Background: In patients with obstructive sleep apnea syndrome(OSAS), there are several factors increasing upper airway resistance and there is a predisposition to compromised respiratory function during waking and sleep related to constitutional factors including a tendency to obesity. Several recent studies have suggested a possible relationship between sleep apnea(SA) and systemic hypertension. But the possible pathophysiologic link between SA and hypertension is still unclear. In this study, we have examined the relationship among age, body mass index(BMI), pulmonary function parameters and polysomnographic data in patients with OSAS. And also we tried to know the difference among these parameters between hypertensive OSAS and normotensive OSAS patients. Methods: Patients underwent a full night of polysomnography and measured pulmonary function during waking. OSAS was diagnosed if patients had more than 5 apneas per hour(apnea index, AI). A careful history of previously known or present hypertension was obtained from each patient, and patients with systolic blood pressure $\geq$ 160mmHg and/or diastolic blood pressure $\geq$ 95mmHg were classified as hypertensives. Results: The noctural nadir of arterial oxygen saturation($SaO_2$ nadir) was negatively related to AI and respiratory disturbance index(RDI), and the degree of noctural oxygen desaturation(DOD) was positively related to AI and RDI. BMI contributed to AI, RDI, $SaO_2$ nadir and DOD values. And also BMI contributed to $FEV_1,\;FEV_1/FVC$ and DLco values. There was a correlation between airway resistance(Raw) and AI, and there was a inverse correlation between DLco and DOD. But there was no difference among these parameters between hypertensive OSAS and normotensive OSAS patients. Conclusion: The obesity contributed to the compromised respiratory function and the severity of OSAS. AI and RDI were important factors in the severity of hypoxia during sleep. The measurement of pulmonary function parameters including Raw and DLco may be helpful in the prediction and assessment of OSAS patients. But we could not find clear difference between hypertensive and normotensive OSAS patients.
Purpose: This study was designed to determine the optimum radiotherapy technique for internal mammary node (IMN) irradiation after breast-conserving surgery. Materials and Methods: We selected ten cases of early stage partial mastectomy for plan comparison. Five of the patients were treated to the right-side breast and the rest of the patients were treated to the left-side breast. For each case, four different treatment plans were made to irradiate the entire breast, IMNs and supraclavicular lymph nodes (SCLs). The four planning techniques include a standard tangential field (STF), wide tangential field (WTF), partially wide tangential field (PWT) and a photon-electron mixed field (PEM). We prescribed a dose of 50.4 Gy to the SCL field at a 3 cm depth and isocenter of the breast field. Results: The dose distribution showed clear characteristics depending on the technique used. All of the techniques covered the breast tissue well. IMN coverage was also good, except for the STF, which was not intended to cover IMNs. For the cases of the left-side breasts, the volume of the heart that received more than 30 Gy was larger (in order) for the WTF, PWT, PEM and STF. For radiation pneumonitis normal tissue complication probability (NTCP), the PWT showed the best results followed by the STF. Conclusion: Despite the variety of patient body shapes, the PWT technique showed the best results for coverage of IMNs and for reducing the lung and heart dose.
Purpose: This study was done to identify fat distribution and blood pressure according to anthropometric change patterns between NIDDM patients and control subjects. Methods: Cross-sectionally 167 NIDDM patients and 87 controls were studied. Previous maximal body weight and acute weight loss was obtained. Current height, body weight, BMI, waist-hip ratio(WHR), skinfold thicknesses(abdomen, subscapular & triceps), and blood pressure was measured. Three anthropometric change patterns were categorized by BMI changes from the maximum lifetim's BMI to the current time (obese-obese, obese-nonobese and nonobese-nonobese: obese: BMI$\geq$25kg/m$^2$, nonobese: BMI<25kg/m$^2$). The data was analyzed by $X^2$, t-test, age adjusted ANCOVA and Least Squares Means(LSM) for multiple comparison. Result: Acute body weight loss(p=0.01), anthropometric change types (p=0.001), WHR (p=0.05), and skinfold thickness (p=0.002) of NIDDM were significantly higher than those of the controls. The mean arterial pressure, WHR and skinfold thicknesses were greater in both obese-obese and obese-nonobese NIDDM and control subjects compared with both nonobese-nonobese NIDDM and control subjects. (all p's<0.05). Conclusion: NIDDM patients had more central and upper body adiposicity. Also both obese-obese and obese-nonobese NIDDM and control subjects had higher mean arterial pressures and central body obesity.
