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The Effects of Radix aconiti on the Contraction of Rat's Spinal Cord Injury (부자(附子)의 경구투여(經口投與)가 RAT의 척수손상(脊髓損傷)에 미치는 영향(影響) 및 비교(比較))

  • Lee Geon-Mok;Kim Kyung-Sik;Lee Kang-Chang
    • Journal of Acupuncture Research
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    • v.15 no.2
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    • pp.105-116
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    • 1998
  • Purpose In this study, We observed the recovery process in the ability to move in the hind limbs of the rats whose spinal cord injuries were treated by Radix acouniti(RA). The purpose of this study is to see the effects of Radix acouniti(RA) water extract on the contraction of rat's spinal cord injury. Procedure First, the rats were subjected to hemisectional spinal cord injuries by a scalpel blade. Those rats, then, were divided into three groups: Sham operated rats group and the experimental group, which received the Radix acouniti(RA) water extract, and the control group, which had no treatment. Their recovery in the ability to walk was observed by the Open Field Test (OFT) for 14 days after the injuries. Method The OFT was applied at four points: the hip, knee, ankle joint, and the tail. Each joint was given a movement rating of from 0 to 3, depending on the amount of movement. A movement rating of 0 designates no movement, a 1 designates slight movement, a 2 designates increased movement, and a 3 designates active movement. Slight movement is defined as a joint displaying less than or equal to 30% of that joint range, increased movement is displaying less than or equal to 60% of that joint's range, and active movement is greater than or equal to 90% of that joint's range. Tail movement is also graded on a scale of 0 to 3. A rating of 0 indicates that the tail is down 100% of the time, one of 1 indicates that the tail is down more than 10%, one of 2 shows that the tail is down less than 50% but more than 10% of the time, and one of 3 shows that the tail is down less than 10% of the time. All four ratings were added together and then averaged to arrive at a single score. Results The sham group which did not go through spinal cord injuries showed near normal results on all 3 joints and tail from right after the operation, which one would expect. The RA oral application group showed more effective recovery of movememt function than the control group around 4 days after the spinal cord injuries. However, after 14 days, both groups displayed almost the same degree of movement recovery. The results of this study are summarized as follows: 1. After 14days the spinal cord injuries, movement was recovered in sham operated group, control group, and experimented group in the hip, the knee, the tail and then the ankle of rats, in that order. 2. Around 7 days after the spinal cord injuries, the experimental group proved the effectiveness of the therapy in terms of movement recovery. 3. The level of ALT, ALP, AST in RA treated group was slightly increased. 4. The level of BUN and creatinine in RA treated group was slightly increased. The above results indicate that RA therapy at an early stage can bring about better movement recovery in patients with spinal cord injuries from traffic accidents or industrial disasters. But there is apparent side effect of RA on clinical, therefore the study on this should be continued.

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Quality Characteristics of Backsulgi Added with Job′tears and Brown Rice (율무쌀과 현미를 첨가한 백설기의 관능적 품질 특성)

  • 정현숙
    • Journal of the East Asian Society of Dietary Life
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    • v.6 no.2
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    • pp.177-186
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    • 1996
  • This study attempted to examine the sensory quality, the degree of gelatization, color, texture and moisture content of Backsulgi added with Jobs'tears and Brown rice. The results were as follows: In sensory quality Backsulgi added with 10% Jobs'tears and Brown rice showed the most favorable sensory evaluation. In view of color, flavor, afterswallowing and overall quality, 10% Backsulgi was preferable than those of other Backsulgi added with Jobs'tears and Brown rice. The moisture contents was about 36-40%. There are not changed after 24hr and 48hr. L-value on the control group was high, 90.08. and Al, A2, A3 and A4 group were 80.65, 71.63, 68.66 and 61.50 respectively. L-value on the Backsulgi added with Jobs'tears was decreased as the amount of Jobs'tears. The gelatinization of Backsulgi added with Jobs'tears and Brown rice was Increased as the amount of Jobs'tears and Brown rice.

