• Asian Pacific Journal of Cancer Prevention
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• v.14 no.6
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• pp.3521-3526
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• 2013

Objective: The current study explored the expression of KAI1/CD82 and MRP1/CD9 and its significance in laryngeal squamous cell carcinoma (LSCC). Methods: The expression levels of KAI1/CD82 and MRP1/CD9 in 100 LSCC tissue specimens, as well as in 30 para-LSCC non-carcinomatous tissue specimens randomly taken from the patients, were assessed using the quantitative polymerase chain reaction (Q-PCR) and immunohistochemistry and correlations with pathological parameters of LSCC and their influence on survival function were analyzed. Results: KAI1/CD82 and MRP1/CD9 showed basically consistent changes in both mRNA and protein expression. Their expression in the 30 LSCC specimens was significantly lower compared with that in the corresponding non-carcinous tissues (P < 0.01 or 0.05), notably correlating with TNM stage, differentiation degree, clinical stage, and lymphatic metastasis (P < 0.01 or 0.05), but not gender, age, and LSCC growth sites (P > 0.05). The median survival of patients with positive KAI1/CD82 and MRP1/CD9 protein expression was longer than that of patients with negative protein expression (P < 0.01 or 0.05). KAI1/CD82 protein expression negatively correlated with MRP1/CD9 protein expression in LSCC (${\chi}^2$= 31.25, P < 0.01). Conclusion: KAI1/CD82 and MRP1/CD9 may jointly participate in the development of LSCC. They may serve as the markers for judging the infiltration, metastasis, and prognosis of LSCC.

• Korean Journal of Environment and Ecology
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• v.28 no.5
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• pp.566-573
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• 2014

Decay rate and nutrient dynamics during leaf litter decomposition of deciduous broad leaf Quercus mongolica and evergreen needle leaf Pinus densiflora were investigated for 69 months from December 2005 to September 2011 in Mt. Worak National Park as a part of National Long-Term Ecological Research Program in Korea. Percent remaining weight of Q. mongolica and P. densiflora leaf litter after 69 months elapsed was $35.4{\pm}2.3%$ and $16.1{\pm}1.3%$, respectively. Decomposition of P. densiflora leaf litter was significantly faster than that of Q. mongolica leaf litter. Decay constant (k) of Q. mongolica and P. densiflora leaf litter after 69 months elapsed was 5.97 and 10.50, respectively. Initial C/N and C/P ratio of Q. mongolica leaf litter was 43.1 and 543.9 respectively. After 69 months elapsed, C/N and C/P ratio of decomposing Q. mongolica leaf litter decreased to 8.7 and 141.2, respectively. Initial C/N and C/P ratio of P. densiflora leaf litter was 151.2 and 391.4, respectively. After 69 months elapsed, C/N and C/P ratio of decomposing P. densiflora leaf litter decreased to 22.9. and 136.5. respectively. Initial concentration of N, P, K, Ca and Mg in leaf litter was 9.30, 0.23, 2.36, 3.14, 1.11 mg/g in Q. mongolica, and 3.02, 0.09, 1.00, 3.84, 0.62 mg/g in P. densiflora, respectively. Initial concentration of N and P in Q. mongolica leaf litter was significantly higher than those in P. densiflora. After 69 months elapsed, remaining N, P, K, Ca and Mg in decomposing leaf litter were 73.8, 60.9, 17.2, 20.3, 35.1 % in Q. mongolica, and 69.5, 75.3, 12.3, 10.9, 10.8 % in P. densiflora, respectively.

• Parasites, Hosts and Diseases
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• v.48 no.1
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• pp.9-13
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• 2010

Pentatrichomonas hominis is considered a commensal protozoan in the large intestine of a number of mammalian hosts, such as cats, dogs, and non-human primates. The resulting infections, which can induce diarrhea, have been attributed to opportunistic overgrowth of P. hominis. This study was performed to confirm the P. hominis infection and its molecular characterization from the feces of puppies with diarrhea. Fecal samples were obtained from 14 German shepherd puppies with diarrhea over 1 week (7 females and 7 males, 2-9 months of age) residing on a dog farm in August 2007. Species-specific PCR assay identified P. hominis 18S rRNA genes in 3 of the 14 puppies (1 female and 2 males; 1 aged 2 months and 2 aged 9 months). This phylogenetic analysis established that P. hominis belonged to the 1st clade, which is comprised of Bos taurus and Felines.

• Korean Journal of Environment and Ecology
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• v.11 no.4
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• pp.493-505
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• 1998

To study vegetation structure and distance between trees of Pinus densiflora forest in Chayang-chon area, Soraksan National Park, thirty-nine plots(10m$\times$10m) were established. They were classified into two communities by TWINSPAN and DCA technique. In the Community I, P. densiflora(DBH 35~75cm, height 9~16m, age 60~80) dominated in canopy and were predicted to be changed by deciduous broad-leaved trees also. In the Community II, P. densiflora(DBH 9~26.5cm, height 9~16m, age 30~50m) dominated in canopy. It seemed that the community II would maintain P. densiflora community for a long time since P. densiflora dominated in both canopy and understory. Shonnon's diversity index was higher in the community II(1.4247) than in the community I(1.2978). The distantes between canopy trees were 4.92$\pm $2.14m in the community I and 2.41$\pm $0.97m in the community II. The regression between DBH in canpy and ecological distance was Y(Distance) = 0.06355$\times $(DBH)+1.51613.

