• Title/Summary/Keyword: A30

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Effects of Chronic Ethanol Administration on Folate Metabolism and Plasma Homocysteine Concentration in the Rats (만성적인 에탄올 섭취가 흰쥐의 엽산대사 및 혈장 호모시스테인 농도에 미치는 영향)

  • 임은선;서정숙;민혜선
    • Journal of Nutrition and Health
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    • v.31 no.6
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    • pp.1006-1013
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    • 1998
  • The present study was conducted to investigate the effect of different levels of ethanol ingestion on 131ate metabolism and plasma homocysteine concentration in Sprague-Dawley male rats receiving 0, 10, 30% of their caloric intake as ethanol for S weeks. Diets containing 10% ethanol had no effect on plasma and red blood cell(rbc) 131a1e. However, in rats fed a 30% ethanol diet, rbc folate increased and plasma 131ate decreased significantly, In the rats maintained first on a 30% ethanol diet for S weeks and then on a control diet for 2 weeks, the levels of plasma and rbc f31ate were normalized by withdrawal of ethanol. Urinary fo1ate excretion increased markedly in rats fed 10% and 30% ethanol diets and decreased to 51% of controls by withdrawal of ethanol. Plasma homocysteine concentration increased significantly in rats fed a 30% ethanol diet. The results suggest that chronic ingestion of ethanol increased urinary 131ate excretion markedly, which may decrease plasma 131ate and deplete liver folate.

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A Study of Below Knee Surrounding Dose depends on whether Using Collimator Shielding or not while Percutaneous Coronary Intervention (경피적 관상동맥 중재술 시 차폐 유·무에 따른 슬 하부 주변부 선량에 관한 연구)

  • Park, Jae Jin;Ko, Seong Jin;Kang, Se Sik;Kim, Chang Soo;Kim, Jung Hoon;Kim, Dong Hyun
    • Journal of the Korean Society of Radiology
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    • v.7 no.5
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    • pp.353-358
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    • 2013
  • Recently, the Percutaneous Coronary Intervention has become a main treatment for treating Coronary because of increase of Circulatory Disease. Because of this reason, the increase of intervention using radiation causes the radiation exposure to workers. Therefore, the latent radiation injury can be increased. Thus, this study/experiment measured around under knee whether using radiation collimator shielding or not. We measured the exposure does by the experiment methods which are using 60kV, 200mA, and 10ms of Automatic exposure conditions and using the major method of the Cinefluography of Coronary in our hospital. As the result of right coronary artery test cases, LAO $30^{\circ}$ when the curtains if you use lead 98.4%, $Cranial30^{\circ}$ 98.3% have a protective effect of the radiation. left circumflex coronary artery test cases, Caudal $30^{\circ}$ if the shielding effect of 90.2%, Caudal $30^{\circ}LAO$ $30^{\circ}$ 88.7% have a protective effect of the radiation. left anterior descending artery test cases, Cranial $30^{\circ}$ 98.3%, Cranial $30^{\circ}RAO$ $30^{\circ}$ 80.3%, Cranial $30^{\circ}$LAO $30^{\circ}$ 98% of the radiation has a protective effect. OS(Spider view) in the case of test Caudal $40^{\circ}LAO$ $40^{\circ}$ 71.2% appeared to have the effect of radiation shielding. For these reasons, radiation workers need to be aware on taking care of their radiation exposure by using the radiation collimator shielding even though it is uncomfortable for them.