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A Study of the Relationship Between Perceived Social Support and Quality of Life of Cancer Patients receiving Gene therapy (유전자 치료를 받는 암 환자가 지각하는 사회적 지지와 삶의 질과의 관계 연구)

  • Chang, Mi-Kyung;Kim, Kyung-Hee;Chung, Yeon-Kang
    • Research in Community and Public Health Nursing
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    • v.8 no.1
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    • pp.74-88
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    • 1997
  • The purpose of this study was to identify the relationship between perceived social support and the quality of life of cancer patients receiving gene therapy. The subjects for this study were 50 cancer patients receiving gene therapy at two general hospital in Seoul. The data were collected during the period from October 14, 1996 to November 11, 1996. The perceived social support was measured by the family support scale made by Hyun Sook Kang, by the medical support of life scale developed by Ok Soo Kim. The quality of life scale developed by Bang-Whal-Ran was used, among the questionnaire, physical factors was developed by U.S.A National Conference on Cancer Nursing. The data was analysed by the SAS statistical program. Percentile, means and standard deviations, t -test, ANOVA, Scheffe test, Pearson correlation were utilized for analysis. The results of this study were as follows. 1. The mean score of the perceived social support of the subjects was 83.66, the item score was 3.8. 1) The mean score of the perceived family support of the subjects was 44.96, the item mean score was 4.5. 2) The mean score of the perceived professional medical support of the subjects was 38.70, the item mean score was 3.2. 2. The mean score of quality of life of the subjects was 120.38, the item mean score was 3.17. For each factor in quality of life scale, the mean score was follows: for attitude toward life, 3.95, for familial relationship and financial status, 3.53, for social activity 3.24, for emotional status, 3.08, for healthy perceptive, 2.90, for physical symptom, 2.80. 3. The result of the analysis of the relationship between perceived social support and quality of life showed a positive correlation(r=.4853, p=.0004). Therefore, the higher the perceived social support of the patients, the higher the quality of life. 1) The result of the analysis of the relationship between perceived family support and quality of life showed significant correlation(r=. 3566, p=.0110). Therefore the higher the perceived family support of the patients, the higher the quality of life. 2) The result of the analysis of the relationship between perceived professional medical support and quality of life showed significant correlation (r=.4477, p=.0011). Therefore, the higher the perceived professional medical support of the patients the higher the quality of life. 4. There was a significant difference in perceived social support according to sex(F=2.1437, p= .0371), others coping non-family (F=2.4863, p=.0164) and duration of treatment (F=4.16, p=.0218). 5. There was a significant differance in quality of life according to sex(F=2.6932, p=.0097), degree of education(F=2.3610, p=.0223), others coping non-family(F=2.0502, p=.0458). In conclusion, this study revealed that social support is an important factor that associated with the quality of life in cancer patients receiving gene therapy.

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Properties of Chemically Activated MSWI(Municipal Solid Waste Incinerator) Mortar (도시 폐기물 소각재를 이용한 화학적 활성화 모르타르의 특성)

  • Jo, Byung-Wan;Kim, Kwang-Il;Park, Jong-Chil;Park, Seung-Kook
    • Journal of the Korea Concrete Institute
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    • v.18 no.5 s.95
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    • pp.589-594
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    • 2006
  • The recycling of industrial wastes in the concrete manufacturing is of increasing interest worldwide, due to the high environmental impact of the cement and concrete industries and to the rising demand of infrastructures, both in industrialized and developing countries. The production of municipal wastes in the South Korea is estimated at about 49,902 ton per day and only 14.5% of these are incinerated and principally disposed of in landfill. These quantities will increase considerably with the growth of municipal waste production, the progressive closing of landfill, so the disposal of municipal solid waste incinerator(MSWI) ashes has become a continuous and significant issue facing society, both environmentally and economically. MSWI ash is the residue from waste combustion processes at temperature between $850^{\circ}C\;and\;1,000^{\circ}C$. And the main components of MSWI ash are $SiO_2,\;CaO\;and\;Al_2O_3$. The aim of this study is to find a way to useful application of MSWI ash(after treatment) as a structural material and to investigates the hydraulic activity, compressive strength development composition variation of such alkali-activated MSWI ashes concrete. And it was found that early cement hydration, followed by the breakdown and dissolving of the MSWI-ashes, enhanced the formation of calcium silicate hydrates(C-S-H). The XRD and SEM-EDS results indicate that, both the hydration degree and strength development are closely connected with a curing condition and a alkali-activator. Compressive strengths with values in the 40.5 MPa were obtained after curing the activated MSWI ashes with NaOH+water glass at $90^{\circ}C$.

