• 한국식품과학회지
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• 제29권2호
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• pp.198-203
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• 1997

마쇄한 감 puree에 2종류의 상업적 다른 탄수화물 분해효소인 Viscozyme과 Celluclast를 처리하여 얻은 감쥬스의 추출수율, 점도, 색, 적정산도, 당에 미치는 영향을 조사하였다. Arabinase, cellulase, xylanase, hemicellulase와 ${\beta}-glucanase$의 효소활성을 가진 Viscozyme으로 $50^{\circ}C$에서 10분간 가수분해할 때 추출수율, L값, 환원당은 현저히 증가하였고 점도는 감소하였다. 감쥬스의 추출수율은 Viscozyme으로 처리시 42.8%에서 80%로 증가하는 반면 Celluclast는 73.3%로 증가하였다. 한편 관능적 특성중 감맛과 감내, 주홍색과 주황색은 Viscozyme으로 60분간 가수분해한 쥬스에서 크게 향상되었다.

• Preventive Nutrition and Food Science
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• 제13권3호
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• pp.212-218
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• 2008

We extracted red ginseng with various alcohol concentrations and evaluated total carbohydrate, uronic acid, polyphenols compounds and ginsenoside contents, and yields of alcohol extract. The water extraction (0% alcohol extraction) showed a high level of total carbohydrate content. 10% and 20% alcohol extraction showed the highest uronic acid contents (7,978.8 and $7,872.7\;{\mu}g/mL$ of extract, respectively). The efficiency order of the red ginseng extract (RGE) preparations in liberating polyphenols was: $0{\sim}50%$ alcohol${\geq}\;60%$ alcohol> $70{\sim}90%$ alcohol. Solid contents in RGE were decreased with increased alcohol concentration; the same tendency as with the results of total carbohydrate content. Total ginsenoside contents in $20{\sim}50%$ alcohol extracts showed similar levels ($442,962.9{\sim}47,930.8\;{\mu}g/mL$ of extract). Water extraction showed the lowest ginsenoside content ($14,509.4\;{\mu}g/mL$ of extract). The ginsenoside contents at above 60% alcohol were decreased with increased alcohol concentration. Generally, ginsenoside (Rg2, Rg1, Rf, Re, Rd, Rb2, Rc and Rb1) contents were increased with increased alcohol concentrations. However, Rg3 content was decreased with increases in alcohol concentration.

• 생약학회지
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• 제47권3호
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• pp.197-203
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• 2016

Decursin is a major component of the root of Angelica gigas(Umbelliferae), which has been traditionally used in Korea as a tonic and to treat anemia, hemiplegia, and women's diseases. The objective of this study is to identify the anti-cancer mechanism induced by decursin on apoptosis of human leukemia and lymphoma cells. Cytotoxicity of decursin on U937, HL-60, MOLT-4, THP-1 cells showed the significant effects. First of all, $IC_{50}$ of decursin on four cell lines was 27.1, 32.4, 17.4, $15.1{\mu}M$, respectively. So $IC_{50}$ in THP-1 cells was the smallest among 4 cell lines treated with decursin($15.1{\mu}M$). In order to understand the apoptosis-mechanism by decursin, we examined the gene expression of bcl-2(anti-apoptotic), bax(pro-apoptotic) and p53(tumor suppressor)after treating the THP-1 cells with decursin(10, 50 and $100{\mu}M$). It was found bcl-2 gene was decreased dose dependently, the expression level of bax gene of THP-1 cells treated with $100{\mu}M$ of decursin was about 3 times higher than those of control, and p53 gene was increased In the same concentration($100{\mu}M$), p53 gene was increased dose dependent manner. In protein express, bcl-2 and p53 protein showed a tendency to decrease. bax was increased about 4 fold. Therefore decursin is a useful chemotherapeutic agent against leukemia.

• 대한방사선치료학회지
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• 제30권1_2호
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• pp.185-189
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• 2018

