• The Journal of the Korean bone and joint tumor society
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• v.18 no.1
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• pp.20-27
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• 2012

Purpose: The chemokine receptor CXCR4 has been reported to be aberrantly expressed in human cancer and has been shown to participate in cancer metastasis. We compared the expression of CXCR4 in conventional high-grade and low-grade central osteosarcomas, and determined if an association between CXCR4 expression and prognosis could be made. Materials and Methods: We performed the immunohistochemistry for CXCR4 in a total of 63 patients with osteosarcoma and determined the relationships according to the clinicopathologic variables and overall survival rates. Results: CXCR4 was detected in 76.3% of conventional high-grade osteosarcoma patients and in 36% of low-grade central osteosarcomas. Diffuse expression was noted in 47.4% of the high-grade osteosarcomas and all low-grade cases were focal positive. CXCR4 expression was significantly correlated with histologic grade (p<0.0001). While overall survival rate was reduced significantly with increased CXCR4 expression (p=0.0058), higher histologic grade (p<0.0001), and younger age (p=0.0140), survival rate did not correlate with gender, tumor size, or AJCC stage. Conclusion: Our results suggest that CXCR4 expression is associated with higher-grade tumors and with poor prognosis for osteosarcoma patients.

• Journal of the Korean Institute of Educational Facilities
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• v.13 no.4
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• pp.15-23
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• 2006

The purpose of this study is to establish the objective deterioration grades and evaluation criteria of building equipment system of educational facilities available for reasonable maintenance and remodeling of them. For the purpose of it, the actual conditions of building equipment systems of the 148 buildings of 84 middle and high schools in Seoul 20 years after construction are investigated and surveyed through one-on-one interviews and questionnaires. And, deterioration grades of them are estimated by the evaluation criteria which is proposed in this study. As a result of this study, the 10 deterioration grades and the 4 evaluation criteria of the 6 performances of building equipment system, which are heating and cooling, water supply and drainage, hot water supply and electrical power performance, are suggested. And, as a result of the survey, it showed that 24% of the investigated school buildings were estimated C grade which needs partial remodelling, and 51% of the school buildings were estimated D grade which needs extensive remodelling. And, 25% of the school buildings were estimated E grade which needs overall remodelling or alteration of building equipment system.

• Journal of Chest Surgery
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• v.27 no.11
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• pp.902-906
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• 1994

Between May 1991 and August 1993, 16 patients underwent repair of complete atrioventricular septal defect without another major anomaly at Cardiovascular Center,Yonsei University College of Medicine. Ages of the patients ranged from 3 months to 38 years with a mean of 42 months. Among 16, 10 patients[63%] are associated with Down`s syndrome. All patients underwent primary repair except and one who received had been repaire of coactation of aorta and patent ductus arteriosus 2 month before. Preoperative mitral valve regurgitation [MR] was evaluated with Doppler echocardiography and angiography which revealed absent or grade I in 1, grade II in 8, grade III in 4, and grade IV in 3. Operative technique was performed under the moderate hypothermic cardiopulmonary bypass with crystalloid cardioplegia. Intraoperative echocardiography was performed epicardial approach [n=7] in the operative table or transthoracic approach [n=9] at intensive care unit. In all patients except 3, MR were improved. But in 3 patients, was not improved or exagerated comparing preoperative one. All of them were died.One patient was showed MR grade IV in intraoperative echocardiography, we re-repaired atriventricular valve with cardiopulmonary bypass. During follow-up period [at a mean of 11 months after repair], doppler echocardiography was performed in all patients. The follow up echocardiography revealed that the degree of MR in immediate postoperative period was not changed except in two patients in whom it was aggravated. Thus it seems that intraoperative and early postoperative echocardiography was employed important role of survival and can be predictable for long term results.