Determination of Appropriate Sampling Time for Job Stress Assessment: the Salivary Chromogranin A and Cortisol in Adult Females

  • Hong, Ran-Hi;Yang, Yun-Jung;Kim, Sang-Yon;Lee, Won-Young;Hong, Yeon-Pyo
    • Journal of Preventive Medicine and Public Health
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    • v.42 no.4
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    • pp.231-236
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    • 2009
  • Objectives : This study was conducted to determine the appropriate sampling time of the salivary stress markers, chromogranin A (CgA) and cortisol as objective indices of job stress assessment in adult females. Methods : The subjects were 20${\sim}$39-year-old women (13 office workers, 11 sales-service workers, and 11 college students) who were eligible for the study and free of acute and chronic medical conditions. Salivary CgA and cortisol levels were determined by enzyme-linked immunosorbent assay (ELISA). Saliva samples were collected (2 $m{\ell}$ each) at 7:00, 8:00, 10:30, 12:00, 17:30, and 22:30 on a typical day. Salivary CgA and cortisol levels, according to sampling time, were compared among the three groups using general linear model. The full version of the Korean Occupational Stress Scale (KOSS), which includes socioeconomic characteristics, health behavior, workrelated characteristics, and BMI, was used to access the subjects' job stress. Multiple regression analysis of the job stressors identified by the KOSS was performed on salivary CgA and cortisol levels. Results : The salivary CgA level peaked at 7:00 (time of awakening), then decreased and were maintained at a low level throughout the day, and increased slightly at 17:30. The salivary cortisol level increased steeply within the 1st hour after awakening, followed by a gradual decrease by 12:00, and was then maintained at a low level throughout the day. The salivary cortisol levels of subjects who worked ${\leq}$5 days per week and graduated from the university were significantly lower at 8:00 (p=0.006). The salivary cortisol levels of non-smokers were significantly lower at 7:00 p=0.040) and 8:00 (p=0.003) compared to smokers. There were no significant differences in salivary CgA and cortisol levels at 10:30 and 12:00 in general characteristics. The regression coefficients on salivary CgA level were significant with interpersonal conflict at 17:30 and job insecurity at 22:30. Regression coefficients on salivary cortisol level were significant with organizational system and total job stressors at 17:30. Conclusions : We suggest that the appropriate sampling times for the salivary stress markers, CgA and cortisol, are at 7:00 (time of awakening), 8:00 (1 hour after awakening), 17:30 (early evening), and 22:30 (before sleep).

Analysis of antigenic domain of GST fused major surface protein (p30) fragments of Toxoplasma gondii (융합단백질로 발현된 톡소포자충의 주요막단백질(p30) 절편의 항원성)

  • 남호우;임경심
    • Parasites, Hosts and Diseases
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    • v.34 no.2
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    • pp.135-142
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    • 1996
  • Antigenic domain of jai or surface protein (p30) of Toxoplosmc Sondii was analyzed after polymerase chain reaction (PCR) of its gene fragments. Hydrophilic or hydrophobic moiety of amino acid sequences were expressed as glutathione S-transferase (G57) fusion proteins. Fragments of p30 gene were as follows: 737, total p30 open reading frame (ORF) ; S28, total ORF excluding N-terminal signal sequence and C-terminal hydrophobic sequence; Al9, N-terminal 2/3 parts of A28; A19, N-terminal 2/3 of S28; P9, C-terminal 2/3 part of S28; Z9. middle 1/3 of S28; and 29, C-terminal 1/3 of S28. respectively. Primer of each fragment was synthesized to include clamp sequence of EcoR I restriction site. PCR amplified DNA was inserted info GST (26 kDa) expression vector, PGEX-47-1 to transform into Escheri,hia coei (.JM105 strain). G57 fusion proteins were expressed with IPTG induction as 63. 54, 45, 45, 35, 36. and 35 kDa proteins measured by SDS-PAGE. Each fusion protein was confirmed with G57 detection kit. Western blot analysis with the serum of a toxoplasmosis patient revealed antigenicity in proteins expressed by T37. S28, and Al9 but not those by Pl8. X9, Y10, and Z9. Antigenicity of p30 seems to be located either in N-terminal 115 part in the presence of middle 1/3 part or in the oligopeptides between margins of the first and second 1/3 parts.

