• Title/Summary/Keyword: 3D Digital

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Effects of Apigenin on Glutamate-induced $[Ca^{2+}]_i$ Increases in Cultured Rat Hippocampal Neurons

  • Han, Ji-Hwa;Kim, Ki-Jung;Jang, Hyun-Jong;Jang, Ju-Ho;Kim, Myung-Jun;Sung, Ki-Wug;Rhie, Duck-Joo;Jo, Yang-Hyeok;Hahn, Sang-June;Lee, Mun-Yong;Yoon, Shin-Hee
    • The Korean Journal of Physiology and Pharmacology
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    • v.12 no.2
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    • pp.43-49
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    • 2008
  • Flavonoids have been shown to affect calcium signaling in neurons. However, there are no reports on the effect of apigenin on glutamate-induced calcium signaling in neurons. We investigated whether apigenin affects glutamate-induced increase of free intracellular $Ca^{2+}$ concentration ($[Ca^{2+}]_i$) in cultured rat hippocampal neurons, using fura-2-based digital calcium imaging and microfluorimetry. The hippocampal neurons were used between 10 and 13 days in culture from embryonic day 18 rats. Pretreatment of the cells with apigenin ($1{\mu}M$ to $100{\mu}M$) for 5 min inhibited glutamate ($100{\mu}M$, 1 min) induced $[Ca^{2+}]_i$ increase, concentration-dependently. Pretreatment with apigenin ($30{\mu}M$) for 5 min significantly decreased the $[Ca^{2+}]_i$ responses induced by two ionotropic glutamate receptor agonists, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic (AMPA, $10{\mu}M$, 1 min) and N-methyl-D-aspartate (NMDA, $100{\mu}M$, 1 min), and significantly inhibited the AMPA-induced peak currents. Treatment with apigenin also significantly inhibited the $[Ca^{2+}]_i$ response induced by 50 mM KCl solution, decreased the $[Ca^{2+}]_i$ responses induced by the metabotropic glutamate receptor agonist, (S)-3,5-dihydroxy-phenylglycine (DHPG, 100 $[Ca^{2+}]_i$, 90 s), and inhibited the caffeine (10 mM, 2 min)-induced $[Ca^{2+}]_i$ responses. Furthermore, treatment with apigenin ($30{\mu}M$) significantly inhibited the amplitude and frequency of 0.1 mM $[Mg^{2+}]_o$-induced $[Ca^{2+}]_i$ spikes. These data together suggest that apigenin inhibits glutamate-induced calcium signaling in cultured rat hippocampal neurons.

Availability Analysis on Detection of Small Scale Gas Emission Facilities using Drone Imagery (드론영상을 이용한 소규모 가스 배출시설 탐지 가능성 분석)

  • Shin, Jung-Il;Kim, Ik-Jae;Hwang, Dong-Hyun;Lee, Jong-Min;Lim, Seong-Ha
    • Journal of Cadastre & Land InformatiX
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    • v.47 no.1
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    • pp.213-223
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    • 2017
  • Recently, the air quality of South Korea has deteriorated and public interest has been increasing. Various observation means are used for the monitoring of the atmospheric environment, but it relies on the experience and judgment of the observer in the absence of spatial information on the emission facilities. The purpose of this study was to determine the availability of using drones for monitoring air pollutant emission facilities. A texture transformation method was applied to the drone ortho image to detect the small gas emission facility and the slope data calculated by the digital surface model (DSM) was used to reduce the false alarm ratio. As a result, it shows the possibility of using drones in the detection of small gas emission facilities by showing about 80% of positive detection ratio and 40% of false alarm ratio. In the future, various researches are required to the improve positive detection ratio and the reduction of the false alarm ratio. Based on these results, it is necessary to construct a database including 3D spatial information of air pollutant emission facilities.

The Effects of Financial Information to the Firm Valuation for Information Technology Related Companies : Evidences from Software, Degital Content, Internet Related Companies listed in KOSDAQ (회계정보가 정보기술 관련 산업의 기업가치 평가에 미치는 영향 : 소프트웨어, 디지털콘텐츠, 인터넷 관련 코스닥 상장기업을 중심으로)

  • Kim, Jeong-Yeon
    • The Journal of Society for e-Business Studies
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    • v.17 no.3
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    • pp.73-84
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    • 2012
  • With transition to Knowledge society and introduction of information industry, there are many companies which have higher stock price than the suggested value from its financial information. To explain similar cases in capital markets, many researchers focus on non-financial information such as Web Traffic data or intangible assets such as intellectual property rights rather than traditional financial analysis. Besides, the relationships between financial and non-financial information with firm value are changed according to industry lifecycle. As Industry grows, financial information of company is more important for firm valuation in Capital market. We'd like to review the changes of relationships between financial information and firm valuation in Capital market especially for "Software", "Digital Contents", and "Internet" companies listed in Kosdaq market during 2000~2011. The result of data analysis shows the financial information gets more important after 2007. Inversely, it provides analytical bases that related industry gets mature. Also we show that intangible properties are more relevant to stock price of those technical based companies than others.

