• 대한약리학회지
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• 제19권1호
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• pp.61-69
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• 1983

Hypothermia is an essential preparatory procedure for cardiac surgery, which lows the metabolic rate and myocardial oxygen demand. However, hypothermia itself is a stress enough to change the tonus of sympathoadrenal system, especially the cardiovascular responses to the catecholamines. It is reported that the positive chronotropic and inotropic response of catecholamines is exaggerated during hypothermia because of decreased norepinephrine uptake at the junctional cleft or decreased catecholamine metabolism. On the other hand, there are evidences of diminished catecholamines responses in low temperature ana further, interconversion of adrenergic receptors is also suggested. Present investigation was planned to observe the cardiovascular changes and its responses to catecholamines during surface hypothermia in cat. Healthy mongrel cats, weighing $2{\sim}3\;kg$, anesthetized with secobarbital(30 mg/kg), were permitted to hypothermia by external cooling technic. Esophageal temperature, ECG (lead II), heart rate, left ventricular pressure with dP/dt, carotid artery pressure and left ventricular contractile force were monitored with Polygragh (Model 7, Grass), and the respiration was maintained with artificial respirator (V 5 KG, Narco). Followings are summarized results. 1) Surface cooling caused progressive decrease of body temperature and reached $l8.8{\pm}0.8^{\circ}C$ and $16.9{\pm}0.6^{\circ}C$ in 120 and 150 min respectively, after immersion into ice water, and ventricular fibrillation was developed at $20.4{\pm}0.65^{\circ}C$. 2) Heart rate, blood pressure and myocardial contractility were decreased after initial increase as the body temperature falls. 3) Systolic and diastolicdd P/dt of left ventricular pressure were decreased and that the decrement of diastolic dP/dt was more marked. 4) On ECG, ST depression, Twave inversion and prolongation of PR interval were prominent in hypothermia, and moreover, the prolongation of PR interval was marked just prior to the development of ventricular fibrillation. 5) The cardiovascular responses to catecholamines, especially to isoproterenol, were suppressed under hypothermia.

• Tribology and Lubricants
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• 제36권5호
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• pp.267-273
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• 2020

This study experimentally investigates hydrophobic surfaces fabricated via additive manufacturing. Additive manufacturing, commonly known as 3D printing, is the process of joining materials to fabricate parts from 3D model data, usually in a layer-upon-layer manner. Digital light processing is used to fabricate hydrophobic surfaces in this study. This method uses photo-curable resins and ultraviolet (UV) sources. Moreover, this technique generally has faster shaping speeds and is advantageous for the fabrication of small components because it enables the fabrication of one layer at a time. Two photo-curable resins with different compositions are used to fabricate micro-patterns of hydrophobic surfaces. The resins are composed of a photo-initiator, monomer, and oligomer. Experiments are conducted to determine suitable process conditions for the fabrication of hydrophobic surfaces depending on the type of resin. The most important factors affecting the process conditions are the UV exposure time and slice thickness. The fabrication capability according to the process conditions is evaluated using the side and top views of the micro-patterns observed using a microscope. The micro-patterns are collapsed and intertwined when the exposure time is short because sufficient light (heat) is not applied to cure the photo-curable resin with a given slice thickness. On the other hand, the micro-patterns are attached to each other when the exposure time is prolonged because the over-curing time can cure the periphery of a given shape. When the slice is thicker, the additional curing area is enlarged in each slice owing to the straightness of UV light, and the slice surface becomes rough.

• International Journal of Concrete Structures and Materials
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• 제11권1호
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• pp.135-149
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• 2017

