• Korean Journal of Poultry Science
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• v.25 no.3
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• pp.129-136
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• 1998

This experiment was carried out to investigate the effect of feeding system on performance in Korean Native Commercial Chicken. A total 864 birds produced from (Cornish ♂ X (Korean Native Chicken ♂ XRhode Island Red♀)♀ ] crossbreeds in National Livestock Research Institute, for 16 weeks. Feeding system of T1 and T$_2$ were same types from hatch to 8 weeks, starter diets(O~4 weeks, mash, ME 3,100kcal, CP 22.94%), grower diets(4~8 weeks, crumble, ME 3,100kcal, CP 19.31%). Nutrient content of finisher diets of T$_1$(pellet, ME 3,200kcal, CP 20.44%) was higher than T$_2$(mash, ME 3,100kcal, CP 14.88%) in order to improve meat quality for 8~16 weeks. Fertility and hatchability of Korean Native Commercial Chicken was 83.9% and 69.7%, respectively. Viabilities of T$_1$ and T$_2$ at 0, 4, 8, 12 and 16 weeks were 98.8%, 97.9%, 96.5% and 99.1%, 95. 8%, 92.8%, 90.3%, respectively. The viability of 0 to 8 weeks was not significantly in feed treatments, but 12 and 16 weeks was significantly T$_1$ higher than T$_2$(P<0.05). Body weights of T$_1$and T$_2$ at 4, 8, 12 and 16 weeks were 551g, 1,379g, 2,441g, 3,056g and 554g, 1,360g, 2,254g, 2,956g, respectively. The body weight of 0 to 8 weeks was not significantly feed treatments but 12 and 16 weeks was significantly T1 higher than T$_2$(P<0.05). Feed conversion of T$_1$ and T$_2$ to 4, 8,12 and 16 weeks were 1.91, 2.28, 3.34, 4.23 and 1.90, 2.28, 3.53, 4.46, respectively. The feed conversion of 0 to 8 weeks was not significantly feed treatments but 12 and 16 weeks was significantly T$_1$ lower than T$_2$(P<0.05). The ME intake 1 bird per 1 day of T$_1$ and T$_2$were 3S9kcal, 357kca1, respectively, not significantly feed treatments but CP intake were 24.8g, 20.3g, respectively. T$_2$ was lower than T$_1$(P$_1$ and T$_2$were 13,426kca1, 13,819Ykcal, respectively, not significantly feed treatments but CP requirement per kg body weight gain were 928g, 763g, respectively, T$_2$ was lower than T$_1$(P<0.05).

• Journal of Nutrition and Health
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• v.31 no.8
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• pp.1315-1323
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• 1998

Effect of oral taurine supplementation on plasma total and phospholidpid -fatty acid profiles and their metabolism were evaluated in healthy female adults. Among twenty five female volunteers(23.6$\pm$0.3 years old ) participated in the taruine supplementation program(6g taurine /day), twenty four subjects succesfully completed the 2 week program , and only nine subjects continued to take taurine for another 2 weeks. Levels of plasma fatty acids and taruine were measured by gas-liquid chromatobraphy and an automated amino acid analyzer based on ion exchange chromatography, respectively. Plasma taurine concentration s of the subjects were 108. 7$\pm$3.4 , 184.2$\pm$8.2 and 235.9$\pm$77.0$\mu$emol/L at 0 , 2 and 4 weeks of taurine supplementation. Fatty acid compositions and elongation and desaturation indices of polyunsaturated fatty acids (PUFA) in plasma total lipids were not influenced by oral taurine supplementation. However, fatty acid compositions and their metabolism in plasma phospholipids were significantly affected by taurine supplementation in female adults. Compared to the values for 0 week, the percentage of saturated fatty acids (SFA) in plasma phospholipid was significantly lowered at 2 weeks, but elevated at 4 weeks of taurine supplementation. In contrast , the percentage of phospholipid PUFA significantly increased at 2 weeks and decreased at 4 weeks of taurine supplementation from to the values for 0 weeks. Foru weeks of oral taurine supplementation signifinatly elevated the eongation index(20 : 4$\omega$6 ⇒22 : 4 $\omega$6, p<0.01), and decreased the desaturation index (20 : 3 $\omega$6 ⇒20 : 4 $\omega$6 , p<0.01) of $\omega$6 fatty acids in plasma phospholipids. Plasma taurine concentration was positively correlated with the percentage of 14 : 0 fatty acids and the enlongation index o f$\omega$3 fatty acids(20 : 5 $\omega$3 ⇒22 : 5 $\omega$3), and thenegatively correlated with the percentage of 20 : 0 in plasma phospholipids. These results indicate that oral taurine supplementation for 4 weeks signidicantly elelvated the percentage of SFA, and lowered the percentage of PUFA in plasma phospholipids with no influence on plasm total fatty aicd composition in healthy female adults.

