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A review on Phytochemistry and pharmacological Activities of Cirsium setidens (Dunn) Nakai (고려엉겅퀴(Cirsium setidens (Dunn) Nakai)의 구성성분 및생리활성에 관한 리뷰)

  • MiAe Cho;Bumjung Kim
    • The Korea Journal of Herbology
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    • v.38 no.4
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    • pp.31-43
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    • 2023
  • Objectives : The objective of this study was to investigate the phytochemistry and pharmacological activities of Cirsium setidens. Methods : Domestic and international articles about Cirsium setidens were investigated. A review was perfoemed via DB searching engine such as Sci.Direct, Springer, DBpia, KISS, Google scholar, Kipris, and so on. Total 73 listed literature were classified by compound analysis and pharmacological efficacy. Results : C. setidens contains pectolinarin and its glycoside, pectolinarigenin as index compounds, and linarin, apigenin, diosmetin, scopoletin, acacetin, cirsimarin, cirsimaritin, setidenosides A and B, silymarin, hispidulin, 92 volatile compounds, and 15 fatty acids. The Pharmacological activities of C. setidens has been reported to inhibit of platelet aggregation and fat accumulation in the liver, inhibit to hepatitis, anti-cancer, antibacterial, skin improvement, hair growth, liver protection, anti-diabetic, anti-inflammatory, sedative. Also, It has been reported the effect of cholesterol-lowering and anti-obesity, neuroprotective effects, increasing human stem cell viability, inhibiting osteoclast formation and osteogenic differentiation. Conclusion : This reviews showed that C. setidens which has been traditionally used for the treatment of inflammation and hypertension, has anticancer and river protective effect, as well as hair loss and diet. In order to maximize the efficacy of C. setidens, research has also begun on the effect of processing processes such as fermentation or fine powdering and combining natural plant resources.

An Analysis of the Class 'Philosophy' in the 5th Edition of Korean Decimal Classification and Relative Index (KDC 제5판 철학류 항목 전개에 관한 소고)

  • Kang, Soon-Ae;Kim, Hyung-Sook
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.20 no.3
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    • pp.65-80
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    • 2009
  • This research analyzes the revised philosophy class in the 5th Edition of Korean Decimal Classification. It depends on the 1st Edition of KDC despite of the fact that contents and words were revised and changed, numbers for classification were moved, and indices were removed from the previous Edition of KDC. The object of the 5th Edition of KDC, metaphysics and eistemology are organized in the same sub-class(綱) through modifying, sex psychology, development psychology, physiognomy fortune judgment, applied psychology are expanded that its data are increasing in psychology, ethics, moral philosophy are modified.

Characteristics of Thermal Variations with the Different Land Covers in an Urban Area (도시 지역에서 토지 피복에 따른 열 변이 특성)

  • Park, Sung-Ae;Kong, Hak-Yang;Kim, Seung-Hyun;Park, Sungmin;Shin, Young-Kyu
    • Ecology and Resilient Infrastructure
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    • v.3 no.1
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    • pp.46-53
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    • 2016
  • This study was conducted to analyze the effect of the different land covers of an urban park (Hyowon park) in downtown Suwon on the urban thermal variations during a hot summer. The effect of the air temperature reduction in the urban park was 4.4%-4.5% for the downtown residence (Maetan-dong). This value was about 0.8% lower than that of the outskirts residence (Sanggwanggyo-dong). The daily mean temperature, daily maximum temperature, summer day and heat wave frequency were measured under the different land covers (cement-block, grass, pine-grass, shading area and mixed forest) showed these values generally decreased under natural land cover types. Daily minimum temperature and tropical night frequency didn't seem to correlate with the land cover types. Means of thermal comfort indices (wet bulb globe temperature, heat index and discomfort index) in the shading area, mixed forest and the pine-grass types were lower than those of cement block and grass types. However the levels of those indices were equal to 'very high' or 'caution' levels in the afternoon (13:00-15:00). In the morning (06:00-08:00), thermal comfort indices of the urban park didn't correlate with land cover types. Therefore, to reduce heat stress and to improve the thermal comfort in urban parks, an increase in the area of natural land cover such as grass, forest and open spaces is required.