• Korean Journal of Agricultural Science
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• v.4 no.2
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• pp.229-238
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• 1977

Sumithion and EPN residues on grapes, EPN and Diazinon on chinese cabbage, Parathion on peaches, Dimethoate on tomatoes, and EPN and Malathion on cucumber were analyzed in terms of 0, 3, 7, 14, 21 and 30 days after last application for the pesticides safty use. From the disappearance rate for various organo-phosphate insecticides on vegetables and fruit crops, following results are obtained. 1. On Chinese cabbage, Diazinon residues were 0.25~0.38p.p.m three weeks after one application, and EPN were 1.39~2.69p.p.m seven days after one application and 0.96~2.34p.p.m two weeks after twice application. 2. EPN residues on grapes were 1.09~1.80p.p.m seven days after one application and Sumithion were 0.17~0.53p.p.m fourteen days after one application. 3. On peaches, Parathion residues were 0.40~0.61p.p.m two weeks after last application. 4. Dimethoate residues on tomatoes were 0.141p.p.m seven days after four times application. 5. On cucumber, EPN residues were 2.11~2.14p.p.m three days after twice application, and Malathion were 0.46p.p.m 3 day after four times application but 0.062~0.025p.p.m three days after last application. 6. Rate of degradation of organo-phosphate chemicals is inversely related to half-life of its. 7. Minimum intervals between last treatment and harvest to prevent unsafty residues are as follows. 7 days for EPN with one application and 14 days with twice application on chinese cabbage, 3 days on cucumber and 7 days on grape, 14 days for parathion, 7 days for dimethoate on tomatoes, 0 to 3 days for Malathion on cucumber, 21 days for Sumithion on grape, 21 days on chinese cabbage for Diazinon.

• Korean Journal of Agricultural Science
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• v.13 no.1
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• pp.147-150
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• 1986

Fourteen Korean native goats were examined to obtain physiological basic data on electrolyte contents in serum and rumen juice. In addition, pH and total number of ciliates in the rumen juice were investigated. The results obtained were as follows: 1. The serum $Na^+$, $K^+$ and $Cl^-$ levels were $151.9{\pm}4.5(145-160)mEq/l$, $8.1{\pm}1.5(5.3-10.0)mEq/l$ and $104.6{\pm}4.6(99-112)mEq/l$, respectively. 2. $Na^+$, $K^+$ and $Cl^-$ values in the rumen juice were $104.7{\pm}15.8(70-131)mEq/l$, $38.2{\pm}9.9(18-58)mEq/l$ and $14.1{\pm}4.3(8-24)mEq/l$, respectively. 3. The pH of the rumen juice was $5.6{\pm}0.3(5.3-6.5)$ and the total number of ciliates were $2.59{\pm}0.8(0.64-3.29){\times}10^6/ml$.

• Journal of Korean Physical Therapy Science
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• v.9 no.1
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• pp.129-134
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• 2002

The aim of this study is to present the basic reference data of age and specipic gait parameters for Hemiplegia Patients. The basic gait parameters were extracted from 10 Adult Hemiplegia Patients, 5 left Hemiplegia Patients and 5 right Hemiplegia Patients, 50 to 60 years of age using VICON 512 Motion Analyzer. The results were as follows; 1) The mean Cadence of the left to the right hemiplegia were $75.81{\pm}28.10\;steps/min$, to $68.47{\pm}9.93\;steps/min$. 2) The mean Walking Speed of the left to the right hemiplegia were $0.45{\pm}0.28\;m/s$, to $0.44{\pm}0.14\;m/s$. 3) The mean Stride Length of the left to the right hemiplegia were $0.66{\pm}0.31\;m$, to $0.76{\pm}0.17m$. 4) The mean. maximal angles of joint on the pelvic tilt for different right or left hemiplegia were $8.59{\pm}5.13^{\circ}$, to $11.85{\pm}5.23^{\circ}$.(p>0.05) 5) The mean maximal angles of joint on the hip flexion motion for different right or left hemiplegia were $23.98{\pm}8.45^{\circ}$, to $25.81{\pm}5.39^{\circ}$.(p>0.05) 6) The mean maximal angles of joint on the knee flexion motion for different right or left hemiplegia were $29.52{\pm}10.24^{\circ}$, to $28.38{\pm}14.48^{\circ}$.(p>0.05) 7) The mean maximal angles of joint on the ankle dorsiflexion motion for different right or left hemiplegia were $14.68{\pm}5.03^{\circ}$, to $9.90{\pm}7.26^{\circ}$.(p>0.05) 8) The mean maximal angles of joint on the ankle plantarflexion motion for different right or left hemiplegia were $2.10{\pm}5.17^{\circ}$, to $8.63{\pm}5.81^{\circ}$.(p>0.05)

