• Title/Summary/Keyword: A20

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Characterizing a full spectrum of physico-chemical properties of (20S)-and (20R)-ginsenoside Rg3 to be proposed as standard reference materials

  • Kim, Il-Woung;Sun, Won Suk;Yun, Bong-Sik;Kim, Na-Ri;Min, Dongsun;Kim, Si-Kwan
    • Journal of Ginseng Research
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    • v.37 no.1
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    • pp.124-134
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    • 2013
  • The authentication of the physico-chemical properties of ginsenosides reference materials as well as qualitative and quantitative batch analytical data based on validated analytical procedures is a prerequisite for certifying good manufacturing practice (GMP). Ginsenoside Rb1 and Rg1, representing protopanaxadiol and protopanaxatriol ginsenosides, respectively, are accepted as marker substances in quality control standards worldwide. However, the current analytical methods for these two compounds recommended by Korean, Chinese, European, and Japanese pharmacopoeia do not apply to red ginseng preparations, particularly the extract, because of the relatively low content of the two agents in red ginseng compared to white ginseng. In manufacturing fresh ginseng into red ginseng products, ginseng roots are exposed to a high temperature for many hours, and the naturally occurring ginsenoside Rb1 and Rg1 are converted to artifact ginsenosides such as Rg3, Rg5, Rh1, and Rh2 during the heating process. The analysis of ginsenosides in commercially available ginseng products in Korea led us to propose the inclusion of the (20S)- and (20R)-ginsenoside Rg3, including ginsenoside Rb1 and Rg1, as additional reference materials for ginseng preparations. (20S)- and (20R)-ginsenoside Rg3 were isolated by Diaion HP-20 adsorption chromatography, silica gel flash chromatography, recrystallization, and preparative HPLC. HPLC fractions corresponding to those two ginsenosides were recrystallized in appropriate solvents for the analysis of physico-chemical properties. Documentation of those isolated ginsenosides was achieved according to the method proposed by Gaedcke and Steinhoff. The ginsenosides were subjected to analyses of their general characteristics, identification, purity, content quantification, and mass balance tests. The isolated ginsenosides showed 100% purity when determined by the three HPLC systems. Also, the water content was found to be 0.534% for (20S)-Rg3 and 0.920% for (20R)-Rg3, meaning that the net mass balances for (20S)-Rg3 and (20R)-Rg3 were 99.466% and 99.080%, respectively. From these results, we could assess and propose a full spectrum of physico-chemical properties of (20S)- and (20R)-ginsenoside Rg3 as standard reference materials for GMP-based quality control.

Synthesis and Characterization of Interfacial Properties of Sorbitan Laurate Surfactant (Sorbitan Laurate 계면활성제 합성 및 계면 특성에 관한 연구)

  • Lee, Seul;Kim, ByeongJo;Lee, JongGi;Lim, JongChoo
    • Applied Chemistry for Engineering
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    • v.22 no.1
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    • pp.37-44
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    • 2011
  • The critical micelle concentration (CMC) of sorbitan laurate SP 20 surfactant in this paper was near $7.216{\times}10^{-4}mol/L$ and the surface tension at CMC was about 26.0 mN/m, which showed higher CMC and lower surface tension than those of octylphenol ethoxylate octylphenol ethoxylate (OPE) 10 surfactant. Dynamic surface tension measurement using a maximum bubble pressure tensiometer showed that the adsorption rate at the interface between air and surfactant solution was found to be slower with SP 20 surfactant, presumably due to a low mobility of SP 20 surfactant monomer. The contact angle of SP 20 surfactant solution was observed to decrease with an increase in surfactant concentration and showed a larger value than that of OPE 10 surfactant solution. Half-life time for foams generated with 1 wt% surfactant solution was also larger with SP 20 surfactant, which indicated higher foam stability with SP 20 surfactant. Dynamic behavior study reveals that the solubilization of n-decane oil was much lower with SP 20, which is in good agreement with experimental results of foam stability, contact angle and CMC. Dynamic interfacial tension measurement by a spinning drop tensiometer shows that interfacial tensions at equilibrium condition in both systems were almost the same but the time required to reach equilibrium was longer with SP 20.

