• Journal of Microbiology
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• 제41권3호
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• pp.239-247
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• 2003

The LRV1-4 capsid protein possesses an endoribonuclease activity that is responsible for the single site-specific cleavage in the 5' untranslated region (UTR) of its own viral RNA genome and the formation of a conserved stem-loop structure (stem-loop IV) in the UTR is essential for the accurate RNA cleavage by the capsid protein. To delineate the nucleotide sequences, which are essential for the correct formation of the stem-loop structure for the accurate RNA cleavage by the viral capsid protein, a wildtype minimal RNA transcript (RNA 5' 249-342) and several synthetic RNA transcripts encoding point-mutations in the stem-loop region were generated in an in vitro transcription system, and used as substrates for the RNA cleavage assay and RNase mapping studies. When the RNA 5' 249-342 transcript was subjected to RNase T1 and A mapping studies, the results showed that the predicted RNA secondary structure in the stem-loop region using FOLD analysis only existed in the presence of Mg$\^$2＋/ ions, suggesting that the metal ion stabilizes the stem-loop structure of the substrate RNA in solution. When point-mutated RNA substrates were used in the RNA cleavage assay and RNase T1 mapping study, the specific nucleotide sequences in the stem-loop region were not required for the accurate RNA cleavage by the viral capsid protein, but the formation of a stem-loop like structure in a region (nucleotides from 267 to 287) stabilized by Mg$\^$2＋/ ions was critical for the accurate RNA cleavage. The RNase T1 mapping and EMSA studies revealed that the Ca$\^$2＋/ and Mn$\^$2＋/ ions, among the reagents tested, could change the mobility of the substrate RNA 5' 249-342 on a gel similarly to that of Mg$\^$2＋/ ions, but only Ca$\^$2＋/ ions identically showed the stabilizing effect of Mg$\^$2＋/ ions on the stem-loop structure, suggesting that binding of the metal ions (Mg$\^$2＋/ or Ca$\^$2＋/) onto the RNA substrate in solution causes change and stabilization of the RNA stem-loop structure, and only the substrate RNA with a rigid stem-loop structure in the essential region can be accurately cleaved by the LRV1-4 viral capsid protein.

• Nuclear Engineering and Technology
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• 제47권2호
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• pp.157-164
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• 2015

Nuclear power plants have logical loop structures in their system configuration. This paper explains the method to solve a loop structure in reliability analysis. As examples of loop structured systems, the reactor core isolation cooling system and high-pressure core injection system of a boiling water reactor are considered and analyzed under a station blackout accident condition. The analysis results show the important role of loop structures under severe accidents. For the evaluation of the safety of nuclear power plants, it is necessary to accurately evaluate a loop structure's reliability.

• Journal of information and communication convergence engineering
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• 제8권5호
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• pp.489-492
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• 2010

This paper proposes the planar-type modified monopole antennas of loop structure. This antenna has an opened center of a conventional closed loop structure with an inside-folded terminal of the loop microstrip line. The size of the proposed antenna was minimized by folding the end of the loop. Also, the reactance value has been minimized by increasing capacitances between the coupled microstrip line. Therefore the proposed antenna has been compacted to about 20% from a conventional loop antenna and has increased its efficiency. The proposed antennas have an omni-directional pattern, the antenna gain was 3.67 [dBi] and the bandwidth was 900 MHz (2.6~3.56 GHz) with VSWR$\leq$2 from the simulated and the measured results. The frequency utilization coefficient was 29.9%. These properties could satisfy the S-DMB band.

• 조명전기설비학회논문지
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• 제28권2호
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• pp.100-108
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• 2014

In this paper, an idea of a network type distributed control of a system with inner loop control structure will be considered. Generally, in case of a control system with inner loop control structure, it is not easy to implement circuits and programming. Using network type distributed control structure, it will show how it is better than before. CAN(Controller Area Network) protocol which has been known that it has a high reliability on the signal in the various network protocols is used. Also, Arago's Disk System which has a inner loop control stucture is made to validate effectiveness of the proposed method.

• 대한안전경영과학회지
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• 제14권2호
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• pp.49-54
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• 2012

As all kind of industry has developed, metal structure and machine instrument use bolt, pin, rivet and welding for assembly and combination. For pin and hinge, dimension accuracy is crucial to keep the operation and safety of the structure and machine instrument. In case of complex machine, the hinge for cover open-loop system is one of the significant design elements. Most of the hinges are being imported and assembled sine they give high technology development cost for its unit cost position. The reason is that the localization of hinge is inadequate. As the demand increase and the necessity of localization grow, it is now more important than ever to develop low cost structure. By the low cost structure, a new technology could be obtained for electronic product and structural hinge since it would enable for complex machine hinge to be guaranteed, technologically. Open-loop hinge is the link type and designed for the structure to keep constant open-loop. And, the hinge is examined in design stability by finite element analysis method. In this paper, the operation result is presented when the hinge for complex machine open-loop is designed for link type structure.

