• Journal of Sasang Constitutional Medicine
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• v.18 no.3
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• pp.166-174
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• 2006

1. Objects The objectives of this study were to examine the present state of Oriental clinical service based on Constitutional medicine and to make an accurate estimate of it’s scale after 10 years. 2. Methods The data for this study were collected from a questionnaire survey to 319 Traditional Korean Medical doctors who were selected as random samples. And this questionnaire is consist of several inquiries related with management and application of constitutional medicine. 3. Results and Conclusions The major results of this survey are following: l. The 52.8% facilities of all Oriental medical centers and Clinics in the whole country are applying Constitutional medicine for treating patients. 2. The 24.8% persons of all health workers are engaged in Constitutional clinical service. 3. The proportion of sales by Constitutional clinical services to the total sales by Traditional clinical service is 23.5% in 2005. 4. The proportion of application to medical care insurance by Constitutional clinical service is 17.9% of all amounts After taking these results into consideration, the sales of Constitutional clinical service now are estimated to make up 23.8% percent of the total traditional medical service and the amount of it’s sales after 10 years is expected to increase up to 3.6 times as much as the current quantity.

• Journal of Fashion Business
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• v.19 no.2
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• pp.103-117
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• 2015

The purpose of this study was to examine the uniform image of Korean herbal cosmetic brands amongst Korean and Chinese consumers. This study would enable us to explore a BI strategy to enhance international competitiveness of Korean herbal cosmetics brands. The results were as follows. The key words of BI pursued by Sulwhasoo were dignified, novel, graceful, soft, gaily, natural, Korean, modern, and international. Korean people felt that the uniform was graceful and soft, which accorded with Sulwhasoo BI, but also it was trite and dingy, indicating a negative and opposing image. On the other hand, Chinese people felt that the uniform was dignified, novel, graceful, natural, modern, and international, indicating that it matched with Sulwhasoo BI. In The History of Whoo, the key words of BI pursued by the brand were precious, soft, gorgeous, gaily, and natural. The Koreans felt that the uniform was intelligent, and decent, but conversely, it was also austere and dingy, indicating a negative image. The Chinese felt that the uniform was common, hard, austere, dingy, and unnatural, indicating an opposing image to BI. Finally, a uniform design was developed to improve on its problems, establish The History of Whoo's brand identity, and its brand image. First of all, 'The Quintessence : noble passion' was set up as a developmental concept. The textiles, clothing, and accessories were designed using the symbolic elements from The History of Whoo as a motif. Uniforms were developed for spring, fall, and summer.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.04a
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• pp.45-45
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• 2019

학술림은 학생, 교수, 산림 연구기관의 실험 실습 등의 연구 기능을 하는 숲이며, 경제적, 사회적 및 환경적으로 큰 의미가 있어, 학술연구 및 교육에 있어서 중요한 필수 자산이다. 국내에 분포하는 학술림의 전체면적은 약 34,941ha로 국내 전체 면적 6,335,000ha의 0.55%를 차지하고 있다. 국내 학술림을 행정적으로 남부, 중부 및 북부 세권역으로 나눠볼 수 있는데 중부권역에 속해있는 한 곳인 국민대학교 학술림의 자생식물을 조사하였다. 국민대학교 학술림이 위치한 경상북도 안동시 길안면 배방리 일대는 청송 유네스코 세계지질공원 및 주왕산국립공원과 인접함에도 불구하고 연구가 부족한 실정이다. 본 연구에서 확인된 관속식물은 97과 292속 518종 등 총 518분류군으로 조사되었으며, 산림청지정 희귀식물로는 댕댕이나무, 산분꽃나무, 시호, 솜양지꽃, 산마늘 등 10분류군이 확인되었고, 특산식물은 청괴불나무, 참배암차즈기, 고려엉겅퀴, 분취 등 9분류군이 확인되었다. 식물구계학적 특정식물은 I등급은 고려엉겅퀴, 백선, 뻐꾹채, 초롱꽃, 투구꽃 등 26분류군, II등급은 곰취, 구와취, 노랑제비꽃, 채고추나물, 호오리새 등 11분류군, III등급은 복자기, 시닥나무, 참조팝나무, 눈개승마, 다북떡쑥 등 24분류군, Ⅳ등급은 개아마, 뚝사초, 산마늘, 왜방풍, 참배암차즈기 등 8분류군, V등급은 산분꽃나무 1분류군으로 확인되었다.