Studies on Thermal Oxidation of Soybean Oil -I. Changes in Some Chemical and Physical Properties of a Soybean Oil during Thermal Oxidation- (대두유의 가열산화중의 특성변화 -제 1 보 : 가열산화중의 대두유의 일부 화학적, 물리적 성질의 변화-)

  • Shin, Ae-Ja;Kim, Dong-Hoon
    • Korean Journal of Food Science and Technology
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    • v.14 no.3
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    • pp.257-264
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    • 1982
  • In the present stud changes of some chemical and physical properties of a soybean oil, aerated at 120 ml/min through a porous gas distributor and oxidized at $45^{\circ}C{\sim}180^{\circ}C$, was investigated. The results of the study were as follows: The peroxide, thiobarbituric acid, and iodine value of the soybean oil which was aerated at 120 ml/min increased rapidly as oxidation temperature exceeded over $80^{\circ}C$. The acid value of the oil increased very rapidly as the oxidation temperature passed over $160^{\circ}C$. The content of the unsaturated fatty acid of the oil decreased considerably as the oxidation temperature exceeded over $80^{\circ}C$, whereas that of the saturated fatty acid did not change appreciably. This related well to the changes of the iodine value of the oil subjected to the same experimental conditions. The viscosity and refractive index of the oil increased rapidly as the oxidation temperature passed over $180^{\circ}C$. The following linear relationship hold for the viscosity and refractive index of the oil in the present study. $$V=Aexp({\frac{E}{RT}})$$ where V=viscosity(poise), A=constant, E=activation energy for viscous flow, R=gas constant, T=oxidation temperature$(^{\circ}K)$. The following relationship also hold for the viscosity and refractive index$({n^{20}}_D)$ of the oil at the present experimental conditions. $${n^{20}}_D=1.4614+7.333{\times}10^{-5}t+2.9612{\times}10^{-3}\;InV$$ where t=temperature$(^{\circ}C)$ at which the viscosity was measured.

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A Study on the Application of the Korean Valuation Weights for EuroQoL-5 Dimension (EuroQoL-5 Dimension 한국 가중치 모형의 적용 연구)

  • Lee, Young-Hoon;Choi, Jin-Su;Rhee, Jung-Ae;Ryu, So-Yeon;Shin, Min-Ho;Kim, Jin-Hee
    • Korean Journal of Health Education and Promotion
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    • v.26 no.1
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    • pp.1-13
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    • 2009
  • Objectives: This study was conducted to estimate the health-related quality of life (HRQOL) using EuroQoL-5 Dimension (EQ-5D) and to identify its related factors among urban-dwelling adults. Methods: The data for this study were obtained from 1,134 subjects aged $20\sim91$, who participated in 'Survey on the health status and demand for health' in two cities of Korea (Dong-gu, Gwangju and Suncheon-si, Jeollanamdo). The HRQOL was measured using the EQ-5D instrument and EQ-5D index scores were calculated by two Korean valuation study model using time trade-off method. Results: The mean EQ-5D index scores for all subjects were $0.865{\pm}0.218$ (model A), and $0.921{\pm}0.170$ (model B). The EQ-5D index score was significantly different according to demographic and socioeconomic characteristics (gender, age, marital status, education, occupation, income, and health security system), self-rated health condition, health-related psychological assessments (enough sleep, fatigue rate, stress rate, and degree of satisfaction on the residence). The results of multiple linear regression showed that age, marital status, income, coverage of medical insurance, self-rated health condition, and fatigue rate were significantly related common statistical factors of HRQOL in two Korean valuation study model. Conclusion: Among the adults residing in urban environment, the HRQOL was significantly lower on the subjects with following conditions: higher age, being alone without a spouse as a result of death, divorce or separation, low income, medical aid program, poor self-rated health condition, and chronic fatigue. In order to improve the urban adults' quality of life, healthcare policy and health promotion program must be developed with considerations to factors related to the HRQOL.

Regional Commitment Index of Hospitals (의료기관 특성별 지역환자구성비)