• Journal of Periodontal and Implant Science
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• v.42 no.2
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• pp.33-38
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• 2012

Purpose: The goal of this study was to evaluate the clinical anitplaque and antigingivitis effects of a mouthrinse containing cetylpyridinium chloride (CPC), triclosan and dipotassium glycyrrhizinate (DPZ) in patients with gingivitis and mild periodontitis. Methods: Thirty-two subjects were randomized into 2 groups. The test group used a mouthrinse containing 0.05% CPC, 0.02% triclosan and 0.02% DPZ, while the control group used a placebo mouthrinse. At baseline, 2 weeks and 4 weeks, the papillary bleeding index (PBI), Turesky-Quigley-Hein plaque index (PI) and L$\ddot{o}$e-Silness gingival index (GI) were assessed. During the experimental period, the patients used the mouthrinse for 30 seconds, 4 to 5 times/day (10 mL/time) within 30 minutes after toothbrushing. Results: No adverse effects appeared in either the experimental or the control group. Regarding PBI, PI and GI values, statistical significance was detected between values at baseline and 2 weeks for both groups (P<0.05). In the experimental group, statistically significantly lower values were detected at 4 weeks compared to at 2 weeks. However, in the control group, no statistically significant difference was detected between the values at 2 weeks and 4 weeks. Additionally, the mean value after 4 weeks for the control group was slightly higher than the mean value after 2 weeks for the control group. Conclusions: This study for 4 weeks demonstrated that mouthrinses containing CPC, triclosan and DPZ may contribute to the reduction of supragingival plaque and gingivitis.

• Korean Journal of Poultry Science
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• v.13 no.2
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• pp.197-208
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• 1986

This experiment was conducted to find out the effects of the six different feeding methods on the development of body weight, testis, comb and pituitary gland, and the sexual maturity of White Plymouth Rock cockerels. From hatching to 22 weeks of age, the weights of whole body, testis, comb and pituitary gland, and the histological changes of testis and the semen characteristics were checked every other week. The results obtained in this expeniment were as follows: 1. The growth rates of the self-feeding groups were faster than those of the limited feeding groups (70 percent of the self-feeding) by about 2 weeks. The weights of testis and comb showed the most marked increase at 20 weeks of age in the self-feeding groups and at 22 weeks of age in the limited feeding groups, respectively. 2. The weights of pituitary gland from hatching to 22 weeks of age at all observation weeks were not recognised significantly among the compared groups except 4, 14 and 16 weeks of age. 3. Correlations between week of age, body weight, testis, comb and pituitary gland, in the course of 22 weeks, were highly significant. 4. The diameters of lumina and tubules in the seminiferous tubules increased very slowly until 10 weeks of age. They showed the most marked increase at 12 weeks of age in the self-feeding groups and at 14 weeks of age in the limited feeding groups, and then continuously increased until 32 weeks of. age. 5. Primary spermatocytes appeared at first at 8 weeks in the all treatment groups, Secondary spermatocytes appeared at first at 10 weeks in the self-feeding groups and at 12 weeks in the limited feeding groups. At 14 weeks of age spermatids and spermatozoa were found at first in the self-feeding groups but spermatids were found in the limited feeding groups. 6. Age of the first ejaculation was between 14 and 16 weeks of age in the all treatment groups. The Average semen. volume and sperm concentration ranged from 0.1-0.2$m\ell$/ ejaculate and 5.6-9.8${\times}$10$\^$8/ sperm/$m\ell$ at the age of the first ejaculation but 0.30-0.35$m\ell$/ ejaculate and 22.4-42.7${\times}$10$\^$8/ sperm int at the 20 weeks of age in the all treatment groups.

• Korean Journal of Veterinary Research
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• v.36 no.1
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• pp.151-159
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• 1996

