• Title/Summary/Keyword: Action Content

Search Result 666, Processing Time 0.021 seconds

THE IMPORTANCE OF BICARBONATE-BUFFER ON CARDIAC FUNCTION: Contractility, Membrane Potentials and ATP Content of Isolated Atria in the Absence of External Buffers (심장기능(心臟機能)에 미치는 Bicarbonate-Buffer의 중요성(重要性) : Buffer 제거(除去)에 의(依)한 유리심방(遊離心房)의 수축성(收縮性), 막전위(膜電位) 및 ATP 함량(含量)의 변동(變動))

  • Ko, Kye-Chang;Han, Dae-Sup;Jung, Jee-Chang
    • The Korean Journal of Pharmacology
    • /
    • v.8 no.2
    • /
    • pp.63-69
    • /
    • 1972
  • The effects of omission of buffers from Krebs-Ringer medium on contractile activity, membrane potentials and ATP content of electrically stimulated isolated rat atria were investigated. 1) Contractile status: A rapid and marked depression of the contractile activity of atria occurred when buffer-free medium was substituted for the normal Krebs-Ringer medium. 2) Electrical status: The omission of buffers from medium did not alter the resting or action potential magnitudes of atria. However, the action potential duration was on initial increase followed by a decrease in the buffer-free medium. 3) ATP concentration: The omission of buffers from medium resulted in a marked decrease in the ATP levels of atria. It has been also found in the present study that bicarbonate buffer plays an important role for the maintenance of the contractility and ATP levels of the heart. The contractile depression by the omission of buffers was not directly associated with electrical alterations in resting or action potentials of the heart. In the absence of bicarbonate-buffer, glucose no longer plays to maintain the contractile activity and the ATP levels of rat atria.

  • PDF

EFFICACY EVALUATION OF THE WHITENING COSMETICS USING MELANOGENESIS INHIBITION ASSAY COSMETICS IN B-16 MELANOMA CELL

  • S. J. Yang;S. J. Jang;Park, S. S.;J. Y. Jang;K. H. Son;Lee, J. P.;Lee, K. S.;M. Y. Heo;Kim, Y. O.
    • Proceedings of the SCSK Conference
    • /
    • 2003.09b
    • /
    • pp.544-544
    • /
    • 2003
  • We investigated the inhibitory effect of whitening materials with growth factor or alone on melanomas derived from Human (B-16) and mouse (SK-MEL-31) using melanin content. Melanin content was determined by the absorbance value at 470nm per cells. we used the growth factors known as activators of Adenylate cyclase, Protein kinase C and tyrosine kinase pathway separately. In addition, we compared the action of UV-induced with non-biological growth factor with whitening materials in melanomas derived from Human and mouse. The results showed that the aspect of inhibitory effect of whitening materials on B16 and SK-MEL-31 was not different. And, the action of each growth factor involved in the differentiation and proliferation of melanoma on the inhibition of melanogenesis in B-16 and SK-MEL-31 using whitening agents showed no difference. Also, The action of UV -induced and non-biological growth factors didn't exhibit different pattern on the effect of whitening agent in B-16 and SK-MEL-31.

  • PDF

Analgesic Action of p-Methoxycinnamic acid. (p-Methoxycinnamic Acid의 진통작용)

  • 우원식
    • YAKHAK HOEJI
    • /
    • v.9 no.3_4
    • /
    • pp.31-33
    • /
    • 1965
  • In the previous papers, it was reported that p-methoxycinnamate showed good antipyretic action when tested on the typhoid-vaccinated rabbits and decreased the ascorbic acid content of the adrenals of rats like other wellknown antipyretics. In the present work, it was shown that p-methoxycinnamic acid exhibited marked analgesic properties. The method employed for testing analgesic effect was modification of that described by Woolfe and Macdonald. Of mice which had been trained and jumped out within 5 seconds on the hot plate of $59{\deg}$, the reaction time was prolonged by subcutaneous injection of its sodium salt aqueous solution. Mean responses were proved to increase linearly with the log doses (from doses 160 mg to 500 mg/kg).