목 적 : Set-up Line을 유지하면서 치료 중 씻을 수 있도록 하여 방사선 치료 시 환자의 삶의 질 만족도를 평가하였다. 대상 및 방법 : 2018년 1월 본원에 내원한 환자 60명을 대상으로 반복되는 방사선 치료 시 환자의 불편사항을 조사하였다. 가장 큰 불편사항으로 치료 중 씻지 못하는 것에 대부분 불편함을 호소하였고(64 %), 이에 대한 해결책으로 Set-up Line 위에 외과용 테이프를 부착하여 치료 기간 중 환자분이 씻을 수 있도록 하였다. 외과용 테이프를 적용한 환자 총 50명을 대상으로 5점 기준으로 만족도를 조사하였다(1점 매우 불만족한다, 2점 불만족한다, 3점 보통이다, 4점 만족한다, 5점 매우 만족한다). 50명 중 40명은 치료를 처음 시작한 환자를 대상으로, 10명은 치료 진행 중인 환자를 대상으로 각각 평가를 진행하였다. 결 과 : 1차 설문조사에 응한 환자의 성별은 여성 68 %, 남성 32 %이였으며, 나이는 50대 이하 34 %, 50~60대 38 %, 60대 이상이 28 %로 나타났다. 치료부위는 유방 57 %, 흉부 13 %, 골반부 10 % 등으로 나타났다. 외과용 테이프를 적용 후 2차 설문조사한 결과 치료를 시작한 환자 40명 중 여성 25명, 남성 15명으로 조사되었고, 치료부위는 유방 22명, 골반부 18명으로 나타났다. 5점 척도 기준의 만족도에서 1-3점이 5명, 4-5점이 35명(1점 2명, 2점 2명, 3점 1명, 4점 17명, 5점 18명)으로 매우 만족 45 %, 만족 43 %로 나타났다. 치료를 진행 중에 적용한 환자에 대한 설문조사 결과에서 10명 중 여성 9명, 남성 1명으로 조사되었고, 치료부위는 유방 8명, 골반부 2명으로 나타났다. 5점 척도 기준의 만족도에서 1점이 1명, 5점이 9명으로 90 %가 매우 만족하는 것으로 조사되었다. 결 론 : 방사선 치료 시 정확성도 중요한 만큼 암환자의 삶의 질 향상도 고려해야 할 사항이다. 외과용 테이프를 적용 후, 치료를 시작한 환자의 88 %, 치료 진행 중 적용한 환자의 90 %가 만족을 보임을 알 수 있었다. 특히, 치료 진행 중 적용한 환자에게 더 높은 만족도를 보였다. 이를 통해 모든 환자에게 적용이 어렵다면 불편함을 호소하는 환자에게 선택적으로 적용하는 것도 암환자 삶의 질을 높이는데 큰 도움이 될 것을 판단된다.

• 대한간호학회지
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• 제2권1호
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• pp.35-47
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• 1971

This is a research on general evaluation of the nursing profession which is a professional job, a suitable calling to women and is developing academically day by day. The author gave some questions to the patients, doctors, people, student nurses-themselves and got the following results; (A) General concept about nursing profession A nurse is a member, of a medical team who works for people′s health promotion(50.8%). The reason that the nursing profession is a good one is that it is a rewarding job to care for sick patients(78.9%). The spirit is the most important factor for the nurse(84.8%) and the nursing profession is a suitable calling to women (76%). The description of nurses as "The angels in white dress" is an appropriate one (44.6%) or only a beautiful expression(47.4%) (B) Nurses as actually seen by doctors and patients. They work only obligatorily (47.8%)-Doctors They try to relieve, the patient′s physical discomforts in all sincerity (65.6%), also they to decrease the patient′s mental apprehension (56.7%). (C) Satisfaction in the nursing profession. Nurses satisfaction in the nursing profession is general(68.8%) and student nurses satisfaction in selecting nursing is fulfilled (50.9%). One reason for dissatisfaction among nurses and student nurses is people's failure to understanding the nursing profession(40.1%), One reason for satisfaction is that it is a rewarding job caring for sick patients(35%). (D) Is the nursing professional job? People think the nursing profession is a professional job like doctors or lawyers (60.2%). (E) Are they academic? People think the nurses are academic(37.8%) but nurses read only interesting items in the "Journal of Korean Nurse"(67.7%). (F) Opinions about nurses′going out of the country. Doctors and nurses agree that after 1-2 years′experience in this country(78.5%) and student nurses want to go out where there is on opportunity(73.1%). Student's purpose of going out is to enrich their stock of information(71.3%), doctors think, it is for training in nursing knowledge and skills (47.8%). (G) Opinions about nurse′s social affairs. They want nurses to be controlled(44.4%) and also think that the nurse's demonstration in the National Conte. was reasonable (36.3%). (H) Would you make your daughter a nurse? They favour their daughter′s becoming a nurse(17.4%) because they think it is a rewarding job to care for sick patients(42.5%).

