• 한국정보통신설비학회:학술대회논문집
• /
• 한국정보통신설비학회 2007년도 학술대회
• /
• pp.386-389
• /
• 2007

TV technology started from black and white TV. Color TV invented and users request more realistic TV technology. The next technology is 3DTV. For 3DTV, 3D display technology, 3D coding technology, digital mux/demux technology in broadcast and 3D video acquisition are needed. Moreover, Almost every contents now exist are 2D contents. It causes necessity to convert from 2D to 3D. This article describes 2D/3D conversion algorithm and H/W platform on FPGA board. Time difference makes 3D effect and convolution filter increased the effect. Distorted image and original image give 3D effect. The algorithm is shown on 3D display. The display device shows 3D effect by parallax barrier method and has FPGA board.

• 한국HCI학회논문지
• /
• 제7권1호
• /
• pp.1-10
• /
• 2012

본 연구는 3D 상영관 내의 각 좌석의 공간적 특징에 따라 3D 효과가 어떻게 나타나는지를 시각피로도, 프레즌스, 인지된 특징을 통해 살펴보았다. 연구결과 극장 좌석의 위치가 스크린으로부터 떨어진 거리와 시야각이 시각피로도와 인지된 특성에 유의미한 영향이 있음을 검증하였다. 연구 결과는 다음과 같다. 첫째, 좌석별 시각피로도와 스크린으로부터의 거리 평균지점으로 부터의 편차와 시야각은 정적 상관관계가 있었다는 점에서 3D 상영관에서 3D 품질을 보장하기 위한 좌석 배치에 유의해야 함을 알려준다. 둘째, 3D 상영관에서 좌석의 위치적 영향이 프레즌스에는 나타나지 않았다. 셋째, 좌석별 인지된 특성과 스크린으로부터의 거리 평균지점으로 부터의 편차와 시야각은 부적 상관관계가 있었다는 점에서 3D 상영관의 모든 좌석에서 3D에 대한 인지된 특성이 다르다는 것을 알 수 있다. 본 연구는 3D극장에서의 실증적인 연구를 통해 공간적 변인에 따른 3D효과를 검증했으며, 연구 결과는 3D극장 좌석의 표준을 제정하기 위한 기초자료로 삼을 수 있다. 또한 3D 영상의 성능지표 및 피로도 규제와 관련한 법 제정에 도움이 될 수 있을 것이다.

• JSTS:Journal of Semiconductor Technology and Science
• /
• 제12권2호
• /
• pp.139-149
• /
• 2012

A 3D stacked IC is made by multiple dies (possibly) with heterogeneous process technologies. Therefore, die-to-die variation in 2D chips renders on-package variation (OPV) in a 3D chip. In spite of the different variation effect in 3D chips, generally, 3D die stacking can produce high yield due to the smaller individual die area and the averaging effect of variation on data path. However, 3D clock network can experience unintended huge clock skew due to the different clock propagation routes on multiple stacked dies. In this paper, we analyze the on-package variation effect on 3D clock networks and show the necessity of a post silicon management method such as body biasing technique for the OPV induced 3D clock skew control in 3D stacked IC designs. Then, we present a parametric yield improvement method to mitigate the OPV induced 3D clock skew.

• 한국콘텐츠학회논문지
• /
• 제13권2호
• /
• pp.198-210
• /
• 2013

삼차원 입체 영상으로 TV 프로그램을 시청할 때 나타날 수 있는 콘텐츠의 영향을 살펴보았다. 여러 나라에서 삼차원 영상 산업을 일으키기 위한 방법으로 성인물을 사용하고 있기 때문에 선정적인 콘텐츠의 영향을 우선적으로 살펴보았다. 동일한 콘텐츠일지라도 영상의 재현 방식(2D와 3D)의 차이에 따라 시청자 경험이 달라지는지를 살펴보기 위해 영상 시청 후 실재감과 각성, 성적 태도의 변화를 관찰하였다. 실험 결과 삼차원 입체 영상을 본 참가자는 이차원 영상으로 시청한 참가자에 비해 영상의 실재감을 더 높게 지각하였으며, 보수적인 성적 태도를 가지는 경향성을 보였다. 이 결과는 삼차원 영상의 입체감이 선정적인 콘텐츠의 지각과 수용에 영향을 줄 수 있다는 것을 의미한다. 이 연구 결과는 3D TV 방송의 시청 안정성을 위한 권고안을 제작하는데 도움을 줄 수 있을 것이다.

