• Culinary science and hospitality research
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• v.22 no.5
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• pp.134-150
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• 2016

The purpose of this study is to investigate the recognition and preference for temple food between Korea and foreign national temple-stay participants. In order to achieve the research purpose, 220 research questionnaires were distributed to Korean and foreigners who have participated in a temple-stay. T-test and ANOVA analyses were performed for this study. The findings are summarized as follows. The highest recognition item for Korean temple food that the subjects perceived was 'I think Korean temple food is a medicinal food.'(4.31 points). In the value recognition score for Korean temple food, Asians(4.58 points) are relatively higher than Korean (4.23 points), North American (4.13 points) and European (3.94 points) participants. Participants in Asia appeared relatively higher than the others in the preference score on Korean temple food. The higher globalization strategy items of Korean temple food that the subjects perceived were 'Korean temple food needs a storytelling marketing'(3.94 points) and 'Korean temple food needs a modernization of cookware'(3.90 points).

• Microbiology and Biotechnology Letters
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• v.35 no.4
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• pp.278-284
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• 2007

A novel screening strategy for salt-resistant antimicrobial peptides from a M13 peptide library was developed. Fusion of MSI-344, a magainin derivative and indolicidin to pIII coat proteins did not significantly affect viability of the recombinant phages, which indicated that the pIII could neutralize toxicity of the antimicrobial peptides and therefore it is possible to construct antimicrobial peptide library in Escherichia coli. On the basis of the conserved sequence of ${\alpha}$-helical antimicrobial peptides, a semi-combinatorial peptide library was constructed in which the peptides were displayed by pIII. To remove hemolytic activity from the library, the phages bound to red blood cells were removed, and the subtracted phage library was screened for binding to target bacteria Pseudomonas aeruginosa and Staphylococcus aureus under high salt concentrations. The screened peptides showed relatively low antimicrobial activity against the target bacteria. However, antimicrobial activities of the screened peptides P06 and S18 were not affected by the cation concentrations of 150 mM $Na^+$, 2 mM $Mg^{2+}$ and 2 mM $Ca^{2+}$ without significant hemolytic activity. This screening strategy that is based on binding capacity to target cells provides new potential to develop salt-tolerant antimicrobial peptides.

• Clinical and Experimental Pediatrics
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• v.54 no.11
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• pp.473-476
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• 2011

Primary hypokalemic periodic paralysis (HOKPP) is an autosomal dominant disorder manifesting as recurrent periodic flaccid paralysis and concomitant hypokalemia. HOKPP is divided into type 1 and type 2 based on the causative gene. Although 2 different ion channels have been identified as the molecular genetic cause of HOKPP, the clinical manifestations between the 2 groups are similar. We report the cases of 2 patients with HOKPP who both presented with typical clinical manifestations, but with mutations in 2 different genes ($CACNA1S$ p.Arg528His and $SCN4A$ p.Arg672His). Despite the similar clinical manifestations, there were differences in the response to acetazolamide treatment between certain genotypes of $SCN4A$ mutations and $CACNA1S$ mutations. We identified p.Arg672His in the $SCN4A$ gene of patient 2 immediately after the first attack through a molecular genetic testing strategy. Molecular genetic diagnosis is important for genetic counseling and selecting preventive treatment.

• Korean Journal of Adult Nursing
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• v.16 no.1
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• pp.49-59
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• 2004

Purpose: This study is a descriptive research study to measure the quality of life of those who suffer from breast cancer and take the chemotherapy. Method: The Subjects were 70 breast cancer patients who took the chemotherapy from September 2 to October 31, 2003. Quality of life was measured by Ferrell's measurements. Result: Quality of life indicators were spiritual domain=6.44, physical domain=5.45, social domain=4.15, and mental domain=3. 95. Whole quality of life was 4. 68 out of 10 points. The quality of life of those with a practicing religion was significantly higher than those without(F=3.88, P=0.026). Subjects who were less than 2 months post-operation had higher points in the physical domain than those who were more than 2 months post-operation (t= 2.76, p=0.007). Subjects who had less than 4 treatments of chemotherapy had higher points in the physical domain than those who had more than 4 treatments of chemotherapy (t=2.03, p=0.046). Conclusion: The results of this study serve as a meaningful source to promote quality of life of breast cancer patients who undergo chemotherapy. The results can also be applied to the development of education programs and counseling materials for chemotherapy patients. Health care strategy can also raise the quality of life of brest cancer patients.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.35 no.1
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• pp.161-168
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• 2012

Recently, Social Commerce that provides customer with cheap deals is under the spotlight. The purpose of this study is to propose how to use social commerce on small restaurant business, which encompass almost a half of entire deals. We analyzed each element from the last transaction data of three social commerce company and survey obtained from the restaurant business. As a result, we can find that the purpose of promoting, the location of restaurant, whether is franchise or not, price and menu composition have an effect on sales of coupon. Based on these results, we proposed two step approaches to use the social commerce company. The first step is to decide whether social commerce is used or not and the second step is to define the detail content of deal including the social commerce company. We convinced that our proposed strategy is very helpful to the small restaurant which considers utilization of social commerce company.