Design and Implementation of GIS-Based Mobile Management System for the Ariul DIPSDRM Method Using UML (UML을 이용한 GIS기반 새만금 DIPSDRM 공법 모바일 관리 시스템 설계 및 구현)

  • Baek, Jeong-Ho;Lee, Hong-Ro
    • Journal of the Korean Association of Geographic Information Studies
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    • v.16 no.1
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    • pp.1-14
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    • 2013
  • The world largest land reclamation project in the name of Saemangeum(Ariul) from 1991 to the present has been implementing in a part of the west coast of Korea. In the Saemangeum reclamation project, the large-scale project cost is used for the landfill reclamation. A number of landfill reclamation methods have been studied in order to reduce the large-scale cost of the Saemangeum project under construction. There are many studies related to the on-site real-time monitoring with mobile systems for operating a wide range of landfill. In order to apply the work method for efficient cost-savings in the landfill operations to the Samangeum project, this paper develops a mobile management system that is composed of a mobile interface module, a data server module for data transmission and storage, and an analysis server module to analyze the input data and derive the results. The mobile system is designed by analysing user's and system requirements, functional interactions, and data flow using unified modeling language(UML). The user interface is developed for the on-site real-time monitoring through the status and related attributes of land reclamation by using the digital maps of the Samangeum coverage via mobile devices. Finally, a mobile management system would be developed that can provide a 3D GIS service based on the Dry Internal Project Site Digging Reclamation Method(DIPSDRM).

Testimony of the Real World, Documentary-Animation (현실세계의 증언, 다큐멘터리-애니메이션 분석)

  • Oh, Jin-Hee
    • Cartoon and Animation Studies
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    • s.45
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    • pp.27-50
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    • 2016
  • The present study argues that documentary-animation films, which are based on actual human voices, on the level of representation, constitute a new expansion for the medium of animation films, which serve as testimonies to the real world. Animation films are produced using very diverse techniques so that they are complex to the degree of being indefinable, and documentary films, though based on objective representation, increase in complexity in that there exist various types of artificial interventions such as direction and digital image processing. Having emerged as a hybrid genre of the two media, documentary-animation films draw into themselves actual events and elements so that they conceptually share reality-based narratives and are visually characterized by the trappings of animation films. Generally classified as 'animated documentaries', this genre triggered discussions following the release of , a work that is mistaken as having used rotoscoping transforming live action in terms of the technique. When analyzed in detail, however, this work is presented as an ambiguous medium where the characteristics of animation films, which are virtual simulacra without reality, and of documentaries, which are based on the objective indexicality of the referents, coexist because of its mixed use of typical animation techniques, 3D programs, and live-action images. Discussed in the present study, , , and share the characteristics of the medium of documentaries in that the narratives develop as testimonies of historical figures but, at the same time, are connected to animation films because of their production techniques and direction characteristics. Consequently, this medium must be discussed as a new expansion rather than being included in the existing classification system, and such a presupposition is an indispensable process for directly facing the reality of the works and for developing discussions. Through works that directly use the interviewees' voices yet do not transcend the characteristics of animation films, the present study seeks to define documentary-animation films and to discuss the possibility of the medium, which has expanded as a testimony to the real world.

A Development of lidar data Filtering for Contour Generation (등고선 제작을 위한 라이다 데이터의 필터링 알고리즘 개발 및 적용)

  • Wie, Gwang-Jae;Kim, Eun-Young;Kang, In-Gu;Kim, Chang-Woo
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.27 no.4
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    • pp.469-476
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    • 2009
  • The new laser scanning technology allows to attain 3D information faster with higher accuracy on surface ground, vegetation and buildings of the earth surface. This acquired information can be used in many areas after modifying them appropriately by users. The contour production for accurate landform is an advanced technology that can reveal the mountain area landscapes hidden by the trees in detail. However, if extremely precise LiDAR data is used in constructing the contour, massive-sized data intricates the contour diagram and could amplify the data size inefficiently. This study illustrates the algorithm producing contour that is filtered in stages for more efficient utilization using the LiDAR contour produced by the detailed landscape data. This filtering stages allow to preserve the original landscape shape and to keep the data size small. Point Filtering determines the produced contour diagram shape and could minimize data size. Thus, in this study we compared experimentally filtered contour with the current digital map(1:5,000).

