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Management of the Most Common Functional Gastrointestinal Disorders in Infancy: The Middle East Expert Consensus

  • Indrio, Flavia;Enninger, Axel;Aldekhail, Wajeeh;Al-Ghanem, Ghanem;Al-Hussaini, Abdulrahman;Al-Hussaini, Bakr;Al-Refaee, Fawaz;Al-Said, Khoula;Eid, Bassam;Faysal, Wafaa;Hijazeen, Ruwaida;Isa, Hasan M.A.;Onkarappa, Dinesh;Rawashdeh, Mohammad;Rohani, Pejman;Sokhn, Maroun
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.24 no.4
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    • pp.325-336
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    • 2021
  • The occurrence of functional gastrointestinal disorders (FGIDs) is a formidable challenge for infants, parents, and healthcare professionals. Although data from the Middle East are scarce, experts consider FGIDs a prevalent condition in everyday clinical practice. The new Rome IV criteria revisited the definitions from a clinical perspective to provide a practical and consistent diagnostic protocol for FGIDs. However, the treatment practices for functional disorders vary considerably among Middle Eastern countries, often resulting in mismanagement with unnecessary investigations and treatments. In addition, the role of various treatment modalities, including probiotics such as Lactobacillus reuteri DSM 17938, in FGIDs requires further discussion and evaluation. During a consensus meeting, a locally relevant approach for treating common FGIDs such as infant regurgitation, infant colic, and functional constipation was discussed and approved by regional experts. The participants suggested a simplified treatment plan and protocol for general pediatricians and other primary care physicians managing FGIDs. This easy-to-follow standardized protocol will help streamline the initial management of this complex disorder in the Middle East region and even globally.

A stdudy of Knowledge management system needs and efficient hospital computerized operating

  • Yun, Young Gi;Chung, Young Suk;Park, Koo Rack
    • Journal of the Korea Society of Computer and Information
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    • v.21 no.10
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    • pp.135-142
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    • 2016
  • In this paper, we propose a plan for the introduction of a knowledge-based system proposed by the traditional computing sciences, in order to operate the computer system computerized hospital workers effectively. Hospital computational features of the operating system for this purpose, were made about the working conditions, computational difficulties of the hospital administrator. It is necessary for a knowledge management system for results-effective IT system operational review findings apply to the hospital, where a hospital computer system having features and hospitals computational workers must be resolved on the technical and environmental constraints with It became aware of the need. This study further shows that an effective hospital computer system to derive additional operating a variety of issues to consider for the base and the introduction of a knowledge management system can gradually solve the problem.

A Case of Sarcoidosis with Cavitation (폐 공동을 형성한 유육종증 1예)

  • Lee, Bo Han;Kim, Jin Myong;Kim, Dong Woo;Kim, Jung Hyuk;Bang, Ki Tae;Lee, Kye Young;Jee, Young Koo;Kim, Jae Seuk;Lee, In Sun;Kwon, Mi Seon;Kim, Youn Seup
    • Tuberculosis and Respiratory Diseases
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    • v.59 no.5
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    • pp.546-550
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    • 2005
  • Sarcoidosis is a rare systemic disorder with unknown cause that is characterized pathologically by non-caseating granuloma. The lung and mediastinal lymph nodes are almost always involved, and most patients experience acute or insidious respiratory symptom. Because sarcoidosis is an interstitial lung disorder involving the alveoli and bronchioles, the most common radiological finding is a reticularnodular lesion with lymphatic distribution. However, cavitation is quite rare. Sarcoidosis is also a major cause of hepatic granuloma in Western countries, accounting for 12% to 30% of cases. In most patients, the course of hepatic sarcoidosis is benign. However, chronic intrahepatic cholestasis or portal hypertension may develop in some patients. We report a case of sarcoidosis with cavitation and hepatic involvement.

Rapid Staining Using the Shorr Method for Intraoperative Peritoneal Washing Cytology in Advanced Gastric Cancer: a Pilot Study from a Single Institution

  • Son, Sang-Yong;Choi, Hai-Young;Lee, Yoontaek;Park, Young Suk;Shin, Dong Joon;Oo, Aung Myint;Jung, Do Hyun;Ahn, Sang-Hoon;Park, Do Joong;Lee, Hye Seung;Kim, Hyung-Ho
    • Journal of Gastric Cancer
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    • v.19 no.2
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    • pp.173-182
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    • 2019
  • Purpose: Intraoperative peritoneal washing cytology (PWC) is used to determine treatment strategies for gastric cancer with suspected serosal invasion. However, a standard staining method for intraoperative PWC remains to be established. We evaluated the feasibility of a rapid and simple staining method using Shorr's stain for intraoperative PWC in advanced gastric cancer. Materials and Methods: Between November 2012 and December 2014, 77 patients with clinical T3 or higher gastric cancer were enrolled. The sensitivity, specificity, and concordance between the Shorr staining method and conventional Papanicolaou (Pap) staining with carcinoembryonic antigen (CEA) immunohistochemistry (IHC) were analyzed. Results: Intraoperative PWC was performed laparoscopically in 69 patients (89.6%). The average time of the procedure was 8.3 minutes, and the average amount of aspirated fluids was 83.3 mL. The average time for Shorr staining and pathologic review was 21.0 minutes. Of the 77 patients, 16 (20.7%) had positive cytology and 7 (9.1%) showed atypical findings; sensitivity and specificity were 73.6% and 98.2% for the Shorr method, and 78.9% and 98.2% for the Pap method with CEA IHC, respectively. Concordance of diagnosis between the 2 methods was observed in 90.9% of cases (weighted ${\kappa}$ statistic=0.875) and most disagreements in diagnoses occurred in atypical findings (6/7). In overall survival, there was no significant difference in C-index between the 2 methods (0.459 in Shorr method vs. 0.458 in Pap with CEA IHC method, P=0.987). Conclusions: Shorr staining could be a rapid and reliable method for intraoperative PWC in advanced gastric cancer.

