• Title/Summary/Keyword: 한국 제4기학회

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Characterization and Culture Optimization of an Glucosidase Inhibitor-producing Bacteria, Gluconobactor oxydans CK-2165 (α-Glucosidase 저해제 생산 균주, Gluconobacter oxydans CK-2165의 특성 및 배양 최적화)

  • Kim, Byoung-Kook;Suh, Min-Jung;Park, Ji-Su;Park, Jang-Woo;Suh, Jung-Woo;Kim, Jin-Yong;Lee, Sun-Young;Choi, Jongkeun;Suh, Joo-Won;Lee, In-Ae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.11
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    • pp.5179-5186
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    • 2012
  • Miglitol, a well-known therapeutic intervention agents for diabetes, exhibits competitive inhibitory activity against ${\alpha}$-glucosidase and it is usually produced through three sequential steps including chemical and bioconversion processes. Gluconobactor oxydans (G. oxydans) belonging to acetic acid bacteria biologically, converts 1-deoxy-1-(2-hydroxyethylamino)-D-glucitol (P1) into a key intermidiate, 6-(2-hydroxyetyl) amino-6-deoxy-${\alpha}$-L-sorbofuranose (P2) by incomplete oxidation. In this study, we identified and optimized fermentation conditions of CK-2165, that was selected in soil samples by comparing the bioconversion yield. CK-2165 strain was found to be closely related to G. oxydans based on the result of phylogenetic analysis using 16S rDNA sequence. Utilization of API 20 kits revealed that this strain could use glucose, mannose, inositol, sorbitol, rhamnose, sucrose, melibiose, amygdalin and arabinose as carbon sources. The culture conditions were optimized for industrial production and several important factors affecting bioconversion rate were also tested using mycelial cake. Cell harvested at the late-stationary phase showed the highest bioconversion yield and $MgSO_4$ was critically required for the catalytic activity.

Analysis of the Maximum Pressure Difference of PSI(pound per square inch) depending on the Size of the Y-shape Connecting Tube of the Automatic Contrast Medium Injector (CT 검사 시 조영제 자동주입기 Y자 연결관의 크기에 따른 PSI(pound per square inch)의 차이 분석)

  • Kim, Hyeon-jin;Im, In-chul
    • Journal of the Korean Society of Radiology
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    • v.11 no.4
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    • pp.247-252
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    • 2017
  • Radiologists who experience extravasation of the contrast medium even once suffer mentally during testing due to the fear of its reoccurrence. Establishing a plan for preventing it beforehand is necessary above all because patients experience severe physical and mental pain and become distrusting of medical staff and treatment. Therefore, the present study attempts to prevent extravasation, which is the result of damage from pressure applied to the patient's blood vessels, by lowering PSI, and conducted a comparative analysis of PSI changes during contrast medium injection depending on the diameter of the Y-shape connecting tube which connects the automatic injector and the intravenous injection of the patient. In the case of product A in which the diameter of the Y-shape connecting tube is about 2mm, the average PSI for all ages was 98.5 and standard deviation was 9.72. In the case of product B in which the diameter of the Y-shape connecting tube is about 3mm, the average PSI for all ages was 62.0 and standard deviation was 8.59. Product B with its wider diameter decreased in average pressure by 37.05% when compared to product A, and when product B is used with the p-value at 0.00, pressure decreased even more, achieving statistically significant results.

Proposal Strategy and Performance Analysis of Electronic Human Resources Management Pilot Project (건설근로자공제회 전자인력관리(전자카드제)시범사업 성과 분석 및 추진전략 도출)

  • Kim, Inchie;Chin, Sangyoon;Kim, Seongah;Kim, Yeasang;Lee, Sangjun;Park, Soohun
    • Korean Journal of Construction Engineering and Management
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    • v.19 no.4
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    • pp.3-11
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    • 2018
  • The Construction Workers Mutual Aid Association is carrying out a number of strategic tasks with the goal of "contributing to improving employment and stabilizing the return of workers to construction workers through employment welfare and retirement deduction services." One of them is the retirement deduction system. The retirement allowance system is a system for the retirement income and livelihood security of construction workers who are not adequately protected by the Labor Standards Act, such as retirement allowances due to the nature of day labor. The Construction Workers Mutual Aid Association has promoted the introduction of electronic manpower management. For the efficient management of the pilot sites and the plans for the future, comprehensive evaluation of the pilot sites as well as the evaluation of the status and operation results of each pilot project site are needed. Therefore, in this study, we will develop performance indicators to evaluate the current state of electronic manpower pilot projects and analyze the actual situation of pilot project sites through actual application, and try to derive future implementation strategies.

