• Title/Summary/Keyword: 홍국

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Physiological Activity of Roasted Coffee prepared from Fermented Green Coffee Bean with Monascus ruber Mycelium (홍국균(Monascus ruber) 균사체-커피생두 발효물로부터 조제된 원두커피의 생리활성)

  • Kim, Hoon;Suh, Hyung-Joo;Shin, Ji-Young;Hwang, Jong-Hyun;Yu, Kwang-Won
    • The Korean Journal of Food And Nutrition
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    • v.29 no.1
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    • pp.1-11
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    • 2016
  • To enhance the physiological activities of roasted coffee (RC), 30 kinds of green coffee beans (GCB) with different cultivating areas and varieties were fermented with Monascus ruber mycelium (MR) by solid-state culture. After the dried MR-fermented GCB was subjected medium roasting, each RC was extracted with hot-water. Among the hot-water extracts, the highest yield was the hot-water extract of RC from MR-fermented Indonesia Mandheling GCB (15.5%). However, the hot-water extract of RC from MR-fermented Ethiopia Sidamo GCB showed significantly higher polyphenolic contents (3.08 mg GAE/100 mg) and ABTS free radical scavenging activity (25.41 mg AEAC/100 mg). Meanwhile, the hot-water extract of RC from MR-fermented Vietnam Robusta GCB showed not only the effective inhibition of $TNF-{\alpha}$ level (73.7% inhibition of LPS-stimulated control) from LPS-stimulated RAW 264.7 cells but also significant inhibition of lipogenesis (63.5% inhibition of lipid differentiation control) in 3T3-L1 pre-adipose cells. In conclusion, these results suggest that roasted coffees from Ethiopia Sidamo and Vietnam Robusta green coffee beans fermented with Monascus ruber mycelium using solid-state culture could have industrial applications as functional coffee beverages.

Proposal and Analysis of Characteristics of a Refractive Index Modulated Distributed Feedback Laser Diode (Refractive Index Modulated Distributed Feedback Laser Diode의 제안과 특성해석)

  • 김홍국;이홍석;김부균;김병호
    • Journal of the Korean Institute of Telematics and Electronics D
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    • v.36D no.5
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    • pp.88-98
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    • 1999
  • A refractive index modulated (RIM) DFB laser, in which the refractive index of a center region of the upper cladding layer comprising the grating region is different from that of side regions, is proposed to obtain and effective ${\lambda}$/4 phase shift in the center region. Since the coupling coefficient of a center region in a RIM-DFB laser is larger than that of side regions, a RIM-DFB laser has the effect of a distributed coupling coefficient. Simulation results show that RIM-DFB lasers have better operation characteristics - more uniform photon density profile, less SHB effect, and better single mode operation at high injection currents - compared to those of ${\lambda}$/4 phase-shifted DFB lasers and CPM-DFB lasers. In addition, the effect of the center region on the above threshold characteristics of a RIM-DFB laser is investigated.

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Effects of Red-Yeast-Rice Supplementation on Blood Lipids and Relations among Cholesterol, Bone Markers, and Hormones in Overiectomized Rats (난소 절제 쥐에서 홍국의 첨가가 혈중 지질에 미치는 영향과 혈중 콜레스테롤과 골대사 지표 및 호르몬과의 관련성)

  • Choi Mi-Ja;Yu Tae-Shick
    • Journal of the East Asian Society of Dietary Life
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    • v.15 no.3
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    • pp.264-270
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    • 2005
  • This study was performed to evaluate the effect of red-yeast-rice on blood lipids and also to investigated the relation of blood lipids, bone related hormones, and bone mineral density in overiectomized rats. Forty female rats (body weight $210\pm5$g) were divided into two groups. The rats in the first group were ovariectomized which the others received sham operation (SHAM). And then each rat group was further divided into control diet $(casein\;20\%)$ and red-yeast-rice powder supplemented $(0.1\%)$ diet group. All rats were fed on experimental diet and deionized water ad libitum for 9 weeks. Bone mineral density (BMD) and bone mineral content (BMC) were measured using PIXImus in spine and femur. Bone formation and bone resorption were measured by serum osteocalcin and urinary deoxypyridinoline (DPD) crosslinks value. Serum growth hormone, IGF-1 and calcitonin were analyzed using radioimmunoassay kits. The red-yeast-rice group had significantly lower the blood triglyceride concentration and had lower the blood total cholesterol concentration than casein group did in ovariectomized rats. And the red-yeast-rice group than casein group in ovariectomized rats. The red-yeast-rice group had significantly lower the atherogenic index than control group within the ovariectomized groups. In the experimental rats, serum total cholesterol concentration was negatively correlated with femur BMC and crosslink value. Crosslink value was negatively correlated with spine BMC and IGF-1. Osteocalcin concentration was negatively correlated with crosslink value. Growth hormone was negatively correlated with crosslink value and positively correlated with spine BMC. The findings of this study suggest that red-yeast-rices are beneficial for blood lipid in ovariectomized rats. And when considering a population-based public health approach to lowering cholesterol and bone loss, and preventing coronary heart disease and osteoporosis, the red-yeast-rice dietary supplement could provide a new approach for the maintenance of healthier cholesterol and bone.