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Effect of Bisphenol A Administration on Semen Characteristic and Organ Weight in Mice (Bisphenol A 투여가 웅성 생쥐의 정액성상과 장기무게에 미치는 영향)

  • 김용배;박동헌;박춘근;김정익;정희태;양부근
    • Korean Journal of Animal Reproduction
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    • v.26 no.1
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    • pp.25-32
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    • 2002
  • This study were performed to investigate the effect of Bisphenol A(BPA) administration on semen characteristic and body or organ weight in mice. In BPA administration for 15 days or 30 days, sperm concentration and viability were lower in group treated with BPA than in control group. The proportion of sperm abnormality were significantly(P<0.05) increased in groups administrated with BPA for 15 or 30 days than in control group. The administration of BPA in mice didn't affect the body and reproductive organ weight such as testis, epididymis, vasicular gland and coagulatin gland. The spleen weight were significantly affect, but liver and kidney weight were not affect in BPA administration groups for 15 days or 30 days This studies indicate that the short or long term BPA administration in mice were noxious effects on the semen characteristics and organ weight, but didn't affect body weight and reproductive organs.

Potential Interference of Electric Equipments on Radio Service below 30MHz (30MHz 이하 무선 서비스에 대한 전자기기의 잠재적 간섭 영향)

  • Yun, Hye-Ju;Lee, Il-Kyoo
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.13 no.2
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    • pp.269-273
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    • 2013
  • This paper analyzed a potential interference of electric equipments on radio service below 30MHz through an experiment with a PDP(Plasma Display Panel) TV and a RF(Radio Frequency) light bulb in an anechoic chamber. The radiation levels of the PDP TV and the RF light bulb are measured and a combined interference is calculated on the basis of the experimental value. As a result, the combined interference signal level is increased according to the number of interferer. The possibility of a potential interference from electric equipments on radio service below 30MHz is realized through comparison between the measured radiation value of electric equipments and the CISPR(International Special Committee on Radio Interference) 11 limit.

Variable amplitude fatigue test of M30 high-strength bolt in bolt-sphere joint grid structures

  • Qiu, Bin;Lei, Honggang;Yang, Xu;Zhou, Zichun;Wang, Guoqing
    • Steel and Composite Structures
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    • v.33 no.3
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    • pp.433-444
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    • 2019
  • Fatigue failure of a grid structure using bolt-sphere joints is liable to occur in a high-strength bolt due to the alternating and reciprocal actions of a suspension crane. In this study, variable amplitude fatigue tests were carried out on 20 40 Cr steel alloy M30 high-strength bolts using an MTS fatigue testing machine, and four cyclic stress amplitude loading patterns, Low-High, High-Low, Low-High-Low, and High-Low-High, were tested. The scanning electron microscope images of bolt fatigue failure due to variable amplitude stress were obtained, and the fractographic analysis of fatigue fractures was performed to investigate the fatigue failure mechanisms. Based on the available data from the constant amplitude fatigue tests, the variable amplitude fatigue life of an M30 high-strength bolt in a bolt-sphere joint was estimated using both Miner's rule and the Corten-Dolan model. Since both cumulative damage models gave similar predictions, Miner's rule is suggested for estimating the variable-amplitude fatigue life of M30 high-strength bolts in a grid structure with bolt-sphere joints; the S-N fatigue curve of the M30 high-strength bolts under variable amplitude loading was derived using equivalent stress amplitude as a design parameter.

Change in Palliative Performance Scale (PPS) Predicts Survival in Patients with Terminal Cancer