Police Officers' Cognitions of Police Investigation Specialization (수사경과제에 대한 경찰공무원의 인식)

  • Choi, Mu-Chan
    • The Journal of the Korea Contents Association
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    • v.9 no.6
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    • pp.289-299
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    • 2009
  • This study set out to analyze the perceptions of investigative police officers and division police officers regarding Police Investigation Specialization, which had been in effect for four years, identify the problems, and search for alternative policies. The results led to the following alternative policies; first, the communication among the members should be facilitated by trading the jobs between investigative policemen and division members in certain percentage regularly, integrating job education and special work, and developing diverse support programs for detective activities to provide them with opportunities to experience and understand investigation. The second suggestion concerns the investigation members' morale. There should be a range of measures to boost their moral such as allocating separate budget and personnel to support the investigation department and the treatment of major criminal and civil cases, giving each investigation team an office and investigation room to improve their working environment, readjusting the promotion ratio of Police Investigation Specialization to introduce a promotion system proper for each investigation's characteristics. The third suggestion is to secure job efficiency. It's required to reinforce the current short-term specialized education program to bring up practical and professional investigators, open the certification exam of professional investigators to all members so that every policeman can have their abilities recognized and approved as long as they have the demanded capabilities, and create a system of shedding off the members idle at work by reflecting low performance records when evaluating the members to decide who to dismiss from Police Investigation Specialization. And finally, it's important to divide duties rationally. The rationality of duties division can be guaranteed by setting the guidelines for direct handling for the team leader to help him devote himself to his duties, defining objective criteria of measuring investigation workload, and creating devoted systems and teams for simple and small accidents so that experienced investigators can deal with high-profile cases.

A Study for Historical Consideration of "The Golden Age" of Chinese Comics -Focusing on and - (중국만화의 "황금시기"에 관한 역사적 고찰 -<왕 선생>, <삼모 유랑기> 중심으로-)

  • Jin, Li-Na
    • Cartoon and Animation Studies
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    • s.34
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    • pp.197-217
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    • 2014
  • The 1920s and 1930s ushered in "the golden age" of Chinese comics when the comics flourished. Satirical cartoons in modern Chinese comics were popular due to emotional instability and war caused by foreign powers. Among many popular comics, this paper analyzes in the 1920s and in the 1930s which were made into films and dramas. Chapter Two shows that China in the Republican era of China expanded its consumer culture into some sectors like films, novels, magazines and fashion in the 1920s and 1930s. However, more than any other things, this chapter considers from the historical perspective "the golden age" of comics including comic magazine in the 1930s and a history of comic magazines that gained popularity with conventional and common story. Chapter Three explains that social satire cartoons were in vogue since the May Fourth Movement and anti-imperialistic and semi-feudalistic stories in the 1920s were realized in life. It also says that comics that describes the negative sides of its society were popular. Ye QianYu, a cartoonist, portrayed many facets of Shanghai through : the daily life of the middle and lower classes, bureaucratic corruption and sympathy for the working class. drawn by Zhang LePing describes the unfair social system between the bourgeoisie and the proletariat and the gap between the rich and poor through the main character, the powerless and poor orphan. and lampooned the reality of its time in an objective, witty and humorous way in terms of ethics and economy respectively. The researcher chooses to study and which are very familiar to us, because good cartoons, animations and movies stimulate the feelings about our surroundings.

Synthesis and Latent Characteristics of Thermal Cationic Latent Catalysts by Change of Substituent (치환기 변화에 따른 열잠재성 양이온 촉매의 합성과 잠재특성 연구)

  • Park, Soo-Jin;Heo, Gun-Young;Lee, Jae-Rock;Shim, Sang-Yeon;Suh, Dong-Hack
    • Polymer(Korea)
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    • v.25 no.4
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    • pp.558-567
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    • 2001
  • The syntheses of thermal latent catalysts have been carried out by modifying the substituent of pyrazinium salts. The thermal latent properties and cure behaviors of difunctional epoxy resin (diglycidylether of bisphenol-A, DGEBA) with 1 wt% of catalyst as an initiator were investigated by dynamic DSC method. As a result, the synthesized catalysts showed the good latent thermal properties in epoxy system. With increasing the basicity of substituted catalyst, the cure temperature and activation energy of epoxy system were increased, whereas the activity was decreased. This was probably due to the fact that the activity and cure behavior were controlled by ring strain and basicity of substituent. Consequently, the catalyst activity modified by methyl group as an electron donor was decreased in increasing of basicity in an initiation step of epoxy cure system. This is due to a decreasing of stabilities of both leaving group of pyrazinium salts and benzyl cation. However, the catalyst activity modified by cyano group as an electron acceptor was increased in increasing the stability of benzyl cation resulting from organic effects and resonance.