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Automatic Tuning Architecture of RC Time-Constant due to the Variation of Integrated Passive Components (집적된 수동 소자 변동에 의한 RC 시상수 자동 보정 기법)

  • Lee, Sung-Dae;Hong, Kuk-Tae;Jang, Myung-Jun;Chung, Kang-Min
    • Journal of Sensor Science and Technology
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    • v.6 no.2
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    • pp.115-122
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    • 1997
  • In this paper, on-chp atomatic tuning circuit, using proposed integration level approximation technique, is designed to tuning of the variation of RC time-constant due to aging or temperature variation, etc. This circuit reduces the error, the difference between code values and real outputs of integrator, which is drawback of presented dual-slope tuning circuit and eliminates modulations of processing signals in integrated circuit due to fixed tuning codes during ordinary operation. This system is made up of simple integrator, A/D converter and digital control circuit and all capacitors are replaced by programed capacitor arrays in this system. This tuning circuit with 4 bit resolution achieves $-9.74{\sim}+9.68%$ of RC time constant error for 50% resistance variation.

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Aortic Translocation for Complete Transposition of the Great Arteries with a Ventricular Septal Defect and Pulmonic Stenosis (심실 중격 결손과 폐동맥 협착을 동반한 완전 대혈관 전위에서 대동맥 전위술)

  • Jeong, In-Seok;Lee, Chang-Ha;Lee, Cheul;Lim, Hong-Gook;Kim, In-Sub;Youn, Hyo-Chul
    • Journal of Chest Surgery
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    • v.41 no.4
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    • pp.476-479
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    • 2008
  • The Rastelli operation has been a standard procedure for repairing complete transposition of the great arteries combined with a ventricular septal defect and pulmonary stenosis. Yet this procedure has several shortcomings, including the risk of incurring left ventricular outflow tract obstruction on long-term follow-up. In this regard, aortic translocation has recently been regarded as a potent alternative to Rastelli's operation. We report here on a case of complete transposition of the great arteries that was combined with an inlet-extended perimembranous ventricular septal defect and pulmonary stenosis in a 2-year-old boy. All the problems were successfully repaired using the aortic translocation technique. Postoperative echocardiography showed a straight and wide left ventricular outflow tract.

Composition-control of Mn-Zn Ferrite Single Crystal Using a Phase Diagram (상평형도를 이용한 Mn-Zn 페라이트 단결정 조성 조절)

  • Je, Hae-June;Kim, In-Tae;Hong, Kug-Sun
    • Analytical Science and Technology
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    • v.5 no.3
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    • pp.327-332
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    • 1992
  • Mn-Zn ferrite single crystals show some fluctuations in composition along the direction of growth by the conventional Bridgman method. The single crystal with a uniform composition was obtained by maintaining the liquid composition content. For example, two batches of powder were prepared : one is consisted of 52 mol% of $Fe_2O_3$, 30 mol% of MnO, and 18 mol% Zn(Composition A), and the other 53 mol% of $Fe_2O_3$, 28.5 mol% of MnO, and 18.5 mol% ZnO(Composition B). Crack-free single crystals with the uniform composition B were grown in a size of 60mm diameter, 300mm long by melting the pellets of composition A and followed by supplying the composition B as tablets. Initial permeabilities were obtained above 600 at 5 MHz in the region of 30~270 mm along the direction of growth.

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Half-turned Truncal Switch Operation for Transposition of Great Arteries, Ventricular Septal Defect and Pulmonic Stenosis (폐동맥 협착과 심실 중격 결손을 동반한 대혈관 전위에서 시행한 반회전 동맥간 전환술)

  • Lim Hong Gook;Hwang Seong Wook;Lee Cheul;Kim Chong Whan;Kim Jun Seok;Lee Chang-Ha
    • Journal of Chest Surgery
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    • v.39 no.2 s.259
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    • pp.145-149
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    • 2006
  • The surgical management of patients with transposition of the great arteries, ventricular septal defect, and pulmonary stenosis remains a challenge. The Rastelli operation or Lecompte operation is the preferred surgical procedure, but its long-term results are not optimal because of a warped left ventricular outflow tract through a space-occupied intraventricular tunnel and a contrived right ventricular outflow tract. We performed a half-turned truncal switch operation as an alternative surgical procedure in a 3-year-old boy (weighing 9.6 kg) with this anomaly. Postoperative echocardiography showed laminar flow through straight and nonobstructive aortic and pulmonary ventricular outflow tracts.

