• Title/Summary/Keyword: ATP system

Search Result 328, Processing Time 0.04 seconds

Effect of L-carnitine on Field Potential and ATP-dependent K+ Channel of Rat Cardiac Muscles (L-carnitine 투여가 흰쥐의 심근 Field Potential과 ATP-dependent K+ channel에 미치는 영향)

  • Kim, Jee-Youn;Sim, Young-Je;Chang, Hyun-Kyung;Kim, Chang-Ju
    • Korean Journal of Exercise Nutrition
    • /
    • v.13 no.1
    • /
    • pp.15-21
    • /
    • 2009
  • Ergogenic aids are substances, devices, and practices that enhance an individual's energy use and production, and recovery from fatigue. L-carnitine increases enhance performance and aerobic capacity by stimulating lipid oxidation in muscle cells during long term exercise. L-carnitine is a well known and widely used ergogenic aid. In the present study, the effect of L-carnitine at concentrations of 100 nM, 1 μM, 10 μM, and 100 μM on the amplitude of field potential in rat cardiac muscle slices was measured using multi-channel extracellular recording (MED 64) system. In the present result, L-carnitine was shown to enhance field potential as a does-dependent manner. The increasing effect of the L-carnitine on field potential was not affected by application of the glibenclamide, an ATP-dependant K+ channel antagonist. The increasing effect of L-carnitine on field potential was suppressed by application of the diazoxide, an ATP-dependent K+ channel agonist. Present data show that L-carnitine potentiates field potentials by inhibition on ATP-dependant K+ channel in cardiac muscles. The enhancing effect of the L-carnitine on the field potential in cardiac muscles can be suggested as one of the underlying mechanism of ergogenic aid of the L-carnitine.

Evaluation of Hygienic Status of University Foodservice Operation using ATP bioluminescence Assay (ATP bioluminescence Assay를 이용한 대학 급식시설의 위생상태 평가에 관한 연구)

  • 박영숙
    • Korean journal of food and cookery science
    • /
    • v.16 no.2
    • /
    • pp.195-201
    • /
    • 2000
  • An investigation was conducted to evaluate the hygienic status of university foodservice operation by using conventional swabbing technique plus standard plate count and ATP bioluminescence assay. The results of the study were as follows: 1) For all kitchen boards, knives, feeding trays, and dish towels tested, there was an overall agreement at 84.7% level between the results obtained using ATP bioluminescence and plate count when using a pass/fail cut-off of 3$\times$ control values for ATP assay and 40 CFU(colony forming unit)/㎠ for plate count. 2) The agrement rate between ATP assay and standard plate count was 87.5% for the samples before use, 29.2% for those during use, and 42.7% for those after cleaning and sanitizing. 3) The plate counts of three university foodservice operations for kitchen board, kitchen knife, feeding tray and dish towel were within the acceptable limits when tested before using. However, none of them were within the acceptable limits when tested during using and after cleaning and sanitizing. 4) Above results suggested that an immediate action needs to be taken to reduce the potential danger of cross-contamination and also effective sanitary control methods needs to be developed to improve the sanitary condition.

  • PDF

The Study for Tilting Train Adaptation of ATP Onboard System (ATP 차상장치의 틸팅열차 적용에 대한 연구)

  • Baek, Jong-Hyen;Kim, Yong-Kyu;Shin, Duck-Ho;Lee, Kang-Mi
    • Proceedings of the KIEE Conference
    • /
    • 2008.07a
    • /
    • pp.1012-1013
    • /
    • 2008
  • 경부고속철도의 개통과 함께 서울-부산 간 운행시간이 새마을호 기준 4시간 30분에서 2시간으로 단축되는 등 획기적인 시간 절감을 이루었으나 이는 고속철도가 운행되는 지역에 국한된 것이다. 이에 고속철도 비 수혜지역의 운행시간 단축을 위해 기존선 속도향상이 요구되며, 이러한 목적으로 한국철도기술연구원에서는 틸팅열차를 개발하여 시운전 10만Km를 목표로 시험운행중이다. 또한 한국철도공사에서는 이와 유사한 목적으로 기존선 신호시스템인 ATS 시스템을 차상신호시스템(ATP)으로 개량하는 사업이 추진되고 있다. 현재 틸팅열차에는 기존의 ATS(자동열차정지장치) 차상장치만을 장착하여 차량의 성능 확인을 위한 시험 및 시운전을 우선적으로 추진하고 있는 상태이며 이러한 ATS 차상장치는 160km/h 이하의 속도에서만 본연의 기능이 유지되고, 그 이상의 속도에서는 현실적으로 사용이 어렵기 때문에 틸팅열차의 목표속도인 200km/h에서 적합하게 시험하기 위해서는 적합하지 않다. 따라서 한국철도공사에서 추진하고 있는 ATP 구축사업의 지상설비와 연계될 수 있는 ATP 차상장치를 설치하여 시험을 하여야 한다. 본 논문에서는 이를 위하여 ATP 차상장치의 틸팅열차 적용에 대한 연구를 추진한 결과를 발표하고자 한다.

