• Korean Journal of Pharmacognosy
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• v.40 no.3
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• pp.173-177
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• 2009

The in vitro antibacterial activities of honeybee(Apis mellifera. L) venom collected by a bee venom collector were investigated against several bacteria including antibiotic-susceptible and resistant Propionibacterium acnes. Honeybee venom was prepared with different concentrations and they showed strong antibacterial activites. Honeybee venom inhibited the growth of the tested antibiotic-resistant P. acnes at the concentration of 1 mg/ml. The inhibitory activities of the honeybee venom showed time-dependent manner. Honeybee venom did not influence the viability of human dermal fibroblast at the high concentration of less than 10 mg/ml. From these results, we expect that honeybee venom has strong antibacterial activities and has advantage for treating cure.

• International Journal of Contents
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• v.8 no.1
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• pp.55-60
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• 2012

Most Korean and overseas major portal sites include map servers to provide map services, and offer open APIs to allow their users to make use of maps or spatial information directly. At the early design stage, geographic spatial data do not tend to require high accuracy, and thus there would be no problem using data which have been obtained and then utilized through map servers provided by portal sites. This study has chosen the shortest route between starting point and destination, using GIS techniques. Moreover, for the chosen route, it also has calculated the elevation for the cross-section, using Google map and GPS measurements. This study aims to create APIs, which can extract vertical profile of routes from the Google Map server, by using JAVA, and to compare centerline profile results obtained by GPS(Global Positioning System) to explore their utilize abilities. The result demonstrated a height error of 0.5 to 1 m, compared to the GPS results, but they were mutually satisfactory. In short, the data extracted in this study are useful for centerline profile drawings in selecting routes, such as streets, Olle roads, and bike lanes.

• Current Research on Agriculture and Life Sciences
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• v.32 no.2
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• pp.63-66
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• 2014

The effects of a newly developed flower thinning formulation (FTF) on the vitality of the honey bee Apis mellifera were examined by measuring the activities of various digestive enzymes in adult worker bees. First, direct spraying of the FTF solution did not cause any behavioral changes or lethal effects for the honey bees based on 24 h observation. Second, oral ingestion of a sugar solution containing the FTF did not produce any significant change in the activities of amylase, proteinases, lipase, or acetylcholine esterase (AChE) in the worker bees 6 h or 24 h after treatment. Meanwhile, a commercial formulation containing sulfur compounds showed slightly reduced activities for several digestive enzymes and AChE, although no behavioral disturbance. Thus, the results of the present study suggest that the FTF is not toxic for honey bees, in terms of contact and ingestion. Therefore, this newly developed FTF can be used for flower thinning without any detrimental effects on pollinating insects.

• Food Science of Animal Resources
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• v.37 no.4
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• pp.599-605
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• 2017

Korean native honey (KNH) is much more expensive than European honey (EH) in Korea, because KNH is a favored honey which is produced less than EH. Food fraud of KNH has drawn attention of the government office concerned, which is in need of a method to differentiate between KNH and EH which are produced by the Asiatic honeybee, Apis cerana and the European honeybee, Apis mellifera, respectively. A method to discriminate KNH and EH was established by using duplex polymerase chain reaction (PCR) in this study. Immunochromatographic assay (IC) was examined to analyze the duplex PCR product. The DNA sequences of primers for the duplex PCR were determined by comparing cytochrome C oxidase genes of the two honey bee species. Chelex resin method was more efficient in extracting genomic DNA from honey than the other two procedures of commercial kits. The duplex PCR amplifying DNA of 133 bp were more sensitive than that amplifying DNA of 206 bp in detecting EH in the honey mixture of KNH and EH. Agarose gel electrophoresis and IC detected the DNA of 133 bp at the ratios of down to 1% and 5% EH in the honey mixture, respectively and also revealed that several KNH products distributed by internet shopping sites were actually EH. In conclusion, the duplex PCR with subsequent IC could also discriminate between KNH and EH and save time and labor.

• Korean Journal of Veterinary Service
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• v.34 no.1
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• pp.87-93
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• 2011

This study was conducted to investigate effects of honeybee venom (Apis mellifera L. BV) on the calving, the growth performance and blood chemistry occurrence of Hanwoo calves. A total of twenty, a 3 day old male experimental calves were allocated into four groups, BV treated (0.05 mg/kg, 0.1 mg/kg and 0.2 mg/kg BV, n=5, respectively) and non-treated (n=5, Control) of Hanwoo calves in Icheon, Kyonggi province. Treatment of BV in calves increased body weight and weight gain during 60 days compared with control group. The concentrations of IgG in blood were significantly increased in BV groups compared with control at 60 days after treatment with BV. Cholesterol and glucose concentrations in BV group were significantly lower with control at 60 days. There were no differences in plasma biochemical components including aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphate (AKLP), total protein, albumin, globuline, total bilirubin, creatinine, blood urea nitrogen (BUN) and $Ca^+$. In conclusion, the BV treatment had effect on growth, the score of the calf scours and blood biochemical profile.