• Oncology Letters
• /
• 제18권5호
• /
• pp.4858-4864
• /
• 2019

XAV939, a tankyrase inhibitor, exerts an anticancer effect in 3-dimensional (3D) cultured SW480 cells, however this is not exhibited in 2-dimensional (2D) cultured SW480 cells. In the current study, XAV939 induced a 3.7-fold increase in cellular apoptosis in 3D culture but not in the 2D culture. However, no significant changes were indicated in cell cycle distribution in the 2D or 3D culture. Based on the observation that protein expression, which was associated with the glycolytic pathway, was increased in the 3D culture, the effect of XAV939 on the patterns of glycolytic protein expression was assessed. XAV939 was revealed to decrease lactose dehydrogenase A (LDHA) expression in 3D cultured SW480 cells, but only exerted a small effect in the 2D culture. The coadministration of XAV939 with the LDHA inhibitor FX11 decreased proliferation in 3D cultured SW480 cells compared with the single administration of FX11, while there was no additive effect in the 2D culture. The lactate assay also indicated that XAV939 decreased lactate secretion in the 3D cell culture but not in the 2D culture. These results suggest that XAV939 exerts an anticancer effect through inhibition of LDHA in the 3D culture.

• 대한화장품학회:학술대회논문집
• /
• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
• /
• pp.700-718
• /
• 2003

Fructan, a polysaccharide existing in plants or produced by microorganisms, is a sugar polymer of fructose with $\beta$-2,6 linkages. In this study, we investigated some cosmeceutical properties of Fructan such as moisturizing effect, cell proliferation effect, anti-inflammation effect and cell cytotoxicity. Zymomonas mobilis, a microorganism producing Fructan, was cultured in a medium containing 10％ sucrose and 2％ yeast extract as main components for 24 hours at 37$^{\circ}C$ and pH 7. Fructan was obtained by precipitation from the cultured medium by adding alcohol (alcohol ratio of 1:3) after removing the enzyme by centrifuging. Fructan exhibited almost same moisturizing effect as hyaluronic acid and cell proliferation effect on human fibroblast and keratinocyte as well. Moreover, on cell proliferation test on bio-artificial skin constructed by 3-dimensional(3-D) culture after inducing primary skin inflammation with 0.5％ sodium lauryl sulfate (SLS), the 3-D artificial skin treated with 0.01 mg/ml, 0.05mg/ml of Fructan exhibited higher cell proliferation than the 3-D artificial skin treated with SLS only. On anti-inflammation test on 3-D artificial skin evaluated by measuring secreted quantity of interleukin-1$\alpha$ (IL-1$\alpha$) which is a pre-inflammatory mediator induced by SLS, the quantity of IL-1$\alpha$on the 3-D artificial skin treated with 0.01 mg/ml, 0.05mg/ml of Fructan was less than the one on the 3-D artificial skin treated with SLS only. As a result of these studies, Fructan has anti-inflammation effect against inflammatory reaction by a skin irritant as well as cell proliferation effect in bio-artificial skin. Fructan was also evaluated as a safe material without any toxicity in safety tests using fibroblasts and animals.

• 한국정보통신학회논문지
• /
• 제26권5호
• /
• pp.682-687
• /
• 2022

터널링 전계효과 트랜지스터(tunneling field-effect transistor; TFET)로 적층된 3차원 적층형 집적회로(monolithic 3D integrated-circuit; M3DIC)에 대한 연구 결과를 소개한다. TFET는 MOSFET(metal-oxide-semiconductor field-effect transistor)와 달리 소스와 드레인이 비대칭 구조이므로 대칭구조인 MOSFET의 레이아웃과 다르게 설계된다. 비대칭 구조로 인해서 다양한 인버터 구조 및 레이아웃이 가능하고, 그 중에서 최소 금속선 레이어를 가지는 단순한 인버터 구조를 제안한다. 비대칭 구조의 TFET를 순차적으로 적층한 논리 게이트인 NAND 게이트, NOR 게이트 등의 M3DIC의 구조와 레이아웃을 제안된 인버터 구조를 바탕으로 제안한다. 소자와 회로 시뮬레이터를 이용해서 제안된 M3D 논리게이트의 전압전달특성 결과를 조사하고 각 논리 게이트의 동작을 검증한다. M3D 논리 게이트 별 셀 면적은 2차원 평면의 논리게이트에 비해서 약 50% 감소된다.