  • PDF

The effect of several cholanic acid derivatives on bile secretion (담즙산류가 담즙배출에 미치는 영향)

  • 홍사욱;박대성;한덕룡;이종철;홍사석
    • YAKHAK HOEJI
    • /
    • v.16 no.4
    • /
    • pp.176-179
    • /
    • 1972
  • The bile secretion was accelerated generally by the administration of all derivatives tested: chemodeoxycholate, deoxycholate, cholate, dehydrocholate, 7-ketochenodeoxycholate, and 3, 7-diketochenodeoxycholate in decreasing order. Bile acids content in bile from animals administered with cholate was increased, however, other derivatives did not alter the contents of bile acids and bilirubin. In view of pharmacological point, all derivatives have hydrocholeretic action, however, only cholate exhibits typical choleretic action.

  • PDF

Immunological ObservatioIn on Gandidiasis (Candida증(症) 발생(發生)의 면역학적(免疫學的) 기전(機轉)에 관(關)한 연구(硏究))

  • Kim, Hong-Sik
    • The Korean Journal of Mycology
    • /
    • v.6 no.2
    • /
    • pp.15-18
    • /
    • 1978
  • The study was performed to investigate the inhibitory action on the growth rate of Candida albicans under the various immunological conditions, Candida albicans was grown in broth media containing 0.1ml. (in total broth volume 4.0ml.) of normal human serum, diabetic patient serum, albumin solution, artifical bulla content and nutrient solution as control subject. The inhibitory action of Candida albicans was indicated by mesurement of transparency rate with use of the spectrophotometer. The results are as follows: 1. Normal human serum shows inhibitory effect on the growth of the candida distinctly. 2. Albumin solution reveals almost similar to that of the effect of normal human serum. 3. Artificial bulla content which obtained by irradiation of ultraviolot ray after application of 1% 8-Methoxy-psolaren cream and the diabetic patient serum shows reduction of inhibitory effect as compared with that of the normal human serum. 4. It is estimated that the titer of negative effect of diabetic patient serum is not related with the variation of immunoglobulin titer in patient serum.

  • PDF

A Comparative Study on Korean and American High School Home Economics Textbooks Based on Habermas's Three Systems of Action: Focusing on the Learning Objectives and Activities (Habermas의 세 행동체계의 관점에서 본 한국과 미국의 고등학교 가정교과서 식생활 단원의 학습목표와 활동과제 비교 연구)

  • Choi, Seong-Youn;Chae, Jung-Hyun
    • Journal of Korean Home Economics Education Association
    • /
    • v.32 no.1
    • /
    • pp.107-125
    • /
    • 2020
  • The purpose of this study was to analyze the dietary life units of Korean and American high school home economics textbook according to Habermas's three systems of action and to find out how the three systems of action are reflected in the learning objectives and activity tasks of the textbook. To achieve this purpose, this study analyzed the learning objectives and activity tasks of the dietary life units in the textbooks of 'technology & home economics' and 'home economics science' in Korea, and 'succeeding in life and career' in America using a content analysis technique based on Habermas's three systems of action. In analyzing the content, each learning objective or activity was matched with one of the three systems of action by examining the context. In some cases, two or more systems of actions were integrated in one activity. This is a case where a series of learning tasks that involve different action system were grouped into one. The numbers of learning objectives and activities of the units of 'technology & home economics', 'home economics science' textbooks of Korean high schools and 'succeeding in life and career' dietary life of American high schools were 3, 26, and 248, respectively. In Korean textbooks, the percentage of communicative action was highest among the three systems, that is, 66.7% for 'technology & home economics' textbooks and 50% for 'home economics science' textbooks. In comparison technical action was the highest in American textbooks at 66.5%. Activities related to technical action included cooking, conducting research on health and food, or conducting experiments. The activities related to communicative action included role play related to health and table manners, or writing reports after conducting surveys or interviewing professionals. The activities related to emancipative action were to social participation activities such as service project in relation to health and food, or to find problems that occur in dietary life and think about be best solution through practical reasoning.