  • PDF

Evidence for Adenosine Triphosphate (ATP) as an Excitatory Neurotransmitter in Guinea-Pig Gastric Antrum

  • Kang, Tong-Mook;Xu, Wenxie;Kim, Sung-Joon;Ahn, Seung-Cheol;Kim, Young-Chul;So, In-Suk;Park, Myoung-Kyu;Uhm, Dae-Yong;Kim, Ki-Whan
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.3 no.2
    • /
    • pp.165-174
    • /
    • 1999
  • We explore the question of whether adenosine 5'-triphosphate (ATP) acts as an excitatory neurotransmitter in guinea-pig gastric smooth muscle. In an organ bath system, isometric force of the circular smooth muscle of guinea-pig gastric antrum was measured in the presence of atropine and guanethidine. Under electrical field stimulation (EFS) at high frequencies (>20 Hz), NO-mediated relaxation during EFS was followed by a strong contraction after the cessation of EFS (a 'rebound-contraction'). Exogenous ATP mimicked the rebound-contraction. A known $P_{2Y}-purinoceptor$ antagonist, reactive blue 2 (RB-2), blocked the rebound-contraction while selective desensitization of $P_{2Y}-purinoceptor$ with ${\alpha},{\beta}-MeATP$ did not affect it. ATP and 2-MeSATP induced smooth muscle contraction, which was effectively blocked by RB-2 and suramin, a nonselective $P_2-purinoceptor$ antagonist. Particularly, in the presence of RB-2, exogenous ATP and 2-MeSATP inhibited spontaneous phasic contractions, suggesting the existence of different populations of purinoceptors. Both the rebound-contraction and the agonist-induced contraction were not inhibited by indomethacin. The rank orders of agonists' potency were 2-MeSATP > ATP ${ge}$ UTP for contraction and ${\alpha},{\beta}-MeATP\;{\ge}\;{\beta},{\gamma}-MeATP$ for inhibition of the phasic contraction, that accord with the commonly accepted rank order of the classical $P_{2Y}-purinoceptor$ subtypes. Electrical activities of smooth muscles were only slightly influenced by ATP and 2-MeSATP, whereas ${\alpha},{\beta}-MeATP$ attenuated slow waves with membrane hyperpolarization. From the above results, it is suggested that ATP acts as an excitatory neurotransmitter, which mediates the rebound-contraction via $P_{2Y}-purinoceptor$ in guinea-pig gastric antrum.

  • PDF

A Study on a Multi-path ATP Protocol at Ad-hoc Networks (Ad-hoc 네트워크에서 다중경로를 지원하는 ATP 프로토콜에 대한 연구)

  • Lee, Hak-Ju;Jang, Jae-Shin;Lee, Jong-Hyup
    • Journal of the Korea Society for Simulation
    • /
    • v.18 no.3
    • /
    • pp.123-131
    • /
    • 2009
  • Wireless networks have several unique features : node mobility, restricted bandwidth, time-variable bandwidth, large latency, and high bit error rates time due to channel fading. These features at wireless networks intend to decrease the performance TCP protocols are used in wireless networks. Lots of studies have been done for finding appropriate wireless transport protocols for current wireless communications. However, related studies have not provided good performance or some protocols have a good performance only in specific circumstances. Thus, these are not suitable for general wireless circumstance. Therefore, we propose a new wireless transport protocol which provides better performance than the previous ones. And we'd like to solve a problem that previous protocols cannot maintain their connections even though they have multiple paths until another path is successfully set up. To solve these problems, a new protocol ATP-M is proposed which is designed on already known TCP-M and ATP protocols. With NS-2 computer simulation, it is shown that this newly proposed protocol has better system throughput than TCP, TCP-M and ATP protocols.

Effect of quaternary ammonium compounds on microbial contamination levels in dental clinics (치과 진료실의 미생물 오염도에 대한 4차 암모늄 화합물의 효과)

  • Baik, Sae Yun;Park, YounJung;Choi, Seung Ho;Kim, Hee Jae;Kim, Seong Taek
    • Journal of Dental Rehabilitation and Applied Science
    • /
    • v.36 no.1
    • /
    • pp.55-60
    • /
    • 2020
  • The aim of this study was to investigate the change of microbial contamination levels in the different areas and at the different time points after application of a quaternary ammonium compound (QAC) that has mechanical antimicrobial effect. The microbial contamination levels were measured in three different areas; unit chair handle, spit sink area and hand piece holder at different time points using adenosine triphosphate (ATP) monitoring system and ATP surface test kit. Hand piece holder showed the highest level of microbial contamination. In most of the clinics, QAC significantly reduced the levels of microbial contamination, and maintained antimicrobial activity for 4 to 6 months. QAC may be used effectively in dental clinics due to the duration of antimicrobial effect and the minimal exposure of chemicals and further studies are needed with large sample size.

