• The Science & Technology
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• no.11 s.414
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• pp.8-10
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• 2003

동물원 야생동물 이상행동 관찰돼/ 동전 크기 칩에 인간유전자 집적/ 흉터 없는 초고속 상처치료 물질 발견/ 글리백, 알츠하이머 병에도 효과/ CERN, 12개국 참여 차세대 컴퓨터망 구축/ 적색육, 인체에 해로운 면역반응 유발/ 스트레스 비만과 각종 성인병 유발/ '푸들'종 개 게놈지도 작성/ 줄기세포, 난자에서도 추출 가능/ 첫 육지식물 4억7천500만년 전 출현/ 고대 그리스數체계는 이집트에서 차용

• Korean Journal of Psychosomatic Medicine
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• v.32 no.1
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• pp.10-23
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• 2024

This study examines the changes in attractiveness and social perception of mask wearers during the COVID-19 pandemic. Before COVID-19, masks were seen as a sign of infection, decreasing the wearer's attractiveness. However, with the widespread normalization of mask-wearing during the pandemic, the perception mechanisms have become more complex. The attractiveness and social perception of mask wearers now vary based on factors such as the wearer's baseline attractiveness, race, and attitudes toward masks. Consequently, research findings on perception changes due to mask-wearing have been inconsistent. This inconsistency is due to the lack of standardized experimental methods and the failure to account for individual differences among participants, as well as insufficient theoretical background in the studies. From a psychiatric perspective, it is essential to formulate and test new hypotheses centered around the psychological mechanisms related to the human behavioral immune system when studying attractiveness perception during a pandemic. Notably, attention should be given to how differences in the activation of individuals' behavioral immune systems influence perceptions of mask wearers. Understanding these dynamics can provide crucial insights into how social perceptions and aversions impact mental health, thereby shedding light on various psychiatric issues that arise during infectious disease outbreaks.

• Korean Journal of Psychosomatic Medicine
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• v.8 no.1
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• pp.46-57
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• 2000

Objectives : The purpose of the present study was to examine the effect of subacute treatment with the selective serotonin reuptake inhibitors(paroxetine and sertraline) on immobility in the forced swim test(FST) and on FST-induced changes in immune parameters of the mice. Methods : Authors applied a modified method of FST by Porsolt et al. Over 5 BALB/c mice were used for each group of experiments. To explore the changes in immune parameters by FST, authors investigated the production of anti-rat RBC antibody, concanavalin A(ConA)- or lipopolysaccharide(LPS)-stimulated splenocytes proliferation assay and cytokine gene expression. Results : Both paroxetine and sertraline decreased the duration of immobility in a dose-related manner. FST-performed mice showed a significant decrease in mitogenic responses of splenocytes and a slight increasing tendency in anti-rat RBC antibody response. All these responses were attenuated significantly by paroxetine and attenuated nearly nominal significance level by sertraline. The cytokine profiles of ConA-stimulated splenocytes from FST-performed mice showed stronger expression of IL-4 and weaker expression of IL-2 than control mice, and no changes in the expressions of IFN-$\gamma$ and lymphotoxin. IL-6 and IL-10 were not expressed in both group of mice. The pretreatment of paroxetine and sertraline attenuated the altered cytokine expressions in FST-performed mice to some extent. Some alterations of the expressions of IL-6 and IL-10 were observed in the mice which the selective serotonin reuptake inhibitors had been pretreated. Conclusion : The subacute treatment of paroxetine and sertraline attenuated the FST-induced behavioral and immune changes, and these serotonin reuptake inhibitors may exert some modulating effects on the immune system by the induction of cytokine gene expression, especially IL-6 and IL-10.

• Korean Journal of Psychosomatic Medicine
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• v.2 no.1
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• pp.3-9
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• 1994

The psychobiological model of cancer has a long history, with Galen's view on melancholic woman being often quoted. From a historical perspective, the 1950s witnessed a surge of interest in psychosomatic medicine and in researches linking psychological, social, and environmental factors to disease onset and progression. The 1960s witnessed the growth of animal experiements, in the hope of better understanding the effects of psychological and behavioral factors on carcinogenesis while controlling confounding variables. The 1970s saw rapid advances in immunology and neurochemistry. Further researches in the 1980s in psychoneuroimmunology explored relationships between immunological responses and psychosocial variables, and their implications for cancer vulnerability and progression. In this review, the interacting aspects of oncology and psychiatry are presented with selected major findings in the fold of psychooncology researches.