• The Korean Journal of Physiology and Pharmacology
• /
• 제18권5호
• /
• pp.397-402
• /
• 2014

Microglia are activated by inflammatory and pathophysiological stimuli in neurodegenerative diseases, and activated microglia induce neuronal damage by releasing cytotoxic factors like nitric oxide (NO). Activated microglia synthesize a significant amount of vitamin $D_3$ in the rat brain, and vitamin $D_3$ has an inhibitory effect on activated microglia. To investigate the possible role of vitamin $D_3$ as a negative regulator of activated microglia, we examined the effect of 25-hydroxyvitamin $D_3$ on NO production of lipopolysaccharide (LPS)-stimulated microglia. Treatment with LPS increased the production of NO in primary cultured and BV2 microglial cells. Treatment with 25-hydroxyvitamin $D_3$ inhibited the generation of NO in LPS-activated primary microglia and BV2 cells. In addition to NO production, expression of 1-${\alpha}$-hydroxylase and the vitamin D receptor (VDR) was also upregulated in LPS-stimulated primary and BV2 microglia. When BV2 cells were transfected with 1-${\alpha}$-hydroxylase siRNA or VDR siRNA, the inhibitory effect of 25-hydroxyvitamin $D_3$ on activated BV2 cells was suppressed. 25-Hydroxyvitamin $D_3$ also inhibited the increased phosphorylation of p38 seen in LPS-activated BV2 cells, and this inhibition was blocked by VDR siRNA. The present study shows that 25-hydroxyvitamin $D_3$ inhibits NO production in LPS-activated microglia through the mediation of LPS-induced 1-${\alpha}$-hydroxylase. This study also shows that the inhibitory effect of 25-hydroxyvitamin $D_3$ on NO production might be exerted by inhibiting LPS-induced phosphorylation of p38 through the mediation of VDR signaling. These results suggest that vitamin $D_3$ might have an important role in the negative regulation of microglial activation.

• 기술혁신학회지
• /
• 제21권2호
• /
• pp.663-683
• /
• 2018

본 연구는 우리나라 중소기업 R&D 조세지원의 효과성을 분석하고, 중소기업 R&D 활성화를 촉진할 수 있는 조세지원제도 개선방안을 도출하고자 하였다. 이를 위하여 최근 3년간 기업별 조세감면액 자료에 고정효과 모형(Fixed Effect Model)과 확률효과 모형(Random Effect Model), 그리고 패널 음이항모형(Panel Negative Binomial Model)을 적용하여 분석을 수행하였다. 분석 결과, 동일 규모의 재정을 투입하는 경우 R&D 조세감면이 R&D 직접지원에 비해 R&D 투자 제고효과는 5.3배, 연구원 수 증가효과는 4.3배 높은 것으로 나타났다. 지역별로는 비수도권 소재 기업에서 조세감면의 효과가 직접 지원보다 높게 나타났다. 이를 바탕으로 중소기업 R&D 활성화를 위해 창업 중소기업의 미사용 R&D 세액공제액의 세금 포인트 전환, 중소기업의 R&D설비투자 비용에 대한 최저한세 적용 배제, R&D 세액공제 제도의 통합 운영 등의 개선방안을 제시하였다.

• 디지털산업정보학회논문지
• /
• 제6권3호
• /
• pp.141-149
• /
• 2010

The success of movie 'Avatar' make people be interested in 3D stereoscopic movie, and government and 3D industry acknowledge that it is another opportunity to develop 3D market since 1920s. However, despite much interest little research to evaluate the effect of 3D stereoscopic exists. The present research aimed to disclose 3D effect compared to 2D by assumption of the importance of 3D stereoscopic and little evaluation to that as well. When audience are exposed to 3D stereoscopic, many outcomes are supposed to be differentiated from when to 2D. From this hypothesis, this paper examined mood, attitude, and presence as dependent variables. Using polarized stereoscopic projection display, 30 participants watched 2D and another 30 watched 3D stereoscopic movie which were the same content. On conclusion, the two groups were not significantly different and this involved much insight.