• Journal of Korean Neurosurgical Society
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• v.38 no.5
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• pp.350-354
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• 2005

Objective : The aim of this study is to assess the immediate and long-term efficacy of percutaneous vertebroplasty for treating painful vertebral osteoporotic fractures. Methods : A retrospective review of 149patients who had undergone 167 vertebroplasty procedures for osteoporotic fractures was performed. Clinical, radiologic, and procedural datas were analyzed as parameters of prognostic significance, including age, sex, bone marrow density score, symptom duration, bone cement filling grade, number of fractured vertebrae, compression grade of vertebrae, leakage of bone cement, volume of bone cement injected and complications. Results : In 158 of the 167 procedures assessed, immediate pain relief was obtained [94.6%]. The extent of collapse of the vertebral body was assessed as a parameter for prognostic significance [p=0.015]. Three months postoperatively, no improvement of the pain was observed in four of the 167 procedures that had undergone the vertebroplasty [2%]. At long-term follow-up, the improvement of pain was not correlated with the compression grade of vertebrae [p=0.420]. Conclusion : The immediate outcome of vertebroplasty are less effective in vertebrae more collapsed.

• Journal of Korean Clinical Health Science
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• v.2 no.3
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• pp.158-166
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• 2014

Purpose. This study pursued the way for the effective application of the differentiated charge (Nursing grading system) by the nursing manpower which is performed for the nursing service quality improvement to the in-patients in Korea and the minimum employment problem solution of nurses. Methods. For this matter, the status of the nursing grade for 1,452 hospitals (44 high class general hospitals, 259 general hospitals, 265 hospitals, 59 oriental medicine hospitals and 825 recuperation hospitals) was identified which were registered in the Health Insurance Review and Assessment Service in March 2011 status quo. Results. In the most nursing grade by the kind of medical institutions, 70.5% of the nurses were third-graded in upper general hospitals, 38.1% were sixth graded in general hospitals, 62.7% were seventh-graded in oriental medicine hospitals and 40.4% were first-graded in recuperation hospitals. In the nursing grade by the scale of hospitals (in terms of the number of beds), there was a significant difference in general hospitals, but there was no significant difference between oriental medicine hospitals and recuperation hospitals. In the nursing grade by the location of hospitals and the foundation type of hospitals, there was a significant difference between general hospitals and recuperation hospitals. Conclusion. For the effectiveness of applying differentiated nursing fees by the number of nurses, it seems necessary to consider adjusting the present differentiated inpatient-charge system for the better so that small and medium-sized hospitals may induce more nurses.

• Women's Health Nursing
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• v.18 no.3
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• pp.200-208
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• 2012

Purpose: This study was aimed to examine the gap between predicted cesarean section rate and real cesarean section rate and it's determining factors of 44 tertiary hospitals. Method: This study is a cross-sectional analysis using the data of 25,623 deliveries in 2009 drawn from homepage of Health Insurance Review and Assessment Service. Data were analyzed with t-test, F-test, Scheff$\acute{e}$ test, and logistic regression. Result: There were statistically significant differences in the gap of cesarean section rate (more gap indicates higher quality of delivery) by grade of nurse staffing and delivery cases. Hospitals with nurse staffing grade 1 to 2 had more possibility to be classified into higher grade in quality of delivery (OR 5.67, 95% CI 1.07-30.08). Also hospitals with over 500 delivery cases had more possibility be classified into higher grade in quality of delivery (OR 4.92, 95% CI 1.14-21.23, respectively). Conclusion: The finding suggests that grade of nurse staffing may influence the real cesarean section rate because nurses do a vital role to prevent unnecessary cesarean section. Further study is required to provide evidence that nurse staffing influence on patient outcome and cost-effectiveness in order to obtain adequate number of nursing staffs.

