• 대한한방내과학회지
• /
• 제32권2호
• /
• pp.243-258
• /
• 2011

Objectives : This study investigated the hypolipidemic and antioxidant effects of Curcuma radix using a rat model induced by poloxamer 407 injection. Methods : Serum lipid parameters and oxidative stress-associated biomarkers were determined. Additionally, hepatic cholesterol and triglyceride as well as lipid metabolism-associated gene expressions were observed in hepatic tissue. Results : 1. Curcuma radix ameliorated elevation of serum cholesterol, triglyceride, LDL-cholesterol, MDA, hepatic cholesterol level, and reduction of serum TAC, SOD, GSH, GSH-reductase level. 2. Curcuma radix augmented up-regulated ACAT gene expression. 3. Curcuma radix almost completely ameliorated down-regulated CYP-7A1 but up-regulated HMG-CoA gene expression. Conclusions : The hypolipidemic and antioxidant properties of Curcuma radix were evidenced. This study provides a scientific basis for the clinical application of Curcuma radix and development of hypolipidemics using this herb in the future.

• Transactions on Electrical and Electronic Materials
• /
• 제15권2호
• /
• pp.81-86
• /
• 2014

The process parameter in optimized KOH alkali activation of soft carbon series coke material in high purity was set with DOE experiments design. The activated carbon was produced by performing the activation process based on the set process parameters. The specific surface area was measured and pore size was analyzed by $N_2$ absorption method for the produced activated carbon. The surface functional group was analyzed by Boehm method and metal impurities were analyzed by XRF method. The specific surface area was increased over 2,000 $m^2/g$ as the mixing ratio of activation agent increased. The micro pores in $5{\sim}15{\AA}$ and surface functional group under 0.4 meq/g were obtained. The contents of the metal impurity in activated carbon which is the factor for reducing the electrochemical characteristics was reduced less than 100 ppm through the cleansing process optimization. The electrochemical characteristics of activated carbon in 38.5 F/g and 26.6 F/cc were checked through the impedance measuring with cyclic voltammetry scan rate in 50~300 mV/s and frequency in 10 mHz ~100 kHz. The activated carbon was made in the optimized activation process conditions of activation time in 40 minutes, mixing ratio of activation agent in 4.5 : 1.0 and heat treatment temperature over $650^{\circ}C$.

• Journal of Pharmaceutical Investigation
• /
• 제29권1호
• /
• pp.47-53
• /
• 1999

Gastrodia elata (GE) is an oriental medicinal herb which has been used traditionally for the treatment of various brain diseases including convulsion and epilepsy. The purpose of this study was to determine pharmacokinetic parameters of 4-hydroxy-3-methoxybenzaldehyde (HMBA) and p-hydroxybenzaldehyde (PHBA), constituents of GE, in rats. Male rats were cannulated in the femoral vein, femoral artery, bile duct and ureter. They received a single i.v. bolus dose of either HMBA or PHBA through the femoral vein. The concentration of HMBA or PHBA in plasma, bile and urine samples were analyzed by reversed-phase HPLC. HMBA and PHBA have very short half-lives, i.e. 4.03 and 2.26 minutes respectively. Most of HMBA and PHBA were thought to be eliminated through metabolism as the metabolized fraction approaches unity. Derivatives of HMBA or PHBA with longer biological half-lives should be designed to develop better anticonvulsants and more complete qualitative and quantitative understanding of the overall pharmacokinetic fate of these compounds awaits further investigation.

• Design & Manufacturing
• /
• 제11권1호
• /
• pp.30-33
• /
• 2017

In this study, the mold technology for manufacturing of porous implant was investigated. Firstly, we considered the concept of insert molding technology with 3D printing of porous inert part. The part on implant was designed in the end region of the implant. And then main implant bodies were manufactured using conventional machining method. The other porous parts were designed and optimized with molding simulation. As the feature size of porous implant was so small that perfect feature of it using 3D printing technology could not be obtained. So, we proposed another scheme for manufacturing of the porous implant in the replace of the former approach. Polymer mold cores with 3D printing technology were considered. The effects of addictive manufacturing process parameters on the properties of mechanical and dimensional accuracy were investigated. Direct 3D printed polymer mold cores were designed and manufactured under the simulation of thermal and molding analysis. It was shown that 3D printed mold core with polymer could be adapted to the injection molding for porous implant.

• 한국항공우주학회지
• /
• 제33권12호
• /
• pp.39-47
• /
• 2005

본 연구에서는 고속 충격환경을 경험하는 플라스틱 구조 소재에 대한 인장속도별 물성 평가 시험 및 구조건전성 평가에 음향방출 기법을 적용하였다. 인장속도별 물성 평가시험을 통하여 플라스틱 소재 구조물의 건전성 평가에 유용한 음향방출 신호 특성 인자들을 획득하였다. 인장속도에 따른 인장강도는 저속 인장속도 구간에서는 속도가 증가함에 따라 강도가 증가하는 특성을 보여주었으나 일정 속도 영역 이상의 고속 인장시험에서는 인장속도 증가와 무관하게 일정한 강도 값을 나타내었다. 정적 압축 구조시험에서는 음향방출 기법을 적용함으로써 플라스틱 쉘 구조물의 균열발생 시점 및 위치 등을 정확히 평가할 수 있었다.