Predicting Construction Project Cost using Sensitivity Analysis in Stochastic Project Scheduling Simulation (SPSS) (확률 통계적 일정 시뮬레이선 - 민감도 분석을 이용한 최종 공사비 예측)

  • Lee Dong-Eun;Park Chan-Sik
    • Korean Journal of Construction Engineering and Management
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    • v.6 no.4 s.26
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    • pp.80-90
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    • 2005
  • Activity durations retain probabilistic and stochastic natures due to diverse factors causing the delay or acceleration of activity completion. These natures make the final project duration to be a random variable. These factors are the major source of financial risk. Extending the Stochastic Project Scheduling Simulation system (SPSS) developed in previous research; this research presents a method to estimate how the final project duration behaves when activity durations change randomly. The final project cost is estimated by considering the fluctuation of indirect cost, which occurs due to the delay or acceleration of activity completion, along with direct cost assigned to an activity. The final project cost is estimated by considering how indirect cost behaves when activity duration change. The method quantifies the amount of contingency to cover the expected delay of project delivery. It is based on the quantitative analysis to obtain the descriptive statistics from the simulation outputs (final project durations). Existing deterministic scheduling method apply an arbitrary figures to the amount of delay contingency with uncertainty. However, the stochastic method developed in this research allows computing the amount of delay contingency with certainty and certain degree of confidence. An example project is used to illustrate the quantitative analysis method using simulation. When the statistical location and shape of probability distribution functions defining activity durations change, how the final project duration and cost behave are ascertained using automated sensitivity analysis method

Effects of School-Based Social Skills Training Program on Alexithymic Tendency: Preliminary Study (사회성 증진 프로그램이 감정표현불능증에 미치는 효과에 대한 예비연구)

  • Kim, Min-Soo;Shin, Jung-Uk;Lee, Young-Ryeol;Lee, Yeon-Woo;Jung, Kyung-Ae;Jung, Dool-Nam;Park, Mi-Ri;Song, Gang-Sik;Seo, Sang Soo
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.27 no.3
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    • pp.216-225
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    • 2016
  • Objectives: The purposes of this study are to evaluate the effect of a school-based social skills training program on the emotional regulation of children and adolescents and to assess the plan for effective school-based mental health services. Methods: The Child and Adolescent Mental health promotion team of Bugok National Hospital conducted school-based social skills training (N=90, 7 sessions) for elementary and middle school students. Evaluations were conducted before and after the application of the program using a prosocial behavior questionnaire, a cohesiveness questionnaire, the Korean version of the 20-item Toronto Alexithymia Scale, a self-esteem scale, and the Novaco anger scale, in order to identify any changes. Results: The social skills training program increased the prosocial behavior and cohesiveness of the children and adolescents and decreased their alexithymic tendency and degree of anger, but did not significantly change their self-esteem. Conclusion: The social skills training program positively influences the emotional and behavioral levels of children and adolescents. The emotional regulation program based on a social skills training program is expected to have positive results in school-based mental health services. Future investigations are needed to validate the long term effects of this program.

Influence of Positional Changes of Arms and Legs to Electrocardiogram

  • Song, Joo-Eun;Song, Min-Ju;Kim, Ye-Sul;Yang, Ha-Nuel;Lee, Ye-Jin;Jung, Dongju
    • Biomedical Science Letters
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    • v.24 no.1
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    • pp.43-49
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    • 2018
  • Electrocardiogram (ECG) is a widely used method to diagnose electrical activity of heart. Although it is a reliable and easy method, ECG could be interfered by electrical signals. One of the interfering signals is electromyogram (EMG) that is caused by muscle contraction in any parts of the body except heart. To avoid the EMG noise, an examinee is advised to be relaxed on supine position while measuring ECG. Sometimes, patients who can't put their arms and legs down on bed due to some reasons such as cast on arms or legs necessarily have the EMG noise. But detailed information about how much of the noise could be induced by positional change of arms and legs has not been reported. Here we examined the noise by analyzing ECG data from 14 candidates, 7 males and 7 females. The ECG data was obtained using the standard 12 lead ECG. EMG noise was induced by raising arms and legs at $90^{\circ}$, $60^{\circ}$ or $30^{\circ}$. Because arms are located close to the heart, noise by the raised arms was analyzed toward left or right arm separately. All of the examinees showed similar pattern of the EMG noise. EMG noise by positional change of left or right arm was clearly monitored in different limb leads. Change of leg positions induced the noise that was monitored in aVF of augmented leads and II and III of limb leads. There was a difference in degree of the noise between male and female examinees. In addition to the EMG noise, decrease of PR interval was monitored in particular positional changes, which was prominent in male examinees. These results will enlarge fundamental understanding about EMG noise in ECG.

