• Title/Summary/Keyword: 활성물질

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(7)대두의 생물 활성 물질 연구 개발 및 응용

  • Lee, Bu-Yong
    • Bulletin of Food Technology
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    • v.14 no.3
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    • pp.94-102
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    • 2001
  • 대두, 소위 황두는 중국, 아시아는 물론 세계에서 예로부터 광범위하게 식용으로 재배한 두류이다. 대두에는 식물성 유지와 단백질이 풍부하다. 역사 이래 인류는 콩으로부터 착유하거나 두부를 만들거나 동시에 가공하지 않고 직접 식용으로 이용하여 왔다. 근래에 두류에는 식물성 유지와 단백질 등의 영양소가 풍부하다는 것 이외에 새롭게 알려진 특수한 생물학적 작용을 하는 생리 활성 물질이 있다고 밝혀졌다. 그 예로는 대두 oligosaccharide, 대두 사포닌, 대두 이소플라본, 대두 인지질, 비타민 E 등이 있다.

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유전정보분석용 기반 소프트웨어시스템의 구축

  • Park, Gi-Jeong
    • Journal of Scientific & Technological Knowledge Infrastructure
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    • s.3
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    • pp.40-47
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    • 2000
  • 생명체의 대부분 현상은 유전정보에 기반하여 생성되는 생체활성물질의 상호작용에 의해 이루어지며, 생체활성물질의 대부분은 단백질들이다. 이들 각 단백질은 DNA의 일부분을 생성하기 위한 정보를 가지고 있는데, 각 단백질에 대한 이러한 부분을 유전자라고 한다.

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Effect of Terminalia chebula on Physiological Activity in Mice (가자(Terminalia chebula) 추출물이 마우스의 생리활성에 미치는 영향)

  • 박종옥;이승은
    • Journal of Life Science
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    • v.14 no.1
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    • pp.148-153
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    • 2004
  • In this study, we investigated the effect of water, extract of Terminalia Chebula (TC) on physiological activity in mice. TC water extract showed hemagglutination against several different types of red blood cells. $LD_{50}$ of TC extract was 390 mg/kg (po). Treatment of TC water extract orally administered 200, 300 mg/kg daily for one week. Hepatic cytosolic enzymes, xanthine oxidase and aldehyde oxidase activities were significantly increased comparison with normal group. Treatment of TC water extract increased hepatic malondialdehyde (MDA) formation, and reduced glutathione content. We also found that the decreased activities of glutathione S-transferase and glutathione reductase but was not affected activities of $\gamma$-glutamylcysteine synthetase after treatment of TC water extract. These results suggested that increase of the hepatic lipid peroxide is caused by glutathione reduction.

Polymer coating for controlled release of biostimulants from Biostimulant balls (생물활성촉진제의 용출율 제어를 위한 폴리머 코팅)

  • Song, Young-Chae;Woo, Jung-Hui;Senthilkumar, Palaninaicker
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2013.10a
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    • pp.46-47
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    • 2013
  • We prepared biostimulant balls using sea sediment mixed with biostimulants viz acetate, nitrate and sulfate. The Biostimulant balls were coated with Cellulose Acetate (CA) and Polysulfone (PS) to control the release of the biostimulants. SEM images showed that CA coating was porous and irregular in the inside and very uniform and tight like beehive while PS coating was the same in the inside and outside and not porous. Biostimulants release was found to be high in sea water compared to distilled water. The release of nitrate was higher compared to sulfate. In turbulent environment the release of bionutrients was 50% higher than static environment.