This study was carried out to evaluate the effects of all-trans retinoic acid(RA) on the development of cholangiocarcinoma in hamsters. Eighty six female Syrian golden hamsters were divided into four groups. Group I was for the induction of the cholangiocarcinoma, which was infected orally with C sinensis and given dimethylnitrosamine(DMN, 15ppm) in drinking water for 4 weeks. Group II was for evaluating the effect of all-trans RA treatment on the cholangiocarcinogenesis, which was treated the same as group I and orally given RA(1mg/kg, 5 times per week) for 15 weeks. Group III was given only RA hr 15 weeks. Control group IV was given only soybean oil which was solvent for RA treatment. More than 5 heads of hamsters in each group were sacrificed at 4, 7, 11 and 15 weeks after the begining of the experiment. The livers were examined grossly, histopathologically, and immunohistochemically. The results obtained were as follows : 1. Death of animals started from the 11 weeks after the begining of the experiment. One of the total 22 animals(5%) and 7 of the total 24 animals(29%) died in group I and group II, respectively. 2. Proliferation of oval cell was peaked at 11 weeks in group I and at 7 weeks in group II, and decreased gradually after those periods of the time. 3. Cholangiocarcinomas were found in 1 of 6 animals(17%) at 11 weeks and in 4 of 6 animals(67%) at 15 weeks in group I, respectively. But in group II, the cholangiocarcinomas occured in 1 of 5 animals(20%) at 7 weeks, in 7 of 12 animals(58%) at 11 weeks and in 2 of the rest animals(100%) at 15 weeks, respectively. 4. Expression of $\alpha$-fetoprotein(AFP) of the oval cells in the group II showed the same degree of positive reaction at that of group I at 4 weeks. But AFP postive oval cells decreased gradually and AFP negative oval cells(ductlike oval cells) increased gradually. 5. Expression of cytokeratin of the oval cells in group II was shown slightly at 4 weeks and the degree of expression increased moderately from the 7 weeks. But the expression of the oval cells in group I was shown slightly after the 7 weeks. These results suggested that all-trans RA promoted the occurrence and the rate of cholangiocarcinoma by inducing differentiation of small cells and oval cells in the liver of hamsters infected with C sinensis and treated with DMN.

• The Korean Journal of Food And Nutrition
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• v.5 no.2
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• pp.90-98
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• 1992

This study was divised to observe the effects of defatted(by petroleum ether) Korean ginseng on the cholesterol level of Sprague-Dowley Albino male rats by alternating the diet. 130 heads of weaned rats having 83$\pm$4g of body weight were fed with each stock diets supplemented with 0.5, 1.0 and 3.0% defatted ginseng powder for 4 or 8 weeks, and after that fed with stock diet only for 8 or 4 weeks. Total cholesterol and free form cholesterol contents in serum, liver and aorta of them were determined, and compared with the each corresponding group which was fed with defatted ginseng control diet for 12 weeks. Total cholesterol and free form cholesterol contents in the serum were increased caused by the alternating diets which was fed on 0.5, 1.0 and 3.0% defatted ginseng diet for 4 and 8 weeks after being fed on stock diet for 8 and 4 weeks, conversely total cholesterol contents in the aorta were decreased by the same alternating diets. Free form cholesterol contents in the serum, liver and aorta of the group which was fed on 1.0% defatted ginseng diet 8 weeks after being fed on stock diet for 4 weeks were increased, but that of the group which was fed alternately on 3.0% defatted ginseng diet were decreased than the corresponding defatted ginseng control diet group.

• Journal of Periodontal and Implant Science
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• v.24 no.2
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• pp.340-356
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• 1994

The purpose of this study was to assess the clinical and microbiological effect of chlorhexidine rinse and supragingival plaque control following scaling and root planing on adult periodontal disease. 14 patients with adult periodontitis were selected for the study . They had not taken antibiotics for 6 months and history of dental treatment for 6 months before the study. Patients received a supragingival scaling and root planing under local anesthesia, plaque control group was subjected to professional plaque control 2 times for a period 2 week, chlorhexidine rinse group were subjected to twice daily 0.2% chlorhexidine rinse for a period 2 week. Clinical examination (plaque index, gingival index, probing pocket depth) and distribution of the bacteria morphology of subgingival plaque were monitored on baseline (0 week), 1 week, 2 week, 4 week and 6 week. The results were as follows : 1. Plaque index in chlorhexidine rinse group , plaque control group and control group was significantly reduced during all weeks (P<0.05). 2. Probing pocket depth was significantly reduced at 2, 4, 6 week (P<0.05) in chlorhexidine rinse group and control group, plaque control group was significantly reduced during all weeks (P<0.05). 3. Gingival index was significantly improved at 2, 4, 6 weeks(P<0.05) in chlorhexidine group and plaque control group, control group was significantly improved at 1, 2, 4 weeks (P<0.05). 4. Percentage of cocci was significantly increased at 1, 2, 4 and 6 weeks in chlorhexidine rinse group and control group, plaque control group was significantly increased at 2, 4 and 6 weeks(P<0.05). 5. Percentage of non-motile rods in all group were not significantly changed when compared with those of baseline (0 week) (P<0.05). 6. Percentage of motile rods was significantly reduced during all weeks (P<0.05) in chlorhexidine rinse group, plaque control group was significantly reduced at 2, 4, 6 weeks and 1, 2 and 4 weeks in control group. 7. Percentage of spirochetes was significantly reduced during all weeks (P<0.05), plaque control group was significantly reduced at 2, 4, 6 weeks and 1, 2, 4 weeks in control group. This results were suggested that clinical and microbiological effect of chlorhexidine rinse and supragingival plaque control following scaling and root planing on periodontal disease

