• 대한공간정보학회지
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• 제4권1호
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• pp.75-82
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• 1996

퍼스널 컴퓨터(PC)를 기반으로 하는 지리정보 시스템을 이용하여 도시의 교통관련 시설물의 관리 및 교통관리를 지원하는 교통지리정보시스템 (GIS-T)이 소개되었다. 기존의 교통 시설물을 장부나, 카드식 대장에 의해 관리함으로써 설치형태나, 설치일, 교체주기 등의 관련통계자료 및 정보를 유지하는데 있어서 많은 시간과 노력이 필요하였으나 제안된 시스템을 이용하여 효율적인 시설물관리시스템은 물론 데이터의 공유 및 의사결정지원에 이르기까지 이용에 있어서 구청단위의 광범위한 활용도를 보여 주었다. 본 고에서는 현재 서울시 중구청에서 거의 구축이 완료된 교통시설물 관리시스템의 구축과정 및 시설물 관리 및 교통운영 측면에서의 활용방안에 대해서 살펴보았다. '중구교통관리시스템(CTMS)'이라고 명명된 이 시스템은 탁상 (Desktop) 환경을 기반으로 PC ARC/INFO 와 MapInfo를 이용하여 MS-Windows 95상에서 구축되었고 자치구 차원의 소규모 비용과 예산으로 교통관련 시설물을 관리, 운영, 및 더 나아가서 교통계획에 활용할 수 있는 가능성에 대해서도 검토되었다.

• Korean Journal of Acupuncture
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• 제21권1호
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• pp.103-112
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• 2004

Objectives : The aim of this study is to investigate the effect of Naegwan-acupuncture stimulation on the relationship of change in electrocardiopgraphy(ECG). Methods : For this purpose, 11 healthy volunteers were acupunctured at Naegwan acupoint using the reinforcing or reducing by inserting the needle in the same direction as the channel runs or in the opposite direction(迎隨補瀉). Then, we measured and observed the change of standard leads Ⅰ, Ⅱ and Ⅲ in ECG. Results : In lead Ⅰ, Naegwan acupuncture treated groups were increased the activity of PR interval and PR segment compared to the control group. In lead Ⅱ, Naegwan acupuncture treated groups were increased the activity of PR interval. In lead Ⅲ, Naegwan acupuncture treated groups were increased the activity of R wave duration, S wave amplitude, ST segment onset, ST segment midpoint, ST segment 80ms and ST segment endpoint. Conclusions : These results suggested that Naegwan acupuncture stimulation plays an important role to the activities of ECG.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.157-157
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• 2017

In last study, Genome-Wide Association Studies (GWAS) was conducted for cadmium content of 295 rice varieties including 137 rice core set and 157 Korea breeding varieties collected from Kongju National University. The results showed that 9 varieties had SNP allele and amino acid substitution in exon of chromosome 1. This study was aim to understanding mechanism of cadmium uptake to confirm correlation of cadmium and other mineral nutrients (Cu, Mn, Fe) among 9 rice varieties. Nine varieties were planted on polluted soil of mine in Korea and cadmium content in root, stem, leaf and it's brown rice was analyzed by ICP-MS (Inductively Coupled Plasma Mass spectrometer, Agilent 7700E, US). Results of this study showed that mechanism for cadmium uptake and accumulation was diversity among varieties. Chin-nong and Ho-nong contained higher levels of cadmium in root, but contained relatively lower levels cadmium in brown rice than other varieties. Cheong-nam, Nam-pyeong, Gan-cheok, Suan absorbed high levels of cadmium through root and then accumulated high cadmium to brown rice. Meanwhile, Yeong-deok and Su-kwang absorbed lower cadmium in root, but high cadmium was accumulated in brown rice. Correlations between cadmium and other mineral nutrients (Cu, Mn, Fe) were analyzed by using SPSS statistics 20. The contents of iron in leaf had minus correlation (p<0.05) with cooper and cadmium in root, cadmium in brown rice. Therefore understanding of cadmium uptake mechanism among varieties will be used to basic data for further breeding and phytoremediation.

• JSTS:Journal of Semiconductor Technology and Science
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• 제6권2호
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• pp.68-73
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• 2006

We propose a damascene gate FinFET with Si nanocrystals implemented on bulk silicon wafer for low voltage flash memory device. The use of optimized SRON (Silicon-Rich Oxynitride) process allows a high degree of control of the Si excess in the oxide. The FinFET with Si nanocrystals shows high program/erase (P/E) speed, large $V_{TH}$ shifts over 2.5V at 12V/$10{\mu}s$ for program and -12V/1ms for erase, good retention time, and acceptable endurance characteristics. Si nanocrystal memory with damascene gate FinFET is a solution of gate stack and voltage scaling for future generations of flash memory device. Index Terms-FinFET, Si-nanocrystal, SRON(Si-Rich Oxynitride), flash memory device.

