• 제목/요약/키워드: AR6

검색결과 1,665건 처리시간 0.026초

세신(細辛) 주정(酒錠) 추출물(抽出物)이 LPS로 유발된 RAW 264.7 Cell의 염증 및 항산화 반응에 미치는 영향 (Anti-oxidation and Anti-inflammatory Effect of Asiasari Radix in RAW 264.7 Cells)

  • 이옥진;오민석
    • 한방재활의학과학회지
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    • 제24권3호
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    • pp.99-110
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    • 2014
  • Objectives The purpose of this study was to investigate the Anti-oxidation and anti-inflammatory effects of ethanol extract from asiasari radix (AR) on lipopolysaccharide (LPS)-induced in RAW 264.7 Cells Methods Anti-oxidative effects of AR were measured by scavenging activities of 1,1-diphenyl-2-picryl-hydrazyl (DPPH), 2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and production of reactive oxygen species (ROS) in RAW 264.7 cells. Anti-inflammatory effects of AR were measured by mediators including nitric oxide(NO), interleukin-$1{\beta}$ (IL-$1{\beta}$), interleukin-6 (IL-6), tumor necosis factors-${\alpha}$ (TNF-${\alpha}$) and iNOS, IL-$1{\beta}$, IL-6, TNF-${\alpha}$ mRNA expression in RAW 264.7 cells. Results Total phenolic content was expressed $28.77{\pm}1.67$. DPPH radical Scavenging was increased depend on AR ethanol extract. ABAT radical Scavenging was increased depend on AR ethanol extract. Production of ROS was significantly decreased by AR ethanol extract on concentration of 100 (${\mu}g/ml$). Production of NO was significantly decreased by AR ethanol extract on concentration of $100({\mu}g/ml)$. Production of IL-$1{\beta}$, interleukin-6 and TNF-${\alpha}$ were increased depend on AR ethanol extract. And Production of interleukin-6, TNF-${\alpha}$ were significantly decreased AR ethanol extract. iNOS, IL-$1{\beta}$, IL-6, TNF-${\alpha}$ mRNA expression of RAW 264.7 cells was increased depend on AR ethanol extract. Conclusions According to this study, AR ethanol extract has anti-oxidative and anti-inflammatoy effects.

Pt 박막의 $SF_6/Ar과 Cl_2/Ar4$ 플라즈마 가스와의 표면반응에 관한 연구 (Study on the Surface Reaction of Pt thin Film with $SF_6/Ar and Cl_2/Ar$ plasma gases)

  • 김상훈;주섭열;안진호
    • 한국마이크로전자및패키징학회:학술대회논문집
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    • 한국마이크로전자및패키징학회 2001년도 The IMAPS-Korea Workshop 2001 Emerging Technology on packaging
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    • pp.110-113
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    • 2001
  • ECR(electron cyclotron resonance) 플라즈마 식각 장비를 이용하여 SF$_{6}$/Ar과 Cl$_2$/Ar 플라즈마 가스에 대한 Platinum (이하 Pt) 박막의 식각 특성을 연구하였다. Pt 박막의 경우 Cl$_2$ 가스 혼합물에 대한 식각 특성은 많이 보고가 되어 왔으나 상대적으로 Fluorine 계열의 가스 혼합물에 의한 시각 연구는 미비하였다. 본 연구에서는 SF$_{6}$/Ar과 Cl$_2$/Ar 플라즈마 가스를 이용한 Pt 박막의 식각 특성을 비교 분석하고 각각의 가스와 Pt 박막과의 반응을 분석, 식각 특성을 개선하고자 하였다.

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Resveratrol Inhibits IL-6-Induced Transcriptional Activity of AR and STAT3 in Human Prostate Cancer LNCaP-FGC Cells

