts when operated at the maximum transmit duty factor. The AESA radar prototype was tested on near-field chamber and the results become equal in expected beam pattern, providing the accurate and flexible control of antenna beam steering and beam shaping.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.30 no.6
• /
• pp.467-478
• /
• 2019

This paper describes the development and measurement results of a wide-band planar active phase array antenna system for an electronic warfare jamming transmitter. The system is designed as an $8{\times}8$ triangular lattice array using a $45^{\circ}$ slant wide-band antenna. The 64-element transmission channel is composed of a wide-band gallium nitride(GaN) solid state power amplifier and a gallium arsenide(GaAs) multi-function core chip(MFC). Each GaAs MFC includes a true-time delay circuit to avoid a wide-band beam squint, a digital attenuator, and a GaAs drive amplifier to electronically steer the transmitted beam over a ${\pm}45^{\circ}$ azimuth angle and ${\pm}25^{\circ}$ elevation angle scan. Measurement of the transmitted beam pattern is conducted using a near-field measurement facility. The EIRP of the designed system, which is 9.8 dB more than the target EIRP performance(P), and the ${\pm}45^{\circ}$ azimuth and ${\pm}25^{\circ}$ elevation beam steering fulfill the desired specifications.

• The Research Journal of the Costume Culture
• /
• v.23 no.4
• /
• pp.595-603
• /
• 2015

The influence of Japonism, which is the post-mid-$19^{th}$ century phenomenon of appreciating and preferring the Japanese style that manifested all across Western art, started to grow as a result of the active open-door policy of Japan at this time. As all areas of Japanese arts and culture, such as paintings, sculptures and theater plays, influenced Europe and America, this influence developed into a cultural phenomenon that was reflected even in fashion. The characteristic elements of the kimono first expanded from Paris and showed a similar silhouette to that of the traditional kimono in the early $20^{th}$ century, but towards the middle and the end of the century, kimono sleeves that were connected as one piece without a connecting seam line between the sleeve and bodice started to appear. The foundation of this research focuses on the design characteristics of kimono sleeves that can be seen in $20^{th}$-century fashion, and five varying kimono sleeve jackets and coats based on these formative characteristics were designed. Each design had a gusset design added, which improved the external and mobility problems inherent in kimono sleeve patterns, while at the same time serving as a proposal for new design element applications. Additionally, through various changes to and attempts at designs using the kimono sleeve as a limiting factor, new design possibilities were explored.

• Journal of the Korean Society of Costume
• /
• v.60 no.6
• /
• pp.11-22
• /
• 2010

Purpose: The purpose of this study is to develop golf wear textile design, produce simulation and samples, and create original designs using geometric patterns. Significance: If modern people's trend to pursue well-being is be associated with healthy and active lifestyle and the design which combines a sport sense into artistic image appears in golf wear, it is a very significant effort to settle the role of sport as a mega trend. Contents: This study examined the general concept of geometric patterns and the situation and characteristics of women's golf wear. Finally, the design and simulation of gold wear textile were proposed. Study Instruments: For theoretical research, articles, books, literatures, and Internet materials published at home and abroad were reviewed and collected. For empirical research, a dot, a stripe(a line), a square, and an oval were selected and simulation was tested visually after the development of textile designs. Finally it was directly produced and golf wear design was developed. Photoshop CS 3 and Wacom intuos 3 were used as a general-purpose program and hardware respectively. DTP printing was used for sample work. Based on research results, geometric patterns range broadly and diversely from prehistoric remains and relics to contemporary art, design, architecture, and fashion. It is a unique formative element with value and attraction as the infinite object of inquiry beyond an area and the times. The combination of geometric patterns with art touch could complement the rigidity of design. It contributed to the perception of important role of art in the design area, namely, the importance of design containing artistry.

• Molecules and Cells
• /
• v.43 no.4
• /
• pp.331-339
• /
• 2020

Genetic modifications in noncoding regulatory regions are likely critical to human evolution. Human-accelerated noncoding elements are highly conserved noncoding regions among vertebrates but have large differences across humans, which implies human-specific regulatory potential. In this study, we found that human-accelerated noncoding elements were frequently coupled with DNase I hypersensitive sites (DHSs), together with monomethylated and trimethylated histone H3 lysine 4, which are active regulatory markers. This coupling was particularly pronounced in fetal brains relative to adult brains, non-brain fetal tissues, and embryonic stem cells. However, fetal brain DHSs were also specifically enriched in deeply conserved sequences, implying coexistence of universal maintenance and human-specific fitness in human brain development. We assessed whether this coexisting pattern was a general one by quantitatively measuring evolutionary rates of DHSs. As a result, fetal brain DHSs showed a mixed but distinct signature of regional conservation and outlier point acceleration as compared to other DHSs. This finding suggests that brain developmental sequences are selectively constrained in general, whereas specific nucleotides are under positive selection or constraint relaxation simultaneously. Hence, we hypothesize that human- or primate-specific changes to universally conserved regulatory codes of brain development may drive the accelerated, and most likely adaptive, evolution of the regulatory network of the human brain.