• 한방재활의학과학회지
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• 제18권2호
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• pp.81-96
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• 2008

Objectives : This study was performed to investigate inhibitory effects of Gamipalmul-tang($jiaweibawu-t{\bar{a}}ng$) on the hematological and histological changes of obese mice. Methods : C57BL/6 mice were divided into four groups (normal group, high fat diet with normal saline, high fat diet with reductil, high fat diet with Gamipalmul-tang($jiaweibawu-t{\bar{a}}ng$) and fed for 8 weeks. Body weight change, final increase of body weight, ALT, AST, creatinine, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, glucose, cell viability by cytotoxicity, the expression of ${\beta}3AR$ in 3T3-L1 cell, the expression of leptin, ${\beta}3AR$ and serotonin in adipocyte tissue and size of adipocyte were observed in 8 weeks. Results : 1. In 3T3-L1 cell. the expression of ${\beta}3AR$ was increased significantly. 2. The final increase of body weight in obese-mouse were decreased significantly. 3. The level of AST, ALT were decreased significantly. 4. The level of LDL-cholesterol was decreased significantly and HDL-cholesterol was increased significantly. 5. The levels of triglyceride was decreased and leptin and glucose were decreased significantly. 6. In adipocyte tissue, the expression of ${\beta}3AR$ were increased significantly. 7. In adipocyte tissue, the expression of leptin and serotonin were decreased significantly. 8. The size of Adipocyte was decreased. Conclusions : On the basis of these results, we concluded that Gamipalmul-tang($jiaweibawu-t{\bar{a}}ng$) has inhibitory effects in rat.

• 한국정보통신학회논문지
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• 제18권2호
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• pp.482-487
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• 2014

본 연구는 testosterone이 지방세포생성에 미치는 영향과 그것에 대한 분자생물학적 조절기전을 역전사-중합효소 연쇄반응과 일시적인 형질전환 분석을 통해 조사하였다. 정소절제수술 마우스(CAST)에 비해 testosterone이 처리된 정소절제수술 마우스(CAST+T)는 백색지방조직 무게와 지방세포 특이유전자($PPAR{\gamma}$와 aP2)의 발현이 감소되었다. In vivo 결과와 일치되게, testosterone 처리는 분화된 3T3-L1세포에서의 triglyceride축적과 지방세포 특이유전자($PPAR{\gamma}$와 aP2)의 발현을 억제시켰다. Testosterone에 의해 활성화된 androgen receptor(AR)는 $PPAR{\gamma}$ transfection에 의해 유도된 luciferase reporter gene 활성을 억제하였다. 따라서 본 연구결과는 testosterone이 AR을 통해 지방세포분화에 대한 $PPAR{\gamma}$의 작용을 억제 조절한다는 것을 시사하고 있다.

• 한국물환경학회지
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• 제34권6호
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• pp.642-649
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• 2018

The effect of gas sparging on sonochemical oxidation was investigated in a 300 kHz sonoreactor under various liquid height/volume conditions ($5{\sim}30{\lambda}$, 3.4 ~ 9.0 L), determined by the wavelength of the applied frequency. The electrical input power was maintained constant for all cases . Sonochemical activity drastically decreased from $15{\lambda}$ and the liquid height of $10{\lambda}$ was suggested as the optimal height for 300 kHz without gas sparging. In our previous research, the sonochemical activity observed was five-times higher when air sparging was applied for 36 kHz. On the other hand, no enhancement was obtained at 10, 15, 25 and $30{\lambda}$ using air sparging (1, 3, and 6 L/min) for 300 kHz in this study $20{\lambda}$ and optimization of gas sparging was conducted at $20{\lambda}$ using various gases including air, Ar, $O_2$, $N_2$, and mixtures of Ar and $O_2$. It was found that gas sparging using pure Ar or pure $O_2$ resulted in lower sonochemical activity compared to that of air sparging due to the imbalance between the intensity of cavitation phenomena and the generation of oxidizing radical species. Consequently, the gas mixture of $Ar:O_2$ = 80 % : 20 % (DO saturation ${\approx}100%$) was suggested as an optimal gas sparging condition.

• Communications for Statistical Applications and Methods
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• 제12권1호
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• pp.169-179
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• 2005

In this study, we investigate the effects of the weight function in the bounded influence regression quantile (BIRQ) estimator for the AR(l) model with additive outliers. In order to down-weight the outliers of X -axis, the Mallows' (1973) weight function has been commonly used in the BIRQ estimator. However, in our Monte Carlo study, the BIRQ estimator using the Tukey's bisquare weight function shows less MSE and bias than that of using the Mallows' weight function or Huber's weight function. Thus, the use of the Tukey's weight function is recommended in the BIRQ estimator for our model.