An Action Research to Improve Fundamental Nursing Practice Course: Designing College Courses Model (수업디자인 모형을 적용한 기본간호학실습 수업 개선의 실행연구)

  • Kim, Heeyoung;Kim, Yun-Hee
    • Journal of Korean Academy of Fundamentals of Nursing
    • /
    • v.22 no.2
    • /
    • pp.169-179
    • /
    • 2015
  • Purpose: The purpose of this study was to improve the quality of fundamental nursing practice course. Methods: Participants were 132 students who took the fundamental nursing practice course at D university in N city. The study included processes of planning, action, observation, and reflection. Quantitative data were analyzed using SPSS 20.0 program and qualitative data were evaluated through content analysis. Results: The 12-step designing college courses model by Fink was applied in the planning. In the acting stage, the course was conducted according to the instruction in designing the course, students wrote reflective journals and the professor gave feedback to the reflective journal and the class observation journal was used for lessons. In the observation stage, the course evaluation was surveyed and analyzed, evaluations were positive with 47.1% of students positively evaluating the teaching strategy. In the reflecting stage, outcomes in course improvement were reflected on and, the number of students at the lower level-of-achievement decreased. Conclusion: Action research was a useful research method that could capture the quality improvement process in college courses. Expression of effort and passion to improve quality of education through action research in various ways and to share quality improvement strategies for nursing education are important.

A Coordinate System of Classification for Effective Visualizations of Story Properties (스토리 창작 특성의 효과적 가시화를 위한 분류 좌표계 연구)

  • Kim, Myoung-Jun
    • Journal of Digital Contents Society
    • /
    • v.18 no.6
    • /
    • pp.1119-1125
    • /
    • 2017
  • Genres and actions of stories can be used to classify stories, and used effectively as well for visualizing story properties. This paper proposes a Genre-Action coordinate system for visualizing story property data in 2-dimension that has similarities between the genre and action items along the axes, i.e. a property of spatial continuum. With the proposed Genre-Action coordinate system we found that the genre and action items in the axes are arranged according to their similarities and we were able to achieve a spatially meaningful visualization of story properties where the related data form clusters.

A Prediction of Shear Strength Using Arch Models in Reinforced Concrete Beams without Web Reinforcement (아치모델을 이용한 복부보강이 안된 철근 콘크리트 보의 전단강도 산정)

  • 김대중
    • Magazine of the Korea Concrete Institute
    • /
    • v.10 no.6
    • /
    • pp.233-240
    • /
    • 1998
  • A rational expression, developed to predict the shear strength of reinforced concrete beams, is derived from the relationship between shear and the rate of change of bending moment along a beam coupled with experimental findings for the arch action. The proposed ultimate shear strength equation, arising from analytical premises and then calibrated with experimental data, is a similar form to the ACI 318 equation derived mainly from empirical approach. The proposed equation depends on the concrete compressive strength, amount of longitudinal steel content, and the shear span-to-depth ratio, and rationally reflects the shear resistance mechanism of combined beam action and arch action in reinforced concrete beams. The proposed equation applied to existing test data and the results were compared with those predicted by the ACI 318 equation and the Zsutty's equation.

Development of Content Structure Focusing on Three Systems of Action for the 2009 Revised Current Home Economics Curriculum (2009 개정 현행 가정과 교육과정을 위한 세 행동체계 중심의 내용체계 개발)

  • Ju, Sueun;Yoo, Taemyung
    • Journal of Korean Home Economics Education Association
    • /
    • v.28 no.2
    • /
    • pp.1-19
    • /
    • 2016
  • The purpose of this study was to design curriculum content structure integrating three systems of actions for 2009 revised current home economics curriculum. For the development of content structure and content elements, a development team of two home economics scholars, a cooperating team of three home economics teachers, and an expert team of 15 home economics teachers and professors were organized. Phase 1 of curriculum development was developed by integrating three systems of actions with traditional home economics content areas of clothing, food, housing, consumption, and family by the development team. It is examined by the cooperating team and in phase 2 is recommended to build matrix of units of the current curriculum and the three systems of actions. The final phase of curriculum development illustrated a content structure integrating the sub-units of 2009 revised current curriculum and the three systems of action following the expert group's professional opinion.