  • Lee, Mee-Hyun;Kundu, Joydeb Kumar;Keum, Young-Sam;Cho, Yong-Yeon;Surh, Young-Joon;Choi, Bu Young
    • Biomolecules & Therapeutics
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    • 제22권5호
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    • pp.426-430
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    • 2014
  • Prostate cancer is the most frequently diagnosed cancer. Although prostate tumors respond to androgen ablation therapy at an early stage, they often acquire the potential of androgen-independent growth. Elevated transcriptional activity of androgen receptor (AR) and/or signal transducer and activator of transcription-3 (STAT3) contributes to the proliferation of prostate cancer cells. In the present study, we examined the effect of resveratrol, a phytoalexin present in grapes, on the reporter gene activity of AR and STAT3 in human prostate cancer (LNCaP-FGC) cells stimulated with interleukin-6 (IL-6) and/or dihydrotestosterone (DHT). Our study revealed that resveratrol suppressed the growth of LNCaP-FGC cells in a time- and concentration-dependent manner. Whereas the AR transcriptional activity was induced by treatment with either IL-6 or DHT, the STAT3 transcriptional activity was induced only by treatment with IL-6 but not with DHT. Resveratrol significantly attenuated IL-6-induced STAT3 transcriptional activity, and DHT- or IL-6-induced AR transcriptional activity. Treatment of cells with DHT plus IL-6 significantly increased the AR transcriptional activity as compared to DHT or IL-6 treatment alone and resveratrol markedly diminished DHT plus IL-6-induced AR transcriptional activity. Furthermore, the production of prostate-specific antigen (PSA) was decreased by resveratrol in the DHT-, IL-6- or DHT plus IL-6-treated LNCaP-FGC cells. Taken together, the inhibitory effects of resveratrol on IL-6- and/or DHT-induced AR transcriptional activity in LNCaP prostate cancer cells are partly mediated through the suppression of STAT3 reporter gene activity, suggesting that resveratrol may be a promising therapeutic choice for the treatment of prostate cancer.

$SF_6$-Ar 혼합기체에서의 전리와부착계수 (Ionization and Attachment Coefficients in Mixtures of $SF_6$ and Ar)

  • 김상남;하성철
    • 한국전기전자재료학회논문지
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    • 제14권9호
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    • pp.773-778
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    • 2001
  • In this dissertation the results of the combined experimental and theoretical studies designed to understand and predict the spatial growth and transport coefficients for electrons in SF$_{6}$ and SF$_{6}$-Ar mixtures have described. The ionization and attachment coefficients in pure SF$_{6}$ and SF$_{6}$-Ar mixtures have been calculated over the range of 10$_{6}$ molecule and for Ar atom proposed by other authors. The transport coefficients for electrons in (0.2%)SF$_{6}$-Ar and (0.5%)SF$_{6}$-Ar mixtures were measured by time-of-flight method, and the electron energy distribution function and the parameters of the velocity and the diffusion were determined by the variation of the collision cross-sections with energy. The results obtained in this work will provide valuable information on the fundamental haviors of electrons in weakly ionized gases and the role of electron attachment in the choice of better gases and unitary gas dielectrics or electro negative components in dielectric gas mixtures. gas mixtures.

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MIPv6망에서 안전한 호스트 이동성 지원 방안 (Secure Host Mobility in the Mobile IPv6 Network)

  • 김정주;홍석원
    • 한국정보통신학회:학술대회논문집
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    • 한국해양정보통신학회 2005년도 추계종합학술대회
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    • pp.82-85
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    • 2005
  • 이동 Pv6(MIPv6)를 지원하는 네트워크에서 이동 노드(mobile node)가 새로운 네트워크로 이동했을 때 그 네트워크에서의 엑세스 라우터와 엑세스 포인트(Access Router/Access Point)를 찾아 연결해야 한다. 이때 신뢰할 수 있는 AR과 AP에 연결하지 못할 경우 여러 형태의 공격에 노출된다. 본 논문에서는 SEcure Neighbor Discovery(SEND)에서 사용하는 공개키 기반 RSA 암호화 방식을 응용하여 AR/AP와 MN이 상호 인증할 수 있는 방안을 제시한다.

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SF6/Ar 유도결합플라즈마를 이용한 ZnO 박막의 식각 특성에 관한 연구 (A Study of Etching Characteristics of the ZnO Thin Film Using a SF6/Ar Inductively Coupled Plasma)

  • 강성칠;이윤찬;이진수;권광호
    • 한국전기전자재료학회논문지
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    • 제24권12호
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    • pp.935-938
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    • 2011
  • The etching characteristics of ZnO and etch selectivities of ZnO to $SiO_2$ in $SF_6$/Ar plasma were investigated using Inductively-coupled-plasma (ICP). The maximum etch rates of ZnO were 6.5 nm/min at $SF_6$(50%)/Ar(50%), Source power (700 W), Bias power (250 W), Working pressure(8 mTorr). The etch rate of ZnO showed a non-monotonic behavior with increasing from 0% to 50% Ar fraction in $SF_6$/ Ar plasma. The plasma diagnostic were characterized using Optical Emission Spectroscopy (OES) analysis measurements.