The Effect of Music Therapy on Cognitive Function, Behavior and Emotion of Dementia Elderly (음악요법이 치매노인의 인지기능, 행동, 정서에 미치는 효과)

  • Sim, Hyang-Mi;Chung, Seung-Hee
    • Korean Journal of Adult Nursing
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    • v.13 no.4
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    • pp.591-600
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    • 2001
  • Purpose: This study was to observe the effects of music therapy on the cognitive function, behavior, and emotions of elderly dementia patients, and to seek musical mediation for them. This study was conducted with patients in the Dementia Sanitarium in C City from March 13 to April 17. Method: The design of research was a nonequivalent control group non-synchronized design and the subjects were 25 patients-15 of whom were in the experimental group with 10 in the control group. The music therapy consisted of favorite music listening in the morning, favorite music group singing activity after lunch, and relaxing music listening after dinner. The schedule was followed 6 days a week for 2 weeks for a total of thirty-six session. The effect of music therapy was measured by MMSE-K and the behavior and emotion measuring equipment which had been derived by the researcher. The verification of the effects is that the score of cognitive function, behavior, and emotions of the experimental and the control group which were measured after the therapy had been applied was analyzed by descriptive statistics and t - test using SPSS WIN program. Result: 1) The degree of cognitive function of the experimental group which was received the music therapy is $11.53{\pm}5.37$ which is a little higher than the control group which is $11.20{\pm}6.32$, but it is not significant statistically (t= .14, p= .887). The first hypothesis which had assumed the recepients would have had a higher cognitive function level than the other was rejected. 2) Behavior score of the experimental group that received the music therapy is $68.90{\pm}7.86$ which is higher than the control group which is $66.40{\pm}11.13$, but it is not significant statistically(t= .61, p= .548). The second hypothesis which had assumed the recepients would have had a higher behavior level than the other was rejected. 3) Emotions score of the experimental group that received the music therapy is $42.13{\pm}5.04$ which is higher than the control group which is $35.20{\pm}6.12$, and it is significant statistically(t=3..09, p= .009). The third hypothesis which assumed the recepients would have had a higher emotion level was supported. Conclusion: music therapy which is composed of listening to music and group singing activity is an effective strategy for improvement of the emotions of the dementia elderly. But, the effect of music therapy on the cognitive function and behavior of elderly dementia patients is not significant statistically.

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Studies on Ion-Selective Crown Ether Dyes (이온선택성 크라운 에테르 염료에 관한 연구)

  • Sam-Woo Kang;Chong-Min Park;Won-Fae Koo;Keun-Jae Kim;Soo-Min Lee;Choo-Hwan Chang
    • Journal of the Korean Chemical Society
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    • v.32 no.5
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    • pp.443-451
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    • 1988
  • New crown ether dye-Ⅰ and dye-Ⅱ having an azo group(-N=N-) were synthesized from monobenzo-15-crown-5 and dibenzo-18-crown-6. These dyes showed ${\lambda}_{max}$ of 377 and 383nm respectively. The complexes of alkali metal ions ($Na^+$, $K^+$, $Cs^+$) with dye ligands showed band shift (390~400nm) and intensity increased. For a given anion, the extraction constants are in the order of $K^+$ < $Cs^+$ < $Na^+$ for dye-Ⅰ and $Cs^+$ < $Na^+$ < $K^+$ for dye-Ⅱ. These results show that the selectivity of crown ethers toward the alkali metal ions is dependant on the charge density of cation and the size of crown ether cavity. For a given cation, the order of the extraction constant is $Cl^-$ < $Br^-$ < $I^-$ < picrate. This order coincides with the degree of anion solvation effect.

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Occlusion Effect of Dentinal Tubules of the Desensitizing Dentifrices Marketed in Korea (국내 시판중인 지각과민 완화 치약의 상아세관 폐쇄효과)

  • Lee, Su-Young
    • Journal of dental hygiene science
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    • v.11 no.5
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    • pp.431-436
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    • 2011
  • The aim of this study was to compare the effects of the short-term use of the desensitizing dentifrices marketed in Korea in vitro. Fifty human dentine specimens were wet ground with silicone carbide paper and etched with 6% citric acid for 90 seconds to allow complete opening of the dentinal tubule. Ten specimens from each group were brushed for 50 and 150 strokes with a V8 Cross Brushing Machine(Sabri Co., U. S. A). All the specimens were evaluated by SEM(${\times}3000$). The degree of occlusion of the dentinal tubules was quantified using an image analyzer. The results were analyzed by one-way ANOVA and Tukey's multiple comparisons using Window SPSS. The dentifrices containing nano-carbonate apatite, potassium nitrate and hydroxyapatite showed significantly higher occlusion effects than the other dentifrices after toothbrushing for 50 strokes(p<0.05). The Sensodyne freshmint$^{(R)}$dentifrice showed 34% fewer open tubular areas compared with the Sensodyne original$^{(R)}$dentifrice for 50 strokes. According to the short-term use of desensitizing dentifrices, the dentifrices containing nano-carbonate apatite, potassium nitrate and hydroxyapatite were most effective in occluding the dentinal tubules.