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A Study on the Application of Soil Washing Technology for HOCs-Contaminated Soil Using Mixed Surfactants (소수성 유기오염물질로 오염된 토양에 대한 혼합 계면활성제를 이용한 토양세척기법의 적용성 연구)

  • Choi, Sang-Il;Lee, Jai-Young;Jang, Min
    • Journal of the Korean Society of Groundwater Environment
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    • v.4 no.2
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    • pp.103-108
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    • 1997
  • A series of batch tests were conducted to evaluate the design parameters for the application of soil washing techniques to the hydrophobic organic compounds (HOCs)-contaminated soil using mixed surfactants. Because the mixed surfactants form different structures of molecular aggregates from single surfactant, they were applied to improve the washing efficiency. Kinds of surfactants added, mixing ratio, and total concentration of mixed surfactants were evaluated. The uncontaminated soil was obtained from a country hill near Nock-Chun Station in Seoul. The portion of soil passing #4 (4.75 mm) sieve was used. The pH, organic contents and cation exchange capacity were 4.4, 1.6% and 4.08 meq/100 g, respectively The soil was artificially contaminated by n-dodecane. The 5% solution of OA-5 and OA-14 (1:1) showed 86% washing efficency. The 4% solution of SDS and OA-5 (1:1) showed 95% washing efficiency.

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The Search for Naturally Occurring Herbicidal Compounds - I. Screening Search for Herbicidal Substances in Higher Plants (천연에서부터 제초활성물질의 탐색 - 제1보 식물체에 함유된 제초활성물질의 검색)

  • Ahn, J.W.;Kim, J.S.;Cho, K.Y.
    • Korean Journal of Weed Science
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    • v.9 no.1
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    • pp.69-75
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    • 1989
  • To search germination inhibitors in higher plants, first of all, some experiments containing selection of test weed seeds and effects of solvents and surfactants for bioassay establishment were conducted. Then MeOH-extracts of 45 plants were assayed for germination inhibition activities against Echinochloa crus-galli (L.) Beauv, Digitaria sanguinalis (L.) Scop., Cyperus iria L., Portulaca oleracea L. and Oenothera lamarckiana Ser. seeds. Among them extracts from Rhathiolepis ovata Briat and Picea abies (L.) Karst showed strong inhibitory effect (60-90% inhibition) on the germination of tested weed seeds at 5000 ppm. On the other hand, the extract from Youngia sonchifolia Max stimulated the germination and growth of tested weeds.

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A Study on Adsorption Characteristics of Benzene over Activated Carbons Coated with Insulating Materials and Desorption by Microwave Irradiation (절연물질이 코팅된 활성탄의 벤젠 흡착특성 및 마이크로파에 의한 탈착에 관한 연구)

  • Kim, Ki-Joong;Ahn, Ho-Geun
    • Applied Chemistry for Engineering
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    • v.19 no.4
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    • pp.445-451
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    • 2008
  • In order to regenerate the activated carbon polluted by volatile organic compounds (VOCs) using microwave, adsorption and desorption characteristics of benzene over activated carbon (AC) coated with insulating materials were investigated. Physical characteristics of activated carbon and insulator-coated ACs were investigated by means of $N_2$ gas adsorption and scanning electron microscopy (SEM). The amount of VOC adsorbed showed a positive relationship with the specific surface area of the ACs, and spark discharge over insulator-coated ACs did not occur. Potassium silicate (PS) was the best binder for coating of insulating materials on AC. Amount of benzene desorbed by microwave irradiation was dependent on output power of microwave. Nearly same performance was obtained even though the adsorption-desorption operation under microwave irradiation was repeated 5 times. Finally, it was known that the microwave heating was a very effective mean for regenerating the polluted AC.

Anticariogenic Effects and Inhibition of Glucosyltransferase Activity of Chrysanthemun indicum L. Extracts (감국(Chrysanthemun indicum L.) 추출물의 항충치효과와 Glucosyltransferase 저해활성 탐색)

  • Kim, Seon-Jae;Park, Yun-Mi;Jung, Soon-Teck
    • Journal of the Korean Society of Food Culture
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    • v.20 no.3
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    • pp.341-345
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    • 2005
  • The anticariogenic effects and inhibition of glucosyltransferase activity of Chrysanthemun indicum L. extracts were investigated against 5 strains of microorganisms. The ethanol extracts of Chrysanthemun indicum L. showed the growth inhibition effects on the Streptococcus mutans and oral bacteria. The inhibition rate of glucosyltransferase activity of Chrysanthemun indicum L. extracts showed 78.4 to 92.3% range. The extracts were analysed by using solvent fractionation, silica gel adsorption chromatography, Sephadex LH-20 column chromatography, TLC, HPLC techniques. Three components whose molecular weights ranged from 200 to 400 were confirmed to have the anticariogenic activity.

