• Title/Summary/Keyword: 4-AP

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Comparison of Black-pigmented Bacteroides using 16S rRNA analysis between Chronic periodontitis and Aggressive Periodontitis (만성 치주염과 급속 파괴성 치주염에서의 흑색색소 형성 Bacteroides의 분포도 비교)

  • Shin, Chul-Woo;Choi, Bong-Kyu;Moon, Ik-Sang;Kim, Chong-Kwan;Cho, Kyoo-Sung
    • Journal of Periodontal and Implant Science
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    • v.34 no.2
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    • pp.255-268
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    • 2004
  • The purpose of the research is to compare the distribution of Black-pigmented Bacteroides between Chronic Periodontitis and Aggressive Periodontitis. P. gingivalis, P. intermedia and P. nigrescens were examined in order to evaluate their distribution in patients with Chronic Periodontitis(CP) and Aggressive Periodontitis(AP). PCR and dot-blots hybridization of 16s rRNA gene were used to compare bacterial distribution of two groups - CP group and AP group, which were divided into two subgroups. Subgingival plaque taken from the diseased sites(pocket $depth{\geq}6$ mm) and healthy sites(pocket $depth{\leq}3$ mm) were grouped into the experimental group and the control group. The result are as follows ; 1. The distribution of P. gingivalis was 98.33% for chronic Periodotitis(CP), 94.17% for Aggressive Periodontitis(AP), the distribution of P. intermedia was 77.50% for CP, 64.17% for AP, and the distribution of P. nigrescens was 35.00%, 29.17%. In all 3 types of bacteria, CP group showed higher distribution compared to AP group, but only P. intermedia showed statistically significant difference. 2. In the case of CP, every type of bacteria showed higher distribution in the experimental group with statistically significant difference. 3. In the case of AP, every type of bacteria also showed higher distribution in the experimental group, but P. gingivalis and p..intermedia showed the result with statistically significant difference, and the other did not 4. In 3 all bacteria type, N-AP showed higher distribution than N-CP without statistically significant difference These results suggest that the comparison of the distribution of Bacteroides between Chronic Periodontitis and Aggressive Periodontitis has no statistically significant difference, except P. intermedia.

Conversion of Gycosylphosphatidylinositol (GPI)-Anchored Alkaline Phosphatase by GPI-PLD

  • Moon, Young-Girl;Lee, Hyun-Jung;Kim, Mee-Ree;Myung, Pyung-Keun;Park, Soo-Young;Sok, Dai-Eun
    • Archives of Pharmacal Research
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    • v.22 no.3
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    • pp.249-254
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    • 1999
  • Enzymatic conversion of brain glycosylphosphatidylinositol-linked alkaline phosphatase (GPI-AP), amphiphilic, was examined. When GPI-AP was incubated with glycosylphosphatidylinositol-specific phospholipase D (GPI-PLD), a negligible conversion of GPI-AP to hydrophilic form was observed. The inclusion of monoacylglycerols enhanced the enzymatic conversion, although the action of monoacylglycerols differed greatly according to the size of acyl group; the enzymatic conversion was enhanced considerably in the presence of monoacylglycerols possessing acyl group of longer chain length ($C_{10-}C_{18}$), which monoacylglycerols with acyl moiety of shorter length ($C_{4-}C_{8}$) did fail to augment the enzymatic conversion. Noteworthy, monooleoylglycerol was much more effective than the other monoacylglycerols in promoting the enzymatic conversion, indicating a beneficial role of the unsaturation in acyl chain. Meanwhile, ionic amphiphiles such as monohexadecyllysophosphatidylcholoine and palmitoyl-carnitine decreased the enzymatic conversion of GPI-AP in a concentration-dependent manner, with monohexadecyllysophosphatidylcholine and palmitoyl-carnitine deceased the enzymatic conversion of GPI-AP in a concentration-dependent manner, with monohexadecyllysophosphatidylcholoine being more inhibitory than palmitoylcarnitine. Separately when GPI-AP was exposed to various oxidants prior to the incubation with GPI-PLD, a remarkable decrease of the enzymatic conversion was observed with hypochlorite and peroynitrite generators, but not $H_{2}O_{2}$. In further study, hypochlorite was found to inactivate GPI-PLD at low concentrations ($3~100{\mu}M$). From these results, it is suggested that the enzymatic conversion of GPI-AP by GPI-PLD may be regulated in vivo system.