The Effectiveness of Acupuncture for Herpes Zoster: A Systematic Review and Meta-Analysis

  • Seong-Kyeong Choi;Jeong-Hyun Moon;Woo-Seok Jang;Jung-Eun Jang;Si-Hyun Park;Won-Suk Sung;Chan-Yung Jung;Byung-Kwan Seo;Seung-Deok Lee;Kyung-Ho Kim;Eun-Jung Kim
    • Journal of Acupuncture Research
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    • v.40 no.1
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    • pp.16-34
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    • 2023
  • Herpes zoster (HZ) results from the reactivation of a varicella-zoster virus infection and is accompanied by moderate-to-severe pain in most patients. The most common treatment is medication; however, there are still limitations. Acupuncture reportedly has meaningful therapeutic effects and is a possible alternative option in HZ. However, no systematic reviews examining the use of acupuncture and electro-acupuncture (EA) alone have been published; in this study, we therefore aimed to systematically review those techniques. We searched for clinical trials of acupuncture and EA treatment for HZ up to October 2022. Trials that used acupuncture were included. Outcomes were visual analog scale (VAS) and effective rate. Secondary outcomes were time to pain relief, time to pain elimination, incrustation, decrustation, lastly incidence of post-herpetic neuralgia (PHN). In total, 22 randomized controlled trials were included in this research. Compared with conventional medication therapy, acupuncture was associated with a significant improvement in VAS, effective rate, and times to pain relief and elimination. Times to new blister cessation, incrustation, and decrustation (days) were significantly improved. Furthermore, the incidence rate of PHN was lower in acupuncture groups. The results suggest that acupuncture could be a reasonable treatment option for patients with HZ who suffer from pain and accompanying symptoms.

User perception of medical service robots in hospital wards: a cross-sectional study

  • Lee, Jung Hwan;Lee, Jae Meen;Hwang, Jaehyun;Park, Joo Young;Kim, Mijeong;Kim, Dong Hwan;Lee, Jae Il;Nam, Kyoung Hyup;Han, In Ho
    • Journal of Yeungnam Medical Science
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    • v.39 no.2
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    • pp.116-123
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    • 2022
  • Background: Recently, there have been various developments in medical service robots (MSRs). However, few studies have examined the perceptions of those who use it. The purpose of this study is to identify user perceptions of MSRs. Methods: We conducted a survey of 320 patients, doctors, and nurses. The contents of the survey were organized as follows: external appearances, perceptions, expected utilization, possible safety accidents, and awareness of their responsibilities. Statistical analyses were performed using t-test, chi-square test, and analysis of variance. Results: The most preferred appearance was the animal type, with a screen. The overall average score of positive questions was 3.64±0.98 of 5 points and that of negative questions was 3.24±0.99. Thus, the results revealed that the participants had positive perceptions of MSR. The overall average of all expected utilization was 4.05±0.84. The most expected utilization was to guide hospital facilities. The most worrisome accident was exposure to personal information. Moreover, participants thought that the overall responsibility of the robot user (hospital) was greater than that of the robot manufacturer in the case of safety accidents. Conclusion: The perceptions of MSRs used in hospital wards were positive, and the overall expected utilization was high. It is necessary to recognize safety accidents for such robots, and sufficient attention is required when developing and manufacturing robots.

Association between the simultaneous decrease in the levels of soluble vascular cell adhesion molecule-1 and S100 protein and good neurological outcomes in cardiac arrest survivors

  • Kim, Min-Jung;Kim, Taegyun;Suh, Gil Joon;Kwon, Woon Yong;Kim, Kyung Su;Jung, Yoon Sun;Ko, Jung-In;Shin, So Mi;Lee, A Reum
    • Clinical and Experimental Emergency Medicine
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    • v.5 no.4
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    • pp.211-218
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    • 2018
  • Objective This study aimed to determine whether simultaneous decreases in the serum levels of cell adhesion molecules (intracellular cell adhesion molecule-1 [ICAM-1], vascular cell adhesion molecule-1 [VCAM-1], and E-selectin) and S100 proteins within the first 24 hours after the return of spontaneous circulation were associated with good neurological outcomes in cardiac arrest survivors. Methods This retrospective observational study was based on prospectively collected data from a single emergency intensive care unit (ICU). Twenty-nine out-of-hospital cardiac arrest survivors who were admitted to the ICU for post-resuscitation care were enrolled. Blood samples were collected at 0 and 24 hours after ICU admission. According to the 6-month cerebral performance category (CPC) scale, the patients were divided into good (CPC 1 and 2, n=12) and poor (CPC 3 to 5, n=17) outcome groups. Results No difference was observed between the two groups in terms of the serum levels of ICAM-1, VCAM-1, E-selectin, and S100 at 0 and 24 hours. A simultaneous decrease in the serum levels of VCAM-1 and S100 as well as E-selectin and S100 was associated with good neurological outcomes. When other variables were adjusted, a simultaneous decrease in the serum levels of VCAM-1 and S100 was independently associated with good neurological outcomes (odds ratio, 9.285; 95% confidence interval, 1.073 to 80.318; P=0.043). Conclusion A simultaneous decrease in the serum levels of soluble VCAM-1 and S100 within the first 24 hours after the return of spontaneous circulation was associated with a good neurological outcome in out-of-hospital cardiac arrest survivors.