• Title/Summary/Keyword: 혈중 생화학적 지표

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여성의 갱년기 증상과 혈중 총항산화능 및 식이섭취와의 관련성 분석

  • 김순경;연보영;선우재근
    • Proceedings of the KSCN Conference
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    • 2004.05a
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    • pp.422.2-423
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    • 2004
  • 폐경을 전ㆍ후한 여성들의 갱년기 증상과 혈중 총항산화능과의 관련성 및 총항산화능에 영향을 미치는 식사요인을 알아보기 위하여 45-55세 여성(평균 연령 48.89 $\pm$ 3.64세, 신장 156.27 $\pm$ 4.77 cm, 체중 60.90 $\pm$ 6.89 Kg, BMI 24.96 Kg/$m^2$) 105명을 대상으로 갱년기 증상의 유ㆍ무에 관한 사항, 신체계측 및 식이섭취 상태등에 관한 조사와 혈중 총항산화능을 비롯한 생화학적 지표들을 측정하였다.(중략)

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Effect of Dietary Soybean Hydrolysate on Plasma Lipid Profiles, Select Biochemical Indexes, and Histopathological Changes in Spontaneously Hypertensive Rats (대두가수분해물 유래 펩타이드 투여가 자발성 고혈압 흰쥐의 혈중 지질수준, 생화학적 지표 및 조직병리학적 변화에 미치는 영향)

  • Chung, Sun-Wha;Choi, Min-Ah;Park, Jeong-Soon;Kim, Kil-Soo;Chung, Dae-Kyun;Nam, Hee-Sop;Shin, Zae-Ik;Yu, Ri-Na
    • Korean Journal of Food Science and Technology
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    • v.31 no.4
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    • pp.1101-1108
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    • 1999
  • Soybean (SoyPep) was prepared and evaluated their action on blood lipid profiles, select biochemical indexes and histopathological changes in spontaneously hypertensive rat (SHR). Male SHRs were divided into three groups and fed the experimental diet containing 0% (control), 3%, 10% SoyPep for 8 weeks. Lipids, antioxidative vitamin levels, glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) activities in plasma were measured, and angiotensin I converting enzyme (ACE) activities in kidney, vascular tissue and plasma were also measured. In addition, histopathological changes in various organs were investigated. Dietary SoyPep was effective for lowering plasma levels of triglyceride and LDL-cholesterol. ACE activities in aorta and kidney were decreased in the group fed SoyPep compared to control. There was no difference of plasma GOT and GPT activities, and no histopathological difference in various organs among the experimental groups. Our results suggest that SoyPep has beneficial effects on diseases such as hypertension and atherosclerosis. SoyPep could be useful to develop a novel functional safe food additive for preventing the chronic diseases.

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The effects of education for hemodialysis patients with a family caregiver on self-care practice and blood biochemical parameters (혈액투석 환자의 가족참여교육이 자가간호수행과 혈액생화학적 지표에 미치는 영향)

  • Park, Ji Hyun;Choi, Hyunkyung
    • Journal of the Korean Data and Information Science Society
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    • v.27 no.2
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    • pp.487-498
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    • 2016
  • The purpose of this study was to identify the effects of education for hemodialysis patient with a family caregiver on self-care practice and on blood biochemical parameters. A nonequivalent control group pretest and posttest design has been employed for analysis. Among hemodialysis patients in C university hospital located in Daegu, 56 subjects, 28 in experimental and 28 in control group, participated in the study from April to May in 2015. The experimental group whose family caregiver participated in education for hemodialysis patient reported significant differences in self-care practice (t=3.36, p=.001) and serum potassium level (t=2.78, p=.007) from the control group whose family caregiver did not participate. Considering positive effects of family education, we suggest education programs incorporating family caregivers be used as an effective nursing intervention.