The prediction of the actual ultimate capacity of confined concrete columns requires partial confinement utilization under eccentric loading. This is attributed to the reduction in compression zone compared to columns under pure axial compression. Modern codes and standards are introducing the need to perform extreme event analysis under static loads. There has been a number of studies that focused on the analysis and testing of concentric columns. On the other hand, the augmentation of compressive strength due to partial confinement has not been treated before. The higher eccentricity causes smaller confined concrete region in compression yielding smaller increase in strength of concrete. Accordingly, the ultimate eccentric confined strength is gradually reduced from the fully confined value $f_{cc}$ (at zero eccentricity) to the unconfined value $f^{\prime}_c$ (at infinite eccentricity) as a function of the ratio of compression area to total area of each eccentricity. This approach is used to implement an adaptive Mander model for analyzing eccentrically loaded columns. Generalization of the 3D moment of area approach is implemented based on proportional loading, fiber model and the secant stiffness approach, in an incremental-iterative numerical procedure to achieve the equilibrium path of $P-{\varepsilon}$ and $M-{\varphi}$ response up to failure. This numerical analysis is adapted to assess the confining effect in rectangular columns confined with conventional lateral steel. This analysis is validated against experimental data found in the literature showing good correlation to the partial confinement model while rendering the full confinement treatment unsafe.

• 벤처창업연구
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• 제2권4호
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• pp.71-102
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• 2007

기존의 많은 연구에서는 R&D 투자를 포함한 기술진보 요인이 TFP의 결정요인으로 작용한다는 실증연구는 많았으나, 산업 분석에 있어서 규모의 경제가 TFP에 미치는 영향에 대한 실증분석이 많지 않고 또 이들 연구들의 대부분이 비모수적 멤퀴스트 생산성지수 분석이나 확률적 변경생산함수 모형을 사용함으로써 개별 독립변수가 TFP에 미치는 영향에 대한 실증분석이 이루어지지 않았다. 따라서 본 연구에서는 기존의 성장회계방정식 요인 분해를 통해 산업별 TFP 증가율을 도출하고, 산업별 TFP의 영향 요인으로 R&D 투자와 규모의 경제(산업별 영세성)를 고려한 실증분석 모델을 구축하여 TFP 결정요인에 대해 실증 분석하였다. 우선 전체 15개 산업 기준 TFP 증가율을 보면 1993${\sim}$1997년 연평균 약 3.8%에 불과했으나, 외환위기 이후 1999${\sim}$2000년 연평균 7.8%로 상승하였다. 한편 1993${\sim}$2000년 사이의 산업별 TFP 연평균 증가율을 보면 IT 제조업 부문인 전기전자기기제조 부문이 11.6%로 가장 높게 나타났으며, 가구 및 기타 제품 제조는 -0.4%를 나타냈다. 서비스산업의 경우에는 운수 창고 통신 부문이 7.3%로 전기 수도 가스 2.9%, 도소매 음식 숙박-3.7%보다 훨씬 높은 TFP 증가율을 보였다. TFP의 결정요인에 대한 실증분석 결과, R&D와 TFP와의 상관관계는 전반적으로는 유의성이 검증되지 않은 정(+)의 상관관계로 나타났으나, 전체 종사자 중 자영업주 및 무급가족 종사자수를 산업별 영세성을 나타내는 대리변수로 사용한 모델에서의 유의한 부(-)의 상관관계를 보였다. 한편 산업별 고유의 규모의 영세도를 대리하는 변수들의 추정 계수의 부호는 일관되게 한 산업의 규모의 영세도가 높을수록 그 산업의 TFP 증가율이 낮아짐을 나타내는 결과를 얻을 수 있었다.

• Journal of Animal Science and Technology
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• 제52권6호
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• pp.475-480
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• 2010

The bovine fatty acid binding protein 4 (FABP4) plays an important role to uptake intracellular fatty acid. It has been previously reported as a positional candidate gene for marbling score in livestock. The re-sequencing of FABP4 gene detected a polymorphic AT repeated sequence in intron II of FABP4 gene. Allelic distribution for this microsatellite marker was examined in other cattle breeds. A total of 8 alleles were detected with diverse repeat units (14 to 21 AT repeat) in Hanwoo and 7 breeds. Of the 8 alleles, the predominant alleles were $[AT]_{16}$, $[AT]_{18}$ and $[AT]_{19}$ in the Hanwoo and 7 cattle breeds. The linear mixed model for genotypic effect (3237AT) on carcass traits showed a significant effect on marbling score (MAR P=0.025) and live weight (LWT; P=0.04) in the 583 Hanwoo cattle population. Live weight (LW) was highest in the homozygous $(AT)_{17}$ genotype ($557.5{\pm}6.94$) and lowest in the heterozygous $(AT)_{16/17}$ genotype ($521.7{\pm}7.70$). On the other hand, the homozygous $(AT)_{17}$ genotype ($3.0{\pm}0.15$) has the highest effect on marbling score and the lowest effect was in homozygous (AT)$_{18}$ genotype ($2.2{\pm}0.15$). The marbling score difference between both groups was 0.8 which is around two times higher than SNP genotype effect on marbling score in Limousin $\times$ Wagyu crosses.