The Quality Characteristics of Soy Cutlets Using Textured Soy Protein Treated with Different Enzymes (효소처리를 달리한 조직대두단백을 이용하여 제조한 콩까스의 품질특성)

  • Kim, Eun-Bi;Kim, Eun-Joo;Lee, Han-Na;Lee, Min-Kyoung;Oh, Jong-Shin;Kim, Sun-Ok;Lee, Sook-Young
    • Journal of the Korean Society of Food Culture
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    • v.23 no.4
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    • pp.507-513
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    • 2008
  • The development of soy cutlets containing textured soy protein (TSP) as a meat analog was studied. In order to decrease the beany flavor and to increase the texture, TSP was treated with 0.3% Flavourzyme or 0.1% Protamex for 10 or 20 min, respectively. The degree of hydrolysis for TSP treated with Protamex was higher than that treated with Flavourzyme. Hydrolysis was observed to increase as the reaction time was increased for both Flavourzyme and Protamex. The water holding capacity of TSP treated with Protamex for 10 min was the highest, and that treated with Flavourzyme for 20 min was similar to that of Protamex treatment for 20 min. The oil binding capacity of TSP treated with Protamex for 20 min was the highest. The hardness of the soy cutlets using TSP treated with Flavourzyme for 10 min was higher than that treated for 20 min, while that of Protamex treated for 20 min was higher than that treated for 10 min. The cohesiveness of the soy cutlets using TSP treated with Flavourzyme or Protamex for 10 min was higher than those treated for 20 min. The chewiness of the soy cutlets treated with Flavourzyme for 10 min was higher than for those treated for 20 min, while those treated with Protamex for 20 min was higher than those treated for 10 min. The springiness of TSP treated with Flavourzyme for 20 min was higher than those treated for 10 min, and higher than those treated with Protamex for 10 or 20 min. For sensory evaluation, the beany flavor of the soy cutlets treated with Protamex for 20 min was the weakest. The flavor and chewiness of both a pork cutlet and a soy cutlet treated with Protamex for 20 min were the best. In the overall quality, soy cutlets treated with Protamex for 20 min was the most desirable. In conclusion, soy cutlets treated with 0.1% Protamex for 20 min could be a reasonable substitute of pork cutlets.

A Study for Mechanical Property for A516-60, A283-C, A285-C and SB410 materials under Low Temperature (저온영역에서의 A516-60, A283-C, A285-C, SB410 소재 특성 평가)

  • Oh, Jung-Soo;Lee, Hee-Bum;Lee, Bong-Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.9
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    • pp.405-411
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    • 2019
  • In this study, tensile tests were carried out on materials (A516-60, A283-C, A285-C, and SB410) for structural and pressure vessels at temperatures of $20^{\circ}C$, $-20^{\circ}C$, and $-40^{\circ}C$, and the changes in the mechanical properties were analyzed. Compared to the results at $20^{\circ}C$, the average yield stress increased by 6.4% and 7.5% at $-20^{\circ}C$ and $-40^{\circ}C$ for A516-60, while the average tensile stress increased by 1.3% and 4.1%, respectively. The average elongation decreased by 4.7% and 20.4% at these temperatures. In the case of A283-C, the average yield stress increased 8.8% and 9.8%, the average tensile stress increased by 4.1% and 5.9%, and the average elongation rate decreased by 7.4% and 9.9% at $-20^{\circ}C$ and $-40^{\circ}C$, respectively. For A285-C, the average yield stress increased by 1.8% and 8.6%, and the average tensile stress increased by 2.6% and 5.3%, respectively, but there was little change in the average elongation. Finally, for SB410, the average yield stress increased by 7.1% and 11.8%, the average tensile stress increased by 4.3% and 5.5%, but the average elongation rate decreased by 8.7% and 13.5%, respectively.

Unlocking the Future of a Prosperous Green Globe: With a Focus on the G-20 STI Summit

  • Choi, Young-sik
    • STI Policy Review
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    • v.1 no.3
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    • pp.17-24
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    • 2010
  • Energy consumption is the largest contributing factor for the increase of $CO_2$ emissions and amounts for almost 85% of all emissions. The future energy consumption of Korea is projected to grow exponentially despite its heavy dependence on imported energy that represents 97% of its total energy supply. According to a recent OECD report the carbon emission level of Korea is currently ranked 9th in $CO_2$ emissions, and is growing by almost 3% every year. Against this background, the Korean government introduced the "low carbon green growth" policy in 2008. As the global challenges intensified in the wake of the world economic crisis, Korea has been working hard in raising the visibility of its efforts at the club governance meetings, in particular the G-20 summit. Because of cooperative efforts with major member countries, the G-20 summit agenda has been significantly diversified to include long-term issues such as climate change, development issues, and global health. To achieve an effective green recovery for a new green world economic order, the G-20 summit leaders should concentrate on a strategy of establishing green governance for a global STI cooperation. Korea as the host country is poised to leverage the Seoul G-20 summit to catalyze global efforts toward a new green economic order.