• Korean Journal of Pharmacognosy
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• v.49 no.4
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• pp.291-297
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• 2018

Coxsackievirus B3 (CVB3) is a very well-known causative agent for viral myocarditis and meningitis in human. However, the effective vaccine and therapeutic drug are not developed yet. CVB3 infection activates host cell AKT signaling. Inhibition of AKT signaling pathway may attenuate CVB3 replication and prevent CVB3-mediate viral myocarditis. In this study, we determined antiviral effect of the selected natural plant extract to develop a therapeutic drug for CVB3 treatment. We screened several chemically extracted natural compounds by using HeLa cell-based cell survival assay. Among them, Linum usitatissimum L. extract was selected for antiviral drug candidate. L. usitatissimum extract significantly decreased CVB3 replication and cell death in CVB3 infected HeLa cells with no cytotoxicity. CVB3 protease 2A induced eIF4G1 cleavage and viral capsid protein VP1 production were dramatically decreased by L. usitatissimum extract treatment. In addition, virus positive and negative strand genome amplification were significantly decreased by 1 mg/ml L. usitatissimum extract treatment. Especially, L. usitatissimum extract was associated with inhibition of AKT signal and maintain mTOR activity. In contrast, Atg12 and LC3 expression were not changed by L. usitatissimum extract treatment. In this study, the potential AKT signal inhibitor, L. usitatissimum extract, was significantly inhibited viral genome replication and protein production by inhibition of AKT signal. These results suggested that L. usitatissimum extract is a novel therapeutic agent for treatment of CVB3-mediated diseases.

• Journal of Biomedical Engineering Research
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• v.39 no.6
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• pp.284-296
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• 2018

Obesity is considered as a primary health problem over the past century in line with life environmental changes. It is mainly associated with increased risk of numerous chronic diseases which may significantly reduce health-related quality of life. Therefore, efforts to reduce weight should be performed. This study suggested a novel approach to reduce body fat by applying external stimulation which is micro-current stimulation (MCS). In this clinical study, we evaluated the potential effects of MCS for reduction of abdominal fat and weight loss. Prior to the clinical test, computational simulation was conducted to find the proper MCS conditions that allow externally applied stimulation to reach the internal fat section from the external skin. Particularly, the clinical study evaluated the unilateral effects of MCS for body fat loss and lipolysis without any additional limitations such as physical exercise and dietary therapy. The results showed that whole body fat, waist circumferences, and abdominal fat are gradually decreased after intervention in proportion to the time. From the results, we can estimate that MCS can be effective on the body fat loss by activation of lipolysis in human adipose.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.04a
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• pp.73-73
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• 2019

전나무속(Abies Miller, 1754)은 지구상에서 북반구를 중심으로 50여 종이 현존하고 있다. 전나무속은 주로 높은 고도의 산지 또는 수목 한계선 주변에 자연적 분포지를 형성하고 있으며, 국내에는 전나무(A. holophylla), 분비나무(A. nephrolepis) 및 구상나무(A. koreana), 총 3종이 자생하고 있다. 하지만 국내에 자생하는 3종의 경우도 쇠퇴가 급격히 진행되고 있다. 특히 대한민국 특산식물인 한라산의 구상나무는 IUCN Redlist 상의 'Threatened species' category 종으로 등재되어 있을 뿐만 아니라 구상나무 어린 나무(치수)의 수가 급격히 줄어 우리 사회에서 문제가 직면한 '저출산 고령화 사회'와 유사하다고 할 수 있다. 하지만, 구상나무의 어린 나무에 관한 연구가 미비한 실정이다. 게다가 선행연구에서도 어린 나무의 기준이 모호하다. 따라서 본 연구는 구상나무 등 국내 자생하는 구상나무 천연묘의 기준을 정립하여 추후 진행되는 구상나무 등 전나무속 어린 나무에 관한 연구에 표준화를 유도할 수 있을 것으로 기대된다. 우선, 국내.외 소나무과 어린나무에 관한 논문을 정리 및 분석하였고, 구상나무 어린나무가 자생하는 숲의 구조(제주조릿대 등) 및 환경(암석노출도) 등)에 적절한 높이와 아린흔의 갯수를 참고로 기준안을 제시해 보고자 한다. 본 연구의 기준안은 선행연구에서 조사된 구상나무 어린나무 3,138개체의 높이 및 아린흔 갯수를 토대로 구분해볼 수 있었다. 우선, 높이에 대한 기준은 1년생묘(당해묘, 5cm 미만)-유묘(5cm~10cm 미만)-성묘(대묘, 10cm~30cm 미만)-치수(30cm~100cm 미만) cf.전생치수-유목(100cm 이상) 5단계로 구분되었다. 아린흔 갯수에 대한 기준도 또한 1년생묘(1개)-유묘(2개~6개)-성묘(대묘, 7개~15개)-치수(16개~20개) cf.전생치수-유목(21개 이상) 5단계로 구분되었다.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.04a
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• pp.74-74
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• 2019

