• The KSFM Journal of Fluid Machinery
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• v.11 no.5
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• pp.22-29
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• 2008

This study is performed to understand the effect of the variation in the passage area of a two-dimensional impeller on its performance characteristics. We observe the results with changing the area ratio of inlet to outlet about $1{\sim}2.8$. A comparison between the experimental and numerical results was performed for the same configuration in order to verify the reliability of the CFD code. Overall characteristics in the passages of impeller were analyzed in detail including streamline, Mach number, pressure and polytropic efficiency distribution. When the passage area ratio exceeds 2, the pressure ratio is high. An area ratio of 2.3 showed the highest efficiency. The results will be used as useful reference data to establish the design concept of two-dimensional impeller and to improve its performance.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.20 no.10
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• pp.3262-3271
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• 1996

Flow patterns were measured in a shrouded centrifugal impeller. The flow rate in measurements was fixed at the value corresponding to a nearly zero incidence at the blade inlet. By using a single slanted hot-wire probe and a Kiel probe mounted on the impeller hub disk, the 3-D relative velocities and the rotary stagnation pressures were measured in seven circumferential planes from the inlet to the outlet of impeller rotating at 700 rpm, and the static pressure distribution along flow passage and the slip factor at impeller outlet were calculated from the measured values. From these measured data, the primary and secondary flows, the wake production and the static pressure rise in the impeller passage were investigated. Furthermore, the secondary flow patterns and the wake's location in this impeller passage were compared with those of the unshrouded impeller.

• The Journal of Korean Medicine
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• v.25 no.1
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• pp.49-59
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• 2004

Objectives: This paper is to investigate what effects Yeonryunggobondan and Palmijihwangtang have on postponing senility in rat fibroblasts, heart-endothelial cells, mesangial cells. Methods: 1. In vitro Yeonryunggobondan and Palmijihwangtang controlled the growth of fibroblasts, heart-endothelial cells, mesangial cells, extended the PDT of them. 2. After feeding rats the drugs for 2 months, the fibroblasts, heart-endothelial cells, mesangial cells were cultured. Results: 1) In fibroblasts the PDN was incresed and the PDT was decreased at passage-1, 2 by Yeonryunggobondan and Palmijihwangtang(p<0.05). 2) In heart-endothelial cells the PDN was incresed and the PDT was decreased at passage 8 by Yeonryunggobondan and Palmijihwangtang(p<0.05). 3) In mesangial cells the PDN was increased and the PDT was decreased at passage 4 by Yeonryunggobondan, the PDN was incresed at passage 4 by Palmijihwangtang(p<0.05). Conclusions: It is concluded that both Yeonryunggobondan and Palmijihwangtang maybe be conductive to protect and delay the senescence of rat fibroblasts, heart-endothelial cells, mesangial cells.

• Journal of computational fluids engineering
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• v.8 no.3
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• pp.56-65
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• 2003

A numerical procedure for analyzing the heat transfer in a regenerative cooling passage of liquid rocket has been developed. The thermal analysis is based on the numerical model of Naraghi〔1〕. The thermodynamic and transport properties of the combustion gases are evaluated using the chemical equilibrium composition. The pressure and heat flux obtained by the isentropic relation are in good agreement with the result of Navier-Stokes equations. The effect of design parameters on heat transfer is addressed for the pressure loss and temperature variation. Also, their constraints in designing the cooling passage are recommended. Finally, in a heated rectangular duct, the effects of secondary flow on heat transfer are scrutinized by the nonlinear k- e -fu of Park et at.〔2〕.

• Transactions of the Korean Society of Automotive Engineers
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• v.12 no.3
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• pp.19-26
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• 2004

A prior fundamental study was executed using a constant volume chamber to improve the burning properties of lean pre-mixture by the injection of active radicals generated in the sub-chamber. In consequence, RI method shows remarkable progress in the aspects of burning velocity and combustible lean limit compared with SI method. In this study, the necessary additional works have been performed to be based on the former results. We changed parameters as the initial temperature and the initial pressure of mixture. And the effects of residual gas at issue in a real engine were investigated. As a result, the effects of initial temperature were significant, but on the other hand, those of initial pressure were slight. The correlation of passage hole number between overall passage hole area was grasped. And the more detailed analysis is required on residual gas.

• Journal of the Korean Society of Visualization
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• v.8 no.4
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• pp.19-25
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• 2010

The flow field measurements were conducted on the planes between impeller blades, and the gap between the impeller and turbine blades under speed ratio of 0.4. The study showed that high velocity regions move from locations near the suction surface of the impeller to the pressure blade, shroud corner as flow progresses from the mid-chord of impeller passage to exit and out into the gap region. Planes 3 through 5 also showed flow reversal occurring in the area near the shell surface and progress far into the impeller passage from the impeller passage exit, near shell surface. This affected the converter efficiency negatively. This study would aid in the construction of higher accuracy CFD models of this complex turbomachinery device.