Determination of Hyperin in the Fruits of Acanthopanax Species by High Performance Liquid Chromatography

  • Lee, Jeong-Min;Kim, Hye-Min;Lee, Su-Llim;Han, Saem;Cho, Seon-Haeng;Lee, Sang-Hyun
    • Natural Product Sciences
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    • v.16 no.1
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    • pp.39-42
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    • 2010
  • The content of hyperin in Acanthopanax species was determined by high performance liquid chromatography (HPLC). Hyperin was quantified by a reverse-phase column with elution program [initially gradient solvent (acetonitrile : water = 85 : 15 to 80 : 20 for 20 min), then isocratic solvent (acetonitrile : water = 80 : 20 for 20 min), and finally gradient solvent (acetonitrile : water = 80 : 20 to 65 : 35 for 20 min)]. UV detection was conducted at 210 nm. The content of hyperin in the fruits of Acanthopanax was measured in the species A. chiisanensis (2.04 mg/g), A. sessiliflorus (1.13 mg/g), A. divaricatus (0.98 mg/g), A. koreanum (0.75 mg/g) and A. senticosus (0.05 mg/g). The content of hyperin in A. chiisanensis was higher than that of other Acanthopanax species.

Effects of Protected Conjugated Linoleic Acid Supplementation on Milk Fatty Acid in Dairy Cows

  • Piamphon, N.;Wachirapakorn, Chalong;Wanapat, M.;Navanukraw, C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.1
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    • pp.49-56
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    • 2009
  • The objective was to determine the effects of supplementation of protected conjugated linoleic acid (CLA), CLA-20 comprising 10% each of cis-9, trans-11 and trans-10, cis-12, on milk production and fatty acid profiles in plasma and milk in lactating dairy cows. Five mid-lactation, multiparous crossbred Holstein Friesian cows with average 402${\pm}$20 kg BW were used in a 5${\times}$5 Latin square design for 21-d periods. Cows were given a total mixed ration (TMR) and supplemented with CLA-20 at 0, 20, 40, 80 and 160 g/d. The results showed that dry matter intake depression occurred in cows supplemented with CLA-20 at 160 g/d. Milk production slightly increased when CLA-20 supplementation was at 20, 40 and 80 g/d. However, 3.5% fat-corrected milk (FCM) was not affected by CLA-20 supplementation. Increased levels of CLA-20 supplementation resulted in a significantly decreased percentage of milk fat. Plasma concentrations of fatty acid were not altered by the amounts of CLA-20 supplementation except for the concentration of trans-10, cis-12 CLA. For all dietary treatments, percentages of fatty acids (C4:0, C6:0, C8:0, C13:0, C14:0 C14:1 C15:0 C15:1 C16:0, C16:1, C18:1n9t, C18:2n6t, C18:2n6c, C20:0, C18:3n6, C18:3n3, C20:1 and C20:3n6) in milk fat were similar. Concentrations of C10:0, C11:0, C12:0 and C18:1n9c were decreased cubically and C18:0 was elevated linearly (p<0.01) according to the increased amounts of CLA-20 supplemented. The linear increase was observed for cis-9, trans-11 CLA (0.62, 1.17, 1.94, 1.87 and 1.82% of total fatty acid), trans-10, cis-12 CLA (0.01, 0.63, 0.67, 0.93 and 0.95% of total fatty acid) and total CLA (0.80, 2.25, 3.16, 3.97 and 3.94% of total fatty acid) in milk fat from 0 to 160 g/d of CLA-20 supplement. In conclusion, concentration of cis-9, trans-11 CLA in milk fat was concomitantly elevated at an increasing rate with the increased amounts of CLA-20. Based on the results in this study, supplementation of CLA-20 at 80 g/d optimally enhanced total CLA in milk fat.