• Tuberculosis and Respiratory Diseases
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• v.87 no.2
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• pp.165-175
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• 2024

Background: The prevalence of small airway dysfunction (SAD) in patients with chronic obstructive pulmonary disease (COPD) across different ethnicities is poorly understood. This study aimed to estimate the prevalence of SAD in stable COPD patients. Methods: We conducted a cross-sectional study of 196 consecutive stable COPD patients. We measured pre- and post-bronchodilator (BD) lung function and respiratory impedance. The severity of COPD and lung function abnormalities was graded in accordance with the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines. SAD was defined as either difference in whole-breath resistance at 5 and 19 Hz > upper limit of normal or respiratory system reactance at 5 Hz < lower limit of normal. Results: The cohort consisted of 95.9% men, with an average age of 66.3 years. The mean forced expiratory volume 1 second (FEV₁) % predicted was 56.4%. The median COPD assessment test (CAT) scores were 14. The prevalence of post-BD SAD across the GOLD grades 1 to 4 was 14.3%, 51.1%, 91%, and 100%, respectively. The post-BD SAD and expiratory flow limitation at tidal breath (EFL_T) were present in 62.8% (95% confidence interval [CI], 56.1 to 69.9) and 28.1% (95% CI, 21.9 to 34.2), respectively. COPD patients with SAD had higher CAT scores (15.5 vs. 12.8, p<0.01); poor lung function (FEV₁% predicted 46.6% vs. 72.8%, p<0.01); lower diffusion capacity for CO (4.8 mmol/min/kPa vs. 5.6 mmol/min/kPa, p<0.01); hyperinflation (ratio of residual volume to total lung capacity % predicted: 159.7% vs. 129%, p<0.01), and shorter 6-minute walk distance (367.5 m vs. 390 m, p=0.02). Conclusion: SAD is present across all severities of COPD. The prevalence of SAD increases with disease severity. SAD is associated with poor lung function and higher symptom burden. Severe SAD is indicated by the presence of EFL_T.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.336-344
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• 2021

The purpose of this study was to identify the self-awareness of smartphone dependence among undergraduate students and their response to the same. The data was drawn from a survey on smartphone overdependence conducted by the Ministry of Science and information and communications technology (ICT) and the National Information Society Agency in 2017. The responses of 1,735 undergraduate students were analyzed by frequency, percentage, mean, standard deviation, minimum-maximum value, ��2-test, independent t-test, Pearson's correlation coefficient, and stepwise multiple regression analysis. The results indicated that 22.3% of participants were at risk of smartphone dependence, and 63.6% of them were unaware of their dependence on smartphones. The perception of smartphone dependence was significantly associated with a higher risk of smartphone dependence (��=.35, p=.000) and the increasing use of applications such as games (��=.19, p=.000), television/video (��=.11, p=.000), and learning (��=.11, p=.000). Of the participants with dependence awareness, only a few knew about the existence of centers to prevent smartphone and internet dependence. Moreover, they rarely utilized these centers. However, the participants felt the need for more counseling agencies (26.8%), programs for dealing with oneself (23.2%), information about smartphone dependence (14.9%), and help to overcome dependence (10.9%). These findings show the need to establish public services so that students can easily access correct information on smartphone dependence and address this problem.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.1101-1106
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• 2013

Background: Osteosarcoma is the most common primary bone tumor in childhood and adolescence. Carboplatin, a platinum-derived agent, is used as neoadjuvant chemotherapy for pediatric osteosarcoma because of its anti-tumor activity and had low toxicity as compared to cisplatin. Objective: To determine demographic data, prognostic factors and outcome of childhood osteosarcoma treated with a carboplatin-based chemotherapeutic protocol at Chiang Mai University. Method: A retrospective analysis was conducted on 34 osteosarcoma patients aged less than 18 years and treated between 2003 and 2011. Results: Overall limb-salvage and amputation rates were 23.5% and 70.6%, respectively. With the mean follow-up time of 29.5 months (1.5-108.9), the Kaplan-Meier analysis for 3-year disease-free survival (DFS) and 3-year overall survival (OS) were $20.2{\pm}7.7%$ and $47.1{\pm}9.5%$ respectively. Patients who had initial pulmonary metastasis were at significantly greater risk for developing recurrence (p=0.02, OR=7; 1.2-40.1) and had a tendency to have lower 3-year OS compared to those without initial pulmonary metastasis ($28.1{\pm}13%$, $63.1{\pm}12.3%$, respectively, p=0.202). On univariate analysis, age at diagnosis >14 years and patients who were declined surgery were significantly associated with lower 3-year OS (p=0.008 and <0.05, respectively). However, age at diagnosis, sex, tumor size and histological subtypes were not found to significantly affect recurrence or survival. Conclusions: In our study, the survival rate was far lower than those reported from developed countries. These might indicate the ineffectiveness of carboplatin in combination with doxorubicin as frontline treatment of pediatric osteosarcoma, especially in those with initial pulmonary metastasis. Refinement in risk and treatment stratification and dose intensification for pediatric osteosarcoma constitutes a future challenge to improve outcomes, especially in metastatic patients who may need a more intensive regimen.