알칼리 금속 - 비활성 기체 반데르발스 복합체에 대한 양자화학적 계산 (ab initio Calculations on Alkali Atom - Rare Gas Van Der Waals Clusters)

  • 이보순;이성열
    • 대한화학회지
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    • 제44권3호
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    • pp.190-193
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    • 2000
  • M-Rg 및 M-Rg2 (M=Li,Na,Rg=He,Ar) 반데르발스 복합체들에 대한양자화학적계산을 시행하였다. AIl-electron MP2(6-311++G(3df,3pd))에 의하여 계산된 LiHe, LiAr 및 NaAr의 균형 핵간 거리와 결합 에너지는 실험값과 잘 일치하였다. $LiHe_2,\;LiAr_2$$NaAr_2$에 대하여 계산된 분광학적 성질들도 또한 계산하였다.

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증강현실 패션플랫폼에 대한 경험적 가치가 플랫폼 선호도에 미치는 영향 (The Effect of Experiential Value of AR Fashion Platform on Platform Preference)

  • 이하경;허희진
    • 한국의류학회지
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    • 제46권6호
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    • pp.987-1003
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    • 2022
  • This study explores the effect of experiential value of AR fashion platform on platform preference. Based on the SOR theory, the effects of visual appeals, entertainment, service excellence, and efficiency on platform attitudes, mediated by intrinsic enjoyment and escapism, are tested. The participants respond to the questions after watching the video clip, using an AR fashion platform. A total of 252 data is analyzed using SPSS 26.0 for descriptive statistics and reliability analysis and AMOS 26.0 for confirmatory factor analysis and structural equation modeling. The results show visual appeals, entertainment, and efficiency influence platform preference, mediated by intrinsic enjoyment. Entertainment also influences platform preference, mediated by escapism. The moderating effect of the AR service pre-experience is also explored. For the group with the AR service experience, entertainment and efficiency has a positive effect on intrinsic enjoyment, leading to AR platform preference. For the group without an AR service experience, only entertainment influences the AR platform preference, mediated by intrinsic enjoyment; however, there are no factors which increase escapism. The findings of this study contribute to find the marketing directions for the AR service users, by offering appropriate experiential values based on their prior AR experience.

증강현실을 이용한 위치기반 SNS 시스템 구현 (Implementation of a Location-Based SNS System Using AR)

  • 김경섭;박영철;엄찬진;이윤복;이상호
    • 한국인터넷방송통신학회논문지
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    • 제19권6호
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    • pp.133-138
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    • 2019
  • 현대 사회에서 급부상한 분야의 대표적인 하나가 SNS이고, 최근 각광을 받고 있는 기술이 AR 기술이다. 본 논문에서는 SNS에 AR기술을 접목하여, 새로운 형태의 커뮤니티 기능을 제공하고 관련 기술을 개발하고자 한다. 본 논문에서 개발한 시스템은 현재 위치에서 AR 메시지 띄우기, AR을 이용한 길 찾기 등 위치정보와 AR을 응용한 커뮤니티 기능들을 제공하여 사용자들간의 차별화된 소통을 제공한다. 뿐만 아니라, 본 논문은 위치 정보 기반 증강현실 구현을 위해 필수적인 지도정보를 얻기 위한 방법으로 기존 지도 API의 특성을 고려하여 기존 지도 API 활용 방법을 제시한다.

Adenophorae Radix Attenuates Mast Cell-mediated Allergic Inflammation through Down-regulation of NF-κB/ Caspase-1 Activation

  • Myung, Noh-Yil
    • 한국자원식물학회지
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    • 제33권6호
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    • pp.659-665
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    • 2020
  • Adenophorae Radix (AR) has been used as a traditional medicine for various diseases. However, the regulatory mechanisms of AR in allergic inflammation are not yet understood. The present study was conducted to investigate the effect and mechanisms of AR on the mast cell-mediated allergic response. To determine the pharmacological mechanisms of AR in allergic inflammation, we evaluated the effects of AR on the production of tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-1β and IL-8 as well as the activation of nuclear factor-κB (NF-κB) and caspase-1 in phorbol 12-myristate 13-acetate plus calcium ionophore A23187 (PMACI)-stimulated human mast cells (HMC-1). Our results demonstrated that AR effectively attenuated the PMACI-induced production of TNF-α, IL-6, IL-1β and IL-8 in stimulated HMC-1. Additionally, we showed that the inhibitory effect of AR on inflammatory cytokines in PMACI-stimulated HMC-1 cells involved the suppression of the activation NF-kB/caspase-1 in PMACI-stimulated HMC-1. Collectively, these findings provide experimental evidence that AR may be a useful candidate for the treatment of allergic inflammation.