한라산은 남한에서 가장 높은 산으로 해발고도는 1,950m이고 그 면적은 약 9,100ha로 대한민국 최대의 섬제주의 중심에 자리하고 있다. 한라산은 특산식물이 36종이나 발견되어 국내 외적으로 생물적인 가치와 보전적인 가치를 인정받아온 곳이다. 본 연구에서는 한라산 성판악에서 백록담으로 이어지는 동사면의 해발고도 1,500m 부근의 진달래밭대피소 인근에 위치한 5ha 장기생태 연구 지역 식생조사를 통해서 조사된 자생 식물종을 정리하였다. 관속식물은 31과 44속 56종 등 총 56분류군으로 조사되었으며, 조사지역에서 확인된 산림청지정 희귀식물은 구상나무(LC), 주목(VU), 섬매발톱나무(DD), 개족도리풀(LC), 시로미(VU), 게박쥐나물(LC), 사철란(LC) 등 7분류군이 확인되었고, 특산식물로는 구상나무, 족도리풀, 제주조릿대, 산제비란 등 4분류군이 확인되었다. 식물구계학적 특정식물은 I등급은 일엽초, 윤노리나무, 야광나무, 큰천남성 등 6분류군, II등급으로는 두루미꽃, 홍괴불나무, 마가목, 산개벚지나무, 다람쥐꼬리 등 10분류군, III등급은 만년석송, 구상나무, 애기괭이밥, 호자덩굴 등 8분류군, IV등급은 시로미 그리고 V등급은 설앵초가 각각 1분류군으로 조사되었다. 한라산 아고산대의 대표 우점종인 구상나무는 특산식물이자, 식물구계학적 특정식물 III등급이며, 산림청지정 희귀식물 약관심종으로 추가 연구를 통하여 보전관리방안이 수립되어야 하는 것으로 판단된다.

• Korean Journal of Plant Resources
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• v.32 no.5
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• pp.565-588
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• 2019

This study aimed to understand current flora of Western Civilian Control Zone (CCZ) in Korea. Some areas that located at Paju-si and Yeoncheon-gun were selected as representative survey area (Jangdan-myeon, Deokjin mountain fortress, Ilwol peak of Mt. Seokbyeong, Imjinriver, Sunaecheon stream, Sewolcheon stream in Paju and Banjeong-ri in Yeoncheon). Through this survey, 461 vascular plant specimens were collected from April 2012 to September 2014, twice a month and from October 2014 to October 2018, once a month. These were finally classified into 96 families 305 genera 413 species 4 subspecies 41 varieties 6 forms totally 464 taxa. There are remarkable plants such as 6 taxa of Korean endemic species, 44 taxa of specified species on a floristics aspect, and 35 taxa of alien and naturalized plants (7.5%). Meanwhile, it has not been observed any endangered plant species during the activities in this area.

• The Korea Journal of Herbology
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• v.36 no.2
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• pp.19-29
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• 2021

Objective : This study was designed to investigate anti-oxidative, anti-aging and anti-inflammatory activities of Zingiber officinale Roscoe water (ZD) and 50% ethanol extracts (ZE). Method : The antioxidant capacity of ZD or ZE was analyzed by DPPH, ABTS scavenging activities and reducing power, respectively. The anti-aging efficacy was performed with tyrosinase and collagenase inhibition activities. The anti-inflammatory activities were confirmed through inhibition of nitric oxide production and TNF-�� expression in LPS-treated Raw 264.7 cells. Result : As a result of measuring DPPH and ABTS radical scavenging activities, both ZD and ZE extracts increased in concentration-dependent manners. The ABTS radical scavenging activities of water and 50% ethanol extract were similar to that of positive control at high concentration. On reducing power, both ZD and ZE showed higher activities than the positive control at high concentration. On inhibition activities of tyrosinase and collagenase both ZD and ZE showed the large inhibition rates at low concentration. Also, the inhibitory efficacy of ZD on NO and TNF-�� production was better than ZE in RAW 264.7 cells. Conclusion : These results suggest that ZD and ZE have anti-oxidative, anti-aging and anti-inflammatory effects in vitro. Especially, ZD was more effective than ZE. Thus, Ginger extract is considered to be highly useful as a cosmetic or food material with anti-oxidative, anti-aging (prevention of whitening and wrinkle) and anti-inflammatory effects. Also these effects may vary depending on the extraction solvent.

• The Korea Journal of Herbology
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• v.28 no.5
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• pp.29-31
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• 2013

Objectives : 'Reconsideration about Nomenclature of Herbs Listed in the Korean Pharmacopoeia' was published by Doh and Lee with absolute misconception of nomenclature. A critical review of Doh and Lee's paper is given, to correct the confused the concept of nomenclature and to provide proper scientific name for taxa which are discussed. Methods : This paper discusses the proper usage, as mandated by the International Code of Nomenclature. Adherence to the rules described in this paper should reduce the present confusion in the nomenclature of scientific names listed in the Korean Pharmacopoeia. Results : Although Doh and Lee proposed four categories to correct the scientific names of the Korean Pharmacopoeia using available botanical databases, they failed to show how nomenclatural concepts are applicable due to misconception of legitimacy and the confusion about synonym. From a nomenclatural perspective, 'accepted name' or 'recommended name' is a subjective term which used to be employed for convenience in a certain databases or working group without nomenclatural meaning. Doh and Lee also pointed out the standardization of author citation. However, they missed the importance of author citation error such as basionym or validating authors. Conclusions : Doh and Lee were not able to solve nomenclatural problems of the Korea Pharmacopoeia due to lack of clarity on the nomenclature code. We strongly recommend that KFDA has to commence extensive nomenclatural review for the next revision of Korea Pharmacopoeia.