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A Study about Implementation Method of Multi-Interface Multi-Channel 2.4GHz Active RFID Reader Protocol (다중인터페이스 다중채널 2.4GHz 능동형 RFID 리더 프로토콜 구현방법에 관한 연구)

  • Kim, Dong-Hyun;Lee, Chae-Suk;Kim, Jong-Doek
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.14 no.4
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    • pp.1005-1014
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    • 2010
  • When reader collect tags, we found that they tend to get together to specific interface in Multi-Interface Multi-Channel 2.4GHz Active RFID system. To solve this problem, we designed the LP-Combind and AP-Balanced protocol for load distribution between interfaces, then verified its superiority of the performance through the simulation. There are three problems to implement designed protocols in hardware of firmware-level. first, tag selects randomly the channel of reader and reader need the method which can change the channel of tags. second, reader has the synchronization problem between reader and tag. third, reader has problem that MCU of reader have to operate simultaneously dual interface. To slove this problems, we designed the message and implemented method for tag channel change and the protocol in order to adjust synchronization between reader and tag, Therefore, we compared and analyzed the performance of protocols by experiment. If LP windows size is same, the performance of LP-Combined protocol and AP-Balanced protocol which lower collision probability by its load distribution is more outstanding than single interface protocol performance.

A Study on Characteristic of Eco-friendly Propellant Using GUDN/BTATz (GUDN/BTATz를 적용한 친환경추진제 특성 연구)

  • Jeon, Su-a;Won, Jong-ung;Park, Sung-jun;Park, Jung-ho;Choi, Sunghan
    • Journal of the Korean Society of Propulsion Engineers
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    • v.24 no.4
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    • pp.41-47
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    • 2020
  • This study aims to develop eco-friendly propellant that reduce the generation of harmful gases such as HCl gas and increase the emmision of nitrogen gas emissions. For this purpose, GUDN(N-Guanylurea dinitramide) and BTATz(3,6-bis(1H-1,2,3,4-tetrazol-5-ylamino)-1,2,4,5-tetrazine), which are low carbon high nitrogen materials, were used instead of AP(Ammonium Perchlorate) and Al(Aluminium), which are gernerally used in solid propellant. The prepared propellants were analyzed for mechanical properties and combustion characteristics, performance and AGARD smoke classification. Compared with AP/Al propellant, GUDN/BTATz propellant tended to decrease mechanical and combustion rate. Also, as a result of the static test after the production of the 4-inch motor, the performance of combustion of the GUDN/BTATz propellant decreased, but it was confirmed that the secondary smoke was improved by reducing harmful gases such as HCl gas.

Measurement-based AP Deployment Mechanism for Fingerprint-based Indoor Location Systems

  • Li, Dong;Yan, Yan;Zhang, Baoxian;Li, Cheng;Xu, Peng
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.4
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    • pp.1611-1629
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    • 2016
  • Recently, deploying WiFi access points (APs) for facilitating indoor localization has attracted increasing attention. However, most existing mechanisms in this aspect are typically simulation based and further they did not consider how to jointly utilize pre-existing APs in target environment and newly deployed APs for achieving high localization performance. In this paper, we propose a measurement-based AP deployment mechanism (MAPD) for placing APs in target indoor environment for assisting fingerprint based indoor localization. In the mechanism design, MAPD takes full consideration of pre-existing APs to assist the selection of good candidate positions for deploying new APs. For this purpose, we first choose a number of candidate positions with low location accuracy on a radio map calibrated using the pre-existing APs and then use over-deployment and on-site measurement to determine the actual positions for AP deployment. MAPD uses minimal mean location error and progressive greedy search for actual AP position selection. Experimental results demonstrate that MAPD can largely reduce the localization error as compared with existing work.

Chunghyuldan Downregulates the Activation of Transcription Factors NF - kB and AP-1 of BV-2 Cells Induced by Lipopolysaccharide

  • WEE Sung-SooK;BAE Eun-Ah;PARK Jin-Sun;KIM Hee-Sun;CHo Hee Jae;Ryu Jong-Hoon;KIM Dong-Hyun
    • Biomolecules & Therapeutics
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    • v.13 no.4
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    • pp.214-219
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    • 2005
  • Chunghyuldan (Qingxuedan in Chinese) (CHD) has been used for patients with atherosclerosis and brain ischemia in Korea. To evaluate antiischemic activity of CHD, its antiinflammatory effect in lipopolysaccharide-induced BV-2 cells was investigated. CHD potently inhibited nitric oxide (NO) production in LPS-induced BV-2 cells with an $IC_{50}$ value of 4.8${\mu}g/ml$. CHD did not only inhibit mRNA and protein expression levels of inducible NO synthase and cyclooxygenase-2 in LPS-induced BV-2 cells, but also repressed mRNA expression levels of proinflammatory cytokines IL-l$\beta$ and TNF-$\alpha$. CHD also downregulated the activation of NF-kB and AP-l transcription factors induced by LPS. These results suggest that CHD may improve inflammatory brain ischemia by the downregulation the activation of NF-kB and AP-l transcription factors.

