• Proceedings of the Korean Biophysical Society Conference
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• 2003.06a
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• pp.47-47
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• 2003

The presenilin 1 (PS1) or PS2 is an essential component of the ${\gamma}$-secretase complex, which mediates the intramembrane proteolysis of selected type-I membrane, including the ${\beta}$-amyloid precursor protein (APP) to yield A${\beta}$. Familial Alzheimer's disease (FAD)-associated mutations in presenilins give rise to an increased production of a highly amyloidogenic A${\beta}$42. In addition to their well-documented proteolytic function, the presenilins play a role in calcium signaling. We have previously reported that presenilin FAD mutations cause highly consistent alterations in intracellular calcium signaling pathways, which include deficits in capacitative calcium entry (CCE), the refilling mechanism for depleted internal calcium stores. However, molecular basis for the presenilin-mediated modulation of CCE remains to be elucidated. In the present study, whole-cell patch clamp method was used to identify a specific calcium-permeable ion channel current(s) that is responsible for the CCE deficits associated with FAD-linked PS1 mutants. Unexpectedly, both voltage-activated and conventional store depletion-activated calcium currents I(CRAC), were absent in HEK293 cells, which were stably transfected either with wild-type or FAD mutant (L286V, M146L, and delta E9) forms of PS1. Recently, magnesium-nucleotide-regulated metal cation current, or I(MagNum), has been described and appears to share many common properties with I(CRAC) including calcium permeability and inhibitor sensitivity (e.g. 2-APB). We have detected I(MagNum) in all 293 cells tested. Interestingly, FAD mutant 293 cells developed only about half of currents compared to PS1 wild type cells.

• Journal of Digital Convergence
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• v.15 no.3
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• pp.301-306
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• 2017

With the popularization of smart-phone, a variety of application service user is a rising trend now. In contrast, studies concerning library application service that cast a long shadow over the life of students and citizens still lacking in many ways. This study evaluates user experience of Young-in Si public library application service, and investigates user requirements. I searched the real user reviews about Young-in Si library application both App store and Android market. As the final outcome, I found inconveniences and improvements of this service. The application is intuitive, but requires consistent design, strong identity and customizing main page. It will be suggested specific guidelines for the public library mobile services in other areas.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.10
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• pp.1361-1370
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• 2018

With the advent of OTT, the new concept of content delivery service is growing interest in the market, the development of appropriate equipment and application program is needed. In order to provide OTT service, a system to receive UHD broadcast to collect free content is needed. In this study, we designed an OTT service providing system that operates on 4K UHD video adapter hardware capable of IPTV service. First, we analyzed the situation to provide video free contents service and implemented a system to collect free contents. To validate the research and to make practical use of it, we have developed a mobile program for free content service and distributed it through the Google App Store. It is also installed in an OTT box with the ability to provide free content on the open market and is in service in several countries including Brazil.

• International journal of advanced smart convergence
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• v.8 no.2
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• pp.18-29
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• 2019

In the field of Human-Computer Interaction design, persuasive design has gradually been applied to the system development and design process, especially for mobile application design. However, most mobile applications have hitherto a very short using lifecycle. Especially, design features with long-term persuasive effectiveness remain to be further researched and developed. In this study, we focused on investigating and identifying the durative persuasive design characteristics through a data mining process and evaluating the durative effectiveness through a long-term observation process. Total five hundred healthcare-related mobile applications were selected from Apple iTunes Store and a mixed method was conducted to extract the most common persuasive design characteristics. Based on the results of extraction, a representative healthcare-related mobile application was selected as experimental subject. Total one hundred and twenty participants were observed during a six-months experiment and the monitoring data of app usage of all participants was collected once a week. According to the evaluation model for behavior change identification process, participants with habit formation features were proved to have a significant long-term perception level for ten persuasive design characteristics. Further interview research was performed to investigate the participant's long-term perceptions on those characteristics for the purpose of identifying the durative persuasions. The results indicated that a long-term durative effectiveness can be observed and healthcare-related apps designed with those characteristics could have durative effectiveness. This study may contribute to the improvement of future mobile application designs in user experience and durative persuasion, as well as bringing future benefits for both mobile application developers and users.