Effect of Dietary Bacillus sp. Inoculated Feather Meal on the Performance and Carcass Characteristics in Finishing Pigs (Bacillus sp. 접종 우모분이 비육돈의 생산성과 도체특성에 미치는 영향)

  • Kim, J.H.
    • Journal of Animal Science and Technology
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    • v.47 no.4
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    • pp.525-536
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    • 2005
  • This study was carried out investigate the effect of replacing soybean meal with feather meal or Bacillus sp. inoculated feather meal in finisher pig diets on the performances, and amino acid composition and carcass characteristics of pork. One hundred fifty pigs were randomly allotted to five dietary treatments (① control, basal diet; ② BSM (bacillus sp. inoculated soybean meal) 10, 10% of soybean meal was replaced with bacillus sp. inoculated feather meal; ③ BSM 20, 20% of soybean meal was replaced with bacillus sp. inoculated feather meal; ④ CSM (conventional soybean meal) 10, 10% of soybean meal was replaced with conventional feather meal and ⑤ CSM 20, 20% of soybean meal was replaced with conventional feather meal) in a 70-days feeding trial. In overall period, body weight gain of BSM 20 (0.95kg) was higher (P<0.05) than those of CSM 10 (0.80kg) and CSM 20 (0.81kg), respectively. And feed conversion of BSM 20 (2.94) was lower (P<0.05) than that for other treatments (3.06-3.41). Carcass weight of BSM 10 (81.84kg) and BSM 20 (83.77kg) were greater (P<0.05) than those of CSM 10 (74.75kg) and CSM 20 (76.07kg), respectively. Proportion of grade A carcass in BSM 20 (35.03%) was higher compared to the control treatment (32.78%). CIE L* of meat color was lowest in the BSM 10 (45.56), and hightest (P<0.05) in the CSM 20 (59.96). In addition CIE a* of meat color of control (9.35) highest (P<0.05) than those of BSM 10 and BSM 20 were 7.56 and 7.42, respectively.

Study on the Perception of Somatotype for Men's Lower Body in the 60s and the 20s (60대와 20대 남성의 하반신 체형에 대한 인식 연구)

  • Lee, Young-Ju;Kim, Hyun-Jin
    • Korean Journal of Human Ecology
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    • v.12 no.5
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    • pp.777-786
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    • 2003
  • The purpose of this study was to compare the perception of men's lower body shape in the 60s with that in the 20s. On hundred and seven men in the 60s and 178 men in the 20s participated in the survey and measurements. The results were as follows : 1. It was perceived that men in the 60s had broader girth but lighter weight than men in the 20s. The research revealed that men in the 60s was more satisfied with their lower body shape than men in the 20s. 2. It was also found that the ideal size of men in the 60s was broader in the girth of their waist and hip, shorter in their height, and lighter in their weight compared to men in the 20s. 3. It showed a difference in the satisfaction with their body shape between men in the 60s and the 20s. The satisfaction with their lower body shape of men in the 60s was more affected by their perception than by their real measured size. On the other hand, the satisfaction of men in the 20s was affected by their perception as much as by their measured size. 4. If we look at the perception and satisfaction in relation with their body types, we found that there was a difference in the girth of their waist, abdomen, hip, and weight depending on their body types. And men in the 20s showed greater differences in their perception and satisfaction depending on their body types, compared to men in the 60s. 5. The measured size of men in the 20s had greater differences depending on their body types than that of men in the 60s. On the contrary, the ideal size of men in the 60s had greater differences than that of men in the 20s.

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A Study on Output Voltage Stabilization of 20W Class Multi-output QR Flyback Converter for Auxiliary Power (20W급 보조전원용 다출력 QR 플라이백 컨버터의 출력전압 안정화에 관한 연구)

  • Yoo, Jeong Sang;Gil, Yong Man;Kim, Hyun Bae;Ahn, Tae Young
    • Journal of the Semiconductor & Display Technology
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    • v.20 no.3
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    • pp.157-160
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    • 2021
  • In this paper, a 20W class multi-output QR flyback converter for auxiliary power supply was designed to stabilize 4 output voltages, and the efficiency and load characteristics were compared and analyzed. It was checked if each output affects other output characteristics through experiment. As a result, the experimental circuit reached a high efficiency of 82.5% or more at a load power of over 20W, and the maximum power loss was 2.6W. Consequently, it was confirmed that all of 4 output voltages of the multi-output QR flyback converter constructed in this paper were stabilized within 0.5% in full-load range, and each output was independently controlled in an electrically isolated state.