• Journal of Microbiology and Biotechnology
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• v.25 no.1
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• pp.81-88
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• 2015

This study describes a novel strategy to regulate the metabolic flux for lactic acid production in Lactobacillus casei. The ldhL gene encoding _L-lactate dehydrogenase (L-LDH) was overexpressed in L. casei, and a two-stage oxygen supply strategy (TOS) that maintained a medium oxygen supply level during the early fermentation phase, and a low oxygen supply level in the later phase was carried out. As a consequence, a maximum L-LDH activity of 95.6 U/ml was obtained in the recombinant strain, which was over 4-fold higher than that of the initial strain. Under the TOS for L. casei (pMG-ldhL), the maximum lactic acid concentration of 159.6 g/l was obtained in 36 h, corresponding to a 62.8% increase. The results presented here provide a novel way to regulate the metabolic flux of L. casei for lactic acid production in different fermentation stages, which is available to enhance organic acid production in other strains.

• Journal of Power Electronics
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• v.16 no.1
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• pp.351-361
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• 2016

Power quality is a critical issue in distribution systems, where a dynamic voltage restorer (DVR) is commonly used to mitigate the voltage disturbances for loads. This paper deals with a nonlinear control for the three-phase four-wire (3P-4W) DVR under a grid voltage unbalance and nonlinear loads in the distribution system, where a novel control scheme based on the feedback linearization technique is proposed. Through feedback linearization, a nonlinear model of a DVR with a PWM voltage-source inverter (VSI) and LC filters is linearized. Then, the controller design of the linearized model is performed by applying the linear control theory, where the load voltages are kept constant by controlling the d-q-0 axis components of the DVR output voltages. To keep the load voltage unchanged, an in-phase compensation strategy is employed, where the load voltages are recovered to be the same as the previous voltage without a change in the magnitude. With this strategy, the performance of the DVR becomes faster and more stable even under unbalanced source voltages and nonlinear loads. The validity of the proposed control strategy has been verified by simulation and experimental results.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.6
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• pp.3675-3684
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• 2014

This study examined the relationships among body perception, anxiety, psychological flexibility, and abnormal eating habits of college students. Data was collected through a self reported structured questionnaire from 289 Korean college students using convenient sampling methods from April 20 to June 30, 2013. Multiple linear regression revealed the subjective body perception (${\beta}$=0.28, p<.001), ideal body image (${\beta}$=-0.15, p=.004), anxiety (${\beta}$=0.21, p<.001), and psychological flexibility (${\beta}$=-0.13, p=.032) to be significant predictors of abnormal eating habits of college students. These variables accounted for 26% of abnormal eating habits (F=17.42, p<.001). Therefore, as a strategy for reducing abnormal eating habits, therapeutic nursing intervention will be needed to improve the psychological flexibility and control anxiety as well as correct the distorted body perception.

• Biomolecules & Therapeutics
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• v.26 no.3
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• pp.313-321
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• 2018

Anti-cancer drug resistance is a major problem in colorectal cancer (CRC) research. Although several studies have revealed the mechanism of cancer drug resistance, molecular targets for chemotherapeutic combinations remain elusive. To address this issue, we focused on the expression of cellular prion protein ($PrP^C$) in 5-FU-resistant CRC cells. In 5-FU-resistant CRC cells, $PrP^C$ expression is significantly increased, compared with that in normal CRC cells. In the presence of 5-FU, $PrP^C$ increased CRC cell survival and proliferation by maintaining the activation of the PI3K-Akt signaling pathway and the expression of cell cycle-associated proteins, including cyclin E, CDK2, cyclin D1, and CDK4. In addition, $PrP^C$ inhibited the activation of the stress-associated proteins p38, JNK, and p53. Moreover, after treatment of 5-FU-resistant CRC cells with 5-FU, silencing of $PrP^C$ triggered apoptosis via the activation of caspase-3. These results indicate that $PrP^C$ plays a key role in CRC drug resistance. The novel strategy of combining chemotherapy with $PrP^C$ targeting may yield efficacious treatments of colorectal cancer.

• Asian-Australasian Journal of Animal Sciences
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• v.16 no.3
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• pp.359-367
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• 2003

Supplementary feeding strategies were evaluated from pre-calving throughout lactation on 24 dual-purpose Mpwapwa breed cows in their second or greater lactation, weighing 246-455 kg. The Mpwapwa breed is an established breed of 4 Bos indicus breeds and 8% of Bos taurus. The cows were penned and stall-fed individually. Eight weeks before calving to eight weeks after calving, the cows were divided into two groups and offered hay ad libitum with either 2 kg DM (L) or 4 kg DM/day (H) concentrates. Nine weeks after calving half of the cows on L-level continued with 2 kg DM/day (L-L) while the remainder received 4 kg DM concentrate daily (L-H). Half of the cows on H-group continued with 4 kg DM/day (H-H) while the remainder received 2 kg DM/day (H-L). The concentrate mixture comprised of sunflower seed cake (33%) and maize bran (67%). The cows consumed all the concentrate offered. Hay DM intake was similar (6.8 kg/day) and tended to decrease the last two weeks before calving increased again after calving. Live weight change and body condition score were similar across treatments before calving but differed after calving (p<0.05). Heavier cows with higher condition score pre-calving had a higher body weight loss and regained weight later. After treatment reallocation, live weight change and condition differed between treatments (p<0.05). Calves were allowed to suckle milk from one quarter. The amount of milk suckled and calf weight gains were not significantly different between treatments. The cows were removed from the experiment when the milk yield was below 4 kg per day. Cows on treatment H produced 6.2 kg and on treatment L 5.0 kg saleable milk/day (p<0.05) during the first 8 weeks post partum. During the period 9-18 weeks post partum the saleable daily milk on H-H, L-H, H-L and L-L were 5.2, 4.8, 4.7 and 4.3 kg, respectively (p>0.05).