• Nutritional Sciences
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• 제8권1호
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• pp.28-34
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• 2005

To examine the combined effects of a high-protein diet and aerobic exercise on body weight and composition and blood lipid profiles in overweight women, 30 young women were recruited and placed into three groups: The high-protein diet and exercise group (HPE), the exercise-only group (EXO) and the control group (CON) (30$\pm$3%, 27$\pm$2%, and 29$\pm$3% body fat, respectively) for an 8-week experimental period. Daily diet included 25% isolated soybean protein (>90% protein, approximately 400 kcal) combined with each subject s usual diet for the HPE group. The exercise program consisted of aerobic-type exercises undertaken >3 times/wk and for>30 min/session at 50-60% of maximal capacity. Physical fitness, body composition, serum total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), triglycerides (TG) and glucose were measured before and after the experiment. Maximal aerobic capacity increased by the end of experiment in both the HPE (from 27.2$\pm$3.5 to 35.l$\pm$5.9 ml/kg/min, p<0.01) and EXO (from 30.3$\pm$5.4 to 33.8$\pm$3.8 mㅣ/kg/min, p<0.05) groups. Percent body fat decreased by 3.3% (p<0.01) in the HPE group and by 1.5% (p<0.05) in the EXO group by the end of the experiment, but not in the CON group. Lower back strength and agility increased only in the HPE group. In the HPE group, TC decreased from 168$\pm$20 to 155$\pm$18 mg/dL and HDL-C increased from 57$\pm$l0 to 61$\pm$9 mg/dL in HPE (p<0.01). But TC and HDL-C did not change in the EXO and CON groups. TG and glucose did not vary among the groups. Although the EXO group showed a similar outcome to that of the HPE group, a favorable change in body composition and blood lipids as well as an improvement in aerobic capacity was more marginal in the latter group.

• Journal of Nutrition and Health
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• 제9권4호
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• pp.28-35
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• 1976

To know changes of the food preferences and the practice of pica during pregnancy, ninety two women in the latter half of pregnancy were interviewed in April, 1976 at ten medical centers in Seoul. They were average 27.1 years old, and mostly middle class. 83.7% of the total subjects felt the changes of food preferences due to pregnancy within the first trimester. 60.9% had vomiting as well as losing their appetite and 17.3% vomited three or more times daily which might induce difficulties of water and electrolytes balance in body. The preferences about foods, the taste of foods, and various dishes cooked during morning sickness were changed significantly and showed in lower scores of likes and higher scores of dislikes than those before pregnancy. Particularly, cooked rice and kimchi indicated the increase of more than 50% in dislikes. The preferences after the morning sickness were turned back to those before pregnancy. Desire for water through foods like soft drinks, juice, ice cream, and gamju and salty foods seemed to be spontaneous during pregnancy. A majority of the subjects had three meals and no snack had included more snacks instead of meals during losing appetite and thereafter, had more frequent meals and snacks. Superstitions about chicken, squid, and cuttlefish for pregnant women were prevalent. 11.9% tabooed chicken because of harm for fetus. On the contrary, intended higher inclusions of milk, meat and dried small sardines would be helpful to satisfy the increased recommended allowances of calcium and protein for them. The practice of pica was found in 5.4% and rice was the only real item mentioned. Pica such as amylophagia or geophagia often reported in the U.S. was not answered in this study.

• 여성건강간호학회지
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• 제9권2호
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• pp.105-112
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• 2003

The survey was conducted to look out the characteristics of menstruation and it's management, menstrual attitudes and degree of dysmenorrhea in the adult women. The subjects were 601 women, aged 20 year old and over, selected by convenient sampling. The results were as follows; 1. The mean age of the subjects was 29.1 years, the subjects were consisted of 346 unmarried and 304 delivery experienced person. 2. The characteristics of menstruation were as follows ; irregular 167 person(27.8%), painful 451 person(75%), mean score of pain was 5.9 point and first day was most severe(45.1%). On the while, they have used the method to manage the pain such as "endure 50.8%", "to have a medicine 31.5%". 3. Menstrual attitudes were as follows; attitudes was negative such as it was meaningful as a woman (78.9%), only for birth a baby (51.6%), and menstruation was acceptable (42.9%), hope to get away(28.8%). 4. The degree of dysmenorrhea was a significant difference by age(F=4.0, P<0.01). Especially, in the subcategory, it was significant except for water retension. That is, lower concent ration(F=2.60, p<0.05), negative affect(F=3.09, p<0.05), behavior change(F=6.41, p<0.050), pain(F=3.89, p<0.01), autonomic nerve response(F=2.80, p<0.05). We can conclude there were many women to have negative attitudes to menstruation and first day was most severe dysmenorrhea and it was different by age. From this results, we may suggest as follows; 1. We suggest the program for women to have a positive attitudes will be developed. 2. We can suggest that we need to develop the active and effective method to control dysmenorrhea in the first day during menstruation.