• 대한수학회논문집
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• 제19권2호
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• pp.197-204
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• 2004

Every orthomodular lattice satisfying the loop lemma is the direct product of a Boolean algebra and an irreducible path-connected orthomodular lattice.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2004년도 ICEIC The International Conference on Electronics Informations and Communications
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• pp.334-338
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• 2004

In this paper, we suggest a new antenna structure for RFID(Radio Frequency IDentification) reader. Conventional RFID reader uses a loop antenna. The central area of a loop antenna shows a low magnetic field strength especially for the case of a large loop antenna diameter. We propose a parallel-fed multiple loop antenna. Simulation results and measured results show that we can adjust field distribution with the number of turns and diameter of an inner loop antenna to obtain a longer reading distance. Simulation results for the specific case of a proposed antenna structure show that at the center point of a proposed parallel-fed multiple loop antenna, the typical card area averaged magnetic field strength is 2.53A/m, which is higher than the case of a conventional type single loop antenna of 0.44A/m and the case of a series-fed multiple loop antenna of 0.96A/m when we drive with same source signal. We realized the antenna for the case of 13.56MHz RFID reader and the performance of reading distance was much more improved than the case of a conventional antenna.

• Molecules and Cells
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• 제24권3호
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• pp.378-387
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• 2007

The Bcl-2 family of proteins interacts at the mitochondria to regulate apoptosis. However, the anti-apoptotic Bcl-2 and $Bcl-X_L$ are not completely localized to the mitochondria. In an attempt to generate Bcl-2 and $Bcl-X_L$ chimeras that are constitutively localized to the mitochondria, we substituted their C-terminal transmembrane tail or both the C-terminal transmembrane tail and the adjacent loop with the equivalent regions from Bak or Bax mutant (BaxS184V) as these regions determine the mitochondrial localization of Bak and Bax. The effects of these substitutions on subcellular localization and their activities were assessed following expression in HeLa and CHO K1 cells. The substitution of the C-terminal tail or the C-terminal tail and the adjacent loop of Bcl-2 with the equivalent regions from Bak or the Bax mutant resulted in its association with the mitochondria. This change in subcellular localization of Bcl-2 chimeras triggered cells to undergo apoptotic-like cell death. The localization of this Bcl-2 chimera to the mitochondria may be associated with the disruption of mitochondrial membrane potential. Unlike Bcl-2, the loop structure adjacent to the C-terminal tail in $Bcl-X_L$ is crucial for its localization. To localize the $Bcl-X_L$ chimeras to the mitochondria, the loop structure next to the C-terminal tail in $Bcl-X_L$ protein must remain intact and cannot be substituted by the loop from Bax or Bak. The chimeric $Bcl-X_L$ with both its C-terminal tail and the loop structure replaced by the equivalent regions of Bak or Bax mutant localized throughout the entire cytosol. The $Bcl-X_L$ chimeras that are targeted to the mitochondria and the wild type $Bcl-X_L$ provided same protection against cell death under several death inducing conditions.

• ETRI Journal
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• 제16권2호
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• pp.1-13
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• 1994

We have identified two new features related to the coherent transport in the mesoscopic loop structure of aluminum wire, including the autocorrelation of the conductance fluctuations beyond $B_c$ and fine structure in the low-field magnetoresistance curve in the superconducting transition regime, which, to the best of our knowledge, have not been reported in the literature. Since the electrons in Al have a phase coherence length larger than $1\;{\mu}m$ at or below T = 3K, which is comparable to the dimensions of the structure, the wave nature of the electronic transport has been clearly observed: the universal conductance fluctuations, the Aharonov-Bohm oscillations, and the Altshuler-Aronov-Spivak oscillations. Due to the transition of Al to a superconducting state at T = 1.3 K, the coherent phenomena of Cooper pairs, i.e., the Little-Parks oscillations, have also been observed.

• 한국정보전자통신기술학회논문지
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• 제14권6호
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• pp.479-486
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• 2021

본 논문에서는 신호감지회로(Signal Sensing Circuit : SSC)를 추가하여 2개의 루프로 구성된 단일 커패시터 루프필터를 가진 극소형 위상고정루프(Phase Locked Loop : PLL)를 제안하였다. 위상고정루프 크기를 극단적으로 줄이기 위하여 가장 많은 면적을 차지하는 수동소자 루프필터를 극소형 단일 커패시터(2pF)로 설계하였다. 신호감지회로가 포함된 내부 부궤환 루프 출력이 외부 부궤환 루프의 단일 커패시터 루프필터 출력에 부궤환 역할을 하여 제안한 극소형 위상고정루프가 안정적으로 동작하도록 설계하였다. 위상고정루프 출력 신호 변화를 감지하는 신호 감지 회로는 루프필터의 커패시턴스 전하량을 조절하여 위상고정루프 출력 주파수의 초과 위상변이를 줄였다. 제안된 구조는 기존 구조에 비해 1/78 정도의 작은 커패시터를 가짐에도 불구하고 지터 크기는 10% 정도 차이가 난다. 본 논문의 위상고정루프는 1.8V 180nm 공정을 사용하였고, Spice를 통해 안정하게 동작하는 시뮬레이션 결과를 보여주었다.