• 한국결정성장학회지
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• 제28권2호
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• pp.63-68
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• 2018

Natural convection of a two dimensional laminar steady-state incompressible fluid flow in a rectangular enclosure has been investigated numerically for low aspect ratios with the physical vapor transport crystal growth. Results show that for aspect ratio (Ar = L/H) range of $0.1{\leq}Ar{\leq}1.5$, with the increase in Grashof number by one order of magnitude, the total mass flux is much augmented, and is exponentially decayed with the aspect ratio. Velocity and temperature profiles are presented at the mid-width of the rectangular enclosure. It is found that the effect of Grashof number on mass transfer is less significant when the enclosure is shallow (Ar = 0.1) and the influence of aspect ratio is stranger when the enclosure is tall and the Grashof number is high. Therefore, the convective phenomena are greatly affected by the variation of aspect ratios.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2003년도 하계종합학술대회 논문집 Ⅳ
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• pp.2383-2386
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• 2003

요즘 어린이 교재들은 예전에 비한다면 급속도의 발전을 이루고 있어서, 앞으로도 다양한 컨셉과 아이디어로 계속 발전될 경향이다. 하지만 현재까지의 보통 낱말카드나 그래픽들은 2D로 이루어져 있어서 현실감이 떨어지는 교육이 되는 경우가 많다. 그렇다고 현실감을 주기 위해 어린이들이 갖고 놀도록 커다란 3D 의 장난감들을 갖게 된다면 이들이 차지하는 공간은 너무나 많아진다. 사실 아이들이 있는 가정들을 보면 공간의 부족 때문에 갖고 있던 교재나 장난감들을 버리기도 하는 것이 요즘 현실이기 때문이다. 본 논문은 이런 문제점들을 보완하기 위해 AR(Augmented Reality)Toolkit[l]을 응용한 어린이 교재를 제안한다 공간절약형으로 정육면체 패턴을 만들어 공간절약도 되고, 이 패턴(pattern) 위에서 3 차원 영상도 보고 패턴을 교체해 가면서 다양한 재미도 느낄 수 있는 교재를 구현해 보고자 한다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 추계학술대회 논문집 전기물성,응용부문
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• pp.21-23
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• 2005

The electron transport coefficients, the electron drift velocity W, the longitudinal diffusion coefficient $ND_L$ in $C_{3}F_{8}-Ar$ mixture gases were measured by Double shutter drift tube and calculated by multi-term approximation of the Boltzmann equation over the wide E/N range from 0.03 to 100 Td. And an inelastic collision cross sections for $C_{3}F_{8}$ molecular gas were redetermined for quantitative characteristic analysis.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제42회 동계 정기 학술대회 초록집
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• pp.514-514
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• 2012

면방전 구조의 대가압 DBD플라즈마 소스를 제작하여 Ar과 N2 기체를 유입하여 미생물인 Fungi의 변화를 관찰하였다. 면방전 구조의 DBD플라즈마 소스는 유리기판위에 포토리소그라피 공정으로 미소전극을 형성하여 고밀도의 방전셀을 형성하였다. 방전시 발생하는 열에 의한 효과의 제어를 위하여 냉각장치를 장착하였다. 또한 유리기판과 포토리소그라피 공정은 방전영역에 제한없이 다양한 크기의 소스제작이 가능하다. 셀 피치가 $400{\mu}m$이며 $cm^2$ 당 200여개의 방전 셀로 구성되어 있어서 기존 메쉬타입의 DBD플라즈마 장치에 비해 균일하게 플라즈마를 조사할 수 있으며 플라즈마 제트 장치에 비해서는 넓은 면적을 동시에 조사할 수 있게 되었다. Ar 과 N2기체를 3 L/min의 유량으로 방전공간에 유입하면서 1 kV의 구동전압으로 플라즈마를 발생하였다. 이 경우 플라즈마의 조사시간을 20 s, 40 s, 60 s 간격으로 변화를 주며 Fungi의 변화를 관찰하였다.

• Mass Spectrometry Letters
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• 제10권1호
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• pp.27-31
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• 2019

In this article, the properties of ${CO_2}^+(CO_2)_n$ clusters in a Paul ion trap have been investigated using mass-selective instability mode which conducted by chosen precursor ions, mainly $Ar^+$ and ${CO_2}^+$ produced by a mixture of Ar and $CO_2$. Exposure of ${CO_2}^+$ ions to $CO_2$ molecules, lead to the formation of ${CO_2}^+(CO_2)_n$ clusters. Here, Ar gas react as a buffer gas and lead to form ${CO_2}^+(CO_2)_n$ cluster by collisional effect.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2017년도 추계학술논문요약집
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• pp.331-332
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• 2017