• 한국콘텐츠학회논문지
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• 제18권5호
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• pp.319-329
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• 2018

챗봇 서비스가 단순 테스크 기능을 벗어나 심리상담, 친구 역할과 같이 사람과 같은 수준의 지능을 가진 강인공지능으로 진화하기 위해 기술적 연구가 활발히 이루어지고 있다. 그러나 실제로 챗봇을 사람으로 인지하기 위해서 일관된 성격을 부여하는 것이 중요함에도 그에 관한 기준이 부재하고 연구 또한 미비하다. 따라서 본 연구는 챗봇의 사용 목적과 사용자 유형에 따라 선호되는 챗봇의 성격에 관해서 연구하였다. 사용 목적은 심심할 때, 심리상담, 테스크(task)로 구분하였고 성격은 DISC이론의 주도형(D), 사교형(I), 신중형(C), 안정형(S)으로 4가지로 구분하였다. 사용자 인터뷰를 통해 사용 목적에 따라 선호하는 챗봇의 나이, 성별, 성격과 심심할 때 챗봇에게 기대하는 콘텐츠 및 말투에 대해서 설문 문항을 도출하였다. 설문한 결과 심심할 때는 주로 사람중심의 성격인 I, S, 테스크 목적일 때는 일 중심 성격인 D,C, 심리상담일 때는 느린 성격인 C,S를 선호하는 것으로 나타났다. 여성은 심리상담을 제외하고 중성을 선호했고 남성은 목적에 상관없이 여성을 선호하였다. 선호하는 연령대는 심심할 때는 또래이거나 어린 나이, 심리상담의 경우 또래이거나 다소 연상, 테스크 목적일 때는 주로 30대가 선호되었다. 심심할 때 기대하는 바에 있어서 대부분의 연령대가 정보를 선호하였지만 20대는 재미가 앞섰고 50-70대는 공감 및 정서적 안정감을 중시하는 것으로 나타났다. 말투에 있어서 20대와 6-70대는 존댓말에 대한 선호가 적지만 3-50대는 존댓말을 선호하였다. 결론적으로 심심할 때는 자신보다 낮은 존재, 테스크 목적일 때는 효율성, 심리상담의 경우에는 신중하게 듣는 태도를 선호하는 경향을 보임을 알 수 있었다. 이러한 결과는 챗봇의 서비스 목적에 따라 적합한 정체성을 설정하는데 유용한 가이드가 될 것으로 기대한다.

• 산업식품공학
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• 제14권1호
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• pp.35-40
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• 2010

고춧가루의 매운 맛 등급화 가능성을 검토하고자 mass spectrometer를 바탕으로 한 전자코를 활용하여 순한 맛 고춧가루와 매운 맛 고춧가루의 비율 달리하여 측정하였다. 고춧가루의 질량 스펙트럼을 토대로 판별 함수 분석을 수행한 결과 매운 맛 고춧가루의 비율과 고춧가루의 무게에 따라 판별이 이루어졌으며 DF1의 $R^{2}$는 0.9946, F값은 355.65이고, DF2의 $R^2$는 0.9889, F값은 172.60으로 나타났다. 매운 맛 고춧가루의 비율이 증가할수록 DF1의 양의 방향에서 음의 방향으로 이동되며 막대그래프상의 상대적 비교치와 비례적인 관계를 보여주었다. 한편 같은 비율에서 고춧가루의 무게가 증가할수록 DF2의 음의 방향에서 양의 방향으로 향하는 경향을 보이며 분리되었다. 고춧가루를 각각의 매운 맛 비율별로 2.0 g만을 취하여 분석한 결과, 매운 맛 비율이 증가할수록 DF1의 양의 방향에서 음의 방향으로 이동되는 경향을 보이며 분리가 되었고 DF1의 $R^{2}$는 0.9977, F값은 766.98이고 DF2 의 $R^{2}$는 0.8677, F값은 11.80으로 나타났다. Capsaicin을 무게를 달리하여 측정한 후 DFA를 수행한 결과 DF1의 $R^{2}$는 0.9890, F값은 165.17이고 DF2의 $R^{2}$는 0.9219, F값은 21.64로 나타났다. Capsaicin의 무게가 증가할수록 DF1의 양에 방향에서 음에 방향으로 향하는 경향으로 분리되어 MS를 바탕으로 한 전자코를 이용하여 고추의 매운 맛 등급화가 가능하였다. 전자코에 의한 분석결과는 HPLC에 의한 분석결과와 높은 상관관계를 나타냈다 ($R^{2}$=0.962).