  • Oh, Jee Hye;Lee, Yong Joo;Seo, Min Seok;Yoon, Jo Hi;Kim, Chul Min;Kang, Chung
    • Journal of Hospice and Palliative Care
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    • v.20 no.4
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    • pp.235-241
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    • 2017
  • Purpose: The Palliative Performance Scale (PPS) is a widely used prognostic tool in patients with advanced cancer. This study examines the association between changes in PPS score and survival in patients with advanced cancer. Methods: We identified a cohort of 606 inpatients who died at a Korean university hospital's hospice/palliative care center. For each patient, the PPS score was measured twice according to a standard procedure: 1) upon admission, and 2) three days after admission (D3). "Change on D3" was defined as a difference between initial PPS and PPS on D3. We used a Cox regression modeling approach to explore the association between this score change and survival. Results: The changes in scores were associated with survival. A score change of >30% yielded a hazard ratio for death of 2.66 (95% CI 2.19~3.22), compared to a score change of ${\leq}30%$. PPS of ${\leq}30$ on D3 also independently predicted survival, with a hazard ratio of 1.67 (95% CI 1.38~2.02) compared to PPS of >30. Conclusion: A change of over 30% in PPS appears to predict survival in hospitalized patients with terminal cancer, even after adjustment for confounders. Changes in PPS may be a more sensitive indicator of impending death than a single PPS measured on the day of admission in terminal cancer patients. Further prospective study is needed to examine this important finding in other populations.

Establishment of Comparison Calibration Equipment for Infrared-radiation Thermometers Below ℃ (℃ 이하 적외선 복사온도계 비교 교정장치 구축)

  • Yoo, Yong Shim;Kim, Bong-Hak
    • Korean Journal of Optics and Photonics
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    • v.29 no.2
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    • pp.70-76
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    • 2018
  • Comparison calibration equipment for infrared-radiation thermometers below $0^{\circ}C$ has been established, using a TRT2 (transfer radiation thermometer 2, HEITRONICS) as a transfer standard and an ME30 (Model: ME30, HEITRONICS) as a variabletemperature blackbody. The TRT2 was calibrated using three fixed points (Ice ($0.01^{\circ}C$), In ($156.5985^{\circ}C$), and Sn ($231.928^{\circ}C$)) and the Planckian Sakuma-Hattori equation, and including the interpolation and extrapolation errors at $-50^{\circ}C$ in the uncertainty. The pneumatic lid is installed upon opening of the ME30 and is opened for only 30 seconds for measuring the radiation temperature, which prevents formation of ice in the ME30 and also reduces the calibration time to half. The farther away from the $0{\sim}232^{\circ}C$ region, the larger the uncertainty of the comparison calibration equipment becomes. The expanded uncertainty of the comparison calibration equipment was estimated as 0.26 K at $-20^{\circ}C$.

A Study on the Changes in Upper Body Sizes and Body Types of 30-50's Adult Men (30대 - 50대 성인남성의 상반신 신체 치수 및 체형 유형 변화 연구)

  • Kwon, Dongkuk;Lee, Soyoung
    • Journal of Fashion Business
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    • v.25 no.4
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    • pp.36-60
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    • 2021
  • This study aimed to provide basic data for establishing a sizing system for menswear by investigating body size changes and body shapes in adult men in their 30s to 50s. Data on 52 different upper body categories collected from 4,314 people during the 5-7th Size Korea surveys were analyzed. The waist height, hip height, torso and arm lengths, and torso and upper limb circumferences increased while the arm joint sizes decreased. According to factor analysis, factors 1 and 2 referred to 'the horizontal size of the upper body and limbs' and the 'torso height and upper limb length', respectively, while factors 3 and 4 represented 'shoulder size' and 'upper body length' respectively. In clustering analysis, types 1 and 2 were 'short and fat' and 'tall and thin,' respectively, while types 3 and 4 represented 'tallest and chubby' and 'shortest and small' respectively. Torso length increased in the 30 to 40s in type 1 while torso circumference increased in the 30s and late 40s in type 2. In type 3, shoulders got bigger in the 30s. In type 4, torso circumference increased in the early 30s, and torso length increased in the late 40s. 'Thin' was a typical body shape in the early 30s. Among early 40s men, distribution evolved from 'small' to 'thin.' In the late 40s, while the percentage of 'small' decreased, the ratio of 'obese' increased. In the 50s, 'small' was the most common.