• 대한원격탐사학회:학술대회논문집
• /
• 대한원격탐사학회 2006년도 Proceedings of ISRS 2006 PORSEC Volume II
• /
• pp.602-605
• /
• 2006

This study is to apply QuickBird satellite image for the simulation of storm runoff in a small rural watershed. For a 1.05 $km^2$ watershed located in Goesan-Gun of Chungbuk Province, the land use from the QuickBird image was produced by on-screening digitising after ortho-rectifying using 2 m DEM. For 3 cases of land use, soil and elevation scale (1:5,000, 1:25,000 and 1:50,000), SCS (Soil Conservation Service)-CN (Curve Number) and the watershed physical parameters were prepared for the storm runoff model, HEC-HMS (Hydrological Modelling System). The model was evaluated for each case and compared the simulated results with couple of selected storm events.

• 대한원격탐사학회:학술대회논문집
• /
• 대한원격탐사학회 2007년도 춘계학술대회 논문집
• /
• pp.76-81
• /
• 2007

융설 모형의 중요 매개변수인 적설분포면적은 실제 우리나라에서 적설과 관련한 관측 자료의 부족으로 인해 매개변수 추정이 어렵다. 이러한 문제점 해결을 위해 원격탐사기법을 활용하여 적설분포면적을 추출하였다. 본 연구에서는 1997년 부터 2006년 까지의 겨울철 NOAA (National Oceanic and Atmospheric Administration)의 AVHRR(Advanced Very High Resolution Radiometer) 위성영상의 8 sets의 총 108개 영상을 이용하여 적설분포면적을 추출하였고，기상청의 지상기상관측소의 최섬적설심 자료를 이용하여 GIS 자료를 구축함으로써 적설심의 공간적 분포를 추출하였다. 이를 국내 5대유역인 한강，낙동강，금강，영산강，섬진강 유역에 대하여 융설모형의 주요 매개변수인 적설분포면적，유역 평균， 최대 적설심과 적설분포감소비곡선을 구축하였다. 그 중 적설분포면적감소곡선 (SDC : Snow cover Depletion Curve)는 적설분포면적의 감소형태를 나타내 주는 지표로써 융설의 가장 민감한 매개변수이다. 이를 국내 5대 강 유역에 대해 구축하여 정량화 하였다.

• 대한영양사협회학술지
• /
• 제6권2호
• /
• pp.171-178
• /
• 2000

The purpose of this study was to obtain basic data of nutrition education for obese children in Seoul and to examine dietary habits, dietary behaviors, and body image recognition before and after nutrition education. A convenience sample of 69(male : 54, female : 15) obese children was selected from "98 Children Nutrition Camp" in Seoul. The survey design employed a structured questionnaires. The results of this study were summarized as follows ; 1. Anthropometric parameters such as height, weight were measured in 69 obese subjects of age 10~12. 2. Effects of nutrition knowledge were gained by dietary habits, dietary behaviors and body image recognition. 3. Comparison of nutrition knowledge scores for obese children was to obtain basic data of effects for nutrition education.

• 한국인터넷방송통신학회논문지
• /
• 제9권6호
• /
• pp.43-48
• /
• 2009

무선 메쉬 네트워크(Wireless mesh networks, WMNs)는 Ad-hoc 네트워크와는 달리 백본망 구조를 가지고 있기 때문에 이동성이 적고, 단말들이나 다른 망들과 다중경로로 통신이 가능하다. 무선 메쉬 네트워크에서는 기존의 ad-hoc 네트워크의 알고리즘을 보완한 ETX, ETT, MIC 등과 같은 라우팅 경로선정 메트릭이 제안되고 있다. 제안된 다양한 라우팅 메트릭에는 최소의 흡수를 고려하는 Hop_count, 링크 품질을 고려하는 ETX(Expected Transmission Count)나 ETT(Expected Transmission Time)와 같은 metric이 존재한다. 하지만 ETX의 경우 전송률을 구할 때 각 방향에서 측정패킷의 조건이 달라 실질적인 전송률을 제공해주지 못한다는 단점이 있다. 본 논문에서는 ETX를 개선하여 hop_count를 반영하고, 실질 전송률을 고려하는 IETC(Improved Expected Transmission with hop count)를 제안하였다. 실험을 통해 제안된 메트릭이 전송율과 경로 선정에 있어서 기존 메트릭보다 나은 결과를 보였다.

• 한국환경과학회지
• /
• 제15권5호
• /
• pp.431-438
• /
• 2006

The strength, water permeability, and photo-degradation efficiency of NOx of porous concrete with a new concept were studied in this paper. The porous concrete was comprised of coarse aggregate of maximum size 40 mm, cement, silica fume, water and air-entraining(AE) water reducing agent. The strength of porous concrete was strongly related to its matrix proportion and compaction energy. An experimental test was carried out to study the parameters of cement proportions and silica fume content for pavement applications of porous concrete which were paving a footpath, a bikeway, a parking lot, and a driveway. The regressed equations of relation-ships between compressive strength and flexural strength, and coefficient permeability and void ratios were indicated as y=7.69x+71.74 and $y=0.42e^{0.28x}$. A method of making an air purification-functioning road, which was spraying a mixture of a photocatalyst, cement, and water onto the surface of the road, was suggested.