Fistula of Ascending Aorta and Right Atrium Following Percutaneous Transcatheter Atrial Septal Defect Closure (경피적 카테타 심방중격결손 폐쇄술 후 발생한 상행 대동맥-우심방루)

  • Um Hong Gook;Seo Hong Joo;Kim Chong Whan;Kim Jun Seok;Lee Chang-Ha
    • Journal of Chest Surgery
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    • v.39 no.2 s.259
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    • pp.150-153
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    • 2006
  • Percutaneous transcatheter closure of atrial septal defects as a therapeutic alternative in appropriate patients provides superior cosmetic results, is less invasive, and allows for shorter hospital stays. Unfortunately, however, such percutaneous procedures can be associated with catastrophic procedure complications that may require immediate surgical intervention. We report a case of aorta-to-right atrial fistula two months after transcatheter occlusion of an atrial septal defect by an Amplatzer septal occluder. Revealed by dyspnea, palpitation and hemolysis, this complication needed an emergency surgical operation. The fistula between the noncoronary Valsalva sinus of the aorta and the right atrium was repaired. The atrial septal defect was closed by patch. The cause of this serious complication appears to be erosion into the aorta by the right atrial disk.

Production and Characteristics of Hongkuk-ju using Monascus anka (Monascus anka를 이용한 홍국주의 제조 및 특성)

  • Bang, Byung-Ho;Rhee, Moon-Soo;Kim, Kwan-Pil;Lee, Ki-Won;Yi, Dong-Heui
    • The Korean Journal of Food And Nutrition
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    • v.26 no.1
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    • pp.78-84
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    • 2013
  • To reproduce the brewing process of Hongkuk-ju and to identify the functional properties of it, Hongkuk-ju was brewed using different additions of Hongkuk (100%, 90%, 70%, 50%) and Nuruk (0%, 10%, 30%, 50%). The quality elements, including pH, total acidity, reducing sugar content, alcohol content and pigments (yellow, red, monacolin K and citrinin), were measured. The pH values of Hongkuk-ju showed a slight difference (pH 4.08~4.58) right after the $1^{st}$ stage mash; further, the pH on all groups (H1, H2, H3 and H4) in the terminal of the $2^{nd}$ stage mash (9 days in fermentation) were similar, ranging approximately at pH 3.70. The total acidity change did not show a difference directly the $1^{st}$ stage mash (nearby 0.2 %); however, it began to show a slight difference at the terminal of the $2^{nd}$ stage mash between the range of 0.69~0.76%. The residual reducing sugar of the content was decreased with the increased Nuruk content. The alcohol concentrations of the treatment brew with Nuruk ranging from 12.3% to 13.7% were higher than Hongkuk on its own. The yellow and red pigment contents of Hongkuk-ju ranged from 7.2~8.8 O.D. units (yellow pigment) and from 4.4~5.1 O.D. units (red pigment). The production of monacolin K and citrinin was the highest (9.48 mg/kg and 10.14 mg/kg) when the treatment solely brewed Hongkuk. The concentration of Nuruk and the preparation of the seed mash from it were critical factors compared to the treatment of rice in brewing Hongkuk-ju.

Successful Rescue of Refractory Ventricular Tachycardia after One and a Half Repair in Ebstein's Anomaly by Extracorporeal Membrane Oxygenation (부분 양심실 교정을 받은 엡스타인 기형에서 발생한 심실성 빈맥에 대해 체외막 산소화 장치를 이용한 성공적인 구출)

  • Seo, Hong-Joo;Whang, Sung-Wook;Lee, Cheul;Lim, Hong-Gook;Yu, Jai-Kun;Lee, Chang-Ha
    • Journal of Chest Surgery
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    • v.40 no.3 s.272
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    • pp.220-224
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    • 2007
  • Extracorporeal membrane oxygenation (ECMO) provides mechanical cardiopulmonary support and has been used for children with severe respiratory failure, intractable heart failure, sepsis, pulmonary hypertension, and as a bridge to heart transplantation. There have been few reports of the use of ECMO to provide cardiac support in children with low cardiac output as a result of arrhythmias. We report the case of a 15-year-old female with circulatory collapse due to refractory ventricular arrhythmia after one and a half repair in Ebstein's anomaly, who was successfully resuscitated using ECMO.