• Journal of Nutrition and Health
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• v.21 no.5
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• pp.333-347
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• 1988

The purpose of the present study was to investigate the relationship between nutrient status, and bone mineral state which influenced by aging process. The subjects were 196 people over 65 years old(male 72, female124). The present dietary intake was estimated by the 24-hr, recall method, and individual dietary history concerning consumption of meat, fish and dairy products was obtained by questionaires. The syndrome of senility including seniliy was evaluated according to "Cornell Medical Index". The five subjects who showed 'Good' grade in bone senility, and five subjects who showed 'Risk' and 'Danger' grade were selected and their spine and femur bone density was measured by "Dual Photon Absorptiometry". The bone density measurement showed that the subjects with 'Good' grade in bone senility had bone density above that of normal person, and their nutrient status were satisfactory, whereas the subjects with 'Risk' and 'Danger' grade in bone senility had severe osteoporotic pattern, and their nutrient status were very poor. The food consumption score showed that the subject with higher intake of meat rather than milk had good grade in bone senility (p<0.05). Therefore, past meats consumption can be considered to be a significant factor in the present bone status. The nutrient intakes appeared to be significant factors in bone status in male, whereas there was little effect of nutrients intakes in female. Therefore, the risk of osteoporosis can increase as syndrome of bone senility and nutrient intakes were worse, and its is possible to evaluate bone status and predict osteoporosis simply from informations concerning syndrome of bone senility and nutrient intakes in old population over 65.

• Journal of Families and Better Life
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• v.28 no.2
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• pp.181-192
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• 2010

The purpose of this paper is to observe the influence of internet addiction, interpersonal anxiety and self-control in messenger immersion. Questionnaires regarding internet addiction, interpersonal anxiety and self-control were administered to 600 6th grade elementary school students and 2nd grade middle school students in the province of Seoul, South Korea. A total of 592 questionnaires were collected. As statistical methods, Cronbach's, multiple linear regression analysis and stepwise regression with SPSS 10.0 were used. The main results of the study were as follows - 1) In observing the degree of messenger Immersion by the sex and grade of the adolescent, the results show that the percentage in the top group and the middle group appears higher for school boys than school girls as well as 6th grade school-children rather than for 2nd grade middle school students. 2) A difference was noted between the messenger immersion factor in school-boys' and that in school-girls'.

• Journal of Korean Public Health Nursing
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• v.31 no.1
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• pp.162-177
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• 2017

Purpose: The purpose of this study was to investigate the degree of obesity and dietary self-efficacy scale and to identify factors that affect obesity in upper-grade elementary school students. Methods: A total of 458 fifth to sixth grade elementary school students in Seoul and Chuncheon city, and rural areas of Gangwon Province, were included in this study. The data was analyzed by descriptive statistics, ${\chi}^2$-test, t-test, ANOVA, and logistic regression. Results: The results revealed significant differences in the obesity region, perceived body image, experience of weight loss, family member of mother's age, mother's job and father's job between 'not obesity group' and 'obesity group'. The logistic regression analysis revealed that obesity was related with gender, region, and perceived body image. Conclusion: Gender, region, and perceived body image showed a relationship with obesity in upper-grade elementary school students. Thus, to develop obesity management program for upper grade elementary school students, we should be considered the gender, region, and perceived body image should be considered.

• The Journal of Internal Korean Medicine
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• v.31 no.2
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• pp.388-394
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• 2010

Objectives : This study reports two cases of grade four pressure ulcer patients mainly treated by pharmacopuncture Soyeom and Taklisodok-eum. Methods : Two patients with grade four pressure ulcers at the oriental medicine hospital of Woosuk University were treated by pharmacopuncture Soyeom and herbal medicine Taklisodok-eum. Soyeom was treated once a day and Taklisodok-eum was given three times a day. We then observed the patients' appearances of pressure ulcer and changes of blood test results. Results and Conclusions : After ten days or three months each, wound sizes were reduced, tissue regeneration was accelerated and blood tests were improved. In conclusion, it is our belief that pharmacopuncture and herb medicine are effective to treat grade four pressure ulcers, and future studies will be required to ascertain this method on grade four pressure ulcers.