  • Kim, kyung-Ae;Ryu, See-Won;Kim, Young-Rhang
    • Health Policy and Management
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    • v.19 no.4
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    • pp.121-139
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    • 2009
  • Objectives : The purpose of this study was to investigate regional commitment index(RGI) of hospital in Korea, and the relationship RGI and hospital characteristics, such as foundation, region, size. Therefore, we are to suggest fundamental information to make and evaluate healthcare resource policy in hospital- and government-level. Methods : The 'Patient Survey 2002(administered by Ministry of Health and Social Welfare(MOHW)' was analyzed. We selected the patient data of the hospitals above 100 beds. Then, we calculated the RGI, number of same cases divided by all cases in each hospital. By using SPSS/win ver 14.0, statistical analysis such as t-test, ANOVA, correlational and regression analysis was carried out. Results : The results are as follows. 1. Overall mean and standard deviation of RGI were revealed as 0.805${\pm}$0.225 in inpatients, and 0.871${\pm}$0.184 in outpatient. The median of inpatients' and outpatients' RGI were 0.890 and 0.933. The RGI of inpatients of private hospitals were revealed significantly higher than that of the public(public: 0.727, private: 0.822). However, outpatients' RGI was not revealed as significantly different. 2. The RGI of general specialty hospitals were significantly lower than others, therefore we could think that more inpatients and outpatients of general specialty hospitals flowed in from others province or metropolitan cities than other hospital types. 3. The RGI of hospitals holding above 400 beds were significantly lower than others in inpatients and outpatients. 5. The RGI of hospitals were significantly different among sixteen province and metropolitan cities. The RGI inpatients of Gwangju and Daejon metropolitan city were lowest sub-group(0.659, 0.664), and the RGI inpatients of Jeju was revealed as highest, 0.979. 6. Available beds, total doctors, and total employees were negatively correlated with RGI of inpatients and outpatients. 7. The significant influencing factors to RGI of inpatients and outpatients were appeared samely such as available beds, wide healthcare region, hospital size, and foundation type. Conclusions : It is considered that RGI of hospital represent competitive power in healthcare market. Also, the competitive advantage and quality of hospital clustered by characteristics could made out by RGI. Therefore, the results of this study would be useful to develop and evaluate hospital policy of individual hospital or local government.

Effects of an Inflowing Urban Stream (Wonju stream) on Epilithic Diatom Assemblages in the Lower Seom River (도시 하천(원주천) 유입이 섬강 하류 부착규조 군집에 미치는 영향)

  • Yoon, Sung-Ae;Kim, Nan-Young;Kim, Baik-Ho;Hwang, Soon-Jin
    • Korean Journal of Ecology and Environment
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    • v.43 no.2
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    • pp.232-241
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    • 2010
  • Epilithic diatom communities and water quality were monitored to evaluate the ecological impact of the inflow of Wonju-stream passing through the urban area in the Seom River Watershed. We selected the 14 sampling stations (5 main stream sites and 9 tributary sites), and collected diatom and water samples between October 2007 and September 2008, on the seasonal basis. The results indicate that most water quality parameters showed the site-specific patterns over the study, except for water temperature and dissolved oxygen. The levels of water quality parameters were highest at the site of Wonju stream, whereas the lowest in the upstream sites, and intermediate or gradually decreased in the downstream sites of the Seom river. One species, Achnanthes convergens, showed the highest biomass and frequency over the sites, while three saprophilous species-Navicula goeppertiana, Navicula subminuscula, Nitzschia palea were appeared only in Wonju Stream and other polluted sites. According to trophic diatom index (TDI) values, which were highly correlated with nutrients and EC, the study sites were classified into three classes: upstream and tributary (Class A and B), Wonju Stream (Class D), and mixed zone and downstream (Class C). A cluster analysis supported the result of TDI classification. Therefore, Wonju-stream located in populated urban area exerted the adverse ecological effects on the epilithic diatom community and water quality of the lower Seom River System, although its severity gradually decreased downstream.

Effects of Oral Myofunctional Exercise on the Oral Health in Masticatory Dysfunction (저작기능장애의 구강근기능훈련이 구강위생에 미치는 효과)

  • Oh, Na-Rae;Yoon, Sung-Uk;Jeong, Mi-Ae
    • The Journal of the Korea Contents Association
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    • v.19 no.5
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    • pp.455-463
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    • 2019
  • This study aimed to find out the effects of oral health education between the experiment group and the control group upon motivating them using oral facial program in 56 subjects including 29 members in the experiment group and 26 in the test group. With the collected data, Wilcoxon signed rank test was performed to understand the difference before and after the program. OHBI in the experiment group showed significantly higher than the control group (p<0.05), mean values after the program with $9.57{\pm}1.44$ and $8.68{\pm}1.46$ points in the experiment group and the control group, respectively. Mean QHI score in the experiment group was $1.00{\pm}.14$ points after the program while that in the test group was $1.03{\pm}.23$, demonstrating lower in the experiment group but not statistically significant. Mean scores of program satisfaction level were $4.13{\pm}.17$ and $3.94{\pm}.22$ points in the experiment group and the control group, respectively, demonstrating statistically significant. Based on the study results, the effects of oral health education using orofacial program showed the differences between the groups in dental plaque index and oral health behavior index. It is worth to use the oral facial exercise program as a tool for improving the authoring function and oral hygiene.