Construction of High-Resolution Topographical Map of Macro-tidal Malipo beach through Integration of Terrestrial LiDAR Measurement and MBES Survey at inter-tidal zone (대조차 만리포 해안의 지상 LiDAR와 MBES를 이용한 정밀 지형/수심 측량 및 조간대 접합을 통한 정밀 지형도 작성)

  • Shim, Jae-Seol;Kim, Jin-Ah;Kim, Seon-Jeong;Kim, Sang-Ik
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.22 no.1
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    • pp.58-66
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    • 2010
  • In this paper, we have constructed high-resolution topographical map of macro-tidal Malipo beach through integration of terrestrial LiDAR measurement and MBES survey data at inter-tidal zone. To acquire the enough information of inter-tidal zone, we have done terrestrial LiDAR measurement mounted on the roof of vehicle with DGPS through go-stop-scan method at the ebb tide and MBES depth surveying with tide gauge and eye staff measurement for tide correction and MSL calculation at the high tide all together. To integrate two kinds of data, we have unified the vertical coordination standard to Incheon MSL. The mean error of overlapped inter-tidal zone is about 2~6 cm. To verify the accuracy of terrestrial LiDAR, RTK-DGPS measurement have done simultaneously and the difference of Z value RMSE is about 4~7 cm. The resolution of Malipo topographical map is 50 cm and it has constructed to DEM (Digital Elevation Model) based on GIS. Now it has used as an input topography information for the storm-surge inundation prediction models. Also it will be possible to use monitoring of beach process through the long-term periodic measurement and GIS-based 3D spatial analysis calculating the erosion and deposition considering with the artificial beach transition and coastal environmental parameters.

A Study of the Weight value to Risky Driving Type (위험운전유형에 따른 가중치 산정에 관한 연구)

  • Oh, Ju-Taek;Lee, Sang-Yong
    • International Journal of Highway Engineering
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    • v.11 no.1
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    • pp.105-115
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    • 2009
  • According to the accident statistics published by the National Police Agency in 2007, the number of commercial vehicle(city, suburb and other buses) accidents consumes 3.5 percent of the total number of traffic accidents in this year. Since the commercial vehicles are responsible for not only the drivers but also the passengers, it leads more serious social and economic problems. There have been various forms of systems such as a digital speedometer or a black box to meet the social requirement for reducing traffic accidents and safe driving. however the system based on the data after accident control the driver by analyze dangerous drive behaviors, so there is a limit to control driver in real-time. Also speedometer currently managed provide the driver warning information in real-time, but using only the speed of vehicle and RPM information regardless of actual dangerous drive behaviors, disappear the effectiveness. In this study performed a simulation for drivers in general using a simulator programed with dangerous driving types we had developed in the previous study and judging the types. It'd be more effective system to provide the drivers warning information using weight valued in this study. However in this study is limited to apply weight as a result of simulation of drivers in general in actual situation should be made up the deficit based on information of driving type of actual commercial vehicles.

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A Study on the Characteristics and Policy Demand of the Unmanned Vehicle Industry in Gyeonggi-do (경기도 무인이동체 산업 특성과 정책수요)

  • Kim, Myung Jin
    • Journal of the Economic Geographical Society of Korea
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    • v.24 no.3
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    • pp.283-299
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    • 2021
  • As the intelligent revolution triggered by digital technology, unmanned vehicles such as self-driving cars, robots, and drones appeared, which brought about innovative changes in the industry. Gyeonggi Local government has established both an ordinance and a basic plan regarding unmanned vehicles. It is time to prepare a data-based policy by understanding the current state of the unmanned vehicle industry in the province. As a result of the survey, the unmanned vehicle industry in Gyeonggi Province is 25% of the nationwide, and more than 88% is concentrated in the southern part of Gyeonggi Province. The land sector such as the robot and autonomous vehicles are focused on 71.4% and the aviation sector such as drones are 26.7%. However, unmanned vehicle companies in Gyeonggi-do are mostly small-sized businesses with less than 10 years of experience and are in the stage of introduction and growth level. They have a plan to improve technology through continuous R&D by hiring human resources. Therefore, Gyeonggi-do needs to consider policy support for sustainable growth of start-up and small enterprises and for fostering professional manpower and technical skills as well as for establishing an unmanned vehicle industry network to create, share, and spread knowledge.

Scientific Preservation of the Relics left by the Fallen Heroes of the Korean War: Focusing on the Local Relics Kept by the Ground Operations Command (6·25전쟁 전사자 유품의 과학적 보존: 지상작전사령부 소장 지역유품 중심으로)

  • Park, Min-Seon;Oh, Seung-Jun;Lee, Ho-Yeon;Wi, Koang-Chul
    • Journal of Conservation Science
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    • v.38 no.2
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    • pp.144-153
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    • 2022
  • This study conducted scientific analysis and preservation treatment for the local 7 relics (depurator bottle, eagle patten button, rank insignia, mess tin, M1 Grand-gun cleaning tool kit, Carbine bullet, cartridge) of the fallen of Korean War excavated through the MND Agency for KIA Recovery & Identification that are possessed in the exhibition hall of the Ground Operations Command. FT-IR analysis results show that remainder of depurator bottle is assumed to play a role of water and food purifier during the war for its spectrum similar to Trisodium phosphate, and inscription carved on the cartridge that is hard to observe with naked eyes was also confirmed through 3D digital shooting method. This study also established directivity of preservation treatment of relics for stable treatment by carrying out a survey of conditions based on the microscope and visual observation. The result is expected to be used as basic data for establishment of future directivity of preservation treatment for a variety of war relics.