MMPI 와 생리적 특성간의 상관성 분석

  • 박세권;정연수;김동수
    • Proceedings of the Korean Statistical Society Conference
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    • 2004.11a
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    • pp.111-116
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    • 2004
  • 스트레스 수준이 논을 것으로 예상되는 공군사관학교 수험생의 신체검사 결과로부터 신체건강 지표인 혈액 내 생화학적 요인들과 정신건강 지표인 다면 인성검사 점수를 추출하여 통계적 상관성 및 유의성을 비교 분석하였다 사관생도들 중 $10\%$의 표본을 추출하여 사관생도와 수험생 집단간의 특성 비교를 위한 비교집단으로 이용하였다. 수험생과 사관생도 집단 간의 특성 요인 비교는 Mann-whitney U 검정과 Kruskal-Wallis 검정을 이용하였다. 수험생 집단 내에서 혈중 요인 및 정신건강 지표인 MMPI 점수는 정상범주에 있었고 두 요인 간 상관성은 발견할 수 없었다. 그러나 사관생도와 수험생 집단 간의 특성 요인들에 대한 유의성 검정 결과, 특히 2학년생도들의 혈액 내 혈구 수 및 활동성 또는 적극성과 관련된 MMPI 하위척도에서 수험생 집단과 매운 유의한 차이를 보이는 특이한 현상을 발견할 수 있었고 이에 대한 해석을 언급하였다.

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Antifatigue Effect of Chlorella vulgaris in Mice (클로렐라의 항 피로 효과 연구)

  • An Hyo-Jin;Seo Sang-Wan;Sim Kyung-Sik;Kim Jung-Suk;Kim Eun-Hee;Lee Mi-Ok;Park Hyeung-Suk;Han Jae-Gab;Lee Eun-Hee;Um Jae-Young;Hong Seung-Heon;Kim Hyung-Min
    • The Korean Journal of Food And Nutrition
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    • v.19 no.2
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    • pp.169-175
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    • 2006
  • A unicellular algae, Chlorella vulgaris(CV), was used as a biological response modifier. The effect of CV on forced swimming test and blood biochemical parameters related to fatigue was investigated. Blood urea nitrogen(BUN); creatine kinase(CK); lactic dehydrogenase(LDH); glucose(Glc); total protein(TP); and albumin were determined. CV was orally administered to mice in the range of 0.05 to 0.15 g/kg/day. A forced swimming test results on 3 and 7 day after administration of CV, showed that immobility time was decreased in the CV-administered group(0.15 g/kg). In addition, the contents of BUN in the blood serum were decreased in CV-fed group. The contents of CK and LDH were tended to decrease, but not statistically significant. The plasma Glc level was increased in CV-fed groups(0.05 and 0.1 g/kg) compared to control group. It had no effect on the elevation of TP and albumin level. The results indicate that CV could improve physical stamina.

Effects of the Ethanol Extract from Lycii folium Leaves on Obesity and Blood Biochemical Indices in High-fat Diet Induced Obese Rats (구기엽 에탄올 추출물이 고지방 식이 유도 비만쥐의 비만과 혈중 생화학적 지표 조절에 미치는 영향)

  • Choi, Mi-Kyeong;Lee, Jae-Soon;Park, Won-Jong;Kim, Mi-Hyun;Kang, Myung-Hwa
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.12
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    • pp.1707-1711
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    • 2009
  • This study was conducted to investigate the effects of ethanol extract from Lycii folium (L. folium) leaves on obesity index, serum lipids, homocysteine, leptin, ghrelin, and glucose in obese rats. Sprague-Dawley rats were administrated high-fat diets to induce obesity. Then, obese rats were divided into three diet groups: a basal-diet obese group (BO group), high-fat diet obese group (FO group), and high-fat diet plus L. folium extract obese group (FLEO group). Three groups were each fed experimental diet for 8 weeks. There were no significant differences in body weight and FER among the groups. However, obesity index such as Ro?hrer index, Lee index, and T.M. index of FLEO group was significantly decreased as compared to FO group. While serum triglyceride of BO group was significantly decreased as compared to FO group, there were no significant differences in serum lipids, homocysteine, leptin, ghrelin and glucose between FLEO group and FO group. In conclusion, these results indicated that ethanol extract from L. folium leaves might be beneficial with anti-obese effect by reduction of obesity indices in obese rats.

