• Clinical and Experimental Reproductive Medicine
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• v.3 no.2
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• pp.29-34
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• 1976

The changes of the plasma progestin concentations in normal pregnancy and artificially maintained pregnancy of the rabbits by hormonal replace therapy after induced ovulation and insemination on Day 1, followed by ovariectomy on Day 2, were checked by direct measurement, competitive protein-binding assay, from the time of mating through to parturition. The results obstained in this experiment can be summarized as follows: (i) The mean concentration of progestin in normally pregnant rabbits increased from $1.7{\sim}2.7$ ng/ml on Day 1 to $19.8{\sim}25.3$ ng/ml on Days $13{\sim}15$ and declined slowly thereafter until term. (ii) The progesterone levels in artificially maintained pregnancy by hormonal replacement therapy showed quite a similar pattern to that in normally pregnant rabbits.

• Journal of Life Science
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• v.30 no.9
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• pp.791-797
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• 2020

Maqui berry are known as one of the "superfoods" and can purportedly improve health. The effects of orally administered maqui berry extract on biological parameters such as serum lipids and blood cells in healthy subjects were investigated in rats in vivo for 2 weeks. Possible causes of harmful effects on liver and kidney function were also examined. After oral administration of maqui berry extract, levels of serum triglyceride (TG) were decreased to almost 30% less from the control, and high density lipoprotein cholesterol (HDL-C) was increased to 18% more; thus, serum lipids profile seemed to be improved. The administration of maqui berry extract increased red blood cell concentration by 10% from the control, while both the hemoglobin and the mean corpuscular volume (MCV) were increased by 12%. Maqui berry extract also increased the concentration of serum total proteins by 30% of the control and that suggests protein metabolism might be improved. Moreover, maqui berry decreased serum levels of glutamin oxaloacetate transaminase (GOT) and glutamin pyruvate transaminase (GPT) by 12% from the control group so maqui berry improved liver function. This study suggests that oral administration of maqui berry extract may be helpful to improve those heath parameters like serum lipids profile, red blood cell level, liver protection. It would also be very useful for the development of high value products such as functional foods and pharmaceutics in the future.

• Journal of the East Asian Society of Dietary Life
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• v.23 no.1
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• pp.31-38
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• 2013

This study was designed to evaluate the effect of a rice-based diet on body weight and serum lipid levels. Thirty male C57BL/6 mice were randomly divided into three groups and fed a high-fat diet (HFD), rice-based diet (RD), or bread-based diet (BD) for five weeks. Our results showed that the RD group had a significantly lower final body weight, although there was no significant difference in daily food intake among the groups. There was a reduction in body weight gains, adipose tissues weight, and adipocyte size of epididymal adipose tissue in the RD group (p<0.05). Also, serum triglycerides and total cholesterol in the RD group were significantly decreased compared to the BD group. RD also reduced fasting glucose and insulin levels. These results indicate that the intake of RD attenuates increases in body weight and serum lipid concentrations in mice, suggesting its benefits for the dietary control of obesity and hyperlipidemia.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.6
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• pp.226-232
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• 2016

In the elderly, a lower muscle mass and higher body fat mass are induced by a lower level of physical activity. A negatively changed body composition with an advanced age can lead to a higher falling risk and rate of diseases. On the other hand, aerobic-type exercise positively influences the body composition and hyperlipidemia in the elderly. Therefore, this study examined the effects of aquarobic training for 12 weeks on the body composition and blood lipid levels in obese old women. The subjects (n = 31, body fat: 33.42%) completed a 12 week water based aerobic training at 12 - 13 of Borg Scale of intensity (three times per week, each session: an hour). The body composition was measured by bioelectrical impedance analysis (Inbody 770-Biospace, Seoul, Korea) and the concentrations of blood lipids (high-density lipids cholesterol (HDL), low-density lipids cholesterol (LDL), triglyceride (TG) total cholesterol (TC)) were determined at pre and post training. A paired t-test was used for data analysis with ${\alpha}=0.05$. In the results, the body composition (% body fat (p < 0.05) and waist circumference (p < 0.05)) were reduced significantly. The LDL (p < 0.05), TG (p < 0.001) and TC (p < 0.05) were reduced significantly. In conclusion, a 12 week aquarobic exercise program helps improve the body composition and concentrations of serum lipids. Therefore, aquarobic exercise can enhance lipolysis using fat as energy to induce an improvement of the body composition and induce hyperlipidemia.

• Journal of Life Science
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• v.18 no.7
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• pp.999-1004
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• 2008

The effects of Bulnesia sarmienti water extract on lipid metabolism were investigated in type-2 diabetes rats. The rats were fed a basal diet and B. sarmienti water extract for 8 weeks. The rats were randomly assigned to each treatment group : normal, control, two kinds of treatment group (BW1: 0.9 mg/ml, BW2: 1.8 mg/ml). After 8 weeks of experimental diets consumption, the body weights and food efficiency ratio of B. sarmienti water extract fed groups were not different from those in the control group. The concentrations of total-cholesterol, LDL-cholesterol, and triglyceride in blood plasma were significantly decreased in the B. sarmienti water extract groups comparison to the control group. Although blood glucose control effects were not observed, the B. sarmienti water extract feeds were highly effective in lowering the levels of blood lipid substances such as triglycerides, total-cholesterol, and LDL-cholesterol.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.10
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• pp.1508-1512
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• 2016