• 대한의용생체공학회:의공학회지
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• 제28권4호
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• pp.549-555
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• 2007

In order to study cortical properties in human, it is necessary to obtain an accurate and explicit representation of the cortical surface in individual subjects. Among many approaches, surface-based method that reconstructs a 3-D model from contour lines on cross-section images is widely used. In general, however, medical brain imaging has some problems such as the complexity of the images, non-linear gain artifacts and so on. Due these limitations, therefore, extracting anatomical structures from imaging data is very a complicated and time-consuming task. In this paper, we present an improved method for extracting contour lines of cortical surface from magnetic resonance images that simplifies procedures of a conventional method. The conventional method obtains contour lines through thinning and chain code process. On the other hand, the proposed method can extract contour lines from comparison between boundary data and labeling image without supplementary processes. The usefulness of the proposed method has been verified using brain image.

• 한국수학사학회지
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• 제17권3호
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• pp.109-120
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• 2004

이 연구는 학과 과제와 기말 프로젝트에 있는 문제들 중에서 컴퓨터를 활용하여 수학적 문제 해결을 해 가는 세 명의 예비 교사를 연구 조사하였다 모든 연구 참여자들의 활동과 컴퓨터를 활용한 문제 해결 과정을 관찰하고 촬영하였다. 가능한 경우 예비 교사들의 탐구활동 전과 후 및 탐구활동 중에 개별적인 면담을 하였다. 자료수집 방법은 관찰, 면담, 현장 기록, 제출과제, 컴퓨터 작업, 오디오와 비디오 테이프를 사용하였다. 수학적 문제 해결 초기 단계에서는, 모든 연구 참여자들이 그래프와 데이터를 사용하여 모델 만들기, 사인 함수의 일반적 개념에 대하여 절차적 지식과 개념적 지식이 약하게 형성되어 있었으나 컴퓨터를 활용한 수학적 문제 해결 활동을 통하여 그들은 절차적 지식과 개념적 지식을 강하게 구성하였고 그들을 적절하게 연계시킬 수 있었다

• 한국진공학회지
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• 제7권4호
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• pp.293-299
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• 1998

Cu가 흡착된 Si(100)2$\times$1 표면의 원자구조와 전자구조를 연구하기 위해 기판온도와 증착량을 변화시키면서 각 조건에 대해서 LEED 패턴과 수직방향($\theta e=0^{\circ}$)UPS스펙트럼을 분석했다. UPS스펙트럼들에는 상온증착했을 때 1.3ML 이하 증착량에서 실리사이드와 관련 된 전자구조가 약하게 나타났고, 증착량을 증가시킴에 따라 Cu 3d 밴드의 세기가 급격히 증가하였다. 실리사이드 형성을 나타내는 전자구조는 상온증착 후 $300^{\circ}C$이상 열처리 하거나 기판온도 $400^{\circ}C$에서 증착했을 때 더욱 뚜렷이 구분되어 관찰 되었다. 이 전자구조들은 실리 사이드의 유리 및 탈착온도인 $750^{\circ}C$로 열처리 했을 때 사라졌다. 특히, 기판온도 $400^{\circ}C$에서 증착하면 낮은 증착량에서는 페르미 준위를 지나는 표면상태 피크가 관측되었다. Rigid band model에 따르면 이 피크는 표면의 비어있는 전자상태(surface empty state)에 Cu의 4s1전자가 채워지면서 생기는 것으로 여겨진다. LEED패턴 관찰에서는 상온증착 및 상온증 착 후 열처리 했을 때 Cu에 의한 초격자상은 관찰되지 않았지만, 기판의 온도를 변화시키면 서 증착하였 때 기판온도에 따라 Cu에 의한 여러 가지 초격자상이 관찰되었다. 즉, $400^{\circ}C$에 서 1.5ML증착하면 청정표면 2$\times$+2$\times$2, $450^{\circ}C$에서 0.5ML증착하면 청정표면 2$\times$+5$\times$1, $450^{\circ}C$ 에서 3ML증착하면 청정표면 2$\times$1+2$\times$2+5$\times$5+10$\times$2등 LEED패턴을 관찰할 수 있었다.