Serological Analysis of Leptospira Interrogans Isolated in Korea by Cross-agglutinin Adsorption Method (Cross Agglutinin Adsorption 방법에 의한 렙토스피라균의 혈청학적 분석(1985))

  • Oh, Hee-Bok;Park, Kyung-Seok;Cho, Min-Kee
    • The Journal of the Korean Society for Microbiology
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    • v.21 no.3
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    • pp.337-343
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    • 1986
  • To clarify the existing serological varieties of Leptospira interrogans in Korea, 15 isolates of 1985 were serologically studied by cross agglutinin adsorption test. Fourteen cultures except HS 7 belonged to serogroup Icterohemorrhagiae. Isolate HM 3 and HV 8 were considered to belong to serotype mwogolo by their low residual homologous antibody(0.08 to 6.25%) after cross adsorption with serotype mwogolo referene culture and antiserum. Both residual homologous antibody of isolate HS 7 and serotype canicola reference culture remained 1.56%, accordingly HS 7 proved to belong to serotype canicola. The agglutinogens of isolate HY2, AP3, AP4, AP7 and AP9 are considered to closely related to serotype mwogolo, and HM4 and HS6 to serotype birkini, which remained to be further studied. The remaining 5 strains(HY1, HS5, HY10, 310-9, 310-19) could not be attached to any known serotype of Icterohemorrhagiae serogroup by cross adsorption test.

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Dynamic Channel Assignment Scheme Using Graph Coloring in Femtocell Networks (펨토셀 네트워크에서 그래프 컬러링을 이용한 동적채널할당 방법)

  • Kim, Se-Jin;Cho, IlKwon;Kim, Yi-Kang;Cho, Choong-Ho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38B no.4
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    • pp.257-265
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    • 2013
  • In this paper, we proposed a Dynamic Channel Assignment (DCA) scheme called Graph Coloring based DCA (GC-DCA) to improve system performance for downlink femtocell networks with high density femto Access Point (AP) deployments. The proposed scheme consists of two steps: one is a femto AP grouping step considering interference and the other is a DCA step considering Signal to Interference plus Noise Ratio (SINR) for femto User Equipments (UEs). Simulation results show that the proposed GC-DCA outperforms other schemes in terms of the mean femto UE capacity and probability of femto UEs which have capacities less than a given transmit rate.

Seasonal Abundance of Deer and Horse Flies (Diptera: Tabanidae) in the Northern Part of Gyeonggi-do, Republic of Korea

  • Suh, Sang Jae;Kim, Heung Chul;Chong, Sung Tae;Kim, Myung Soon;Klein, Terry A.
    • Parasites, Hosts and Diseases
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    • v.53 no.3
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    • pp.307-314
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    • 2015
  • The seasonal abundance of horse and deer flies (family Tabanidae) was analyzed using Mosquito Magnet$^{(R)}$ traps at 5 sites located near/in the demilitarized zone, northern Gyeonggi-do, Republic of Korea from late April to early October for 4 consecutive years (2010-2013). A total of 2,999 horse and deer flies (tabanids) belonging to 5 genera and 20 species were collected. Chrysops mlokosiewiczi (90.9%) was the most frequently collected, followed by Haematopota koryoensis (4.8%) and C. suavis (1.0%). The remaining 17 species comprised only of 3.3% of all species collected. C. mlokosiewiczi demonstrated bimodal peak populations during mid-June and early August, while H. koryoensis demonstrated a unimodal peak during mid-July. Overall numbers of tabanids collected were influenced by the previous year's winter temperatures and precipitation. Population abundance was influenced by habitat with most of tabanids collected from habitats near forested areas, followed by rice paddies, and a beef farm.

The Study on Static Alignment Classification based on the Full Spine AP X-ray of Adults aged 30-39 (30대 성인의 골반, 척추 및 견갑대 정렬의 패턴 분석 - Full Spine AP X-ray 분석에 따른 -)

  • Park, Ji-Hyun;Hong, Seo-Young
    • Journal of Korean Medicine Rehabilitation
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    • v.20 no.2
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    • pp.89-99
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    • 2010
  • Objectives : This study was designed to analyze the pattern of asymmetrical alignment. Methods : This study was carried out with the data from comprehensive medical testing. 91 subjects aged 30-39 were evaluated by full spine AP X-ray. For pelvis, innominate measurement(IM), off centering measurement(OCM), ilium shadow measurement(ISM), major axis of obturator foramen(MaF), minor axis of obturator foramen(MiF) were analyzed. Spinal curvature and height of shoulder girdle were analyzed. Results : 1. In pelvis, It. posterior-inferior and it. inflare combination pattern was 38 cases(42.8%). 2. In spinal curvature, "reverse S" curve was 45 cases(49.4%) and "reverse C" curve was 30 cases(33%). 3. In shoulder girdle, It. superior pattern was 42 cases(46.1 %) and It. superior pattern was 39 cases(42.9%). 4. In whole body analysis, It. posterior-inferior and It. inflare pelvis, "reverse S" spinal curvature and It. superior shoulder girdle combination patten was 11 cases(12.1 %). This pattern is similar to Kendall's right handedness pattern and Zink's common compensatory pattern. Conclusions : Results from this investigation showed asymmetrical alignment in 30-39 years-old adults. This results are expected to contribute to classifying the alignment pattern in clinic and systemic treatment.