• 한국환경보건학회지
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• 제43권6호
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• pp.457-466
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• 2017

Objectives: This study was carried out to investigate the characteristics of volatile organic compounds (VOCs) emitted from sewerage facilities such as a sanitary sewers, outlets, and catch basins. In addition, the dominant malodorous VOCs among the compounds in this study were studied. Methods: Waste gas samples were collected at 27 points in a sanitary sewer in commercial and residental areas. The concentrations of seven volatile organic compounds, including benzene and toluene, in the samples were analyzed by gas chromatograph mass spectrophotometer (GC/MS). Odor concentrations were estimated using the concentration data of the VOCs and each compound's threshold limit value. Results: As a result, it appeared that the average concentration of total observed data for acetaldehyde was 15.98 ppb and benzene 1.87 ppb, toluene 82.31 ppb, ethyl benzene 63.12 ppb, m+p-xylene 15.66 ppb, oxylene 18.73 ppb, and styrene 4.39 ppb. VOC concentrations in the commercial area were higher than those in the residential area. VOC concentrations of waste gas emitted from sewer lines was also higher than those at the outlet and in the catch basins. It was estimated that the main malodorous VOC among the seven VOCs was acetaldehyde. Conclusions: As there is little data on VOC concentrations inside sewer facilities in Korea, these data will be helpful for estimating impact assessment of VOCs and establishing a counter-plan for the abatement of VOCs from sewer facilities in the future.

• KSBB Journal
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• 제19권1호
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• pp.27-32
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• 2004

본 연구에서는 2차원 형광 센서를 이용하여 ALA 생산 공정을 실시간 모니터링하고 오프라인 분석 데이터와 비교, 고찰하였다. 배양액의 pH나 균체의 성장 특성 등 생물공정내의 환경 변화에 따라 형광 특성에 차이를 보였으며 최소배지인 MS8 배지에 IPTG, LA 및 기질 (포도당, 숙신산) 등을 첨가한 후 형광 특성의 변화를 살펴본 결과 균체의 성장이나 세포내 대사현상의 변화를 형광 차이로부터 확인할 수 있었다 2차원 형광센서에 의해 실시간 모니터링 된 형광 스펙트럼데이터는 기질 및 생산물 그리고 세포내 효소 활성 등의 각종 공정 변수와 좋은 상관성을 보였다. 따라서 본 연구에서 사용한 2차원 형광센서는 ALA 대량 생산을 위해 주요한 공정변수를 실시간 모니터링 하는데 매우 효과적이라 할 수 있으며 향후 공정의 제어 및 최적화에도 이용될 수 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.125-130
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• 2016

Nepeta cataria L. has been used in traditional medicine of some countries. Here the cytotoxic and apoptogenic activity of methanol extracts, n-hexane, dichloromethane, ethyl acetate, n-butanol, and acqueous extracts and the essential oil obtained from the aerial parts of the plant were evaluated with PC3, DU-145 and MCF-7 cell lines. Cell viability, histograms of PI stained fragmented DNA in apoptotic cells and Western blot analysis of proteins involved in the cascade of apoptosis were compared in all samples. Thirty components were identified as volatile, representing 99.7% of essential oil composition after GC-MS analysis of the oil obtained from aerial parts of the N. cataria by hydro-distillation. The major oil components of the essential oil were nepetalactone stereoisomers. Comparing IC50 values showed estrogen receptor positive PC3 cells were more sensitive to the cytotoxic effects of N. cataria in comparison with low hormone-receptor presenting DU-145 cells. Among multiple extracts and essential oils of the plant, only the ethyl acetate extract could significantly decrease cell viability in PC3 cells, in a concentration dependent manner. Ethyl acetate extract of N. cataria treated cells showed a sub-G1 peak in PC3 cells in a concentration dependent manner that indicates the involvement of an apoptotic process in ethyl acetate extract-induced cell death. Western blotting analysis showed that in PC3 cells treated with ethyl acetate (48 h) caspase 3 and PARP were cleaved to active forms. Overall, the results suggest that further analytical elucidation of N. cataria in respect to finding new cytotoxic chemicals with anti-tumor activity is warranted.