This study was performed to investigate the ameliorating effect of a mixture of extracts from Houttuynia cordata Thunb, Nelumbo nucifera G. (leaf), and Camellia sinensis (seed) (MIX) on acute ethanol-induced hangover in Sprague-Dawley rats. Plasma ethanol and acetaldehyde levels in MIX-treated rats significantly decreased at 3 h and 5 h after acute ethanol administration (25%, 3 g/kg body weight/d) as compared to ethanol-treated rats. Hepatic alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities were significantly higher in MIX-treated rats than in ethanol-treated rats. MIX exhibited high ADH and ALDH activities on direct assays using S9 rat liver fraction for ethanol metabolic enzymes clearance action. These results suggest that MIX could alleviate ethanol-induced hangover symptoms by elevating activities related to hepatic ethanol-metabolizing enzymes against ethanol induced metabolites, and MIX should be further developed to be a new anti-hangover material.

• Korean Journal of Animal Reproduction
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• v.25 no.1
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• pp.9-17
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• 2001

To determine the effect of the characteristics of the corpus luteum (CL) and serum metabolites on pregnancy rate following embryo transfer in Hanwoo cow, recipients were synchronized the estrus with CIDR. in vivo or in vitro produced bovine embryos were transferred to synchronized recipients. The characteristics of the CL were checked by rectal palpation and ultrasound. Blood samples were collected from jugular vein at Day 7 and analysed progesterone and serum metabolites. The results obtained from this study were as follows; 1. Total 397 embryos were transferred to recipient and 121 heads out of them were pregnant. The pregnancy rate was 30.5% and slightly differences between farms. 2. There was not significantly different the pregnancy rates between the size of CL and the cavity CL. In the recipients which had more than 2ng/$m\ell$ of serum progesterone level, the pregnancy rates was in higher than others (46.6% vs. 24.4%, 15.0%). 3. The highest pregnancy rate was obtained at 90 to 110mg/㎗ in serum total cholesterol, 14 to 16mg/㎗ in BUN, and 70 to 80mg/㎗ in serum glucose, respectively, and these metabolites in blood could be used as the criteria in the selection of recipient at embryo transfer.

• Korean Journal of Food Science and Technology
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• v.36 no.4
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• pp.604-608
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• 2004

Possibility of Lactobacillus strains able to metabolize ethanol and acetaldehyde in vitro and in vitro was studied. Lactobacillus brevis strains showed higher alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) activities than those of other lactic acid bacteria strains. L. brevis HY7401 exhibited the highest ADH and ALDH activities and decreased considerable amounts of ethanol and acetaldehyde in vitro. L. brevis HY7401 cell intake significantly decreased serum ethanol levels in rats fed ethanol (4g/kg BW) compared to control groups. Ethanol level in small intestines of rats fed L. brevis HY7401 was about 50%, and their acetic acid concentration was twofold higher than control. Results reveal L. brevis HY7401, isolated from human, metabolizes ethanol and acetaldehyde in vitro and in vivo.

• Science of Emotion and Sensibility
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• v.9 no.1
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• pp.1-7
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• 2006

The purpose of this study is to analyze the effects of the inhalation of 30% oxygen on heart rate and oxygen saturation ($SPO_2$) during cycle isokinetic exercise, in comparison with the inhalation of 21% oxygen. This study used oxygen supply equipment that can supply each of 21% and 30% oxygen constantly at a rate of 8 liter/min. Ten healthy male college students ($25.2{\pm}2.2$ years) participated in the experiment twice, one for 21% oxygen and the other for 30% oxygen. Each experiment was composed of three sections (a total of 18 minutes), which were composure (2 minutes), cycle isokinetic exercise at a speed of $20{\pm}1km/h$ (10 minutes) and recovery (6 minutes). 21% or 30% oxygen was supplied only during the sections of isokinetic exercise and restoration. Heart rate during isokinetic exercise and recovery was lower with the inhalation of 30% oxygen than with that of 20% oxygen but no difference was observed in $SPO_2$. $SPO_2$ was not different possibly because the same work load was applied to the group of 21% oxygen and that of 30% oxygen. Heart rate was reduced with the inhalation of 30% oxygen possibly because a larger quantity of oxygen was supplied at the same work load.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.1
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• pp.498-506
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• 2015

This paper investigates the association of among alcohol consumption and blood vitamin D and lead concentrations. Subjects to 4,074 with adults over the age of 20 in the 5th Korea National Health and Nutrition Examination Survey, correlation analysis is used to validate the relations between an average daily alcohol consumption and blood vitamin D and lead concentration, and to study the effects of blood vitamin D to the lead concentration is carried out regression analysis. The correlation analysis shows that alcohol consumption has the correlation with blood vitamin D and lead concentration(p<0.01). As the results of regression analysis, age(p<0.01), education(p<0.01), occupation(p<0.05), alcohol consumption(p<0.01), vitamin D(p<0.05) appear significant influence on lead concentration in male. Alcohol consumption increases not only lead concentration but also vitamin D. Blood vitamin D also contributes to the rise in lead concentration, but in the reverse the metabolic activity of blood vitamin D by influence of lead receives a negative effect in our body.