Vertical distribution and vascular plants on Joryeongsan Mountain in Baekdudaegan, Korea (백두대간 조령산의 관속식물과 수직분포)

  • Jung-Hyun Kim;Jin-Suk Kim;Sookyung Shin;Sung-Ae Park;Sunghyuk Park;Sung Kyung Han;Jin-Seok Kim
    • Korean Journal of Environmental Biology
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    • v.42 no.1
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    • pp.95-126
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    • 2024
  • In this study, we investigated the vertical distribution and vascular plants on Joryeongsan Mountain in Baekdudaegan, Korea. The results of four field surveys from April to September 2023 identified a total of 552 taxa, representing 491 species, ten subspecies, 43 varieties, six forms, and two hybrids in 314 genera and 101 families. The elevational distribution ranges of 360 taxa of vascular plants were also identified. Among them, 19 taxa were endemic to Korea, and two taxa were rare plants. The floristic target plants amounted to 100 taxa, specifically two taxa of grade V, seven taxa of grade IV, 25 taxa of grade III, 33 taxa of grade II, and 33 taxa of grade I. Seventy-eight taxa were northern lineage plants. In all, 29 taxa of alien plants were recorded in the investigated area, with a naturalized index of 5.3% and an urbanization index of 7.4%. Two plants disturbed the ecosystem. Species richness along the elevation showed a reversed double-hump shape with peaks at low, mid, and high elevations. The results of a cluster analysis showed a high degree of similarity between adjacent elevation sections, except in lowlands. Detrended Correspondence Analysis ordination also supported distinct groups by elevation. Warmth index values ranged from 62.1℃·month to 92.9℃·month on Joryeongsan Mountain. Our results provide primary data on vascular plants and valuable information on the current distribution ranges of plant species on Joryeongsan Mountain. These data could serve as a baseline for comparing species shifts at elevations under future climate changes.

Neuroprotective & antioxidant effects of diets high in n-6 and n-3 fatty acids in rat focal brain ischemia model (N-6와 n-3 지방산이 풍부한 식이가 뇌졸중 유발 모델에서 뇌경색 크기 및 항산화 효소계에 미치는 영향)

  • Lee, Hee-Joo;Park, Kyoung-Ae;Park, Myoung-Sook;Lee, Joung-Hee;Cheon, Sang-Eun;Cheo, Myoung-Ae;Choi, S-Mi
    • Journal of Korean Biological Nursing Science
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    • v.3 no.1
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    • pp.41-52
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    • 2001
  • This study was undertaken to investigate the effects of n-6(corn oil) & n-3(fish oil) fatty acids on infarction size and the cerebral activities of antioxidant enzyme in rat focal brain ischemia model. Weaning Sprague-Dawley rats were fed with either corn oil supplemented diet(COD, 14% corn oil) or fish oil supplemented diet(FOD, 14% menhaden oil) for 6 weeks. The right middle cerebral artery was occluded for 2 hours with a silicon rubber coated nylon surgical thread. After 24 hours of recirculation, the rats were sacrificed and brain sections were photographed using CCD camera after staining with 2, 3, 5-triphenyltetrazolium chloride for 60 minutes in room temperature. The infarcted area was measured and the volume of infarction was calculated. Catalase(CAT), superoxide dismutase(SOD) activities, and fatty acid composition in the brain were also measured. The total and corrected infarction volumes were not significantly different between FOD and COD group. The docosagexaenoic acid(DHA) and DHA content/arachidonic acid(AA) ratio of the cerebral cortex, an index of defense against lipid oxidation, were significantly increased in FOD group compared to those of COD group(p<0.05). In the left cortex(non-infarction side) as well as the right cortex(infarction side) of FOD group, CAT and Cu/Zn SOD activities were higher than those of the COD group(p<0.05). However, CAT and Cu/Zn SOD activities were not significantly different between the left cortex(non-infarction side) and the right cortex(infarction side) of both FOD and COD group. GPx activities were also not significantly different between two groups. Our results demonstrate that the brain infarction size in FOD and COD were not significantly different. However, cerebral lipid composition and antioxidant enzyme activities in FOD and COD group were different. Fish oil, a source of n-3 polyunsaturated fatty acid(PUFA) and corn oil, that of n-6(PUFA) may have a protective effect against oxidative stress induced via different mechanisms.

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