The Journal of Churna Manual Medicine for Spine and Nerves
/
v.10
no.1
/
pp.47-61
/
2015
Objectives : The purpose of this study is body parameters characteristics through posture analysis system of musculoskeletal problem patient Methods : Posture analysis system were performed for 164 patients to measure body parameters such as Q-angle, body inclination, neck inclination, PCMT(posterior cervical muscle tension), Knee flexion and posture balance. Statistical analysis using statistical analysis techniques and Pearson correlation coefficients was performed to assess the body parameters obtained by posture analysis system. Results : More than half of people out of 164 reported low back pain, 34.8% of the total was found to have neck pain. There was not a significant difference between genders from the characteristics of gender based body parameters expect for the statistical difference in Q angle, PCMT. There was a significant correlation between low back pain and multiple response status. There was a significant correlations between knee pain and Q angle. Also There was a significant correlations between pelvic pain and posture balance of ankle. Conclusions : Posture analysis system can be used to perform the analysis in place of X-ray measuring body posture and clinical parameters. The results of this study are expected to be the basis for further research on the clinical application of posture analysis system.
Purpose : This study was carried out to compare actual obesity rate, body shape perception and weight control between outpatients visiting obesity center and general population in the $20{\sim}30$ age bracket. Methods : The respondents were 72 females including 38 outpatients and 34 general population in the $20{\sim}30$ age bracket. We compared the results of the questionnaires about body shape, obesity and weight control between two groups. Data were analyzed by Student T-test and Chi-square test. Results : In questionnaire survey results, the average BMI, obesity rate, body shape distortion of the respondents who have normal weight, concern for weight control in outpatients group were significantly higher than general population group. Satisfaction on weight control in distorted group was lower than undistorted group. Conclusion : A distortion of the body shape caused unsatisfaction on weight control and it was significantly high in outpatients group, especially among the respondents who have normal weight. It is considered that the distortion of the body shape should be corrected by counselling for proper treatment.
Se-hun Kim;Seong-hun Yu;Tae-won Kim;Seong-hwan Kim;Se-jin Park
The Journal of Korean Academy of Orthopedic Manual Physical Therapy
/
v.30
no.1
/
pp.85-93
/
2024
Background: This study examined the Immediate effects of IASTM using microcurrent and the flossing band on the lower extremity fascia thickness in subjects with Intrinsic patellofemoral pain syndrome. Methods: Sixty-six subjects with patellofemoral pain syndrome were randomized into three groups (22 each in the microcurrent IASTM (instrument assisted soft-tissue mobilization) group, and flossing band group, and combined microcurrent IASTM and flossing band group) to evaluate the immediate effects of the lower extremity fascia thickness before and after intervention. The thickness of the lower extremity fascia was measured using an ultrasound machine. Using SPSS Window. 22.0, a Shapiro Wilk was conducted to test the normality of all variables; within-group comparisons were made with a paired-samples t-test, and between-group interventions were subjected to a one-way analysis of variance. Results: Changes in the thickness of the fascia in the thigh area were observed before and after intervention in all three groups. There was a significant decrease, and in the combined group, there was a significant decrease in fascia thickness compared to when the IASTM group and the flossing band group were applied separately (p<.05). Conclusion: Through this study, the effect on fascia thickness was confirmed when IASTM and flossing band intervention were combined, and it is believed that it can be used as basic clinical data for patients with knee-thigh pain syndrome.
Purpose: In digital mammography QC program was used for the purpose of reducing low-dose and high-definition images of the radiation dose. Materials and Methods: In digital mammography using a QC phantom according to the average glandular dose in the exposure method MLO view $0^{\circ}C$, $30^{\circ}C$, $45^{\circ}C$, $50^{\circ}C$, $55^{\circ}C$, $70^{\circ}C$, was measured at $90^{\circ}C$ intervals, an image with Hologic QC program to the SNR and CNR was measured to evaluate. Results: The average dose in the MLO view was wired to $90^{\circ}C$ when the maximum was 1.75 mGy, it decreased approximately 6% was measured at $45^{\circ}C$ 1.65 mGy. In addition, 1.67 mGy, manual record, there were an average wired in accordance with the exposure dose and the dose of 1.52 mGy difference in the way auto filter. Image quality evaluation at every angular section SNR 50 ~ 52, shows a slight difference in CNR 11 ~ 12, it was included in the manufacturer's recommended value. Conclusion: The dose was lowest in MLO view $45^{\circ}C$, the difference between SNR and CNR were insignificant. The method of exposure will need a way to reduce the exposure of the patient's body or unnecessary patient by placing a difference in settings in which the characteristics.