Growth Stimulation of Lactic Acid Bacteria by a Radish Component (무의 젖산균 증식촉진물질과 촉진작용)

  • Park, Kyung-Suk;Kyung, Kyu-Hang
    • Korean Journal of Food Science and Technology
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    • v.24 no.6
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    • pp.528-534
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    • 1992
  • Growth stimulatory material for lactic acid bacteria was extracted from radish and radish green juice and its growth stimulatory effect was tested. Dried methanol-precipitated growth stimulatory material was lightly grayish white powder, Its ash content is 44% and approximately 50% of the ash is sulfur. It has reddish brown color upon solubilization in water. The material had unchanged stimulatory effect when it was treated with proteinase or pectinase, or ashed. The growth stimulatory activity was dialyzable. The material was able to counteract the growth inhibitory effect of EDTA. When selected lactic acid bacteria were grown at $30^{\circ}C$ for 24 hours in peptone(0.5%)-yeast extract(0.5%)-glucose(2%) broth with and without 0.5% growth stimulatory material, the material stimulated the growth of Lactobacillus plantarum, L. fermentum, L. leichmanii, L. sake, L. brevis, L. acidophilus, L. casei, Pediococcus pentosaceus, Leuconostoc mesenteroides, Streptococcus faecalis, S. lactis, S. cremoris and S. thermophilus by 19, 1833, 133, 444, 840, 32, 14, 18, 6, 17, 4, 5 and 4 times, respectively.

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향신료의 활성산소 포촉인자

  • 정신교
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 1993.12a
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    • pp.10-11
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    • 1993
  • 기저상태의 산소분자는 비교적 안정하지만 생체ㅇ내외에서 물리적, 화학적으로 활성화 되어 $O_{2}$, $^{1}O_{2}$, OH, $H_{2}O_{2}$ 등의 활성산소종을 생성하며, 생체의 지질, 단백질, 핵산 당등의 분자에 산화적 상해를 초래하여 노화, 암, 순환기, 호흡기 게통의 질환과 식품의 품질열화에 관여하는 것으로 알려져 있다. 따라서 본인은 식품의 맛, 향기, 색 등을 부여하는 고유의 기능 외에도 방부제, 한방약으로 널리 이용되고 오고 있는 51종의 향신료를 대상으로 활성산소포촉활성을 조사하고 나아가 활성물질을 분리, 정제 및 동정함으로 향신료의 새로운 기능을 밝히고 신약 개발의 기초적 자료를 제시하고저 한다. Fenton 반응을 이용하여 2-deozyribose 산화법과 sodium benzoic acid 수산화법으로 51종의 향신료의 OH 포촉활성을 검색한 결과, Cruciferae과의 nustard 류, Labiatae과의 thyme, saga, savory, oregano, Myrtaceae과의 clove, allspice 가 1ug/ml 농도에서 50%이상의 포촉활성을 나타내었으며 그중 mustard 류는 같은 농도에서 거의 90%이상의 활성을 나타내었다. 활성물질의 분리 및 정제는 Amberlite XAD-2 갈럼과 preparative-HPLC를 이용 하였으며, EI, FAB-MS, IR, $^{1}H$, $^{13}C-NMR$, Cosy-NMR로 그 화학적 구조를 동정하였다. Brown mustard에서 동정된 4-hydroxy-3,5-dimethoxy cinnamic acid Methyl ester는 0.42$\mu$ mol 농도에서 90% 이상의 OH 포촉활성을 나타내어 이를 diazomethane 반응으로 조제하였으며 white mistard에서는 4-hydroxy-3,5-dimethoxy cinnamoyl choline을 동정하였다.

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