• Journal of Advanced Navigation Technology
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• v.23 no.1
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• pp.55-60
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• 2019

The web is one of the most intimate technologies in people's daily lives, and most of the time, people are sharing data on the web. Simple messenger, news, video, as well as various data are now spreading through the web. In addition, with the emergence of Web assembly technology, the programs that run in the existing native environment start to enter the domain of the Web, and the data shared by the Web is now getting wider and larger in terms of VR / AR contents and big data. Therefore, in this paper, we have studied how to effectively deliver web contentsto users who use Web service by using service worker that can operate independently without being dependent on browser and cache API that can effectively store data in web browser.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.26 no.6
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• pp.907-913
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• 2022

Approximately 70% of smartphone users around the world use Android operating system-based smartphones, and malicious apps targeting these Android platforms are constantly increasing. Google has provided "Google Play Protect" to respond to the increasing number of Android targeted malware, preventing malicious apps from being installed on smartphones, but many malicious apps are still normal. It threatens the smartphones of ordinary users registered in the Google Play store by disguising themselves as apps. However, most people rely on antivirus programs to detect malicious apps because the average user needs a great deal of expertise to check for malicious apps. Therefore, in this paper, we propose a method to classify unnecessary malicious permissions of apps by using only the categories and permissions that can be easily confirmed by the app, and to easily detect malicious apps through the classified permissions. The proposed method is compared and analyzed from the viewpoint of undiscovered rate and false positives with the "commercial malicious application detection program", and the performance level is presented.

• Journal of Internet of Things and Convergence
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• v.9 no.1
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• pp.57-64
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• 2023

In this paper, we propose a smart umbrella stand based on the Internet of Things (IoT) that helps people to pack their umbrellas more easily. The proposed smart umbrella stand offers three functions. First, it receives weather information, and a hidden umbrella handle will automatically become visible when it rains, making it easier to grab. Second, the smart umbrella stand is equipped with a heated air system, allowing it to effectively dry umbrellas that have become wet due to rain. This makes it more convenient for users to dry and store their rain-soaked umbrellas. Third, the smart umbrella stand enables users to monitor its current status, track weather conditions, and monitor the water level in the rain gutter through a dedicated application. The proposed smart umbrella stand aims to bring convenience to daily life by making it more convenient to carry an umbrella on rainy days or days with a high probability of rain.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.24 no.3
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• pp.139-145
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• 2024

Since COVID-19, most of people's main living spaces have been moved indoors. Due to this influence, many people's interest in companion plants continues to rise. People who raise companion plants often raise them for the purpose of emotional stability or air purification. In fact, plants have the effect of giving people a sense of emotional stability and the ability to purify indoor air is excellent depending on what kind of plant they are. However, if you do not have knowledge of plants, you will not know which plants have excellent air purification effects, and even if you grow them, you will face a problem that withers quickly. Therefore, in this paper, we develop an app that provides users who do not have prior knowledge to store and manage their MBTI and member information in a database using databases and MBTI, and based on this, recommend plant data that fits their preferences with the user and manage their schedules through calendars.

• Journal of Digital Contents Society
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• v.11 no.3
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• pp.315-322
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• 2010

This study focused on mobile trend in diffusion of smart phone. Presently, it has been evolved from digital nomad to smart nomad. Smart nomad era is based on digital technology with mobility and being smart. Smart nomad that is made up high-end device and intellectual content has changed structure of industry and life style. Smart phone is a core key in smart nomad era. In 2010 smart phone has been distributed about 2.5 hundreds million which is 20% of whole mobile phone sales and the volume of smart phone sales will be getting bigger and bigger in near future. Although, there are various reasons for success of smart phone market, this research focused 4 reasons: first, development of mobile device, second, evolution of mobile content distribution, third, support of government system, fourth, success of Docomo i-mode and Apple i phone. Smart phone will grow up more rapidly. Smart phone eco-system will be more competitive in the world. In Korea, smart phone eco-system also will be very competitive. For success in the middle of this competitive environment, Korea should lead the competitive phase with development of ability of creation software and content, construction of various partnership and evolution of next generation technology and service.

• Journal of Society of Preventive Korean Medicine
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• v.19 no.2
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• pp.103-112
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• 2015

Objective : To evaluate the status of mobile personal health records (mPHR) applications of Atopic Dermatitis, assessing general characteristics, information content, features of PHR content and functions. Method : Searches were conducted from Android's Google Play and iOS's App Store. Main criteria used to include mPHRs were: providing health information of PHR function of Atopic Dermatitis; operating in Korean or English; for human. Selected mPHRs were analyzed considering general characteristics, information contents, data elements, and application features. Results : 19 applications were included in this study. 15 were providing health information. Data elements of information included general information, symptom, diagnosis, treatment, prevention, management and FAQ. No single application contained all seven data elements. Only Eight applications had PHR function. In the features analysis, one PHR applications contained all eight PHR functional features; saving profile function, profiles supported, password, import data, export data, information provided, progress chart and push-up alarm. Conclusion : mPHR is an emerging health care technology. The majority of existing mPHR applications only provide one-way information. Application designed to help users and doctors to exchange mutual information was the only one. Also, there was no application that can record the Traditional Korean Medicinal treatment information. However, as the mobile market continues to expand it is likely that more comprehensive mPHRs will be developed in the near future. New advancements in mobile technology can be utilized to enhance Tranditional Korean Medical health care.