Cho, Seok Won;Ham, Joon-Chul;Kang, Chun Goo;Bahn, Young Kag;Lee, Seung Jae;Lim, Han Sang;Lee, Chang-Ho;Park, Hoon-Hee
The Korean Journal of Nuclear Medicine Technology
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v.17
no.2
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pp.72-77
/
2013
Purpose: Whole-body PET using radiopharmaceutical is one of the imaging study methods for physiological changes of body. High specificity of the PET-CT examination is used to detect an early stages of cancer and metastatic cancer by imaging a physiological changes. During the imaging process, PET image has been characterized by a relatively low image quality due to its low sensitivity and the acquisition of random and scatter coincidences as well as patients figure. Therefore, the image quality as the changes of the acquisition times of patient weight was evaluated in this study. Materials and Methods: Thirty patients who presented to our hospital were enrolled. They were divided to normal, overweight, and obese group using BMI index, respectively. The patients with a liver disease and diabetes were excluded. $^{18}F-FDG$ was administered to the patients as 5.2 MBq per kg. After an hour from an injection, image acquisition was obtained as List mode in a part of liver in 1 bed. SNR (signal-to-noise ratio) of each groups acquisition times were confirmed from the calculated radiation counts and random fractions. The statistical significance of three groups was confirmed through one-way ANOVA test. On the basis of the counts of 2 minutes on normal group, the SNR of overweight group and obese group were compared. Results: The SNR were increased with loger aquisition time in 3 groups. In the condition of same acquisition time, the SNR had a statistical significance (P<0.05). The SNR were decreased to the normal, overweight, and obese, respectively. Liver activity had no significance difference on each group and RF had the significance differences (P<0.05). On the basis of the counts of 2 minutes on normal group, there were no statistical significance in a three minute acquisitions of overweight group and two minute acquisitions of obese group (P=0.150). Conclusion: In this study, the administrated amount of radiation dose did not adjust as the change of the patients weight. Increasing the acquisition time when the administration of the same amount of dose was able to get a good result of SNR. When the Based 2 minute on normal group, if overweight and obese case the increased acquisition time of 3 minute was able to obtain a similar SNR. On the basis of the normal group, the acquisition times of overweight and obese group were increased to 3 minutes per bed and the SNR were similar to the normal group.
Purpose: The purpose of this study was to ascertain whether radiation adaptive response could be induced by Tc-99m-methylene diphosphonate (Tc-99m-MDP) in peripheral lymphocytes of patients undergoing bone scintigraphy. Materials and Methods: Lymphocytes from 22 patients (6 males, 16 females, mean age $50{\pm}14$ years) were collected before and after bone scintigraphy using 740 MBq Tc-99m-MDP Lymphocytes from 10 controls (6 males, 4 females, mean age $43{\pm}7$ years) were also collected. They were exposed to challenge dose of 2 Gy gamma rays using a cell irradiator. Number of ring-form and dicentric chromosomes per 600 cells (chromosomal aberrations) was counted under the light microscope. Results: Chromosomal aberrations in patients before bone scintigraphy ($385.1{\pm}30.5$) was not different from that of controls ($367.8{\pm}36.6$). However, chromosomal aberrations in patients after bone scintigraphy was significantly decreased to $192.6{\pm}22.1$ (p=0.0001). Conclusion: Low dose gamma-irradiation by Tc-99m-MDP used for bone scintigraphy induces a cytogenetic adaptive response in peripheral lymphocytes.
Since SBRT takes up to 1 hour from 30 minutes to treatment fraction once or three to five times, there is a possibility of setup error during treatment. To reduce these set-up errors and give accurate doses, we intend to evaluate the usefulness of pre-treatment and post-treatment error values by imaging CBCT again to determine postural movement due to pre-treatment coordinate values using pre-treatment CBCT. On average, the range of systematic errors was 0.032 to 0.17 on the X and Y,Z axes, confirming that there was very little change in movement even after treatment. Tumor centripetal changes (±SD) due to respiratory tuning were 0.11 (±0.12) cm, 0.27 (±0.15) cm, and 0.21 cm (±0.31 cm) in the X, Y and Z directions. The tumor edges ±SD were 0.21 (±0.18) cm, 0.30 (±0.23) cm, and 0.19 cm (±0.26) cm in the X, Y and Z directions. The (±SD) of tumor-corrected displacements were 0.03 (±0.16) cm, 0.05 (±0.26) cm, and 0.02 (±0.23) cm in RL, AP, and SI directions, respectively. The range of the 3D vector value was 0.11 to 0-.18 cm on average when comparing pre-treatment and CBCT, and it was confirmed that the corrected set-up error was within 0.3 cm. Therefore, it was confirmed that there were some changes in values depending on some older patients, condition on the day of treatment, and body type, but they were within the significance range.
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