Relationship among Body Composition, Biochemical Measurements and Serum Leptin Level in Obese Children (비만아의 체성분 및 생화학적 측정치와 혈중 Leptin 농도와의 관계)

  • 최봉순;손수진;이희자;박명희;이은주
    • Journal of Nutrition and Health
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    • v.35 no.4
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    • pp.454-463
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    • 2002
  • The purpose of this study was to investigate the relationship among the anthropometric measurements, body composition indices, biochemical indices and serum leptin level of obese school children. The study was conducted on 97 elementary school children from 4-5th grade residing in Daegu and Kyungbuk area. Obesity was defined as fat percentage that exceed 25% of body fat mass. The prevalence of obesity of subject was 58.3% for male and 54.1% for female. The mean value of height, weight, body composition indices and biochemical indices of obese group were significantly higher than those of control group. The leptin level was significantly different in obese group but showed no difference by gender. The differences of leptin level were according to adiposity and BMI in obese subjects. Multiple regression analysis data showed that the BMI and body fat mass may influence on the leptin level of subject. Also, these data revealed the leptin resistance in obese children and relationship between leptin level and various factors including anthropometric measurements, body composition and biochemical indices. Additional research should be necessary to assess the mechanism of leptin resistance in obese children.

The Effect of Red Ginseng Extracts on Blood Biochemical Parameters, Bone Density and Bone Inorganic Components in Ovariectomized Rats (홍삼추출물이 난소절제 흰쥐의 혈액 생화학적 지표, 골 밀도 및 골무기질에 미치는 영향)

  • Kim, Byung-Weon;Lee, Yoon-Bok;Park, Jae-Seung;Park, Ji-Won;Hwang, Seock-Yeon
    • Journal of Digital Convergence
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    • v.11 no.10
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    • pp.493-505
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    • 2013
  • We investigated the effect of red ginseng extracts on blood biochemical parameters, bone density and bone inorganic components etc. and data were analyzed by one-way ANOVA and Post-Hoc Test. In the results of our study, the level of albumin and HDL, Ca, P, Mg, and estradiol in blood, and the content of Ca, P, ash in femur were significantly increased in red ginseng treated group than in OVX group, and the level of ALP, AST, ALT, blood glucose, total cholesterol, triglyceride, LDL, creatinine, osteocalcin, and N-terminal telopeptide were significantly decreased in red ginseng treated group than in OVX group (p < 0.01). From these results, we knew that within the normal level, red ginseng extracts improved liver and kidney function, component of glucose and lipid in blood, bone density, bone ash and inorganic components in femur, and index related with bone metabolism.

Effect of Silkworm (Bombyx mori) Excrement Powder on the Alcoholic Hepatotoxicit in Rats (알코올성 간독성에 미치는 누에배설물의 영향)

  • Kim, Yong-Soon;Kim, Kee-Young;Kang, Pil-Don;Cha, Jae-Young;Heo, Jin-Sun;Park, Bo-Kyung;Cho, Young-Su
    • Journal of Life Science
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    • v.18 no.10
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    • pp.1342-1347
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    • 2008
  • The purpose of present study was to investigate the protective effect of silkworm excrement powder (SEP) on alcohol-induced hepatotoxicity in rats. Semisynthetic diet supplemented with SEP (3%, w/w) given to alcohol-feeding rats for 30 days, then blood and tissues were collected, processed and used for alcohol concentration mensuration, various biochemical estimations and histopathological examination. Chronic alcohol administration resulted in significantly increase in the activities of the clinically important liver marker enzymes, alanine aminotransferase (ALT), aspartate aminotransferase (AST), $\gamma$-glutamyl transpeptidase ($\gamma$-GTP) and lactate dehydrogenase (LDH). Also, a highly significant increase in the blood alcohol level by alcohol treatment was observed. But alcohol-induced elevation of ALT and LDH levels markedly prevented and the level of blood alcohol decreased in SEP treated rats as compared to alcohol-administered control rats. SEP supplementation showed highly decreased the concentrations of total lipid, triglyceride and cholesterol in serum, as compared with alcohol treated control rats. Alcohol treatment induced the marked accumulation of large lipid droplets, hepatocytes necrosis and inflammation in the liver, but SEP administration attenuated to alcohol-induced accumulation of lipid droplets and hepatocyte necrosis. The results indicated that SEP may exert a protective effect against alcoholic hepatotoxicity through decreasing the activity of hepatic marker enzymes.