• The Journal of Pediatrics of Korean Medicine
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• v.15 no.2
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• pp.31-41
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• 2001

We studied 100 neonates to enter a Dongguk University Oriental Hospital Postpartum Care Center, during 9 months from February 10. 2001 to November 4. 2001. The conclusion is following. 1. Newborn sex ratio was 1.70. 2. Delivery method : Normal vaginal delivery was 66 and cesarean section was 34. 3. Gestation age : Premature infants less than 37 weeks were 2 term infants from 37 to 41 weeks were 98 and post-term infants 42 or more weeks were zero. 4. Period between birth and admission : First to fifth day was 66 sixth to tenth day was 32 and eleventh or more day was 2. 5. Period of admission : 1 to 7 days were 8. 8 to 14 days were 65. 15 to 21 days were 23. and 22 to 28 days were 4. 6. Weight : Birth weight less than 2500g was 3. 2500 to 3999g was 92. and 4000g or more was 5. 7. Height : Zero week after birth the average height was 48.8cm, one week after birth was 50.0cm, two weeks after birth was 51.8cm, three weeks after birth was 53.2cm, four weeks after birth was 54.5cm. 8. Head circumference : Zero week after birth the average head circumference was 34.6cm, one week after birth was 35.3cm, two weeks after birth was 35.7cm, three weeks after birth was 36.3cm, four weeks after birth was 36.8cm. 9. Chest circumference : Zero week after birth the average chest circumference was 33.2cm, one week after birth was 33.5cm, two weeks after birth was 34.4cm, three weeks after birth was 35.1cm, four weeks after birth was 36.6cm. 10. Feeding : There was not breast feeding, artificial feeding was 8, and mixing feeding was 92. 11. Jaundice : Physiologic jaundice was 10, pathologic jaundice was 1.

• Journal of Animal Environmental Science
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• v.6 no.2
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• pp.91-96
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• 2000

This study was carried out to determine the effect of sound stimulation on growth performance, feeding behaviour and egg production of laying hens. A total of 180 laying hens(4 weeks old) were alloted to 18 cages with 10hens per cage and 6 cages per treatment. Laying hens were exposed to three sounds: control, Leq 50dB and Leq 75dB. The growth performance was measured fro m4 weeks to 17 weeks of age, feeding behaviour was observed at 5weeks, 7weeks, 10weeks and 50 weeks of age using data from real-time videotapes, while eg production was recorded from 20 weeks to 50 weeks of age. Growth performance was improved in the sound stimulated laying hens from 12 weeks to 17 weeks of age. In the 50dB simulated laying hens spent more longer time for feeding than others during the experimental period. Egg production of 50dB stimulated laying hens from 20 weeks to 50 weeks was higher than others, however 75dB stimulated laying hens were significantly lower than 50dB stimulated hens(P<0.05). The results indicated that the growth and egg production of egg type chicken can be influenced by sound stimulation through physiological rhythm.

• Development and Reproduction
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• v.18 no.3
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• pp.145-152
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• 2014

This study was performed to investigate the effect of of transdermal testosterone gel (TTG) on controlled ovarian stimulation (COS) and IVF outcomes and ovarian morphology according to pretreatment duration in poor responders. A total of 120 women were recruited for this pilot study. They were randomized into control, 2 weeks, 3 weeks or 4 weeks TTG treatment groups. For three TTG treatment groups, 12.5 mg TTG was applied daily for 2 weeks, 3 weeks or 4 weeks in preceding period of study stimulation cycle. After 3 weeks of TTG pretreatment, significant increase of antral follicle count (AFC) and significant decreases of mean follicular diameter (MFD) and resistance index (RI) value of ovarian stromal artery were observed (p=0.026, p<0.001, p<0.01, respectively). The total dose of rhFSH administered for COS significantly decreased after 3 and 4 weeks TTG treatment both compared with control group (p<0.001, p<0.001). The numbers of oocytes retrieved and mature oocytes were significanty higher in 3 and 4 weeks TTG treatment groups than control group (p<0.001, p<0.001 in the number of oocytes retrieved; p<0.001, p<0.001 in the number of mature oocytes). The clinical pregnancy rate and live birth rate were increased only in 4 weeks TTG treatment group compared with control group (p=0.030 and p=0.042, respectively). These data demonstrated that TTG pretreatment for 3 to 4 weeks increases AFC and ovarian stromal blood flow, thereby potentially improving the ovarian response to COS and IVF outcome in poor responders undergoing IVF/ICSI.