• Journal of Embryo Transfer
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• v.27 no.3
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• pp.171-174
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• 2012

Various small molecules can be used to control major signaling pathways to enhance stemness and inhibit differentiation in murine embryonic stem cell (mESC) culture. Small molecules inhibiting the fibroblast growth factor (FGF)/ERK pathway can preserve pluripotent cells from stimulation of differentiation. In this study, we aimed to evaluate the effect of pluripotin (SC-1), an inhibitor of the FGF/ERK pathway, on the colony formation of outgrowing presumptive mESCs. After plating the zona pellucida-free blastocyst on the feeder layer, attached cell clumps was cultured with SC-1 until the endpoint of the experiment at passage 10. In this experiment, when the number of colonies was counted at passage 3, SC-1-treated group showed 3.4 fold more mESC colonies when compared with control group. However, after passage 4, there was no stimulating effect of SC-1 on the colony formation. In conclusion, SC-1 treatment can be used to promote mESC generation by increasing the number of early mESC colonies.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.29 no.3
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• pp.127-133
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• 2017

Performance analysis has been carried out on a high side scroll compressor that had a fixed scroll equipped with a circular oil groove on its thrust surface. Oil was supplied to the oil groove through an intermittent opening from a high pressure oil reservoir formed inside the orbiting scroll hub. Oil in the groove was then delivered to both suction and back pressure chambers by pressure differentials and viscous pumping action of the orbiting scroll base plate. Mathematical modeling of this oil groove system was incorporated into a main compressor performance simulation program for an optimum oil groove design. The study findings were as follows. Pressure in the oil groove can be controlled by changing its configuration and the oil passage area. With an enlarged oil passage, the pressure in the oil groove heightens due to an increased flow rate, but the pressure elevation in the back pressure chamber is small, resulting in reduced friction loss at the thrust surface between the two scrolls. On the other hand, by increasing the oil passage area, the oil content in the refrigerant flow increases. Considering all these factors, the energy efficiency ratio could be improved by about 3.6% under the ARI condition by an optimal oil groove design.

• 한국전산유체공학회:학술대회논문집
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• 1995.10a
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• pp.188-193
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• 1995

Incompressible developing entry flows through square ducts with 90 degree bends are studied numerically by using an efficient implicit SMAC scheme with different boundary conditions. This study eventually aimed at passage flow analysis of turbomachinery elements with a strong curvature such as centrifugal impeller or draft tube. The generalized implicit scheme used in the present study has been developted to solve the three-dimensional Navier-Stokes equations by the author. Numerical results for some different numerical conditions are obtained and compared with each other

• Proceedings of the KSAR Conference
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• 2001.03a
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• pp.64-64
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• 2001

To facilitate the widespread application of somatic cell cloning, improvements in blastocyst production efficiency and subsequent fetal viability are required. Area where technical improvements are needed include donor cell treatments, starvation and passage numbers. This study was carried out to investigate the effect of serum-starvation and passage on the development of ear skin fibroblast cells cloned embryos. A skin biopsy was obtained from the ear of a 2-year-old Korean Hanwoo female. The cells were cultured in 10% FBS＋DMEM up to 2-3 months(up to 10 passages) and then used. In Experiment 1, the Korean bovine Ear Skin Fibroblast cells (KbESF) were either serum starved (culture in 0.05% FBS＋DMEM) or serum fed (10% FBS＋DMEM) for 4-7 days Prior to NT In Experiment 2, the KbESF cells used for nuclear transfer in these experiments were from passages 2 to 10. The development of 208 nuclear transfer (NT) embryos reconstructed from either serum starved or serum fed ear skin fibroblast was assessed. NT embryos reconstructed from serum starved and serum fed cells showed the same developmental rate (cleavage 80.16 vs. 85.37%; blastocyst 20.63 vs. 19,51%). The development of 590 nuclear transfer (NT) embryos reconstructed from passage 2 to 10 was assessed. We observed the same developmental rates for embryos derived from later Passages as compared with those embryos from early passages(blastocyst from 16.69 to 27.91%, average 20.17%). There was no significant difference between serum-fed and serum-starved donor cells. We observed no difference in developmental rates for embryos derived from 2 to 10 passages. These data show that prolonged culture and serum starvation does not affects the cloning competence of adult somatic cells.