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Morphological changes of Schwann cells as neurotoxic responses (신경독성에 의한 Schwann 세포의 형태적 변화)

  • Rim, Byung-moo;Chae, Hyun-sok;Lee, Oh-hyung
    • Korean Journal of Veterinary Research
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    • v.34 no.4
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    • pp.801-804
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    • 1994
  • The early change observed in lead-induced neurophathy in the rat was Schwann cell swelling. In order to quantify this cell swelling, Schwann cell thickness and major diameter of the nucleus were measured using tranverse section with associated myelinated fiber of sciatic nerves. Group I rats were intoxicated with 0.5% lead acetate in the drinking water for 30 days; group II animals were treated as in group I and then restored to normal laboratory conditions for 30 days; and group III were controls. The results showed that the cell sizes were significantly greater in intoxicated animals, compared with control, and the cell sizes of group II did not differ significantly from control rats.

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A Study on the Adaptability and Cytotoxicity of Porcelain Bonded Ni-Cr Alloy (도재소부용 Ni-Cr합금의 적합성과 세포독성에 관한 연구)

  • Choi, Boo-Byung;Shin, Myung-Chull
    • The Journal of Korean Academy of Prosthodontics
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    • v.20 no.1
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    • pp.7-17
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    • 1982
  • In order to investigate the internal adaptability and cytotoxicity for porcelain fused to metal Ni-Cr alloy, two commercial alloys (Generic Gold-R alloy, Aalba Dent- Valloy)were employed and compared with new developed beryllium free Ni-Cr alloy (KIST-K alloy). After cementation of each crown to abutment die before and after ceramic bonding respectively, dies were mounted to epoxy resin and the internal space was measured between crown and die of each point on sagittal section. The results were as follows: 1) The results show that the space between the crown and the die was largest at the incisal edge, followed by the shoulder or the bevel and chamfer. The least was to be in the axial surface. 2) There were no significant difference in the adaptability of the compared alloys. 3) On day 2 of the experiment the cell multiplication was slightly inhibited by R and K alloys. However, observations taken at day 4 and 7 showed normal cell multiplication process compared to control group. 4) Alloy V exhibited the most severe cell toxicity among the alloys tested on day 2. By day 4 and 7 it showed a decrease level in toxicity, however it did not exhibit normal cell growth as compared to control group.

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Vibration Attenuation in Helicopters using an Active Trailing-edge Flap Blade

  • Natarajan, Balakumaran;Eun, WonJong;Shin, SangJoon
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2013.04a
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    • pp.347-352
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    • 2013
  • Seoul National University Flap (SNUF) blade is a small-scaled rotor blade incorporating a small trailing-edge flap control surface driven by piezoelectric actuators at higher harmonics for vibration attenuation. Initially, the blade was designed using two-dimensional cross-section analysis and a geometrically exact one-dimensional beam analysis, and material configuration was finalized. Flap deflection angle of ${\pm}45^{\circ}$ was established as the criterion for better vibration reduction performance based on an earlier simulation. Flap linkage mechanism design is carried out and static bench tests are conducted to verify the flap actuation mechanism performance. Different versions of test beds are developed and tested with the flap and chosen APA 200M piezoelectric actuators. Through significant improvements, a maximum deflection of ${\pm}3.7^{\circ}$ was achieved. High frequency experiments are conducted to evaluate the performance and transfer function of the test bed is determined experimentally. As the static tests are almost completed, rotor power required for testing the blade in whirl tower (centrifugal environment) is calculated and further preparations are under way.

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The study of dynamic safety using M&S for Integrated Electro-Mechanical Actuator installed on aircraft (M&S를 이용한 항공기용 통합형 전기식 구동장치의 동적 안전성 연구)

  • Lee, Sock-Kyu;Lee, Byoung-Ho;Lee, Jeung;Kang, Dong-Seok;Choi, Kwan-ho
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2014.10a
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    • pp.36-41
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    • 2014
  • Electro-Mechanical Actuator installed on aircraft consists of a decelerator which magnifies the torque to rotate an axis connected with aircraft control surface, a control section which controls the motor assembly through receiving orders from cockpit and a motor assembly which rotates the decelerator. EMA controls aircraft attitued, position, landing, takeoff, etc. It is important part of a aircraft. Aircraft maneuvering make vibration of EMA. Vibration may cause the vibration fatigue. For that reason, it is necessary to analyze the system safety. In this paper, first EMA is modeled in finite element method and analyzed the response from input vibration. second EMA is tested and analyzed from modal experimental data. third EMA Fe model is updated and re analyzed. and EMA is verified safety with $3{\sigma}$ stress and S/N curves.

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Hearing Status in Korean Adults according to the Fourth Korea National Health and Nutrition Examination Survey 2009 (한국 성인의 청력 상태: 국민건강영양조사 분석)

  • Kim, Ji-Su;Lee, Bong-Suk
    • Journal of Korean Public Health Nursing
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    • v.25 no.2
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    • pp.197-208
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    • 2011
  • Background: This study investigated the hearing status in Korean adults according to data from the Korea National Health and Nutrition Examination Survey 2009. Methods: The data of 3,479 adults(${\geq}20$ years, 1,492 men, 1,987 women) collected by the Korean Center for Disease Control was analyzed using ${\chi}^2$-test and logistic regression. Results: Differences in hearing loss according to individual factors were evident by follows gender, region, education status, economic status, current smoking and recognition of stress. Differences in - hearing loss according to ear related factors were evident subjective hearing status, experience of tinnitus, prevalence of chronic otitis media, and tympanomembrane abnormality. Conclusion: Hearing-related disorders can cause many social problems. This study investigated a representative cross-section of Koreans to determine the hearing status. The study was limited in that the risk factors of hearing loss were not identified. It is also recommended that a program be developed that can help control the variables identified in this study along with follow-up studies to verify the model.