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Application of Extracorporeal Ultrafiltration Therapy Given to a Dog and a Cat with Pulmonary Edema and Renal Failure (폐부종 및 신부전을 동반한 개와 고양이에서 체외초미세여과법을 이용한 치료)

  • Park, Hyung-Jin;Byun, Seok-Young;Choi, Jun-Hyuk;Lee, Jong-Bok;Song, Kun-Ho;Seo, Kyoung-Won
    • Journal of Veterinary Clinics
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    • v.33 no.1
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    • pp.34-38
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    • 2016
  • A 13-year-old castrated male mixed breed dog and a 12-year-old castrated male mixed breed cat were referred to the hospital for the treatment of pulmonary edema and azotemia at the same time. To resolve the pulmonary edema and azotemia, intermittent hemodialysis (HD) was performed using ultrafiltration (UF), and the pulmonary edema, azotemia, other electrolyte and acid-base imbalances were improved. This case study demonstrated that when we encountered pulmonary edema patients with diuretic resistance, severe electrolyte imbalance, and impaired renal function complicated by decongestive therapy using diuretics, UF therapy can be considered a life-saving intervention.

Numerical Experiments of the Seiche in Young-il Bay and Pohang New Harbor, Korea (영일과 포항신항의 해면부진동에 관한 수치실험)

  • 박한일;정종율
    • 한국해양학회지
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    • v.21 no.4
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    • pp.245-258
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    • 1986
  • A two-dimensional numerical model is developed to investigate the phenomenon of forced seiche caused by the incident long waves. This model is applied to Young-il Bay and Pohang New Harbor, where the seiche is most frequently observed and the damage of the seiche is serious compared with the other harbors in Korea. Some results on this study are as follows; 1. The natural periods of the first two modes obtained from the present model are about 70 and 25 minutes respectively for Young-il Bay, and about 25 and 7.5 minutes for Pohang New Harbor. These results are well consistent with those obtained by the theoretical formula, the spectral analysis, and the statistical investigation of the recorded data. 2. Since the fundamental natural period of Pohang New Harbor is almost the same as the second natural period of Young-il Bay, the seiche in Pohang New Harbor can be strongly amplified by the Oscillation in Young-il Bay. Therefore, the most strong seiche in Pohang New Harbor can occur when the long wave of about 25-minute period come into Young-il Bay.

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Influence of Some Pollutants and Fertilizers on Degradation of Oxadixyl in Soil (몇 가지 오염물질과 비료의 처리가 살균제 Oxadixyl의 토양중 분해에 미치는 영향)

  • Moon, Young-Hee;Kim, Yong-Hwi;Kim, Young-Seok
    • Korean Journal of Environmental Agriculture
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    • v.16 no.4
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    • pp.341-346
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    • 1997
  • The degradation of fungicide oxadixyl in soil amended with manure, chemical fertilizers, heavy metals and detergent was studied. The degradation of oxadixyl in the soil was slow, but became to be fast after the lag phase of about 14 days. The half-life was 10.5 days. The degradation rate was accelerated largely by the amendment of manure. Potassium also promoted the degradation rate but nitrogen and phosphate did not. The heavy metals inhibited the degradation rate, in order of Ni, Cd, Cr, Cu, and Zn. The degradation rate was declined greatly with the addition of synthetic detergent. The microbial biomass and the respiration rate in the soil were increased by the amendment of manure and chemical fertilizers, but decreased by the addition of heavy metals and cleaner. The degradation rate of oxadixyl was positively correlated with the microbial biomass and the respiration rate.

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Gel Polymer Electrolytes Derived from a Polysilsesquioxane Crosslinker for Lithium-Sulfur Batteries (리튬-황 전지용 폴리실세스키옥산 고분자 가교제로 제조된 겔 고분자 전해질의 전기화학적 특성)

  • Kim, Eunji;Lee, Albert S.;Lee, Jin Hong
    • Applied Chemistry for Engineering
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    • v.32 no.4
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    • pp.467-471
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    • 2021
  • A ladder-like polysilsesquioxane (LPMA64) functionalized with a crosslinkable group was synthesized and used for the preparation of organic-inorganic hybrid gel polymer electrolytes through a thermal crosslinking process of the liquid electrolytes. A small weight percent of LPMA64 polymer crosslinker (5 wt%) was able to form a well-developed network structure, resulting in good dimensional stability with high ionic conductivity. The lithium-sulfur batteries fabricated with organic-inorganic hybrid gel polymer electrolytes exhibited stable C-rate and cycling performance with excellent Coulombic efficiency due to the alleviated lithium polysulfide shuttling effect during prolonged cycling. The result demonstrates that the organic-inorganic hybrid gel polymer electrolytes could be a promising candidate electrolyte for application in lithium-sulfur batteries.