• Journal of Microbiology and Biotechnology
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• 제20권3호
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• pp.494-500
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• 2010

Bacterial blight, an important and potentially destructive bacterial disease in rice, is caused by Xanthomonas oryzae. Recently, this organism has developed resistance to available antibiotics, prompting scientists to find a suitable alternative. This study focused on secondary metabolites of Phomopsis longicolla to target X. oryzae. Five bioactive compounds were isolated by activity-guided fractionation from ethyl acetate extracts of mycelia and were identified by LC/MS and NMR spectroscopy as dicerandrol A, dicerandrol B, dicerandrol C, deacetylphomoxanthone B, and fusaristatin A. This is the first time fusaristatin A has been isolated from Phomopsis sp. Deacetylphomoxanthone B showed a higher antibacterial effect against X. oryzae KACC 10331 than the positive control (2,4-diacetyphloroglucinol). Dicerandrol A also showed high antimicrobial activity against Gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis) and yeast (Candida albicans). In addition, high production yields of these compounds were obtained at the stationary and death phases.

• 한국유기농업학회:학술대회논문집
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• 한국유기농학회 2009년도 하반기 학술대회
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• pp.319-319
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• 2009

관행재배 농산물에 대한 유기재배 농산물의 우수성이 구전되고 있으나 객관적인 과학적 데이터가 부족한 실정이다. 그래서 본 연구에서는 한국인이 주식으로 하고 있는 쌀(동진 1호)을 대상으로 생산이력이 분명한 유기 및 관행재배 시료를 이용하여 독자적으로 확립한 분석법을 이용해 유기 및 관행재배 쌀에 함유된 생리활성성분의 함량 비교를 행하였다. 생리활성성분 분석은 $\gamma$-oryzanol, $\beta$-sitosterol 및 tocopherol류를 대상으로 행하였다. 쌀에 함유된 주요 4종의 $\gamma$-oryzanol류의 동정을 위해 그 4종 화합물들을 ESI-MS 및 NMR 분석을 행한 결과, ODS 컬럼 상에서 cycloartenyl ferulate, 24-methylene cycloartenyl ferulate, campesteryl ferulate 및 $\beta$-sitosteryl ferulate 순으로 용출됨을 확인하였다. 동정된 각 성분들을 HPLC로 분석한 결과, cycloartenyl ferulate와 $\beta$-sitosteryl ferulate의 함량은관행보다 유기재배 쌀에서 유의(p<0.05)하게 높은 값을 보였다. 또한 $\gamma$-oryzanol 중 24-methylene cycloartenyl ferulate와 campesteryl ferulate의 함량은 유의차는 인정되지 않았으나 관행보다 유기재배 쌀에서 더 높은 경향을 보였다. 그리고 $\beta$-sitosterol 함량에 있어서는 유의차가 인정되지 않았으나 관행보다 유기재배 쌀에서 더 높은 경향을 나타냈다. 관행재배와 유기재배 쌀의 tocopherol류의 함량을 분석한 결과, $\alpha$-tocopherol의 함량에 있어서는 관행과 유기재배 쌀 간의 유의차가 관찰되지 않았고, $\beta$- and/or $\gamma$-tocopherols의 함량에 있어서는 유기재배 쌀에서 더 높은 경향이 관찰되었다. 이처럼 쌀에 함유된 생리활성 성분과 그로 인해 발휘되는 기능성 측면에 있어서 유기농산물의 우수성은 유기농산물 재배 농가의 수익 창출에 도움이 되는 홍보자료 제공 및 식품 기능학적 측면에 있어 중요한 기초자료로 활용될 수 있으리라 기대된다. 그러나 본 결과는 본 실험에서 대상으로 한 시료에 한정될 수 있으며, 유기재배 방법과 재배환경 및 조건에 따라 다양한 결과가 얻어질 수 있음에 주의가 요구된다.

• Journal of Microbiology
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• 제44권4호
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• pp.369-374
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• 2006

To investigate the mechanism of salt tolerance of gram-positive moderately halophilic bacteria, two-dimensional gel electrophoresis (2-D PAGE) was employed to achieve high resolution maps of proteins of Halobacillus dabanensis $D-8^T$. Approximately 700 spots of proteins were identified from these 2-D PAGE maps. The majority of these proteins had molecular weights between 17.5 and 66 kDa, and most of them were distributed between the isoelectric points (pI) 4.0 and 5.9. Some protein spots were distributed in the more acidic region of the 2-D gel (pI <4.0). This pattern indicated that a number of proteins in the strain $D-8^T$ are acidic. To understand the adaptation mechanisms of moderately halophilic bacteria in response to sudden environmental changes, differential protein profiles of this strain were investigated by 2-D PAGE and $Imagemaster^{TM}$ 2D Platinum software after the cells were subjected to salt shock of 1 to 25% salinity for 5 and 50 min. Analysis showed 59 proteins with an altered level of expression as the result of the exposure to salt shock. Eighteen proteins had increased expression, S proteins were induced, and the expression of 33 proteins was down-regulated. Eight of the up-regulated proteins were identified using MALDI-TOF/MS and MASCOT, and were similar to proteins involved in signal transduction, proteins participating in energy metabolism pathways and proteins involved in stress.