Ageing assessment of zirconia implant prostheses by three different quantitative assessment techniques

  • Kyaw, Phyu Phyu;Pongprueksa, Pong;Anuchitolarn, Warangkana;Sirinukunwatta, Krongkarn;Suputtamongkol, Kallaya
    • The Journal of Advanced Prosthodontics
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    • v.11 no.5
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    • pp.253-261
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    • 2019
  • PURPOSE. To evaluate the influence of cyclic loading on phase transformation of zirconia abutments and to compare the effectiveness of three different quantitative ageing assessment techniques. MATERIALS AND METHODS. Thirty two Y-TZP prostheses fabricated from two brands, InCoris ZI and Ceramill ZI, were cemented to titanium bases and equally divided into two subgroups (n=8): control group without any treatment and aged group with cyclic loading between 20 N and 98 N for 100,000 cycles at 4 Hz in distilled water at $37^{\circ}C$. The tetragonal-to-monoclinic phase transformation was assessed by (i) conventional x-ray diffraction (XRD), (ii) micro x-ray diffraction (${\mu}XRD$), and (iii) micro-Raman spectroscopy. The monoclinic-phase fractions (M%) were compared by two-way ANOVA. RESULTS. InCoris Zi presented significantly higher M% than Ceramill Zi in both control and aged groups (P<.001). Both materials exhibited significant phase transformation with monoclinicphase of 1 to 3% more in aged groups than controls for all three assessment techniques. The comparable M% was quantified by both ${\mu}XRD$ and XRD. The highest M% was assessed with micro-Raman. CONCLUSION. Cyclic loading produced significant phase transformation in tested Y-TZP prostheses. The micro-Raman spectroscopy could be used as an alternative to XRD and ${\mu}XRD$.

A Study of Two Phase Flow Control in a Combustion Chamber (연소실내의 2상유동 제어에 관한 연구)

  • 박상규;김정훈;임종환
    • Journal of Advanced Marine Engineering and Technology
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    • v.25 no.3
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    • pp.637-643
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    • 2001
  • Two-phase flow in a combustion chamber is experimentally analyzed according to the five different conditions in the Reynolds numbers of $1.02{\times}10^4$. As the height difference between the primary and secondary jets increases, the secondary has a little less effect on the primary one in the case on the same height difference, the primary jet is affects as the velocity of th secondary on increase. The primary-jet flow field cause the particle concentration since is controlled by the velocity of secondary jet, the height difference, and the angle of primary jet in the test section.

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Analysis on Heat of Hydration for Height of Shell Concrete Pouring in Reactor Containment Building (원자로건물 외벽 타설 높이 산정을 위한 수화열 해석)

  • Kim, Jwa-Young;Park, Jong-Hyok;Lee, Han-Woo;Bang, Chang-Joon
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2012.11a
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    • pp.165-166
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    • 2012
  • A thermal stresses by heat of hydration was analyzed according to a change of a pour height in reactor containment building. In case of more than 3.6m pouring height a crack index by heat of hydration analysis resulted in less than 1 because there is not a construction joint of vertical direction and for a self-restraint effect of circumferential section shape. Therefore detailed consideration on a mixture proportion of binder type, quantity in concrete and selection of a form in seasonal air temperature is needed for a control of tensile stress by heat of hydration.

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Hierarchical Constructions of Digital Virtual Factory and its Management (디지털 가상공장의 계층적 구축과 운영에 관한 연구)

  • Kim Yu-Seok;Noh Sang-Do;Hah Sang-Dong;Shin Jong-Gye
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.960-964
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    • 2005
  • Digital Virtual Manufacturing is a technology to facilitate effective product developments and agile productions by digital models representing the physical and logical schema and the behavior of real manufacturing systems including products, process, manufacturing resources and plants. A digital virtual factory as a well-designed and integrated environment is essential for successful applications of this technology. In this research, we constructed a sophisticated digital virtual factory of the shipbuilding company's section steel shop by 3-D CAD and virtual manufacturing simulation. This digital virtual factory can be applied for diverse engineering activities in design, manufacturing and control of the real factory.

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An Application of the Mass Concrete Using Ternary Blended Cement (3성분계 시멘트를 사용한 매스콘크리트의 시공사례)

  • 권영호;하재담;전성근;김무한
    • Proceedings of the Korea Concrete Institute Conference
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    • 2001.11a
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    • pp.1229-1234
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    • 2001
  • The bottom slab of Inchon LNG in-ground #213 tank is designed as a massive structure witch has a large depth and section. The purpose of this study is to determine the optimum mix design having good workability and low hydration heat for bottom slab concrete and to control the actual concrete quality in site. For this purpose, we select the optimum mix design used ternary blended cement(furnace slag cement+fly ash) and design factors. As test results of actual application, we have finish placing the bottom slab concrete of 23,180㎥ during 68hours with good success and obtain the good quality of fresh and hardened concrete including slump, air contents, no-segregation, compressive strength and low hydration heat in actual data. All test results are satisfied with our specifications for bottom slab concrete and we cut costs as the use of ternary blended cement and the reduction of placing hours.

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