• The Korean Journal of Food And Nutrition
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• v.31 no.1
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• pp.89-93
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• 2018

In this study, we investigated the nutritional composition including proximate, amino acid, vitamin, minerals, and the antioxidant activity of green tea (Camellia sinensis) pollen grains collected by Apis mellifera bees, for use as a health food. The crude protein and fat content was estimated at 26.14% and 3.49%, respectively. Eighteen amino acids were identified in green tea pollen, including 8 essential amino acids and 10 non-essential amino acids. The predominant amino acids were glutamic acid, proline and aspartic acid accounting for about 33.3% of total free amino acids. The concentration of vitamin C was the highest value of 35.7%, followed by $B_3$ and $B_2$ among the detected vitamins. The predominant minerals were potassium (790.32 mg/100g), followed by phosphorus (707.52 mg/100g) and sulfur (302.67 mg/100g), whereas copper, zinc and sodium were detected as minor elements. The antioxidant activity and phenolic content accounted for 33.8% at $500{\mu}g/mL$ extract and $2.55 {\mu}g/mg$, respectively.

• Journal of the Korea Society of Computer and Information
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• v.22 no.10
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• pp.47-54
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• 2017

In this paper, we propose a connected car platform architecture called Mobile Second for developing of verity convergence services. A Mobile Second platform architecture is designed to provide more powerful and diverse convergence services for vehicles and drivers by applying technologies of Connected Car and ICT Convergence in various ways. The Mobile Second platform is implemented by applying Tizen IVI and Android to hardware platforms for IVI, Nexcom's VTC1010 and Freescale's i.MX6q/dl respectively. The Mobile Second platform provides the driver with the vehicle's information via IVI devices, mobile devices and PCs, etc., and provides Vehicle Selective Gateway(VSG) and Vehicle Control Framework for the driver to control his/her vehicle, and also provides a web framework to enable the use of VSG's APIs for the monitoring and controlling the vehicle information in various mobile environments as well as IVI devices. Since the Mobile Second platform aims to create new variety of services for Connected Car, it includes service frameworks for Smart Care / Self diagonostics, Mood & Entertainment services, and Runtime, libraries and APIs needed for the development of related applications. The libraries given by the Mobile Second Platform provides both a native library for native application support and a Java Script-based library for web application support, minimizing the dependency on the platform and contributing the convenience of developers at the same time.

• YAKHAK HOEJI
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• v.60 no.2
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• pp.53-57
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• 2016

This study was performed to examine the skin phototoxicity of purified bee venom (Apis mellifera L.) collected using bee venom collector. To confirm whether the gel containing purified bee venom (BV gel) causes photototoxicity when used for the skin medicinal products, phototoxicity testing was conducted using guinea pig models. The BV gel (0.1 ml/site) was administered transdermally to guinea pigs. 8-MOP was used to introduce positive control response. After administration, the guinea pigs were irradiated with UVA ($15J/cm^2$) with doses based on standard phototoxicity study guidelines. In the weight measurement and clinical observation, BV gel groups didn't show any significant changes compared with control group. BV gel groups did not show any symptoms such as erythema and edema formation of skin. This study demonstrated that BV gel has promising potential external treatment for topical uses that do not induce significant levels of skin phototoxicity.

• Proceedings of the KIEE Conference
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• 1998.07c
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• pp.1121-1124
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• 1998

Inchon International Airport(IIA) is constructed for Northeast Asia Gate as is important for IIA to become a 21 century's leader in the world, as is planned for open at december 2000 as a important economic link for unified korea. Airport Power Information System(APIS) is designed through investigation of advanced domestic and international example. In addition to power facility operation it is designed for using an information infrastructure of whole airport. APIS is newly designed for uninterupted power supply, effective power management, information infrastructure's construction. making a profit by positively introduction of new technology for collection and conservation of power related data, correlation with airport infra systems, data interrelative arrangement about related systems like outdoor lighting system and automatic measuring record, CCTV systems for remote power facility monitoring, and promotion of management ability in the emergency status.

• Korean Journal of Computational Design and Engineering
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• v.11 no.6
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• pp.412-421
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• 2006

Recently, the needs for sharing and exchanging drawing information between 2D and 3D data in complex facilities are well recognized throughout the construction industries. The purpose of this study is to propose an information framework to represent 3D IFC (Industry Foundation Classes) -based drawing of building services in complex facilities as 2D drawing. In this study, 1) attributes of building service objects which are used in 3D CAD system are analyzed and present drawing standards are analyzed, 2) based on the analysis, an information framework is developed to represent 3D model in 2D representation, and 3) further more, to test a compatibility of the information sharing framework, number of standardized APIs and an IFC2Dbrowser are developed during the study.