Evauation of Hygienic Status of High School Foodservice using ATP Bioluminescence Assay & Microorganism Test Strips (ATP Bioluminescence와 간이미생물배지를 이용한 고등학교 급식시설의 위생상태 조사연구)

  • Jang, Jae-Seon;Hwang, Seong-Hee
    • The Korean Journal of Food And Nutrition
    • /
    • v.28 no.5
    • /
    • pp.918-925
    • /
    • 2015
  • An investigation was conducted to evaluate the hygienic status of 33 high school foodservice systems in Yongin city by using hygiene management guide checklist, ATP bioluminescence assay and microbe inspection petrifilm (APC, coliform group, Staphylococcus aureus) of food utensils during use. The 22 hygiene management guide checklist items about facilities, personal hygiene, food control, distribution, washing and disinfection had good grade but there were some inadequate behaviors on observation. The inspection results showed their sanitary condition met the level B of the recommendation of Korea method, it means sanitary management system get settled but more practical CCP system was needed. ATP bioluminescence assay was conducted on surface of food facilities, ATP ranged 425~2,552 RLU on gloves, 541~70,251 RLU on apron, 1,596~88,490 RLU on working desk, 1,177~263,813 RLU on sterilizer grip, 715~32,814 RLU on sterilizer shelf, 114~619,725 RLU on refrigerator grip, 677~319,007 RLU on refrigerator shelf, 71~196,725 RLU on freezer grip, 1,535~233,375 RLU on freezer shelf. APC ranged $66.7{\pm}29.0CFU$ on freezer grip, $102.1{\pm}35.9CFU$ on refrigerator grip, $45.4{\pm}28.2CFU$ on heating cabinet grip, $58.8{\pm}40.4CFU$ on sterilizer grip, the number of coliform group ranged $5.6{\pm}4.9CFU$ on freezer grip, $9.1{\pm}8.7CFU$ on refrigerator grip, $1.2{\pm}1.1CFU$ on heating cabinet grip, $4.5{\pm}4.4CFU$ on sterilizer grip. S. aureus ranged $8.0{\pm}5.6CFU$ on freezer grip, $12.2{\pm}9.6CFU$ on refrigerator grip, $2.1{\pm}1.6CFU$ on heating cabinet grip, $11.6{\pm}6.4CFU$ on sterilizer grip.

Four Consistency Levels in Trigger Processing (트리거 처리 4 단계 일관성 레벨)

  • ;Eric Hanson
    • Journal of KIISE:Databases
    • /
    • v.29 no.6
    • /
    • pp.492-501
    • /
    • 2002
  • An asynchronous trigger processor (ATP) is a oftware system that processes triggers after update transactions to databases are complete. In an ATP, discrimination networks are used to check the trigger conditions efficiently. Discrimination networks store their internal states in memory nodes. TriggerMan is an ATP and uses Gator network as the .discrimination network. The changes in databases are delivered to TriggerMan in the form of tokens. Processing tokens against a Gator network updates the memory nodes of the network and checks the condition of a trigger for which the network is built. Parallel token processing is one of the methods that can improve the system performance. However, uncontrolled parallel processing breaks trigger processing semantic consistency. In this paper, we propose four trigger processing consistency levels that allow parallel token processing with minimal anomalies. For each consistency level, a parallel token processing technique is developed. The techniques are proven to be valid and are also applicable to materialized view maintenance.

A Rapid Method for Determination of ATP and Its Related Compounds in Dried Fish and Shellfish Products Using HPLC (HPLC에 의한 시판수산건제품의 ATP분해생성물의 신속정량법)

  • LEE Eung-Ho;KOO Jae-Geun;AHN Chang-Bum;CHA Yong-Jun;OH Kwang-Soo
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.17 no.5
    • /
    • pp.368-372
    • /
    • 1984
  • This paper deals with a rapid method for determination of ATP and its related compounds in fish and shellfish products using high performance liquid chromatography(HPLC). The HPLC used is a HPLC/ALC-224 equiped with UV-spectrophotometer (254 nm) as detector and integrator (Yanagimoto system-1000). The column used is a stainless steel tubing ($30.0\;cm{\times}3.9\;mm\;i.d.$) packed with ${\mu}-Bon-dapak\;C_{18}$. A mixture of $1\%$ triethylamine-phosphoric acid(pH6.5) was used as an eluent and the flow rate of the eluent was controlled at 2 ml/min. For the separation of ATP and its related compounds, a standard mixture of ATP, ADP, AMP, IMP, inosine and hypoxanthine was subjected to HPLC under the above mentioned conditions. Six peaks were obtained with retention times within 20 min, and elution order were hypoxanthine, IMP, inosine, AMP, ADP and ATP. But 5'-IMP and 5'-GMP fractions were not separated by this method. In generally, IMP content in boiled-dried fish and shellfish products purchased from the market was comparatively higher than that of other nucleotides. Especially, boiled-dried big eye herring marked higher value in IMP content than other boiled-dried ones. Hypoxanthine and inosine were major components of ATP-related compounds in dried products and seasoned-dried ones. And IMP content in seasoned-dried products was higher than that of dried ones. This fact is suggested that a part of IMP in seasoned-dried ones was derived from flavoring matter (MSG, 5'-IMP and 5'-GMP) which is added during the seasoning treatment.

  • PDF