• 대한치과보철학회지
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• 제33권2호
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• pp.335-353
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• 1995

The purpose of this study was to the determine the optimal torques values to tighten the retaining screw. 3-different implant system tested were as follows : Branemark implant system$(3.75mmD{\times}100mm)$, Steri-Oss implant system$(3.8mmD{\times}10mm)$. One fixtures of each implant system was mounted into the epoxy resin block and abutment/superstructure complex was constructed. Eighty dental college students(male : 40, female : 40) of Chosun University were selected and were asked to tighten the retaining screws. Abutment/superstructure complex of each implant system was tightened to the maximum torque by use of hand-held screw driver, and then torque value was measured with torque value was measured with torque driver(Tohnichi torque driver, model 20 FTD, Tohnichi MFG, Co., LTD., Tokyo, Japan). Abutment/superstructure complex of each implant system was titghtened to each torque of 10 N-cm, 20 N-cm and 30 N-cm, and then the dynamic load(vertical & diagonal load) was applied to the abutment / superstructure complex. The gap between abutment/superstrure in each implant system was measured with 3-dimensional measuring microscope(model No. 850, Germany). The results were as follow : 1. Torque values according to the individual subjects showed wide range. 2. Torque values according to sex showed statistical significant difference. Those are as follows : in case of male, $9.38{\pm}2.93$ N-cm ; incase of female, $7.80{\pm}2.25$ N-cm. 3. Torque values according t implant systems showed statistical significant difference. Those are as follows : in ase of Branemark implant system, $6.54{\pm}1.54$ N-cm : in ase of Steri-Oss implant system, $10.1{\pm}2.88$ N-cm ; in case of IMZ implant system, $9.18{\pm}2.17$ N-cm. 4. The more torque value of tightening screw was increased, the less the gap was after the vertical and diagonal loading. 5. The gap after the diagonal loading was greater than that after the vertical loading. 6. The magnitude of gap between abutment/superstructure in order of IMZ, Steri-Oss, Branemark implant system after the verical and diagonal loading. 7. The gap under the diagonal loading after applying 30 N-cm torque showed no statistical significant difference in cases of the Branemark system and the Steri-Oss implant system but it showed significant different in case of the IMZ implant system.

• 한국음향학회지
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• 제38권2호
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• pp.184-192
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• 2019

33-모드 링은 31-모드 링에 비하여 결합상수와 압전상수 d가 높기 때문에 광대역 수중 음향 트랜스듀서로 활용성이 높다. 반면 31-모드 링은 축대칭 구조이므로 수치해석 수행시 2차원 축대칭 모델로 간략히 해석이 가능하지만, 33-모드 링은 3차원 수치해석을 수행해야 한다. 즉, 특성 예측을 위해 많은 전산자원과 계산시간이 소요된다. 따라서 33-모드 링의 전기-기계-음향 응답을 모사할 수 있는 등가의 31-모드 링의 유효 물성을 도출할 수 있다면 소나 트랜스듀서 설계 등에 실용적일 것이다. 본 연구에서는 응답 특성을 모사하기 위해 각 링의 전기, 기계 임피던스 및 변환계수(${\phi}$)가 동일하다고 가정하여 등가 31-모드 링의 유효 밀도(${\rho}_{31_{-}eff}$), 컴플라이언스($s^E_{11_{-}eff}$), 압전 상수($d_{31_{-}eff}$), 유전 상수(${\varepsilon}^T_{33_{-}eff}$)를 유도했다. 도출한 유효 물성을 이용하여 진공상태의 링, 수중에서 공기 배킹의 링, 그리고 수중에서 링 내부에 자유롭게 유체가 드나드는 링에 대하여 수치해석을 하였고 이를 33-모드 링의 응답특성과 비교하였다.